European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)

Authors/Task Force Members: Joep Perk (Chairperson) (Sweden)*, Guy De Backer (Belgium), Helmut Gohlke (Germany), Ian Graham (Ireland), Željko Reiner (Croatia), WM Monique Verschuren (The Netherlands), Christian Albus (Germany), Pascale Benlian (France), Gudrun Boysen (Denmark), Renata Cifkova (Czech Republic), Christi Deaton (UK), Shah Ebrahim (UK), Miles Fisher (UK), Giuseppe Germano (Italy), Richard Hobbs (UK), Arno Hoes (The Netherlands), Sehnaz Karadeniz (Turkey), Alessandro Mezzani (Italy), Eva Presco

doi:10.1177/2047487312450228

Cited by 863Clinical practice guidelines implementationHealth Promotion and Cardiovascular PreventionCardiovascular Health and Risk Factors

European Guidelines on cardiovascular disease prevention in clinical practice (version 2012): The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)

Authors/Task Force Members: Joep Perk (Chairperson) (Sweden)*, Guy De Backer (Belgium), Helmut Gohlke (Germany), Ian Graham (Ireland), Željko Reiner (Croatia), WM Monique Verschuren (The Netherlands), Christian Albus (Germany), Pascale Benlian (France), Gudrun Boysen (Denmark), Renata Cifkova (Czech Republic), Christi Deaton (UK), Shah Ebrahim (UK), Miles Fisher (UK), Giuseppe Germano (Italy), Richard Hobbs (UK), Arno Hoes (The Netherlands), Sehnaz Karadeniz (Turkey), Alessandro Mezzani (Italy), Eva Presco·2012·European Journal of Preventive Cardiology

DOI 10.1177/2047487312450228

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Abstract

Other experts who contributed to parts of the guidelines: Marie Therese Cooney (Ireland). ESC Committee for Practice Guidelines (CPG): Jeroen Bax (Chairman) (The Netherlands), Helmut Baumgartner (Germany), Claudio Ceconi (Italy), Veronica Dean (France), Christi Deaton (UK), Robert Fagard (Belgium), Christian Funck-Brentano (France), David Hasdai (Israel), Arno Hoes (The Netherlands), Paulus Kirchhof (Germany), Juhani Knuuti (Finland), Philippe Kolh (Belgium), Theresa McDonagh (UK), Cyril Moulin (France), Bogdan A. Popescu (Romania), Željko Reiner (Croatia), Udo Sechtem (Germany), Per Anton Sirnes (Norway), Michal Tendera (Poland), Adam Torbicki (Poland), Alec Vahanian (France), Stephan Windecker (Switzerland) Document Reviewers: Christian Funck-Brentano (CPG Review Coordinator) (France), Per Anton Sirnes (CPG Review Coordinator) (Norway), Victor Aboyans (France), Eduardo Alegria Ezquerra (Spain), Colin Baigent (UK), Carlos Brotons (Spain), Gunilla Burell (Sweden), Antonio Ceriello (Spain), Johan De Sutter (Belgium), Jaap Deckers (The Netherlands), Stefano Del Prato (Italy), Hans-Christoph Diener (Germany), Donna Fitzsimons (UK), Zlatko Fras (Slovenia), Rainer Hambrecht (Germany), Piotr Jankowski (Poland), Ulrich Keil (Germany), Mike Kirby (UK), Mogens Lytken Larsen (Denmark), Giuseppe Mancia (Italy), Athanasios J. Manolis (Greece), John McMurray (UK), Andrzej Pająk (Poland), Alexander Parkhomenko (Ukraine), Loukianos Rallidis (Greece), Fausto Rigo (Italy), Evangelista Rocha (…

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In primary prevention among individuals with no previous cardiovascular events, the net benefit of aspirin is more controversial.
“In primary prevention, however, among individuals with no previous cardiovascular events, its net benefit is more controversial (156,168).”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [168]
Aspirin has been shown to be effective in reducing cardiovascular morbidity and mortality in high-risk individuals with previous MI or stroke (secondary prevention).
“Aspirin has been shown to be effective in reducing cardiovascular morbidity and mortality in high-risk individuals with previous MI or stroke (secondary prevention) and is strongly recommended.”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [168]
For people with documented ASCVD, use of aspirin for secondary prevention has far greater benefit than risk.
“For people with documented ASCVD, use of aspirin for secondary prevention has far greater benefit than risk; for this indication, aspirin is still recommended (168).”
From 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes—2026 (2026) · cites this paper as [168]

GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Guyatt, G. H., Oxman, A. D., Vist, G. E., Kunz, R., Falck-Ytter, Y., Alonso-Coello, P., & Schünemann, H. J. (2008) · BMJ · doi:10.1136/bmj.39489.470347.ad · Cited by 23,305 · see citing works
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
(1998) · The Lancet · doi:10.1016/s0140-6736(98)07019-6 · Cited by 20,023 · see citing works
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17018-9 · Cited by 12,026 · see citing works
The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults
Young, T., Palta, M., Dempsey, J., Skatrud, J., Weber, S., & Badr, S. (1993) · New England Journal of Medicine · doi:10.1056/nejm199304293281704 · Cited by 10,183 · see citing works
Adherence to medication.
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974 · see citing works
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
(2008) · New England Journal of Medicine · doi:10.1056/nejmoa0802987 · Cited by 7,397 · see citing works
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
Wallentin, L., Becker, R. C., Budaj, A., Cannon, C. P., Emanuelsson, H., Held, C., Horrow, J., Husted, S., James, S., Katus, H., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0904327 · Cited by 7,117 · see citing works
Prasugrel versus clopidogrel in patients with acute coronary syndromes
Wiviott, S. D., Braunwald, E., McCabe, C. H., Montalescot, G., Ruzyllo, W., Gottlieb, S., Neumann, F.-J., Ardissino, D., De Servi, S., Murphy, S. A., et al. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa0706482 · Cited by 6,790 · see citing works
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
(2001) · New England Journal of Medicine · doi:10.1056/nejmoa010746 · Cited by 6,470 · see citing works
Effects on Blood Pressure of Reduced Dietary Sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet
Sacks, F. M., Svetkey, L. P., Vollmer, W. M., Appel, L. J., Bray, G. A., Harsha, D., Obarzanek, E., Conlin, P. R., Miller, E. R., Simons-Morton, D. G., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440101 · Cited by 5,638 · see citing works
Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project
Conroy, R. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)00114-3 · Cited by 5,290 · see citing works
Glucose control and vascular complications in veterans with type 2 diabetes
Duckworth, W., Abraira, C., Moritz, T., Reda, D., Emanuele, N., Reaven, P. D., Zieve, F. J., Marks, J., Davis, S. N., Hayward, R., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808431 · Cited by 4,762 · see citing works
Carotid-Artery Intima and Media Thickness as a Risk Factor for Myocardial Infarction and Stroke in Older Adults
O'Leary, D. H., Polak, J. F., Kronmal, R. A., Manolio, T. A., Burke, G. L., & Wolfson, S. K. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901073400103 · Cited by 4,685 · see citing works
Blood pressure, stroke, and coronary heart disease *1Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias
MACMAHON, S. (1990) · The Lancet · doi:10.1016/0140-6736(90)90878-9 · Cited by 4,253 · see citing works
ESC/EAS Guidelines for the management of dyslipidaemias
Reiner, Ž., Catapano, A. L., De Backer, G., Graham, I., Taskinen, M.-R., Wiklund, O., Agewall, S., Alegria, E., Chapman, M. J., Durrington, P., et al. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr158 · Cited by 3,549 · see citing works
Effect of a multifactorial intervention on mortality in type 2 diabetes
Gæde, P., Lund-Andersen, H., Parving, H.-H., & Pedersen, O. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706245 · Cited by 3,489 · see citing works
What is ‘quality of evidence’ and why is it important to clinicians?
