The effect of optimal medical therapy on 1-year mortality after acute myocardial infarction
Open accessAbstract
Objectives: Five drug classes have been shown to improve the prognosis of acute myocardial infarction in clinical trials: aspirin, β-blockers, statins, renin angiotensin system (RAS) blockers and thienopyridines. We aimed to assess whether the benefits of combining these drugs (termed optimal medical therapy, OMT), will result in a reduction of mortality in clinical practice. Design: Nationwide registry Setting: Hospitals with a cardiology unit or internal medicine department. Patients: 5353 patients with acute myocardial infarction. At hospital discharge 89% received aspirin, 90% β-blockers, 84% statins, 81% RAS blockers, 70% a thienopyridine and 46.2% OMT. Interventions: Pharmacotherapy Main outcome measures: OR with 95% CI for mortality from myocardial infarction were calculated and adjusted for patient risk at baseline. Results: Total mortality was reduced by 74% in patients receiving OMT (adj OR 0.26; 95% CI 0.18 to 0.38) versus patients receiving one or no drug. This was consistent in subgroups defined by STEMI/NSTEMI, diabetes and gender. Mortality was also reduced in patients receiving 2–4 drugs (adj OR 0.49; 95% CI 0.35 to 0.68), diabetic patients being the only subgroup with no significant effect. Analyses on the relative importance of either component revealed that withdrawal of β-blockers (adj OR 0.63; 95% CI 0.34 to 1.16) and/or a combination of aspirin/clopidogrel (adj OR 0.59; 95% CI 0.20 to 1.17) abolished the risk reduction conferred by OMT. Conclusions: OMT over 1 year was associated with a significantly lower mortality of patients with acute myocardial infarction in clinical practice. However OMT is provided to less than half of eligible patients leaving room for substantial improvement.
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In an observational study of 5353 patients with acute myocardial infarction, only about half were discharged with optimal medical therapy compared with guideline standards.
“However, only about half of all patients were discharged with optimal medical therapy in an observational study of 5353 patients with acute myocardial infarction compared with the standards in these guidelines.555”
From European Guidelines on cardiovascular disease prevention in clinical practice (version 2012) (2012) · cites this paper as [555]
Patients discharged on less than optimal medical therapy have a worse 1-year prognosis.
“patients discharged on less than optimal medical therapy have a worse 1-year prognosis.555”
From European Guidelines on cardiovascular disease prevention in clinical practice (version 2012) (2012) · cites this paper as [555]
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Prasugrel versus clopidogrel in patients with acute coronary syndromes
Wiviott, S. D., Braunwald, E., McCabe, C. H., Montalescot, G., Ruzyllo, W., Gottlieb, S., Neumann, F.-J., Ardissino, D., De Servi, S., Murphy, S. A., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa0706482 · Cited by 6,790 · see citing works
D, E. B. M., Antman, E. M., Beasley, J. W., Califf, R. M., Cheitlin, M. D., Hochman, J. S., Jones, R. H., Kereiakes, D. J., Kupersmith, J., Levin, T. N., et al. (2000) · Circulation · doi:10.1161/01.cir.102.10.1193 · Cited by 4,474 · see citing works
Fox, K. A. A., Dabbous, O. H., Goldberg, R. J., Pieper, K. S., Eagle, K. A., de Werf, F. V., Avezum, Á., Goodman, S. G., Flather, M. D., Anderson, F. A., et al. (2006) · BMJ · doi:10.1136/bmj.38985.646481.55 · Cited by 1,699 · see citing works
Pitt, B., Segal, R., Martínez, F. A., Meurers, G., Cowley, A. J., Thomas, I., DEEDWANIA, P. C., Ney, D. E., Snavely, D. B., & Chang, P. (1997) · The Lancet · doi:10.1016/s0140-6736(97)01187-2 · Cited by 1,656 · see citing works
Tunstall-Pedoe, H., Kuulasmaa, K., Mähönen, M., Tolonen, H., & Ruokokoski, E. (1999) · The Lancet · doi:10.1016/s0140-6736(99)04021-0 · Cited by 1,444 · see citing works
D, E. B. M., Antman, E. M., Beasley, J. W., Califf, R. M., Cheitlin, M. D., Hochman, J. S., Jones, R. H., Kereiakes, D. J., Kupersmith, J., Levin, T. N., et al. (2002) · Circulation · doi:10.1161/01.cir.0000037106.76139.53 · Cited by 844 · see citing works
Impact of Medication Therapy Discontinuation on Mortality After Myocardial Infarction
Ho, P. M., Spertus, J. A., Masoudi, F. A., Reid, K. J., Peterson, E. D., Magid, D. J., Krumholz, H. M., & Rumsfeld, J. S. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.17.1842 · Cited by 635 · see citing works
The APEX AMI Investigators (2007) · JAMA · doi:10.1001/jama.297.1.43 · Cited by 447 · see citing works
