Cited by 54,751Lipid metabolism and biosynthesisEdible Oils Quality and AnalysisFood Nutrient Composition and Product Development

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Bligh, E. G., Dyer, W. J.·1959·Canadian Journal of Biochemistry and Physiology

DOI 10.1139/o59-099

Open this paper in CoChat — free account

Abstract

Lipid decomposition studies in frozen fish have led to the development of a simple and rapid method for the extraction and purification of lipids from biological materials. The entire procedure can be carried out in approximately 10 minutes; it is efficient, reproducible, and free from deleterious manipulations. The wet tissue is homogenized with a mixture of chloroform and methanol in such proportions that a miscible system is formed with the water in the tissue. Dilution with chloroform and water separates the homogenate into two layers, the chloroform layer containing all the lipids and the methanolic layer containing all the non-lipids. A purified lipid extract is obtained merely by isolating the chloroform layer. The method has been applied to fish muscle and may easily be adapted to use with other tissues.

Integrity signals

Registry

Crossref · 10.1139/o59-099

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES
Folch, J., Lees, M., & Stanley, G. H. S. (1957) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)64849-5 · Cited by 65,189
PREPARATION OF LIPIDE EXTRACTS FROM BRAIN TISSUE
Folch, J., Ascoli, I., Lees, M. B., Meath, J. A., & Lebaron, F. N. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55987-1 · Cited by 1,341
Storage of Frozen Plaice Fillets
Dyer, W. J., & Morton, M. L. (1956) · Journal of the Fisheries Research Board of Canada · doi:10.1139/f56-007 · Cited by 69
Self-citation
Experimental Determination of Binodal Curves, Plait Points, and Tie Lines, in 50 Systems, each consisting of Water and Two Organic Liquids
Bonner, W. D. (1910) · The Journal of Physical Chemistry · doi:10.1021/j150116a004 · Cited by 46
Acetone–Water Mixtures for the Extraction and Rapid Estimation of Fats of Biological Materials, Particularly Fish Products
Dambergs, N. (1956) · Journal of the Fisheries Research Board of Canada · doi:10.1139/f56-045 · Cited by 18