Guyatt, G. H., Oxman, A. D., Kunz, R., Vist, G. E., Falck-Ytter, Y., & Schünemann, H. J. (2008) · BMJ · doi:10.1136/bmj.39490.551019.be · Cited by 3,250 · see citing works
Forecasting the Future of Cardiovascular Disease in the United States: A Policy Statement From the American Heart Association
Heidenreich, P. A., Trogdon, J. G., Khavjou, O. A., Butler, J., Dracup, K., Ezekowitz, M. D., Finkelstein, E. A., Hong, Y., Johnston, S. C., Khera, A., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31820a55f5 · Cited by 3,208 · see citing works
Obesity and Cardiovascular Disease: Pathophysiology, Evaluation, and Effect of Weight Loss: An Update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease From the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism
Poirier, P., Giles, T. D., Bray, G. A., Hong, Y., Stern, J. S., Pi-Sunyer, F. X., & Eckel, R. H. (2006) · Circulation · doi:10.1161/circulationaha.106.171016 · Cited by 3,165 · see citing works
Cardiorespiratory Fitness as a Quantitative Predictor of All-Cause Mortality and Cardiovascular Events in Healthy Men and Women: A Meta-analysis
Kodama, S. (2009) · JAMA · doi:10.1001/jama.2009.681 · Cited by 3,035 · see citing works
Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case–control study
Yusuf, S., Hawken, S., Ôunpuu, S., Bautista, L., Franzosi, M. G., Commerford, P., Lang, C. C., Rumboldt, Z., Onen, C. L., Lisheng, L., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67663-5 · Cited by 2,903 · see citing works
Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies
Law, M. R., Morris, J. K., & Wald, N. J. (2009) · BMJ · doi:10.1136/bmj.b1665 · Cited by 2,775 · see citing works
The pathophysiology of cigarette smoking and cardiovascular disease
Ambrose, J. A., & Barua, R. S. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.12.047 · Cited by 2,394 · see citing works
Obesity and Cardiovascular Disease
Lavie, C. J., Milani, R. V., & Ventura, H. O. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.12.068 · Cited by 2,326 · see citing works
Body-mass index and mortality among 1.46 million white adults
Berrington de Gonzalez, A., Hartge, P., Cerhan, J. R., Flint, A. J., Hannan, L., MacInnis, R. J., Moore, S. C., Tobias, G. S., Anton-Culver, H., Freeman, L. B., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1000367 · Cited by 2,317 · see citing works
Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials
Taylor, R. S., Brown, A., Ebrahim, S., Jolliffe, J., Noorani, H., Rees, K., Skidmore, B., Stone, J. A., Thompson, D. R., & Oldridge, N. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.01.009 · Cited by 2,239 · see citing works
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
Nordestgaard, B. G., Benn, M., Schnohr, P., & Tybjærg-Hansen, A. (2007) · JAMA · doi:10.1001/jama.298.3.299 · Cited by 2,058 · see citing works
Effect of Very High-Intensity Statin Therapy on Regression of Coronary Atherosclerosis: The ASTEROID Trial
Nissen, S. E., Nicholls, S. J., Sipahi, I., Libby, P., Raichlen, J. S., Ballantyne, C. M., Davignon, J., Erbel, R., Fruchart, J. C., Tardif, J.-C., et al. (2006) · JAMA · doi:10.1001/jama.295.13.jpc60002 · Cited by 2,047 · see citing works
Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987–1993
Chambless, L. E., Heiss, G., Folsom, A. R., Rosamond, W., Szklo, M., Sharrett, A. R., & Clegg, L. X. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009302 · Cited by 1,990 · see citing works
Risk of myocardial infarction in patients with psoriasis
Gelfand, J. M., Neimann, A. L., Shin, D. B., Wang, X., Margolis, D. J., & Troxel, A. B. (2006) · JAMA · doi:10.1001/jama.296.14.1735 · Cited by 1,899 · see citing works
2007 ESH-ESC Practice Guidelines for the Management of Arterial Hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension
Mancia, G., De Backer, G., Dominiczak, A., Cifkova, R., Fagard, R., Germano, G., Grassi, G., Heagerty, A. M., Kjeldsen, S. E., Laurent, S., et al. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e3282f0580f · Cited by 1,837 · see citing works
Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
Schünemann, H. J., Oxman, A. D., Brozek, J., Glasziou, P., Jaeschke, R., Vist, G. E., Williams, J. W., Kunz, R., Craig, J., Montori, V. M., et al. (2008) · BMJ · doi:10.1136/bmj.39500.677199.ae · Cited by 1,782 · see citing works
Collaborative care for patients with depression and chronic illnesses
Katon, W. J., Lin, E. H. B., Von Korff, M., Ciechanowski, P., Ludman, E. J., Young, B., Peterson, D., Rutter, C. M., McGregor, M., & McCulloch, D. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1003955 · Cited by 1,697 · see citing works
Sugar-Sweetened Beverages, Obesity, Type 2 Diabetes Mellitus, and Cardiovascular Disease Risk
Malik, V. S., Popkin, B. M., Bray, G. A., Després, J.-P., & Hu, F. B. (2010) · Circulation · doi:10.1161/circulationaha.109.876185 · Cited by 1,641 · see citing works
beta Blockade after myocardial infarction: systematic review and meta regression analysis
Freemantle, N., Cleland, J., Young, P., Mason, J., & Harrison, J. (1999) · BMJ · doi:10.1136/bmj.318.7200.1730 · Cited by 1,509 · see citing works
Medication Adherence: Its Importance in Cardiovascular Outcomes
Ho, P. M., Bryson, C. L., & Rumsfeld, J. S. (2009) · Circulation · doi:10.1161/circulationaha.108.768986 · Cited by 1,488 · see citing works
Chronic Kidney Disease: Effects on the Cardiovascular System
Schiffrin, E. L., Lipman, M. L., & Mann, J. F. E. (2007) · Circulation · doi:10.1161/circulationaha.106.678342 · Cited by 1,448 · see citing works