Wiviott, S. D., Cannon, C. P., Morrow, D. A., Ray, K. K., Pfeffer, M. A., & D, E. B. M. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.04.064 · Cited by 340 · see citing works
Mukherjee, D., Fang, J., Chetcuti, S. J., Moscucci, M. M., Kline-Rogers, E. M., & Eagle, K. A. (2004) · Circulation · doi:10.1161/01.cir.0000112577.69066.cb · Cited by 315 · see citing works
Gislason, G., Rasmussen, J. N., Abildstrom, S. Z., Gadsbøll, N., Buch, P., Friberg, J., Rasmussen, S., Køber, L., Stender, S., Madsen, M., et al. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehi705 · Cited by 301 · see citing works
Eagle, K. A., Kline-Rogers, E. M., Goodman, S. G., Gurfinkel, E., Avezum, Á., Flather, M. D., Granger, C. B., Erickson, S. R., White, K., & Steg, P. G. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2003.12.041 · Cited by 226 · see citing works
Smith, S. C., Jr. (2019) · PubMed · doi:10.17615/vf9y-es17 · Cited by 185 · see citing works
Yan, A. T.-K., Yan, R. T., Tan, M., Huynh, T. T., Soghrati, K., Brunner, L. J., DeYoung, P., FITCHETT, D. H., Langer, A., & Goodman, S. G. (2007) · American Heart Journal · doi:10.1016/j.ahj.2007.07.040 · Cited by 144 · see citing works
Roe, M. T., Peterson, E. D., Newby, L. K., Chen, A. Y., Pollack, C. V., Brindis, R. G., Harrington, R. A., Christenson, R. H., Smith, S. C., Califf, R. M., et al. (2006) · American Heart Journal · doi:10.1016/j.ahj.2005.08.006 · Cited by 139 · see citing works
Blackburn, D. F., Dobson, R. T., Blackburn, J. L., Wilson, T. W., Stang, M. R., & Semchuk, W. (2005) · PubMed · Cited by 122 · see citing works
Mehta, R. H., Montoye, C., Faul, J. D., Nagle, D., Kure, J., Raj, E., Fattal, P. G., Sharrif, S., Amlani, M., Changezi, H., et al. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.08.067 · Cited by 114 · see citing works
Medication performance measures and mortality following acute coronary syndromes
Granger, C. B., Steg, P. G., Peterson, E. D., Lopez-Sendon, J. L., de Werf, F. V., Kline-Rogers, E. M., Allegrone, J., Dabbous, O. H., Klein, W. W., Fox, K. A. A., et al. (2005) · The American Journal of Medicine · doi:10.1016/j.amjmed.2005.01.070 · Cited by 100 · see citing works
Patient adherence: the next frontier in quality improvement
Heidenreich, P. A. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.03.007 · Cited by 74 · see citing works
Trends in community mortality due to coronary heart disease
Goldberg, R. J., Glatfelter, K., Burbank-Schmidt, E., Lessard, D., & Gore, J. M. (2006) · American Heart Journal · doi:10.1016/j.ahj.2005.04.024 · Cited by 65 · see citing works
Temporal decline in the prognostic impact of a recurrent acute myocardial infarction 1985 to 2002
Buch, P., Rasmussen, S., Gislason, G., Rasmussen, J. N., Køber, L., Gadsbøll, N., Stender, S., Madsen, M., Torp-Pedersen, C. T., & Abildstrom, S. Z. (2006) · Heart · doi:10.1136/hrt.2006.092213 · Cited by 55 · see citing works
Allen, L. A., O’Donnell, C. J., Giugliano, R. P., Camargo, C. A., & Lloyd‐Jones, D. M. (2004) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.01.063 · Cited by 45 · see citing works
Bonello, L., de Labriolle, A., Roy, P. K., Steinberg, D. H., Okabe, T., Slottow, T. L. P., Xue, Z., Torguson, R., Suddath, W. O., Satler, L. F., et al. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.04.040 · Cited by 43 · see citing works
Gersh, B. J. (2007) · Yearbook of Cardiology · doi:10.1016/s0145-4145(08)70140-0 · Cited by 40 · see citing works
Gersh, B. J. (2008) · Yearbook of Medicine · doi:10.1016/s0084-3873(08)79252-6 · Cited by 20 · see citing works
Gersh, B. J. (2008) · Yearbook of Cardiology · doi:10.1016/s0145-4145(08)04035-5 · Cited by 20 · see citing works
Mehta, R., Montoye, C. K., & Faulet, J. (2004) · ACC Current Journal Review · doi:10.1016/j.accreview.2004.07.120 · Cited by 9 · see citing works
Rückgang der Krankenhaus-Sterblichkeit und verbesserte Sekundärprävention nach akutem Myokardinfarkt
Tebbe, U., Messer, C., Stammwitz, E., The, G., Dietl, J., Bischoff, K.-O., Schulten-Baumer, U., Tebbenjohanns, J., Gohlke, H., & Bramlage, P. (2007) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-2007-984934 · Cited by 5 · see citing works
Self-citation
Flagged first, then by citations
1 of the 31 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Heart 2010;96:604e609. doi:10.1136/hrt.2009.188607 Acute coronary syndrome on August 24, 2023 by guest. Protected by copyright. http://heart.bmj.com/ Heart: first published as 10.1136/hrt.2009.188607 on 29 March 2010. Downloaded from REFERENCES
- Tebbe U, Messer C, Stammwitz E, et al. [Reduction of in-hospital mortality and improved secondary prevention after acute myocardial infarction. First results from the registry of secondary prevention after acute myocardial infarction (SAMI)]. Dtsch Med Wochenschr 2007;132:1559e66.
