Cited by 63Substance Abuse Treatment and OutcomesCriminal Law and PolicyCannabis and Cannabinoid Research

Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review

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Scheim, Ayden I, Maghsoudi, Nazlee, Marshall, Zack, Churchill, Siobhan, Ziegler, Carolyn, Werb, Dan·2020·BMJ Open

Abstract

Objectives: To review the metrics and findings of studies evaluating effects of drug decriminalisation or legal regulation on drug availability, use or related health and social harms globally. Design: Systematic review with narrative synthesis. Data sources: We searched MEDLINE, Embase, PsycINFO, Web of Science and six additional databases for publications from 1 January 1970 through 4 October 2018. Inclusion criteria: Peer-reviewed articles or published abstracts in any language with quantitative data on drug availability, use or related health and social harms collected before and after implementation of de jure drug decriminalisation or legal regulation. Data extraction and synthesis: Two independent reviewers screened titles, abstracts and articles for inclusion. Extraction and quality appraisal (modified Downs and Black checklist) were performed by one reviewer and checked by a second, with discrepancies resolved by a third. We coded study-level outcome measures into metric groupings and categorised the estimated direction of association between the legal change and outcomes of interest. Results: We screened 4860 titles and 221 full-texts and included 114 articles. Most (n=104, 91.2%) were from the USA, evaluated cannabis reform (n=109, 95.6%) and focussed on legal regulation (n=96, 84.2%). 224 study outcome measures were categorised into 32 metrics, most commonly prevalence (39.5% of studies), frequency (14.0%) or perceived harmfulness (10.5%) of use of the decriminalised or regulated drug; or use of tobacco, alcohol or other drugs (12.3%). Across all substance use metrics, legal reform was most often not associated with changes in use. Conclusions: Studies evaluating drug decriminalisation and legal regulation are concentrated in the USA and on cannabis legalisation. Despite the range of outcomes potentially impacted by drug law reform, extant research is narrowly focussed, with a particular emphasis on the prevalence of use. Metrics in drug law reform evaluations require improved alignment with relevant health and social outcomes.

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  • The scope of the review was limited to recreational legalization and did not consider other forms of policy changes such as medicinal legalization or decriminalization.

    “Additionally, the scope of the review was limited to recreational legalization and did not consider other forms of policy changes such as medicinal legalization or decriminalization, as these have been summarized more comprehensively in prior reviews.112-114”

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Cited by

Sorted by citations

Authors
Scheim, A. I., Maghsoudi, N., Marshall, Z., Churchill, S., Ziegler, C., & Werb, D.
Affiliations
  • St. Michael's Hospital (CA)
  • McGill University (CA)
  • Western University (CA)
  • Unity Health Toronto (CA)
Corresponding author
Werb, Dan
Venue
BMJ Open
Publisher
BMJ
Published
2020-09
Volume
10
Issue
9
Pages
e035148
ISSN
2044-6055 (ISSN-L)
OpenAlex
W3087726603
Cited by
63
References
7
Citations by year
2026: 7 · 2025: 14 · 2024: 7 · 2023: 18 · 2022: 11 · 2021: 5 · 2020: 1
FWCI
1.28
Type
journal article
Language
en
Open access
Locations
  • BMJ Open (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (acceptedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Open Society Foundations
  • Ontario Ministry of Research, Innovation and Science
  • National Institutes of Health (1dp2da040256-01)
  • Canadian Institutes of Health Research (#SMN-139 150)
  • National Institute on Drug Abuse (DP2-DA040256)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Sociology and Political Science › Criminal Law and Policy
  • Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
Keywords
drug decriminalization, drug policy reform, cannabis legalization, drug use prevalence, substance use outcomes, health damage, social harm, drug availability, evaluation metrics, alcohol and tobacco use
MeSH terms
Cannabis, Pharmaceutical Preparations, Humans, Legislation, Drug, Outcome Assessment, Health Care, Substance-Related Disorders

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