A meta-analysis of the association between adherence to drug therapy and mortality
Simpson, S. H., Eurich, D. T., Majumdar, S. R., Padwal, R. S., Tsuyuki, R. T., Varney, J., & Johnson, J. A. (2006) · BMJ · doi:10.1136/bmj.38875.675486.55 · Cited by 1,353 · see citing works
Projected effect of dietary salt reductions on future cardiovascular disease
Bibbins-Domingo, K., Chertow, G. M., Coxson, P. G., Moran, A., Lightwood, J. M., Pletcher, M. J., & Goldman, L. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0907355 · Cited by 1,253 · see citing works
Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease
Siri-Tarino, P. W., Sun, Q., Hu, F. B., & Krauss, R. M. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27725 · Cited by 1,253 · see citing works
The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice
Rozanski, A., Blumenthal, J. A., Davidson, K. W., Saab, P. G., & Kubzansky, L. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.12.005 · Cited by 1,238 · see citing works
The Effects of a Smoking Cessation Intervention on 14.5-Year Mortality: A Randomized Clinical Trial
Anthonisen, N. R., Skeans, M. A., Wise, R. A., Manfreda, J., Kanner, R. E., Connett, J. E., & for the Lung Health Study Research Group* (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-4-200502150-00005 · Cited by 1,237 · see citing works
A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke
Mohr, J. P., Thompson, J. L. P., Lazar, R. M., Levin, B., Sacco, R. L., Furie, K. L., Kistler, J. P., Albers, G. W., Pettigrew, L. C., Adams, H. P., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011258 · Cited by 1,168 · see citing works
Fruit and vegetable consumption and stroke: meta-analysis of cohort studies
He, F. J., Nowson, C. A., & MacGregor, G. A. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68069-0 · Cited by 1,108 · see citing works
Comparison of body mass index, waist circumference, and waist/hip ratio in predicting incident diabetes: a meta-analysis
Vazquez, G., Duval, S., Jacobs, D. R., & Silventoinen, K. (2007) · Epidemiologic Reviews · doi:10.1093/epirev/mxm008 · Cited by 976 · see citing works
Interventions to Promote Physical Activity and Dietary Lifestyle Changes for Cardiovascular Risk Factor Reduction in Adults: A Scientific Statement From the American Heart Association
Artinian, N. T., Fletcher, G. F., Mozaffarian, D., Kris-Etherton, P., Van Horn, L., Lichtenstein, A. H., Kumanyika, S., Kraus, W. E., Fleg, J. L., Redeker, N. S., et al. (2010) · Circulation · doi:10.1161/cir.0b013e3181e8edf1 · Cited by 919 · see citing works
Lifestyle and risk factor management and use of drug therapies in coronary patients from 15 countries. Principal results from EUROASPIRE II Euro Heart Survey Programme
(2001) · European Heart Journal · doi:10.1053/euhj.2001.2610 · Cited by 893 · see citing works
Cardiovascular prevention guidelines in daily practice: a comparison of EUROASPIRE I, II, and III surveys in eight European countries
Kotseva, K., Wood, D., De Backer, G., De Bacquer, D., Pyörälä, K., & Keil, U. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60330-5 · Cited by 833 · see citing works
EUROASPIRE III: a survey on the lifestyle, risk factors and use of cardioprotective drug therapies in coronary patients from 22 European countries
Kotseva, K., Wood, D., Backer, G. D., Bacquer, D. D., Pyörälä, K., Keil, U., & EUROASPIRE Study Group (2009) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3283294b1d · Cited by 812 · see citing works
The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials
Brugts, J. J., Yetgin, T., Hoeks, S. E., Gotto, A. M., Shepherd, J., Westendorp, R. G. J., de Craen, A. J. M., Knopp, R. H., Nakamura, H., Ridker, P., et al. (2009) · BMJ · doi:10.1136/bmj.b2376 · Cited by 792 · see citing works
Long-term follow-up after tight control of blood pressure in type 2 diabetes
Holman, R. R., Paul, S. K., Bethel, M. A., Neil, H. A. W., & Matthews, D. R. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0806359 · Cited by 762 · see citing works
Percutaneous Coronary Angioplasty Compared With Exercise Training in Patients With Stable Coronary Artery Disease: A Randomized Trial
Hambrecht, R., Walther, C., Möbius-Winkler, S., Gielen, S., Linke, A., Conradi, K., Erbs, S., Kluge, R., Kendziorra, K., Sabri, O., et al. (2004) · Circulation · doi:10.1161/01.cir.0000121360.31954.1f · Cited by 752 · see citing works
Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly
Nichol, K. L., Nordin, J., Mullooly, J., Lask, R., Fillbrandt, K., & Iwane, M. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa025028 · Cited by 752 · see citing works
Prediction of coronary events with electron beam computed tomography
Arad, Y., Spadaro, L. A., Goodman, K., Newstein, D., & Guerci, A. D. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00872-x · Cited by 744 · see citing works
Plant sterol and stanol margarines and health
Law, M. (2000) · BMJ · doi:10.1136/bmj.320.7238.861 · Cited by 729 · see citing works
Physical fitness and activity as separate heart disease risk factors: a meta-analysis
WILLIAMS, P. T. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200105000-00012 · Cited by 724 · see citing works
Long-Term Risk of Mortality Associated With Selective and Combined Elevation in Office, Home, and Ambulatory Blood Pressure
Mancia, G., Facchetti, R., Bombelli, M., Grassi, G., & Sega, R. (2006) · Hypertension · doi:10.1161/01.hyp.0000215363.69793.bb · Cited by 691 · see citing works
Work stress and coronary heart disease: what are the mechanisms?