Cited by
Sorted by citations
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)
Authors/Task Force Members:, Perk, J., De Backer, G., Gohlke, H., Graham, I., Reiner, Ž., Verschuren, M., Albus, C., Benlian, P., Boysen, G., et al. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehs092 · Cited by 8,490 · see citing works
Self-citation2016 European Guidelines on cardiovascular disease prevention in clinical practice
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M.-T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw106 · Cited by 6,457 · see citing works
European guidelines on cardiovascular disease prevention in clinical practice: executive summary
Graham, I., Atar, D., Borch‐Johnsen, K., Boysen, G., Burell, G. K., Cífková, R., Dallongeville, J., Backer, G. D., Ebrahim, S. B. J., Gjelsvik, B., et al. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehm316 · Cited by 3,840 · see citing works
2016 European Guidelines on cardiovascular disease prevention in clinical practice
Authors/Task Force Members, Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M. T., Corrà, U., Cosyns, B., et al. (2016) · European Journal of Preventive Cardiology · doi:10.1177/2047487316653709 · Cited by 1,409 · see citing works
Authors/Task Force Members: Joep Perk (Chairperson) (Sweden)*, G. D. B. (. (2012) · European Journal of Preventive Cardiology · doi:10.1177/2047487312450228 · Cited by 863 · see citing works
European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)
Perk, J., Backer, G. D., Gohlke, H., Graham, I. M., Reiner, Ž., Verschuren, W. M. M., Albus, C., Benlian, P., Boysen, G., Cífková, R., et al. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.05.007 · Cited by 693 · see citing works
Self-citation2016 European Guidelines on cardiovascular disease prevention in clinical practice
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M. T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.05.037 · Cited by 488 · see citing works
European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (Version 2012)
Perk, J., Backer, G. D., Gohlke, H., Graham, I. M., Reiner, Ž., Verschuren, W. M. M., Albus, C., Benlian, P., Boysen, G., Cífková, R., et al. (2012) · International Journal of Behavioral Medicine · doi:10.1007/s12529-012-9242-5 · Cited by 313 · see citing works
Self-citationF. Piepoli, M. (2017) · International Journal of Behavioral Medicine · doi:10.1007/s12529-016-9583-6 · Cited by 162 · see citing works
2016 European Guidelines on cardiovascular disease prevention in clinical practice
Piepoli, M. F., Hoes, A. W., Agewall, S., Albus, C., Brotons, C., Catapano, A. L., Cooney, M. T., Corrà, U., Cosyns, B., Deaton, C., et al. (2016) · Kardiologia Polska · doi:10.5603/kp.2016.0120 · Cited by 143 · see citing works
Ma, T., Wong, I. C. K., Man, K. K. C., Chen, Y., Crake, T., Ozkor, M. A., Ding, L., Wang, Z., Zhang, L., & Wei, L. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210988 · Cited by 85 · see citing works
García‐García, C., Subirana, I., Sala, J., Bruguera, J., Sanz, G., Valle, V., Arós, F., Fiol, M., Balaguer, L. M., Serra, J., et al. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.06.003 · Cited by 79 · see citing works
Ozasa, N., Kimura, T., Morimoto, T., Hou, H., Tamura, T., Shizuta, S., Nakagawa, Y., Furukawa, Y., Hayashi, Y., Nakao, K., et al. (2010) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2010.06.048 · Cited by 72 · see citing works
KONES, R. J. (2010) · Vascular Health and Risk Management · doi:10.2147/vhrm.s11100 · Cited by 63 · see citing works
Impact of Optimal Medical Therapy on 10-Year Mortality After Coronary Revascularization
Kawashima, H., Serruys, P. W. J. C., Ono, M., Hara, H., O’Leary, N., Mack, M. J., Holmes, D. R., Morice, M., Head, S. J., Kappetein, A. P., et al. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.04.087 · Cited by 61 · see citing works
