The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Use and abuse of hydrogen breath tests
Open accessAbstract
Hydrogen breath tests are widely used to explore the pathophysiology of functional gastrointestinal disorders. Small intestinal bacterial overgrowth and carbohydrate malabsorption are disorders detected by these tests that have been proposed to be of great importance for symptoms in, for instance, irritable bowel syndrome. However, conclusions drawn from these studies are highly controversial and divergent results exist. There is also an extensive use of these tests in clinical practice with difficulties regarding interpretation of the tests and sometimes erroneous conclusions. The limitations and pitfalls of these tests will be reviewed in this article, and hopefully the occasional abuse of these tests can be turned into proper clinical and scientific use instead in the future.
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Citations
Cites
Functional bowel disorders and functional abdominal pain
Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Müller-Lissner, S. A. (1999) · Gut · doi:10.1136/gut.45.2008.ii43 · Cited by 2,440
Common symptoms in ambulatory care: incidence, evaluation, therapy, and outcome
Kroenke, K., & Mangelsdorff, A. D. (1989) · The American Journal of Medicine · doi:10.1016/0002-9343(89)90293-3 · Cited by 947
Vantrappen, G., Janssens, J., Hellemans, J., & Ghoos, Y. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108740 · Cited by 815
Eradication of Small Intestinal Bacterial Overgrowth Reduces Symptoms of Irritable Bowel Syndrome
Pimentel, M., Chow, E. J., & Lin, H. C. (2000) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03368.x · Cited by 780
Food-Related gastrointestinal symptoms in the irritable bowel syndrome
Simrén, M., Månsson, A., Langkilde, A. M., Svedlund, J., Abrahamsson, H., Bengtsson, U., & Björnsson, E. S. (2001) · Digestion · doi:10.1159/000051878 · Cited by 529
Incomplete absorption of pure fructose in healthy subjects and the facilitating effect of glucose.
Truswell, A., Seach, J., & Thorburn, A. (1988) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/48.6.1424 · Cited by 189
Gender Differences in Gut Transit Shown with a Newly Developed Radiological Procedure
Sadik, R., Abrahamsson, H., & Stotzer, P.-O. (2003) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310000410 · Cited by 183
Self-citationRole of fructose-sorbitol malabsorption in the irritable bowel syndrome
Nelis, G. F., Vermeeren, M. A. P., & Jansen, W. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)90621-7 · Cited by 123
Fasting breath hydrogen in celiac disease
Corazza, G. R., Strocchi, A., & Gasbarrini, G. (1987) · Gastroenterology · doi:10.1016/0016-5085(87)90313-1 · Cited by 101
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Cited by
Postinfectious Irritable Bowel Syndrome
Spiller, R., & Garsed, K. (2009) · Gastroenterology · doi:10.1053/j.gastro.2009.02.074 · Cited by 1,024
Rezaie, A., Buresi, M., Lembo, A., Lin, H., McCallum, R., Rao, S., Schmulson, M., Valdovinos, M., Zakko, S., & Pimentel, M. (2017) · American Journal of Gastroenterology · doi:10.1038/ajg.2017.46 · Cited by 852
Small intestinal bacterial overgrowth syndrome
Bures, J. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i24.2978 · Cited by 620
Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions
Öhman, L., & Simrén, M. (2010) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2010.4 · Cited by 617
Self-citationOng, D. K., Mitchell, S. B., Barrett, J. S., Shepherd, S. J., Irving, P. M., Biesiekierski, J. R., Smith, S., Gibson, P. R., & Muir, J. G. (2010) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2010.06370.x · Cited by 583
Metadata
- Authors
- Simrén, M., & Stotzer, P.-O.
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2006-02-10
- Volume
- 55
- Issue
- 3
- Pages
- 297.1-303
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- OpenAlex
- W2107253188
- Cited by
- 418
- References
- 11
- FWCI
- 19.20
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