Chandola, T., Britton, A., Brunner, E., Hemingway, H., Malik, M., Kumari, M., Badrick, E., Kivimaki, M., & Marmot, M. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehm584 · Cited by 673 · see citing works
AHA/ACC Guidelines for Preventing Heart Attack and Death in Patients With Atherosclerotic Cardiovascular Disease: 2001 Update: A Statement for Healthcare Professionals From the American Heart Association and the American College of Cardiology
Smith, S. C., Blair, S. N., Bonow, R. O., Brass, L. M., Cerqueira, M. D., Dracup, K., Fuster, V., Gotto, A., Grundy, S. M., Miller, N. H., et al. (2001) · Circulation · doi:10.1161/hc3801.097475 · Cited by 661 · see citing works
Smoking and risk of myocardial infarction in women and men: longitudinal population study
Prescott, E., Hippe, M., Schnohr, P., Hein, H. O., & Vestbo, J. (1998) · BMJ · doi:10.1136/bmj.316.7137.1043 · Cited by 660 · see citing works
Social Support, Depression, and Mortality During the First Year After Myocardial Infarction
Frasure-Smith, N., Lespérance, F., Gravel, G., Masson, A., Juneau, M., Talajic, M., & Bourassa, M. G. (2000) · Circulation · doi:10.1161/01.cir.101.16.1919 · Cited by 632 · see citing works
Aspirin for Prevention of Cardiovascular Events in a General Population Screened for a Low Ankle Brachial Index<subtitle>A Randomized Controlled Trial</subtitle>
Fowkes, F. G. R. (2010) · JAMA · doi:10.1001/jama.2010.221 · Cited by 624 · see citing works
Passive smoking and the risk of coronary heart disease—a meta-analysis of epidemiologic studies
He, J., Vupputuri, S., Allen, K., Prerost, M. R., Hughes, J., & Whelton, P. K. (1999) · New England Journal of Medicine · doi:10.1056/nejm199903253401204 · Cited by 616 · see citing works
OMEGA, a randomized, placebo-controlled trial to test the effect of highly purified omega-3 fatty acids on top of modern guideline-adjusted therapy after myocardial infarction
Rauch, B., Schiele, R., Schneider, S., Diller, F., Victor, N., Gohlke, H., Gottwik, M., Steinbeck, G., Del Castillo, U., Sack, R., et al. (2010) · Circulation · doi:10.1161/circulationaha.110.948562 · Cited by 607 · see citing works
Sweetened beverage consumption and risk of coronary heart disease in women
Fung, T. T., Malik, V., Rexrode, K. M., Manson, J. E., Willett, W. C., & Hu, F. B. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.27140 · Cited by 601 · see citing works
Coronary Heart Disease Mortality Among Young Adults in the U.S. From 1980 Through 2002
Ford, E. S., & Capewell, S. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.05.056 · Cited by 589 · see citing works
Value of Primordial and Primary Prevention for Cardiovascular Disease: A Policy Statement From the American Heart Association
Weintraub, W. S., Daniels, S. R., Burke, L. E., Franklin, B. A., Goff, D. C., Hayman, L. L., Lloyd-Jones, D., Pandey, D. K., Sanchez, E. J., Schram, A. P., et al. (2011) · Circulation · doi:10.1161/cir.0b013e3182285a81 · Cited by 541 · see citing works
The ankle brachial index is associated with leg function and physical activity: the Walking and Leg Circulation Study
McDermott, M. M., Greenland, P., Liu, K., Guralnik, J. M., Celic, L., Criqui, M. H., Chan, C., Martin, G. J., Schneider, J., Pearce, W. H., et al. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-12-200206180-00008 · Cited by 532 · see citing works
Physical activity and all-cause mortality: an updated meta-analysis with different intensity categories
Löllgen, H., Böckenhoff, A., & Knapp, G. (2009) · International Journal of Sports Medicine · doi:10.1055/s-0028-1128150 · Cited by 529 · see citing works
Effect of Lowering LDL Cholesterol Substantially Below Currently Recommended Levels in Patients With Coronary Heart Disease and Diabetes
Shepherd, J., Barter, P., Carmena, R., Deedwania, P., Fruchart, J.-C., Haffner, S., Hsia, J., Breazna, A., LaRosa, J., Grundy, S., et al. (2006) · Diabetes Care · doi:10.2337/dc05-2465 · Cited by 525 · see citing works
A meta-analysis of psychoeducational programs for coronary heart disease patients.
Dusseldorp, E., van Elderen, T., Maes, S., Meulman, J., & Kraaij, V. (1999) · Health Psychology · doi:10.1037/0278-6133.18.5.506 · Cited by 524 · see citing works
Depression and Medication Adherence in Outpatients With Coronary Heart Disease: Findings From the Heart and Soul Study
Gehi, A., Haas, D., Pipkin, S., & Whooley, M. A. (2005) · Archives of Internal Medicine · doi:10.1001/archinte.165.21.2508 · Cited by 488 · see citing works
Forecasting the effects of obesity and smoking on U.S. life expectancy
Stewart, S. T., Cutler, D. M., & Rosen, A. B. (2009) · New England Journal of Medicine · doi:10.1056/nejmsa0900459 · Cited by 478 · see citing works
Correlation of coronary calcification and angiographically documented stenoses in patients with suspected coronary artery disease: results of 1,764 patients
Haberl, R., Becker, A., Leber, A., Knez, A., Becker, C., Lang, C., Brüning, R., Reiser, M., & Steinbeck, G. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01119-0 · Cited by 472 · see citing works
Trends in smoking behaviour between 1985 and 2000 in nine European countries by education
Giskes, K., Kunst, A. E., Benach, J., Borrell, C., Costa, G., Dahl, E., Dalstra, J. A. A., Federico, B., Helmert, U., Judge, K., et al. (2005) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2004.025684 · Cited by 472 · see citing works
Exercise training in patients with chronic heart failure: Fig 1: Authors' reply
Piepoli, M. F., & Francis, D. P. (2004) · BMJ · doi:10.1136/bmj.328.7441.711-b · Cited by 472 · see citing works
Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a randomised placebo controlled trial
Galan, P., Kesse-Guyot, E., Czernichow, S., Briancon, S., Blacher, J., Hercberg, S., & for the SU.FOL.OM3 Collaborative Group (2010) · BMJ · doi:10.1136/bmj.c6273 · Cited by 457 · see citing works
Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative
Culver, A. L. (2012) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.625 · Cited by 444 · see citing works
Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study
Neil, A., Cooper, J., Betteridge, J., Capps, N., McDowell, I., Durrington, P., Seed, M., Humphries, S. E., & on behalf of the Simon Broome Familial Hyperlipidaemia Register Group (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn422 · Cited by 425 · see citing works