Excess mortality and guideline-indicated care following non-ST-elevation myocardial infarction
Dondo, T. B., Hall, M., Timmis, A., Gilthorpe, M. S., Alabas, O., Batin, P. D., Deanfield, J. E., Hemingway, H., & Gale, C. P. (2016) · European Heart Journal Acute Cardiovascular Care · doi:10.1177/2048872616647705 · Cited by 45 · see citing works
Optimal combination secondary prevention drug treatment and stroke outcomes
Park, J., & Ovbiagele, B. I. (2014) · Neurology · doi:10.1212/wnl.0000000000001099 · Cited by 41 · see citing works
Optimal Model of Comprehensive Rehabilitation and Secondary Prevention
Jankowski, P., Niewada, M., Bochenek, A. A., Bochenek−Klimczyk, K., Bogucki, M., Drygas, W., Dudek, D., Eysymontt, Z., Grajek, S., Kozierkiewicz, A., et al. (2013) · Kardiologia Polska · doi:10.5603/kp.2013.0246 · Cited by 35 · see citing works
Alexithymia: A facet of uncontrolled hypertension
Casagrande, M., Mingarelli, A., Guarino, A., Favieri, F., Boncompagni, I., Germanò, R., Germanò, G., & Forte, G. (2019) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2019.09.006 · Cited by 35 · see citing works
Antoni, M. L., Hoogslag, G. E., Boden, H., Liem, S., Boersma, E. H., Fox, K. M., Schalij, M. J., Bax, J. J., & Delgado, V. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.08.029 · Cited by 32 · see citing works
Meimoun, P., Clerc, J., Vincent, C., Flahaut, F., Germain, A. L., Elmkies, F., Zemir, H., & Luycx-Bore, A. (2012) · European Heart Journal - Cardiovascular Imaging · doi:10.1093/ehjci/jes192 · Cited by 32 · see citing works
Gnjidic, D., Bennett, A., Couteur, D. G. L., Blyth, F., Cumming, R. G., Waite, L. M., Handelsman, D. J., Naganathan, V., Matthews, S. T., & Hilmer, S. N. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.05.045 · Cited by 30 · see citing works
Al-Zakwani, I. S., Zubaid, M., Panduranga, P., Rashed, W. A., Sulaiman, K., Almahmeed, W. A., Al‐Motarreb, A., Suwaidi, J. M. S. A., & Amin, H. (2011) · Angiology · doi:10.1177/0003319710394163 · Cited by 29 · see citing works
Gunnell, A. S., Einarsdóttir, K., Sanfilippo, F. M., Liew, D., Holman, C. D. J., & Briffa, T. G. (2013) · Heart · doi:10.1136/heartjnl-2013-304348 · Cited by 28 · see citing works
Amann, U., Kirchberger, I., Heier, M., Golüke, H., von Scheidt, W., Kuch, B., Peters, A., & Meisinger, C. (2014) · Clinical Research in Cardiology · doi:10.1007/s00392-014-0688-0 · Cited by 27 · see citing works
Polypill and Global Cardiovascular Health Strategies
Sanz, G., & Fuster, V. (2011) · Seminars in Thoracic and Cardiovascular Surgery · doi:10.1053/j.semtcvs.2011.05.005 · Cited by 27 · see citing works
Ge, Z., Baber, U., Claessen, B. E. P. M., Farhan, S., Chandrasekhar, J., Li, S. X., Sartori, S., Kini, A. S., Rao, S. V., Weiss, S. A., et al. (2018) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.27860 · Cited by 27 · see citing works
Hemingway, H., Feder, G. S., Fitzpatrick, N. K., Denaxas, S., Shah, A. D., & Timmis, A. (2017) · Programme Grants for Applied Research · doi:10.3310/pgfar05040 · Cited by 27 · see citing works
Royo‐Bordonada, M. Á., Bejarano, J. M. L., Álvarez, F. V., Sans, S., Pérez, A., Pedro‐Botet, J., Carriles, R. M. M., Maiques, A., Lizcano‐Álvarez, A., Lizarbe, V., et al. (2013) · Revista Española de Salud Pública · doi:10.4321/s1135-57272013000200002 · Cited by 26 · see citing works
Royo‐Bordonada, M. Á., Bejarano, J. M. L., Álvarez, F. V., Sans, S., Pérez, A., Pedro‐Botet, J., Carriles, R. M. M., Maiques, A., Lizcano‐Álvarez, A., Lizarbe, V., et al. (2013) · Hipertensión y Riesgo Vascular · doi:10.1016/j.hipert.2013.04.003 · Cited by 26 · see citing works
Exercise as the master polypill of the 21st century for the prevention of cardiovascular disease
Sanchis‐Gomar, F., Fiuza‐Luces, C., & Lucía, A. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.12.048 · Cited by 23 · see citing works