Show all 5 references

Research works printed but not linked: 1

BANCROFT W., 1895, Phys. Iiev., 3, 1

Sorted by citations

Items 1,901–2,000 of 48,847

Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation
Vidal, M., Mangeat, P. H., & Hoekstra, D. (1997) · Journal of Cell Science · doi:10.1242/jcs.110.16.1867 · Cited by 184
Microbial community composition and function beneath temperate trees exposed to elevated atmospheric carbon dioxide and ozone
Phillips, R., Zak, D. R., Holmes, W. E., & White, D. C. (2002) · Oecologia · doi:10.1007/s00442-002-0868-x · Cited by 184
Effect of Dietary Lipids and Vitamin E on in Vitro Lipid Peroxidation in Rat Liver and Kidney Homogenates
Hu, M., Frankel, E. N., Leibovitz, B. E., et al. (1989) · Journal of Nutrition · doi:10.1093/jn/119.11.1574 · Cited by 186
Tumor necrosis factor induces rapid production of 1'2'diacylglycerol by a phosphatidylcholine-specific phospholipase C.
Schütze, S., Berkovic, D., Tomsing, O., Unger, C., & Krönke, M. (1991) · The Journal of Experimental Medicine · doi:10.1084/jem.174.5.975 · Cited by 183
The effect of alterations in fatty acid composition and cholesterol content on the nonelectrolyte permeability of Acholeplasma laidlawii B cells and derived liposomes
McElhaney, R. N., de Gier, J., & Neut-Kok, E. C. M. V. D. (1973) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(73)90376-3 · Cited by 186
Vitamin D3-25-hydroxylase: Tissue occurrence and apparent lack of regulation
Tucker, G. F., Gagnon, R. E., & Haussler, M. R. (1973) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(73)80008-6 · Cited by 186
Some studies on the metabolism of phospholipids in Golgi complex from bovine and rat liver in comparison to other subcellular fractions
GOLDE, L. M. G. V., Fleischer, B., & Fleischer, S. (1971) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(71)90109-x · Cited by 186
Biosynthesis of N-glycosidically linked glycoproteins during gastrulation of sea urchin embryos.
Heifetz, A. H., & Lennarz, W. J. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)50527-5 · Cited by 186
Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis
Perry, R. J., Zhang, D., Guerra, M. T., Brill, A. L., Goedeke, L., Nasiri, A. R., Rabin-Court, A., Wang, Y., Peng, L., Dufour, S., et al. (2020) · Nature · doi:10.1038/s41586-020-2074-6 · Cited by 186
“…R2=0.999 and 0.999), long-chain CoA 31 , DAG 31 , and ceramide 31 concentrations were measured by LC-MS/MS, hepatic glycogen content following amyloglucosidase digestion 32 , and TAG concentrations enzymatically 33 . cAMP concentrations were measured using the Enzo Life Sciences Direct cAMP ELISA.”
Influential
Fat-soluble vitamin contents and fatty acid composition in organic and conventional Italian dairy products
Bergamo, P. (2003) · Food Chemistry · doi:10.1016/s0308-8146(03)00036-0 · Cited by 185
Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance
Choi, C. S., Fillmore, J. J., Kim, J. K., Liu, Z., Kim, S., Collier, E. F., Kulkarni, A. S., Distefano, A. G., Hwang, Y.-J., Kahn, M., et al. (2007) · Journal of Clinical Investigation · doi:10.1172/jci13579 · Cited by 183
Effects of acclimation temperature on thermal tolerance and membrane phospholipid composition in the fruit fly Drosophila melanogaster
Overgaard, J., Tomčala, A., Sørensen, J. G., Holmstrup, M., Krogh, P. H., Šimek, P., & Košťál, V. (2008) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2007.12.011 · Cited by 185
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate–containing RGD peptide liposomes inhibits experimental arthritis
Koning, G. A., Schiffelers, R. M., Wauben, M. H. M., et al. (2006) · Arthritis & Rheumatism · doi:10.1002/art.21719 · Cited by 185
Top-Down Lipidomic Screens by Multivariate Analysis of High-Resolution Survey Mass Spectra