Global Secondary Prevention Strategies to Limit Event Recurrence After Myocardial Infarction: Results of the GOSPEL Study, a Multicenter, Randomized Controlled Trial From the Italian Cardiac Rehabilitation Network
Giannuzzi, P. (2008) · Archives of Internal Medicine · doi:10.1001/archinte.168.20.2194 · Cited by 411 · see citing works
Quantitative effects on cardiovascular risk factors and coronary heart disease risk of replacing partially hydrogenated vegetable oils with other fats and oils
Mozaffarian, D., & Clarke, R. (2009) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1602976 · Cited by 410 · see citing works
Sleep-disordered Breathing and Coronary Artery Disease
MOOE, T., FRANKLIN, K. A., HOLMSTRÖM, K., RABBEN, T., & WIKLUND, U. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.10.2101072 · Cited by 401 · see citing works
Physician communication when prescribing new medications
Tarn, D. M., Heritage, J., Paterniti, D. A., Hays, R. D., Kravitz, R. L., & Wenger, N. S. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.17.1855 · Cited by 400 · see citing works
Aspirin for primary prevention of cardiovascular events in people with diabetes: meta-analysis of randomised controlled trials
De Berardis, G., Sacco, M., Strippoli, G. F. M., Pellegrini, F., Graziano, G., Tognoni, G., & Nicolucci, A. (2009) · BMJ · doi:10.1136/bmj.b4531 · Cited by 395 · see citing works
Salt reduction lowers cardiovascular risk: meta-analysis of outcome trials
He, F. J., & MacGregor, G. A. (2011) · The Lancet · doi:10.1016/s0140-6736(11)61174-4 · Cited by 391 · see citing works
β-Blockers in Congestive Heart Failure: A Bayesian Meta-Analysis
Brophy, J. M., Joseph, L., & Rouleau, J. L. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-7-200104030-00008 · Cited by 389 · see citing works
Prognostic Association of Anxiety Post Myocardial Infarction With Mortality and New Cardiac Events: A Meta-Analysis
Roest, A. M., Martens, E. J., Denollet, J., & de Jonge, P. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181dbff97 · Cited by 388 · see citing works
Methotrexate reduces incidence of vascular diseases in veterans with psoriasis or rheumatoid arthritis
PRODANOWICH, S., MA, F., TAYLOR, J., PEZON, C., FASIHI, T., & KIRSNER, R. (2005) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2004.06.017 · Cited by 384 · see citing works
Peak oxygen intake and cardiac mortality in women referred for cardiac rehabilitation
Kavanagh, T., Mertens, D. J., Hamm, L. F., Beyene, J., Kennedy, J., Corey, P., & Shephard, R. J. (2003) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.07.028 · Cited by 380 · see citing works
Motivational interviewing
Rollnick, S., Butler, C. C., Kinnersley, P., Gregory, J., & Mash, B. (2010) · BMJ · doi:10.1136/bmj.c1900 · Cited by 379 · see citing works
Social support and coronary heart disease: epidemiologic evidence and implications for treatment
Lett, H. S., Blumenthal, J. A., Babyak, M. A., Strauman, T. J., Robins, C., & Sherwood, A. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000188393.73571.0a · Cited by 377 · see citing works
Fish Consumption and Incidence of Stroke: A Meta-Analysis of Cohort Studies
He, K., Song, Y., Daviglus, M. L., Liu, K., Van Horn, L., Dyer, A. R., Goldbourt, U., & Greenland, P. (2004) · Stroke · doi:10.1161/01.str.0000130856.31468.47 · Cited by 371 · see citing works
Meta-Analysis of the Relationship Between Non–High-Density Lipoprotein Cholesterol Reduction and Coronary Heart Disease Risk
Robinson, J. G., Wang, S., Smith, B. J., & Jacobson, T. A. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.10.024 · Cited by 368 · see citing works
Association between a literature-based genetic risk score and cardiovascular events in women
Paynter, N. P. (2010) · JAMA · doi:10.1001/jama.2010.119 · Cited by 361 · see citing works
Systematic review: glucose control and cardiovascular disease in type 2 diabetes
Kelly, T. N., Bazzano, L. A., Fonseca, V. A., Thethi, T. K., Reynolds, K., & He, J. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-6-200909150-00137 · Cited by 358 · see citing works
The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review
Westlake, S. L., Colebatch, A. N., Baird, J., Kiely, P., Quinn, M., Choy, E., Ostor, A. J. K., & Edwards, C. J. (2010) · Rheumatology · doi:10.1093/rheumatology/kep366 · Cited by 357 · see citing works
Early and Late Benefits of High-Dose Atorvastatin in Patients With Acute Coronary Syndromes
Ray, K. K., Cannon, C. P., McCabe, C. H., Cairns, R., Tonkin, A. M., Sacks, F. M., Jackson, G., & Braunwald, E. (2005) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.03.077 · Cited by 356 · see citing works
Lipoprotein metabolism and lipid management in chronic kidney disease
Kwan, B. C. H., Kronenberg, F., Beddhu, S., & Cheung, A. K. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006091006 · Cited by 354 · see citing works
Enhanced Depression Care for Patients With Acute Coronary Syndrome and Persistent Depressive Symptoms: Coronary Psychosocial Evaluation Studies Randomized Controlled Trial
Davidson, K. W., Rieckmann, N., Clemow, L., Schwartz, J. E., Shimbo, D., Medina, V., Albanese, G., Kronish, I., Hegel, M., & Burg, M. M. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.29 · Cited by 350 · see citing works
Randomized Controlled Trial of Cognitive Behavioral Therapy vs Standard Treatment to Prevent Recurrent Cardiovascular Events in Patients With Coronary Heart Disease: Secondary Prevention in Uppsala Primary Health Care Project (SUPRIM)
Gulliksson, M., Burell, G., Vessby, B., Lundin, L., Toss, H., & Svärdsudd, K. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.510 · Cited by 349 · see citing works
Telephone-Delivered Collaborative Care for Treating Post-CABG Depression: A Randomized Controlled Trial
Rollman, B. L., Belnap, B. H., LeMenager, M. S., Mazumdar, S., Houck, P. R., Counihan, P. J., Kapoor, W. N., Schulberg, H. C., & Reynolds, C. F. (2009) · JAMA · doi:10.1001/jama.2009.1670 · Cited by 343 · see citing works
Work-Related Psychosocial Factors and the Development of Ischemic Heart Disease: A Systematic Review
Eller, N. H., Netterstrøm, B., Gyntelberg, F., Kristensen, T. S., Nielsen, F., Steptoe, A., & Theorell, T. (2009) · Cardiology in Review · doi:10.1097/crd.0b013e318198c8e9 · Cited by 323 · see citing works
The Effect of Lifestyle Modification and Cardiovascular Risk Factor Reduction on Erectile Dysfunction: A Systematic Review and Meta-analysis