Bertelsen, J. B., Refsgaard, J. C., Kanstrup, H., Johnsen, S. P., Qvist, I., Christensen, B., & Christensen, K. L. (2016) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515116666781 · Cited by 22 · see citing works
Impact of Optimal Medical Therapy in the Dual Antiplatelet Therapy Study
Resor, C. D., Nathan, A. S., Kereiakes, D. J., Yeh, R. W., Massaro, J. M., Cutlip, D. E., Steg, P. G., Hsieh, W.-H., & Mauri, L. (2016) · Circulation · doi:10.1161/circulationaha.116.024531 · Cited by 21 · see citing works
Jánosi, A., Ofner, P., Merkely, B. P., Polgár, P., Zámolyi, K., Kiss, R. G., Edes, I. F., Csapó, K., Nagy, L., Lupkovics, G., et al. (2013) · Orvosi Hetilap · doi:10.1556/oh.2013.29679 · Cited by 21 · see citing works
Hay, M., Stehli, J., Martin, C., Brennan, A., Dinh, D. T., Lefkovits, J., & Zaman, S. J. (2020) · European Journal of Preventive Cardiology · doi:10.1177/2047487319900875 · Cited by 21 · see citing works
Her, A., Choi, B. G., Rha, S., Kim, Y. H., Choi, C. U., & Jeong, M. H. (2020) · PLoS ONE · doi:10.1371/journal.pone.0242314 · Cited by 20 · see citing works
Lee, Y.-H., Park, J., Tahk, S., Hwang, G., Yoon, M., Choi, S., Choi, B., Lim, H., Yang, H., Seo, K., et al. (2015) · Cardiology · doi:10.1159/000431077 · Cited by 20 · see citing works
Gausia, K., Katzenellenbogen, J. M., Sanfilippo, F. M., Knuiman, M. W., Thompson, P. L., Hobbs, M., & Thompson, S. (2014) · Internal Medicine Journal · doi:10.1111/imj.12375 · Cited by 20 · see citing works
Zeymer, U., Berkenboom, G. M., Coufal, Z., Belger, M. A., Sartral, M., Norrbacka, K., & Bakhai, A. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2013.10.057 · Cited by 19 · see citing works
Carolina Nazzal, N., Frenz, P., Alonso, F. T., & Lanas, F. T. (2015) · Health Policy and Planning · doi:10.1093/heapol/czv120 · Cited by 19 · see citing works
Gale, C. P., Metcalfe, E., West, R. M., Das, R., Kilcullen, N. M., Morrell, C., Crook, R. E., Batin, P. D., Hall, A. S., & Barth, J. H. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.06.041 · Cited by 18 · see citing works
Lee, K., Han, S., Lee, M., Kim, D., Kwon, J.-B., Park, G., & Park, M. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.121.024370 · Cited by 17 · see citing works
Chrischilles, E. A., Schneider, K. M., Schroeder, M. C., Letuchy, E. M., Wallace, R. B., Robinson, J. G., & Brooks, J. M. (2016) · Journal of the American Geriatrics Society · doi:10.1111/jgs.13953 · Cited by 17 · see citing works
Looi, K. L., Chow, K. L., Looi, J., Lee, M., Halliday, S., White, H. D., & Ellis, C. (2011) · PubMed · Cited by 16 · see citing works
Jabri, A. M., Assad, H., & Al‐Jumaili, A. A. (2020) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2020.02.009 · Cited by 16 · see citing works
Case, R., George, J., Li, Q., Arnaoutakis, G. J., & Keeley, E. C. (2019) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2019.08.005 · Cited by 15 · see citing works
Al-Khadra, S., Meisinger, C., Amann, U., Holle, R., Kuch, B., Seidl, H., & Kirchberger, I. (2014) · Drugs & Aging · doi:10.1007/s40266-014-0189-x · Cited by 15 · see citing works
Zhang, L., Shi, J., Pan, Y., Li, Z., Yan, H., Liu, C., Lv, W., Meng, X., & Wang, Y. (2021) · Stroke and Vascular Neurology · doi:10.1136/svn-2020-000471 · Cited by 14 · see citing works
Sotorra‐Figuerola, G., Ouchi, D., Giner‐Soriano, M., & Morros, R. (2021) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.5261 · Cited by 13 · see citing works
Chen, Y., Tang, X., Gao, R.-L., Yang, Y., Xu, B., & Yuan, J. (2020) · Cardiovascular Therapeutics · doi:10.1155/2020/4351469 · Cited by 12 · see citing works
Secondary prevention: Where we are
Corrà, U., & Piepoli, M. F. (2017) · European Journal of Preventive Cardiology · doi:10.1177/2047487317704978 · Cited by 12 · see citing works