Schwudke, D., Hannich, J. T., Surendranath, V., Grimard, V., Moehring, T., Burton, L., Kurzchalia, T. V., & Shevchenko, A. (2007) · Analytical Chemistry · doi:10.1021/ac062455y · Cited by 186
Crenarchaeol dominates the membrane lipids of Candidatus Nitrososphaera gargensis, a thermophilic Group I.1b Archaeon
Pitcher, A., Rychlik, N., Hopmans, E. C., Spieck, E., Rijpstra, W. I. C., Ossebaar, J., Schouten, S., Wagner, M., & Damsté, J. S. S. (2009) · The ISME Journal · doi:10.1038/ismej.2009.138 · Cited by 198
Flaxseed oil – Whey protein isolate emulsions: Effect of high pressure homogenization
Kuhn, K. R., & Cunha, R. L. (2012) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2012.01.016 · Cited by 186
Influence of emulsified olive oil stabilizing system used for pork backfat replacement in frankfurters
Jiménez-Colmenero, F., Herrero, A. M., Pintado, T., Solas, M. T., & Ruíz‐Capillas, C. (2010) · Food Research International · doi:10.1016/j.foodres.2010.06.010 · Cited by 183
Soil microbial community composition as affected by restoration practices in California grassland
Potthoff, M., Steenwerth, K. L., Jackson, L. E., Drenovsky, R. E., Scow, K. M., & Joergensen, R. G. (2006) · Soil Biology and Biochemistry · doi:10.1016/j.soilbio.2005.12.009 · Cited by 185
The impacts of individual plant species on rhizosphere microbial communities in soils of different fertility
Innes, L., Hobbs, P. J., & Bardgett, R. D. (2004) · Biology and Fertility of Soils · doi:10.1007/s00374-004-0748-0 · Cited by 185
Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples
Han, X., Yang, K., Yang, J., Cheng, H., & Gross, R. W. (2006) · Journal of Lipid Research · doi:10.1194/jlr.d500044-jlr200 · Cited by 190
Alkaliphilus transvaalensis gen. nov., sp. nov., an extremely alkaliphilic bacterium isolated from a deep South African gold mine.
Takai, K., Moser, D. P., Onstott, T. C., Spoelstra, N., Pfiffner, S. M., Dohnalkova, A. C., & Fredrickson, J. K. (2001) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-51-4-1245 · Cited by 186
Structure of hepatitis B surface antigen. Characterization of the lipid components and their association with the viral proteins.
Gavilanes, F., González-Ros, J. M., & Peterson, D. L. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34448-x · Cited by 185
Role of lipophorin in lipid transport to the insect egg.
Kawooya, J. K., & Law, J. H. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68369-3 · Cited by 184
A comparison of the molecular species compositions of mammalian lung surfactant phospholipids
Postle, A. D., Heeley, E. L., & Wilton, D. C. (2001) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/s1095-6433(01)00306-3 · Cited by 185
Influence of finishing diet on fatty acid profiles of intramuscular lipids, triglycerides and phospholipids in muscles of the Iberian pig
Cava, R., Ruiz, J., López-Bote, C. J., et al. (1997) · Meat Science · doi:10.1016/s0309-1740(96)00102-7 · Cited by 185
Apolipoprotein-mediated Plasma Membrane Microsolubilization
Gillotte, K. L., Zaiou, M., Lund‐Katz, S., Anantharamaiah, G. M., Holvoet, P., Dhoest, A., Palgunachari, M. N., Segrest, J. P., Weisgraber, K. H., Rothblat, G. H., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.4.2021 · Cited by 183
The Regulation of Rat Liver Calciferol-25-hydroxylase
Bhattacharyya, M. H., & DeLuca, H. F. (1973) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)43995-1 · Cited by 185
Metabolism of vitamin D. A new cholecalciferol metabolite, involving loss of hydrogen at C-1, in chick intestinal nuclei
Lawson, D. E. M., Wilson, P. W., & Kodicek, E. H. (1969) · Biochemical Journal · doi:10.1042/bj1150269 · Cited by 185
Mechanism of cholesterol efflux from cells. Effects of acceptor structure and concentration.
Rothblat, G. H., & Phillips, M. C. (1982) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)34593-9 · Cited by 185
The effect of alterations in the physical state of the membrane lipids on the ability of Acholeplasma laidlawii B to grow at various temperatures