Gupta, B. P. (2011) · Archives of Internal Medicine · doi:10.1001/archinternmed.2011.440 · Cited by 312 · see citing works
Inequalities in the prevalence of smoking in the European Union: comparing education and income
HUISMAN, M., KUNST, A., & MACKENBACH, J. (2005) · Preventive Medicine · doi:10.1016/j.ypmed.2004.09.022 · Cited by 307 · see citing works
C-Reactive Protein and Reclassification of Cardiovascular Risk in the Framingham Heart Study
Wilson, P. W. F., Pencina, M., Jacques, P., Selhub, J., D'Agostino, R., & O'Donnell, C. J. (2008) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.108.831198 · Cited by 299 · see citing works
Depression and late mortality after myocardial infarction in the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study
Carney, R. M., Blumenthal, J. A., Freedland, K. E., Youngblood, M., Veith, R. C., Burg, M. M., Cornell, C., Saab, P. G., Kaufmann, P. G., Czajkowski, S. M., et al. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000133362.75075.a6 · Cited by 291 · see citing works
Risk of serious adverse cardiovascular events associated with varenicline: a systematic review and meta-analysis
Singh, S., Loke, Y. K., Spangler, J. G., & Furberg, C. D. (2011) · Canadian Medical Association Journal · doi:10.1503/cmaj.110218 · Cited by 286 · see citing works
Psychological treatment of cardiac patients: a meta-analysis
Linden, W., Phillips, M. J., & Leclerc, J. (2007) · European Heart Journal · doi:10.1093/eurheartj/ehm504 · Cited by 284 · see citing works
A General Propensity to Psychological Distress Affects Cardiovascular Outcomes: Evidence From Research on the Type D (Distressed) Personality Profile
Denollet, J., Schiffer, A. A., & Spek, V. (2010) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.109.934406 · Cited by 282 · see citing works
Intensive smoking cessation intervention reduces mortality in high-risk smokers with cardiovascular disease
Mohiuddin, S. M., Mooss, A. N., Hunter, C. B., Grollmes, T. L., Cloutier, D. A., & Hilleman, D. E. (2007) · Chest · doi:10.1378/chest.06-1587 · Cited by 281 · see citing works
Prognostic value of coronary computed tomographic angiography for prediction of cardiac events in patients with suspected coronary artery disease
Hadamitzky, M., Freißmuth, B., Meyer, T., Hein, F., Kastrati, A., Martinoff, S., Schömig, A., & Hausleiter, J. (2009) · JACC: Cardiovascular Imaging · doi:10.1016/j.jcmg.2008.11.015 · Cited by 280 · see citing works
Stress Reduction Prolongs Life in Women With Coronary Disease: The Stockholm Women’s Intervention Trial for Coronary Heart Disease (SWITCHD)
Orth-Gomér, K., Schneiderman, N., Wang, H.-X., Walldin, C., Blom, M., & Jernberg, T. (2009) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.108.812859 · Cited by 266 · see citing works
Effect of home testing of international normalized ratio on clinical events
Matchar, D. B., Jacobson, A., Dolor, R., Edson, R., Uyeda, L., Phibbs, C. S., Vertrees, J. E., Shih, M.-C., Holodniy, M., & Lavori, P. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1002617 · Cited by 266 · see citing works
Impact of traditional and novel risk factors on the relationship between socioeconomic status and incident cardiovascular events
Albert, M. A., Glynn, R. J., Buring, J., & Ridker, P. M. (2006) · Circulation · doi:10.1161/circulationaha.106.660043 · Cited by 262 · see citing works
Associations between apolipoprotein B, apolipoprotein AI, the apolipoprotein B/AI ratio and coronary heart disease: a literature-based meta-analysis of prospective studies
THOMPSON, A., & DANESH, J. (2006) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2006.01644.x · Cited by 252 · see citing works
HDL cholesterol protects against cardiovascular disease in both genders, at all ages and at all levels of risk
Cooney, M. T., Dudina, A., De Bacquer, D., Wilhelmsen, L., Sans, S., Menotti, A., De Backer, G., Jousilahti, P., Keil, U., Thomsen, T., et al. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.02.041 · Cited by 250 · see citing works
Marital status, marital strain, and risk of coronary heart disease or total mortality: the Framingham Offspring Study.
Eaker, E. D., Sullivan, L. M., Kelly-Hayes, M., D’Agostino, R. B., & Benjamin, E. J. (2007) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3180f62357 · Cited by 244 · see citing works
Social Support and Its Relationship to Morbidity and Mortality After Acute Myocardial Infarction: Systematic Overview
Mookadam, F., & Arthur, H. M. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.14.1514 · Cited by 243 · see citing works
EUROASPIRE III. Management of cardiovascular risk factors in asymptomatic high-risk patients in general practice: cross-sectional survey in 12 European countries
Kotseva, K., Wood, D., De Backer, G., De Bacquer, D., Pyörälä, K., Reiner, Ž., Keil, U., & EUROASPIRE Study Group (2010) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3283383f30 · Cited by 238 · see citing works
Chronic inflammation and coronary microvascular dysfunction in patients without risk factors for coronary artery disease
Recio-Mayoral, A., Mason, J. C., Kaski, J. C., Rubens, M. B., Harari, O. A., & Camici, P. G. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp205 · Cited by 235 · see citing works
Mortality from cardiovascular disease more than 10 years after radiotherapy for breast cancer: nationwide cohort study of 90 000 Swedish women
Darby, S., McGale, P., Peto, R., Granath, F., Hall, P., & Ekbom, A. (2003) · BMJ · doi:10.1136/bmj.326.7383.256 · Cited by 235 · see citing works
Placebo-controlled trial of cytisine for smoking cessation
West, R., Zatonski, W., Cedzynska, M., Lewandowska, D., Pazik, J., Aveyard, P., & Stapleton, J. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1102035 · Cited by 234 · see citing works
Treatment of Depression After Coronary Artery Bypass Surgery: A Randomized Controlled Trial
Freedland, K. E., Skala, J. A., Carney, R. M., Rubin, E. H., Lustman, P. J., Dávila-Román, V. G., Steinmeyer, B. C., & Hogue, C. W. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.7 · Cited by 228 · see citing works
Financial barriers to health care and outcomes after acute myocardial infarction
Rahimi, A. R., Spertus, J. A., Reid, K. J., Bernheim, S. M., & Krumholz, H. M. (2007) · JAMA · doi:10.1001/jama.297.10.1063 · Cited by 223 · see citing works
Use of smokeless tobacco and risk of myocardial infarction and stroke: systematic review with meta-analysis