on behalf of the CCR Study Investigators, Yetgin, T., van der Linden, M. M. J. M., de Vries, A. G., Smits, P. C., van Mechelen, R., Yap, S., Boersma, E. H., Zijlstra, F., & van Geuns, R. (2013) · Netherlands Heart Journal · doi:10.1007/s12471-013-0484-x · Cited by 11 · see citing works
Velásquez‐Rodríguez, J., Bruña, V., Vicent, L., Díez‐Delhoyo, F., Valero‐Masa, M. J., Sousa-Casasnovas, I., Juárez, M., Devesa, C., Fernández‐Avilés, F., & Martínez‐Sellés, M. (2021) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2020.07.017 · Cited by 11 · see citing works
Oliveras, T., Massot, M. F., Abadal, A. C., Rueda, F., Flores, J. S., Carrillo, X., & Bayés‐Genís, A. (2014) · International Journal of Cardiology · doi:10.1016/j.ijcard.2014.09.029 · Cited by 10 · see citing works
Богачевская, С. А., & Николаевич, Б. А. (2017) · Social Aspects of Population Health · doi:10.21045/2071-5021-2017-53-1-1 · Cited by 10 · see citing works
Redón, J., Usó, R., Trillo-Mata, J. L., López, C., Morales‐Olivas, F. J., Navarro, J., Sanchís, J. M., Gil, V., & Orozco‐Beltrán, D. (2019) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.05.071 · Cited by 10 · see citing works
Carolina Nazzal, N., Lanas, F. T., Garmendia, M. L., Bugueño, C., Mercadal, E., Eduardo Garcés, S., Yovaniniz, P., & Sanhueza, P. (2013) · Revista médica de Chile · doi:10.4067/s0034-98872013000800003 · Cited by 10 · see citing works
Blöndal, M. (2012) · DSpace repository (University of Tartu) · Cited by 10 · see citing works
Ahn, W. J., Rha, S., Choi, B. G., Jeong, M. H., Ahn, T. H., Yoon, J., Kim, H.-S., Seung, K., Gwon, H., Chae, S. C., et al. (2023) · Heart and Vessels · doi:10.1007/s00380-023-02244-x · Cited by 9 · see citing works
Statins and myocardial infarction: Type, dose, and administration time: Does it matter?
Παπαγεωργίου, Ν., Zacharia, E. M., Briasoulis, Α., Androulakis, E. S., & Tousoulis, D. (2016) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2016.01.001 · Cited by 8 · see citing works
Alonso, F. T., Carolina Nazzal, N., Cerecera, F., & Ojeda, J. I. (2018) · International Journal of Health Services · doi:10.1177/0020731418809851 · Cited by 8 · see citing works
Quality of medical management in coronary artery disease
Shammeri, O. A., Stafford, R. S., Alzenaidi, A., Al-Hutaly, B., & Elmoniem, A. E. A. (2014) · Annals of Saudi Medicine · doi:10.5144/0256-4947.2014.488 · Cited by 7 · see citing works
George, N. E., Shukkoor, A. A., Joseph, N., Palanimuthu, R., Kaliappan, T., & Gopalan, R. (2022) · The Egyptian Heart Journal · doi:10.1186/s43044-021-00237-7 · Cited by 7 · see citing works
Chen, L., Han, L., & Luo, J.-G. (2019) · Medicine · doi:10.1097/md.0000000000016544 · Cited by 6 · see citing works
Kobayashi, S., Sakakura, K., Jinnouchi, H., Taniguchi, Y., Tsukui, T., Hatori, M., Watanabe, Y., Yamamoto, K., Seguchi, M., Wada, H., et al. (2023) · Journal of Cardiology · doi:10.1016/j.jjcc.2023.09.013 · Cited by 5 · see citing works
Determinants of Insufficient Optimal Medical Therapy after Acute Myocardial Infarction
Haraguchi, Y., Sakakura, K., Yamamoto, K., Taniguchi, Y., Tsukui, T., Seguchi, M., Wada, H., Momomura, S., & Fujita, H. (2020) · Internal Medicine · doi:10.2169/internalmedicine.4016-19 · Cited by 5 · see citing works
Pająk, A. (2016) · Kardiologia Polska · doi:10.5603/kp.2016.0052 · Cited by 5 · see citing works
Park, J., Kim, S. H., Kim, M., Lee, J., Choi, Y., Kim, H., Kim, T. O., Kang, D., Ahn, J., Yoo, J. Y., et al. (2023) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2023.06.083 · Cited by 4 · see citing works
Fischer, A. J., Feld, J., Lange, S. A., Günster, C., Dröge, P., Engelbertz, C. M., Ruhnke, T., Gerß, J., Reinecke, H., & Köppe, J. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13133788 · Cited by 4 · see citing works
López, A. P., Almiñana, M. A., & Peris, J. (2020) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2019.11.012 · Cited by 4 · see citing works
