Food-Related gastrointestinal symptoms in the irritable bowel syndrome

Simrén, Magnus; Månsson, Agneta; Langkilde, Anna Maria; Svedlund, Jan; Abrahamsson, Hasse; Bengtsson, Ulf; Björnsson, Einar S.

doi:10.1159/000051878

Cited by 529Gastrointestinal motility and disordersGut microbiota and healthInfant Health and Development

Food-Related gastrointestinal symptoms in the irritable bowel syndrome

Simrén, Magnus, Månsson, Agneta, Langkilde, Anna Maria, Svedlund, Jan, Abrahamsson, Hasse, Bengtsson, Ulf, Björnsson, Einar S.·2001·Digestion

DOI 10.1159/000051878

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Abstract

BACKGROUND/AIMS: Postprandial symptoms are common in patients with irritable bowel syndrome (IBS). However, existing studies have come to different conclusions about the role of food in the pathophysiology of IBS. We explored the prevalence of subjective food-related gastrointestinal (GI) symptoms and its relationship to clinical characteristics and psychological factors in IBS. METHODS: 330 patients with IBS and 80 healthy volunteers completed a food questionnaire developed for this study. The subjects graded their subjective symptoms after 35 different foods and a food score was obtained by adding the item scores. The relationship between subjective food-related GI symptoms and referral status, IBS subgroup (predominant bowel pattern), sex, anxiety, depression and body mass index (BMI) was estimated. RESULTS: In 209 (63%) of the patients the GI symptoms were related to meals. Gas problems and abdominal pain were the most frequently reported symptoms. Foods rich in carbohydrates, as well as fatty food, coffee, alcohol and hot spices were most frequently reported to cause symptoms. The food score was higher in patients than in controls (p < 0.0001). In the IBS group higher scores were observed in patients with anxiety (p = 0.005), and females (p < 0.001), but the results were unrelated to IBS subgroup, referral status or BMI. The BMI did not differ between groups. CONCLUSION: A majority of IBS patients consider their symptoms to be related to meals. Especially foods rich in carbohydrates and fat cause problems. Nevertheless, the majority of IBS patients are normal or overweight. Female sex and anxiety predict a high degree of food-related symptoms in IBS.

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Over 80% of individuals with IBS report food-related symptoms, especially to fermentable carbohydrates and fats.
“Over 80% of individuals with IBS report food-related symptoms, especially to fermentable carbohydrates and fats.188 189”
From British Society of Gastroenterology guidelines on the management of irritable bowel syndrome (2021) · cites this paper as [188]

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Authors: Simrén, M., Månsson, A., Langkilde, A. M., Svedlund, J., Abrahamsson, H., Bengtsson, U., & Björnsson, E. S.
Affiliations: Sahlgrenska University Hospital (SE)
ORCID: Simrén, Magnus
Langkilde, Anna Maria
Svedlund, Jan
Venue: Digestion
Publisher: S. Karger AG
Published: 2001
Volume: 63
Issue: 2
Pages: 108-115
ISSN: 0012-2823 (ISSN-L)
1421-9867
DOI: 10.1159/000051878
OpenAlex: W1975523098
Cited by: 529
References: 40
Citations by year: 2026: 6 · 2025: 21 · 2024: 19 · 2023: 31 · 2022: 37 · 2021: 36 · 2020: 31 · 2019: 35 · 2018: 32 · 2017: 33 · 2016: 31 · 2015: 29 · 2014: 26 · 2013: 25 · 2012: 22
FWCI: 7.52
Type: journal article
Language: en
Open access: closed
Licence: www.karger.com/Services/SiteLicenses (vor)
www.karger.com/Services/SiteLicenses (tdm)
Locations: Digestion (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Health Professions › Pharmacy › Infant Health and Development
Keywords: irritable bowel syndrome, postprandial symptoms, food intolerance, carbohydric foods, fatty foods, anxiety, depression, sex differences, body mass index, abdominal pain, gases
MeSH terms: Adult, Aged, Anxiety, Colonic Diseases, Functional, Depression, Feeding Behavior, Female, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Diet Records, Body Mass Index, Chi-Square Distribution, Statistics, Nonparametric, Postprandial Period

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Food-Related gastrointestinal symptoms in the irritable bowel syndrome

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