Boffetta, P., & Straif, K. (2009) · BMJ · doi:10.1136/bmj.b3060 · Cited by 222 · see citing works
A decrease in diastolic blood pressure combined with an increase in systolic blood pressure is associated with a higher cardiovascular mortality in men
Benetos, A., Zureik, M., Morcet, J., Thomas, F., Bean, K., Safar, M., Ducimetière, P., & Guize, L. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(99)00586-0 · Cited by 207 · see citing works
Panic Attacks and Risk of Incident Cardiovascular Events Among Postmenopausal Women in the Women's Health Initiative Observational Study
Smoller, J. W., Pollack, M. H., Wassertheil-Smoller, S., Jackson, R. D., Oberman, A., Wong, N. D., & Sheps, D. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.10.1153 · Cited by 204 · see citing works
Beneficial effects of potassium
He, F. J., & MacGregor, G. A. (2001) · BMJ · doi:10.1136/bmj.323.7311.497 · Cited by 201 · see citing works
Impact of a prescription copayment increase on lipid-lowering medication adherence in veterans
Doshi, J. A., Zhu, J., Lee, B. Y., Kimmel, S. E., & Volpp, K. G. (2009) · Circulation · doi:10.1161/circulationaha.108.783944 · Cited by 184 · see citing works
Anxiety worsens prognosis in patients with coronary artery disease
Shibeshi, W. A., Young-Xu, Y., & Blatt, C. M. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.03.007 · Cited by 182 · see citing works
Treatment of Obstructive Sleep Apnea Is Associated With Decreased Cardiac Death After Percutaneous Coronary Intervention
Cassar, A., Morgenthaler, T. I., Lennon, R. J., Rihal, C. S., & Lerman, A. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.06.028 · Cited by 177 · see citing works
Relation of heart rate at rest and long-term (>20 years) death rate in initially healthy middle-aged men
Jouven, X., Empana, J. P., Escolano, S., Buyck, J. F., Tafflet, M., Desnos, M., & Ducimetière, P. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.08.071 · Cited by 175 · see citing works
Meta-analysis of disease risk associated with smoking, by gender and intensity of smoking
Mucha, L., Stephenson, J., Morandi, N., & Dirani, R. (2006) · Gender Medicine · doi:10.1016/s1550-8579(06)80216-0 · Cited by 169 · see citing works
Barriers to apply cardiovascular prediction rules in primary care: a postal survey
Eichler, K., Zoller, M., Tschudi, P., & Steurer, J. (2007) · BMC Family Practice · doi:10.1186/1471-2296-8-1 · Cited by 167 · see citing works
Employee effects of an educational program for managers at an insurance company
Theorell, T., Emdad, R., Arnetz, B., & Weingarten, A.-M. (2001) · Psychosomatic Medicine · doi:10.1097/00006842-200109000-00004 · Cited by 164 · see citing works
Association between lipoprotein-associated phospholipase A2 and cardiovascular disease: a systematic review
Garza, C. A., Montori, V. M., McConnell, J. P., Somers, V. K., Kullo, I. J., & Lopez-Jimenez, F. (2007) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)60992-0 · Cited by 159 · see citing works
Importance of light smoking and inhalation habits on risk of myocardial infarction and all cause mortality. A 22 year follow up of 12 149 men and women in The Copenhagen City Heart Study
Prescott, E., Scharling, H., Osler, M., & Schnohr, P. (2002) · Journal of Epidemiology and Community Health · doi:10.1136/jech.56.9.702 · Cited by 154 · see citing works
Does erectile dysfunction contribute to cardiovascular disease risk prediction beyond the Framingham risk score?
Araujo, A. B., Hall, S. A., Ganz, P., Chiu, G. R., Rosen, R. C., Kupelian, V., Travison, T. G., & McKinlay, J. B. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.08.058 · Cited by 153 · see citing works
Rapid mortality falls after risk-factor changes in populations
Capewell, S., & O'Flaherty, M. (2011) · The Lancet · doi:10.1016/s0140-6736(10)62302-1 · Cited by 149 · see citing works
Coronary calcification detected by electron-beam computed tomography and myocardial infarction. The Rotterdam Coronary Calcification Study
Vliegenthart, R. (2002) · European Heart Journal · doi:10.1053/euhj.2002.3240 · Cited by 144 · see citing works
The short-term effects of a hostility-reduction intervention on male coronary heart disease patients
Gidron, Y., Davidson, K., & Bata, I. (1999) · Health Psychology · doi:10.1037/0278-6133.18.4.416 · Cited by 136 · see citing works
Reliability of anthropometric measurements in overweight and lean subjects: consequences for correlations between anthropometric and other variables
Nordhamn, K., Södergren, E., Olsson, E., Karlström, B., Vessby, B., & Berglund, L. (2000) · International Journal of Obesity · doi:10.1038/sj.ijo.0801216 · Cited by 131 · see citing works
Coronary atherosclerosis in unheralded sudden coronary death under age 50: histo-pathologic comparison with ‘healthy’ subjects dying out of hospital
Schmermund, A., Schwartz, R. S., Adamzik, M., Sangiorgi, G., Pfeifer, E. A., Rumberger, J. A., Burke, A. P., Farb, A., & Virmani, R. (2001) · Atherosclerosis · doi:10.1016/s0021-9150(00)00598-0 · Cited by 130 · see citing works
Two years after molecular diagnosis of familial hypercholesterolemia: majority on cholesterol-lowering treatment but a minority reaches treatment goal
Huijgen, R., Kindt, I., Verhoeven, S. B. J., Sijbrands, E. J. G., Vissers, M. N., Kastelein, J. J. P., & Hutten, B. A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009220 · Cited by 124 · see citing works
Long-term survival after acute myocardial infarction is lower in more deprived neighborhoods
Tonne, C., Schwartz, J., Mittleman, M., Melly, S., Suh, H., & Goldberg, R. (2005) · Circulation · doi:10.1161/circulationaha.104.496174 · Cited by 122 · see citing works
Changes in leisure time physical activity and risk of all-cause mortality in men and women: the Baltimore Longitudinal Study of Aging
Talbot, L. A., Morrell, C. H., Fleg, J. L., & Metter, E. J. (2007) · Preventive Medicine · doi:10.1016/j.ypmed.2007.05.014 · Cited by 121 · see citing works
The effect of optimal medical therapy on 1-year mortality after acute myocardial infarction
Bramlage, P., Messer, C., Bitterlich, N., Pohlmann, C., Cuneo, A., Stammwitz, E., Tebbenjohanns, J., Gohlke, H., Senges, J., & Tebbe, U. (2010) · Heart · doi:10.1136/hrt.2009.188607 · Cited by 115 · see citing works
Fasting versus nonfasting triglycerides and the prediction of cardiovascular risk: do we need to revisit the oral triglyceride tolerance test?