Zhang, D., Song, X., Raposeiras‐Roubín, S., Abu‐Assi, E., Henriques, J. P. S., D’Ascenzo, F., Saucedo, J., González‐Juanatey, J. R., Wilton, S. B., Kikkert, W. J., et al. (2020) · International Journal of Cardiology · doi:10.1016/j.ijcard.2020.06.021 · Cited by 4 · see citing works
Cupples, M., & Heron, N. (2016) · Monaldi Archives for Chest Disease · doi:10.4081/monaldi.2016.755 · Cited by 4 · see citing works
Royo‐Bordonada, M. Á., Bejarano, J. M. L., Alvarez, F. V., Sans, S., Pérez, A., Pedro‐Botet, J., Carriles, R. M. M., Maiques, A., Lizcano‐Álvarez, A., Lizarbe, V., et al. (2013) · Neurología · doi:10.1016/j.nrl.2013.04.011 · Cited by 3 · see citing works
Knight, C. J., & Timmis, A. (2011) · Heart · doi:10.1136/heartjnl-2011-300979 · Cited by 3 · see citing works
Royo‐Bordonada, M. Á., Bejarano, J. M. L., Alvarez, F. V., Sans, S., Pérez, A., Pedro‐Botet, J., Carriles, R. M. M., Maiques, A., Lizcano‐Álvarez, A., Lizarbe, V., et al. (2013) · Clínica e Investigación en Arteriosclerosis · doi:10.1016/j.arteri.2013.03.003 · Cited by 3 · see citing works
Vrints, C. J., Wood, D., Zamorano, J. L., Zannad, F. M., Karadeniz, Ş., Mezzani, A., Prescott, E., Ebrahim, S. B. J., Germanò, G., Hobbs, R. F., et al. (2013) · Cited by 3 · see citing works
Self-citationImpact of diabetes on long-term mortality after presentation with acute myocardial infarction
Gale, C. P., Thow, J. C., Batin, P. D., & Hall, A. S. (2011) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e328346a710 · Cited by 3 · see citing works
Belicza, É., Lám, J., & Kósa, I. (2016) · Orvosi Hetilap · doi:10.1556/650.2016.30561 · Cited by 3 · see citing works
The Lessons of COURAGE for the Management of Stable Coronary Artery Disease
Kottke, T. E. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.02.047 · Cited by 3 · see citing works
Zhang, D., Gao, H., Song, X., Raposeiras‐Roubín, S., Abu‐Assi, E., Henriques, J. P. S., D’Ascenzo, F., Saucedo, J., González‐Juanatey, J. R., Wilton, S. B., et al. (2023) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2023.110833 · Cited by 2 · see citing works
de la Hera, J. M., Delgado, E., Martínez‐Camblor, P., Vegas, J. M., García-Ruiz, J. M., & Lambert, J. L. (2012) · Revista Española de Cardiología · doi:10.1016/j.recesp.2012.02.023 · Cited by 2 · see citing works
de la Hera, J. M., Delgado, E., Martínez‐Camblor, P., Vegas, J. M., García-Ruiz, J. M., & Rodríguez‐Lambert, J. L. (2012) · Revista Española de Cardiología (English Edition) · doi:10.1016/j.rec.2012.02.022 · Cited by 2 · see citing works
Reasons for Not Meeting Coronary Artery Disease Targets of Care in Ambulatory Practice
Kottke, T. E., Ogwang, Z., & Smith, J. C. (2010) · The Permanente Journal · doi:10.7812/tpp/10-073 · Cited by 2 · see citing works
López, A. P., Almiñana, M. A., & Peris, J. (2020) · Medicina Clínica · doi:10.1016/j.medcli.2019.11.008 · Cited by 2 · see citing works
Schroeder, M. C., Chapman, C. G., Chrischilles, E. A., Wilwert, J. M., Schneider, K. M., Robinson, J. G., & Brooks, J. M. (2022) · Pharmacy · doi:10.3390/pharmacy10060147 · Cited by 2 · see citing works
Perk, J., Backer, G. D., Gohlke, H., Graham, I. M., Reiner, Ž., Verschuren, W. M. M., Albus, C., Benlian, P., Boysen, G., Cífková, R., et al. (2012) · Ghent University Academic Bibliography (Ghent University) · Cited by 2 · see citing works
Self-citationKnight, C. J., & Timmis, A. (2012) · The Egyptian Heart Journal · doi:10.1016/j.ehj.2012.02.006 · Cited by 2 · see citing works
Temporal Data Mining in Electronic Medical Records from Patients with Acute Coronary Syndrome
Black, W. (2014) · ResearchWorks at the University of Washington (University of Washington) · Cited by 2 · see citing works
Beyond Cholesterol in the Primary Prevention of Cardiovascular Disease: Is The Polypill the Answer?