McElhaney, R. N. (1974) · Journal of Molecular Biology · doi:10.1016/0022-2836(74)90218-6 · Cited by 185
Components of the mitochondrial inner membrane. 5. Interaction of detergents with cytochrome c oxidase
Robinson, N. C., & Capaldi, R. (1977) · Biochemistry · doi:10.1021/bi00622a006 · Cited by 185
The effect of dietary fat on the molecular species of lecithin from rat liver
GOLDE, L. M. G. V., & Deenen, L. L. M. V. (1966) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(66)90038-5 · Cited by 185
Chemical biomarkers in aquatic ecosystems
Bianchi, T. S., & Canuel, E. A. (2011) · Choice Reviews Online · doi:10.5860/choice.49-0862 · Cited by 186
Evaluation of methods to extract and quantify lipids from Synechocystis PCC 6803
Sheng, J., Vannela, R., & Rittmann, B. E. (2011) · Bioresource Technology · doi:10.1016/j.biortech.2010.08.007 · Cited by 184
Estimation of fungal biomass in forest litter and soil
Baldrián, P., Větrovský, T., Cajthaml, T., et al. (2012) · Fungal ecology · doi:10.1016/j.funeco.2012.10.002 · Cited by 184
Microwave, ultrasound, thermal treatments, and bead milling as intensification techniques for extraction of lipids from oleaginous Yarrowia lipolytica yeast for a biojetfuel application
Meullemiestre, A., Breil, C., Vian, M. A., & Chemat, F. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.03.040 · Cited by 185
Differences in Metabolism between the Biofilm and Planktonic Response to Metal Stress
Booth, S. C., Workentine, M. L., Wen, J., Shaykhutdinov, R. A., Vogel, H. J., Ceri, H., Turner, R. J., & Weljie, A. M. (2011) · Journal of Proteome Research · doi:10.1021/pr2002353 · Cited by 183
Antioxidant activity of pomegranate peel extract on lipid and protein oxidation in beef meatballs during frozen storage
Turgut, S. S., Işıkçı, F., & Soyer, A. (2017) · Meat Science · doi:10.1016/j.meatsci.2017.02.019 · Cited by 184
Impaired β-Oxidation and Altered Complex Lipid Fatty Acid Partitioning with Advancing CKD
Afshinnia, F., Rajendiran, T. M., Soni, T., Byun, J., Wernisch, S., Sas, K. M., Hawkins, J. J., Bellovich, K. A., Gipson, D., Michailidis, G. C., et al. (2017) · Journal of the American Society of Nephrology · doi:10.1681/asn.2017030350 · Cited by 190
The Impact of Using Microalgae as Biofertilizer in Maize (Zea mays L.)
Dineshkumar, R., Subramanian, J., Gopalsamy, J., Jayasingam, P., Arumugam, A., Kannadasan, S., & Sampathkumar, P. (2017) · Waste and Biomass Valorization · doi:10.1007/s12649-017-0123-7 · Cited by 185
Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction
Devequi-Nunes, D., Machado, B. A. S., Barreto, G. D. A., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207676 · Cited by 184
Extraction, Characterization, and Cellular Localization of the Lipids of Staphylococcus aureus
White, D. C. S., & Frerman, F. E. (1967) · Journal of Bacteriology · doi:10.1128/jb.94.6.1854-1867.1967 · Cited by 184
Oyster Preservation by High-Pressure Treatment
López-Caballero, M. E., Pérez-Mateos, M., Montero, P., et al. (2000) · Journal of Food Protection · doi:10.4315/0362-028x-63.2.196 · Cited by 184
Carbon Isotopic Evidence for Different Feeding Patterns in Two Hyrax Species Occupying the Same Habitat
DeNiro, M. J., & Epstein, S. (1978) · Science · doi:10.1126/science.201.4359.906 · Cited by 184
Temperature-Induced Changes in the Fatty Acid Composition of the Cyanobacterium, Synechocystis PCC6803
Wada, H., & Murata, N. (1990) · PLANT PHYSIOLOGY · doi:10.1104/pp.92.4.1062 · Cited by 188
Thiazolidinedione compounds ameliorate glomerular dysfunction independent of their insulin-sensitizing action in diabetic rats.
Isshiki, K., Haneda, M., Koya, D., et al. (2000) · Diabetes · doi:10.2337/diabetes.49.6.1022 · Cited by 184
The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG‐A, PIG‐H, PIG‐C and GPI1