Ridker, P. M. (2008) · Clinical Chemistry · doi:10.1373/clinchem.2007.097907 · Cited by 114 · see citing works
Effectiveness of nurse-delivered cardiovascular risk management in primary care: a randomised trial
Voogdt-Pruis, H. R., Beusmans, G. H., Gorgels, A. P., Kester, A. D., & Van Ree, J. W. (2010) · British Journal of General Practice · doi:10.3399/bjgp10x482095 · Cited by 114 · see citing works
Integrated electronic decision support increases cardiovascular disease risk assessment four fold in routine primary care practice
Wells, S., Furness, S., Rafter, N., Horn, E., Whittaker, R., Stewart, A., Moodabe, K., Roseman, P., Selak, V., Bramley, D., et al. (2008) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3282f13af4 · Cited by 109 · see citing works
Reliability of doctors' anthropometric measurements to detect obesity
Sebo, P., Beer-Borst, S., Haller, D. M., & Bovier, P. A. (2008) · Preventive Medicine · doi:10.1016/j.ypmed.2008.06.012 · Cited by 108 · see citing works
Left ventricular hypertrophy and cardiovascular mortality by race and ethnicity
Havranek, E. P., Froshaug, D. B., Emserman, C. D. B., Hanratty, R., Krantz, M. J., Masoudi, F. A., Dickinson, L. M., & Steiner, J. F. (2008) · The American Journal of Medicine · doi:10.1016/j.amjmed.2008.05.034 · Cited by 107 · see citing works
Improving lifestyle and risk perception through patient involvement in nurse-led cardiovascular risk management: a cluster-randomized controlled trial in primary care
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Effects of a home-based intervention program on anxiety and depression 6 months after coronary artery bypass grafting: a randomized controlled trial
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Noninvasive coronary angiography—an acceptable alternative?
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Ludvig, J., Miner, B., & Eisenberg, M. J. (2005) · American Heart Journal · doi:10.1016/j.ahj.2004.09.040 · Cited by 87 · see citing works
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Vos, L. (2003) · American Journal of Hypertension · doi:10.1016/s0895-7061(03)00857-4 · Cited by 85 · see citing works
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5-year results of a comprehensive rehabilitation programme after myocardial infarction
HEDBÃCK, B., & PERK, J. (1987) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a062265 · Cited by 83 · see citing works
Self-citation
Secondary Prevention After Coronary Artery Bypass Graft Surgery: Findings of a National Randomized Controlled Trial and Sustained Society-Led Incorporation Into Practice
Williams, J. B., DeLong, E. R., Peterson, E. D., Dokholyan, R. S., Ou, F.-S., & Ferguson, T. B. (2011) · Circulation · doi:10.1161/circulationaha.110.981068 · Cited by 79 · see citing works
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Weber, C., Erl, W., & Weber, P. C. (1995) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1995.1088 · Cited by 78 · see citing works
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Chen, Y.-H., Tsai, S.-Y., Lee, H.-C., & Lin, H.-C. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181ad55e3 · Cited by 71 · see citing works
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Yamaguchi, Y., Matsuno, S., Kagota, S., Haginaka, J., & Kunitomo, M. (2001) · Atherosclerosis · doi:10.1016/s0021-9150(00)00637-7 · Cited by 69 · see citing works
Volumetric intravascular ultrasound quantification of the amount of atherosclerosis and calcium in nonstenotic arterial segments
Tinana, A., Mintz, G. S., & Weissman, N. J. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(01)02349-9 · Cited by 57 · see citing works
Coronary age as a risk factor in the modified Framingham risk score
Schisterman, E. F., & Whitcomb, B. W. (2004) · BMC Medical Imaging · doi:10.1186/1471-2342-4-1 · Cited by 47 · see citing works
Evaluation of the American Heart Association cardiovascular disease prevention guideline for women
Hsia, J., Rodabough, R. J., Manson, J. E., Liu, S., Freiberg, M. S., Graettinger, W., Rosal, M. C., Cochrane, B., Lloyd-Jones, D., Robinson, J. G., et al. (2010) · Circulation: Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.108.842385 · Cited by 45 · see citing works
Atenolol as initial antihypertensive therapy: an observational study comparing first-line agents
Blackburn, D. F., Lamb, D. A., Eurich, D. T., Johnson, J. A., Wilson, T. W., Dobson, R. T., & Blackburn, J. L. (2007) · Journal of Hypertension · doi:10.1097/hjh.0b013e328136bd21 · Cited by 39 · see citing works
The double jeopardy of clustered measurement and cluster randomisation
Kramer, M. S., Martin, R. M., Sterne, J. A. C., Shapiro, S., Dahhou, M., & Platt, R. W. (2009) · BMJ · doi:10.1136/bmj.b2900 · Cited by 32 · see citing works
Comparison of coronary imaging between magnetic resonance imaging and electron beam computed tomography
van Geuns, R.-J. M., Oudkerk, M., Rensing, B. J. W. M., Bongaerts, A. H. H., de Bruin, H. G., Wielopolski, P. A., van Ooijen, P., de Feyter, P. J., & Serruys, P. W. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02389-5 · Cited by 24 · see citing works
Marital Stress Worsens Prognosis in Women With Coronary Heart Disease: The Stockholm Female Coronary Risk Study
Orth-Gomér, K., Wamala, S. P., Horsten, M., Schenck-Gustafsson, K., Schneiderman, N., & Mittleman, M. A. (2000) · JAMA · doi:10.1001/jama.284.23.3008 · Cited by 6 · see citing works

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Authors: Authors/Task Force Members: Joep Perk (Chairperson) (Sweden)*, G. D. B. (.
Venue: European Journal of Preventive Cardiology
Publisher: Oxford University Press (OUP)
Published: 2012-07-04
Volume: 19
Issue: 4
Pages: 585-667
ISSN: 2047-4873 (ISSN-L)
2047-4881
DOI: 10.1177/2047487312450228
OpenAlex: W1510658613
Cited by: 863
References: 178
Citations by year: 2026: 3 · 2025: 10 · 2024: 16 · 2023: 24 · 2022: 23 · 2021: 26 · 2020: 29 · 2019: 64 · 2018: 45 · 2017: 68 · 2016: 93 · 2015: 114 · 2014: 111 · 2013: 81 · 2012: 58
FWCI: 112.40
Type: journal article
Language: en
Open access: closed
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: European Journal of Preventive Cardiology (publishedVersion)
PubMed (publishedVersion)
LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
Ghent University Academic Bibliography (Ghent University) (submittedVersion)
Open Repository and Bibliography (University of Liège) (submittedVersion)
Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords: cardiovascular disease prevention, primary prevention, secondary prevention, cardiovascular risk factors, cardiovascular risk assessment, lifestyle modification, cardiovascular risk management
MeSH terms: Cardiology, Cardiovascular Diseases, Europe, Humans, Preventive Health Services, Risk Factors, Comorbidity, Risk Assessment, Patient Selection, Evidence-Based Medicine

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