Sanz, G. (2010) · Current Cardiovascular Risk Reports · doi:10.1007/s12170-010-0135-3 · Cited by 1 · see citing works
Coronary artery disease: medical therapy
Ker, J. (2010) · South African Family Practice · doi:10.1080/20786204.2010.10873994 · Cited by 1 · see citing works
Knight, C. J., & Timmis, A. (2012) · Srce i krvni sudovi · doi:10.5937/siks1202090k · Cited by 1 · see citing works
Al-Hadithy, D. A., Al-Maqbali, J. S., Al-Riyami, A. B., Za’abi, M. A., & Al-Zakwani, I. S. (2023) · Pharmacy · doi:10.3390/pharmacy11030079 · Cited by 1 · see citing works
β-blocker therapy after acute myocardial infarction
Tabrizchi, R. (2013) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.13.15 · Cited by 1 · see citing works
Hyun, S. J., Byun, J. K., Rha, S., Choi, B. G., Choi, S. Y., Cha, J., Jeong, M. H., & the other Korea Acute Myocardial Infarction Registry (KAMIR) investigators (2023) · Journal of Cardiovascular Intervention · doi:10.54912/jci.2023.0008 · Cited by 1 · see citing works
Stellenwert der Lyse im Rettungswesen
Hochreuther, S., Härtel, D., Brockmeier, J., Rohde, M., Machalke, K., Mendrok, H.-C., Bramlage, P., & Tebbe, U. (2013) · Notfall + Rettungsmedizin · doi:10.1007/s10049-013-1727-5 · Cited by 1 · see citing works
Self-citationComments on an acute myocardial infarction study
Tormen, W. C., da Rosa, E. M., & Viecceli, C. (2010) · Heart · doi:10.1136/hrt.2010.205674 · Cited by 1 · see citing works
Bundle branch block in ST-elevation myocardial infarction: evidence for action.
Antman, E. M. (2010) · PubMed
La llamada polipill: ¿una solución o un problema?
Álvarez, L., & Sanz, G. (2011) · Revista Española de Cardiología Suplementos · doi:10.1016/s1131-3587(11)15010-4
Aschenbrenner, T., Brockmeier, J., Bramlage, P., Fimmers, R., Cuneo, A., Hochreuther, S., Zemmrich, C., & Tebbe, U. (2012) · BMC Research Notes · doi:10.1186/1756-0500-5-382
Self-citation
- Authors
- Bramlage, P., Messer, C., Bitterlich, N., Pohlmann, C., Cuneo, A., Stammwitz, E., Tebbenjohanns, J., Gohlke, H., Senges, J., & Tebbe, U.
- Affiliations
- Klinikum Lippe (DE)
- Klinikum Lüdenscheid (DE)
- Universitäts-Herzzentrum Freiburg-Bad Krozingen (DE)
- Heidelberg University (DE)
- Corresponding author
- Tebbe, U
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2010-03-29
- Volume
- 96
- Issue
- 8
- Pages
- 604-609
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- OpenAlex
- W2162467404
- Cited by
- 115
- References
- 31
- Citations by year
- 2024: 1 · 2023: 9 · 2022: 2 · 2021: 6 · 2020: 8 · 2019: 5 · 2018: 2 · 2017: 5 · 2016: 13 · 2015: 4 · 2014: 11 · 2013: 14 · 2012: 15
- FWCI
- 10.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Heart (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Acute Myocardial Infarction Research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Antiplatelet Therapy and Cardiovascular Diseases
- Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
- Keywords
- acute myocardial infarction, optimal medical therapy, one-year mortality, aspirin, beta-blockers, statins, renin-angiotensin system inhibitors, thienopyridines, clopidogrel, drug combination therapy, diabetes mellitus, guideline adherence, pharmacotherapy
- MeSH terms
- Aged, Cardiovascular Agents, Drug Therapy, Combination, Female, Hospitalization, Humans, Male, Middle Aged, Myocardial Infarction, Prospective Studies
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