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The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota

Open access
Zoetendal, E G, Rajilić-Stojanović, M, de Vos, W M·2008·Gut

Abstract

The human gastrointestinal (GI) tract microbiota plays a pivotal role in our health. For more than a decade a major input for describing the diversity of the GI tract microbiota has been derived from the application of small subunit ribosomal RNA (SSU rRNA)-based technologies. These not only provided a phylogenetic framework of the GI tract microbiota, the majority of which has not yet been cultured, but also advanced insights into the impact of host and environmental factors on the microbiota community structure and dynamics. In addition, it emerged that GI tract microbial communities are host and GI tract location-specific. This complicates establishing relevant links between the host’s health and the presence or abundance of specific microbial populations and argues for the implementation of novel high-throughput technologies in studying the diversity and functionality of the GI tract microbiota. Here, we focus on the recent developments and applications of phylogenetic microarrays based on SSU rRNA sequences and metagenomics approaches exploiting rapid sequencing technologies in unravelling the secrets of our GI tract microbiota.

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Metadata

Authors
Zoetendal, E. G., Rajilić-Stojanović, M., & de Vos, W. M.
Venue
Gut
Publisher
BMJ
Published
2008-10-21
Volume
57
Issue
11
Pages
1605-1615
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
OpenAlex
W2165003751
Cited by
673
References
14
FWCI
17.74
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. https://app.cochat.ai/papers/10.1136/gut.2007.133603
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Zoetendal, E. G., Rajilić-Stojanović, M., & de Vos, W. M. (2008). High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut. https://doi.org/10.1136/gut.2007.133603

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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