Dysbiosis of the gut microbiota in disease
Open accessAbstract
There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular disease, and obesity.
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Changes in microbial equilibrium (dysbiosis) can promote and influence the course of many intestinal and extra-intestinal diseases.
“Changes in this microbial equilibrium that is, dysbiosis can promote and influence the course of many intestinal and extra-intestinal diseases[14-16].”
From Proton pump inhibitors and dysbiosis: current knowledge and aspects to be clarified (2019) · cites this paper as [16]
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Linking the Gut Microbial Ecosystem with the Environment: Does Gut Health Depend on Where We Live?
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- Authors
- Carding, S., Verbeke, K., Vipond, D. T., Corfe, B. M., & Owen, L. J.
- Affiliations
- University of East Anglia (GB)
- KU Leuven (BE)
- Insigneo (GB)
- University of Sheffield (GB)
- Corresponding author
- Corfe, Bernard M.
- Venue
- Microbial Ecology in Health & Disease
- Publisher
- Co-Action Publishing
- Published
- 2015-02-02
- Volume
- 26
- Issue
- 0
- Pages
- 26191-26191
- ISSN
- 0891-060X (ISSN-L)
- 1651-2235
- PMC
- PMC4315779
- OpenAlex
- W1977328678
- Cited by
- 1,710
- References
- 98
- Citations by year
- 2026: 63 · 2025: 145 · 2024: 201 · 2023: 213 · 2022: 217 · 2021: 234 · 2020: 229 · 2019: 133 · 2018: 118 · 2017: 85 · 2016: 53 · 2015: 19
- FWCI
- 39.56
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by-nc-nd
- Locations
- Microbial Ecology in Health and Disease (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- White Rose Research Online (University of Leeds, The University of Sheffield, University of York) (acceptedVersion)
- UEA Digital Repository (University of East Anglia) (acceptedVersion)
- Lirias (KU Leuven) (submittedVersion, other-oa)
- University of Salford Institutional Repository (University of Salford) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- European Science Foundation
- Biotechnology and Biological Sciences Research Council (BBS/E/F/00044446)
- European Social Fund
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Keywords
- gut dysbiosis, intestinal disorders, inflammatory bowel disease, irritable bowel syndrome, celiac disease, allergy, asthma, metabolic syndrome, cardiovascular disease, obesity
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