Watanabe, R., Inoue, N., Westfall, B. A., Taron, C. H., Orlean, P., Takeda, J., & Kinoshita, T. (1998) · The EMBO Journal · doi:10.1093/emboj/17.4.877 · Cited by 183
Effects of Aspirin on Platelet-Neutrophil Interactions
López-Farré, A. J., Caramelo, C. A., Esteban, A., Alberola, M. L., Millás, I., Montón, M., & Casado, S. (1995) · Circulation · doi:10.1161/01.cir.91.7.2080 · Cited by 183
Role of Cholesterol in Formation and Function of a Signaling Complex Involving αvβ3, Integrin-Associated Protein (Cd47), and Heterotrimeric G Proteins
Green, J. M., Zheleznyak, A., Chung, J., Lindberg, F. P., Sarfati, M., Frazier, W. A., & Brown, E. J. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.3.673 · Cited by 184
The bidirectional flux of cholesterol between cells and lipoproteins. Effects of phospholipid depletion of high density lipoprotein.
Johnson, W. J., Bamberger, M. J., Latta, R. A., et al. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)38448-x · Cited by 184
Receptor-mediated net breakdown of phosphatidylinositol 4,5-bisphosphate in parotid acinar cells
Weiss, S. J., McKinney, J. S., & Putney, J. W. (1982) · Biochemical Journal · doi:10.1042/bj2060555 · Cited by 184
Evaluation of fuel properties for microalgae Spirulina platensis bio-diesel and its blends with Egyptian petro-diesel
Mostafa, S. S. M., & El‐Gendy, N. S. (2013) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2013.07.034 · Cited by 182
Identification of 9-Hydroxyoctadecadienoic Acid and Other Oxidized Free Fatty Acids as Ligands of the G Protein-coupled Receptor G2A
Obinata, H., Hattori, T., Nakane, S., Tatei, K., & Izumi, T. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507787200 · Cited by 185
Enhancement of extraplastidic oil synthesis in C hlamydomonas reinhardtii using a type‐2 diacylglycerol acyltransferase with a phosphorus starvation–inducible promoter
Iwai, M., Ikeda, K., Shimojima, M., & Ohta, H. (2014) · Plant Biotechnology Journal · doi:10.1111/pbi.12210 · Cited by 182
Rab-regulated interaction of early endosomes with lipid droplets
Liu, P., Bartz, R., Zehmer, J. K., Ying, Y., Zhu, M., Serrero, G., & Anderson, R. G. W. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2007.02.004 · Cited by 182
Molecular Analysis of a Bifunctional Fatty Acid Conjugase/Desaturase from Tung. Implications for the Evolution of Plant Fatty Acid Diversity
Dyer, J. M., Chapital, D. C., Kuan, J. W., et al. (2002) · PLANT PHYSIOLOGY · doi:10.1104/pp.102.010835 · Cited by 183
Detrimental effects of recent ocean surface warming on growth condition of Atlantic salmon
TODD, C. D., Hughes, S. L., Marshall, C. T., MacLean, J. C., LONERGAN, M. E., & Biuw, M. (2007) · Global Change Biology · doi:10.1111/j.1365-2486.2007.01522.x · Cited by 182
Durum Wheat Lipoxygenase Activity and Other Quality Parameters that Affect Pasta Color
Borrelli, G. M., Troccoli, A., di Fonzo, N., et al. (1999) · Cereal Chemistry · doi:10.1094/cchem.1999.76.3.335 · Cited by 183
Biological and physicochemical properties of biosurfactants produced by Lactobacillus jensenii P6A and Lactobacillus gasseri P65
Morais, I. M. C., Cordeiro, A. L. S., Teixeira, G. S., Domingues, V. S., Nardi, R. M. D., Monteiro, A. S., Alves, R. J., de Siqueira, E. P., & dos Santos, V. L. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0769-7 · Cited by 182
Lipidomic profiling of human serum enables detection of pancreatic cancer
Wolrab, D., Jirásko, R., Cífková, E., Höring, M., Ding, M., Chocholoušková, M., Peterka, O., Idkowiak, J., Hrnčiarová, T., Kuchař, L., et al. (2022) · Nature Communications · doi:10.1038/s41467-021-27765-9 · Cited by 192
Microbial and Meiofaunal Response to Intensive Mussel-Farm Biodeposition in Coastal Sediments of the Western Mediterranean
Mirto, S., Rosa, T. L., Danovaro, R., et al. (2000) · Marine Pollution Bulletin · doi:10.1016/s0025-326x(99)00209-x · Cited by 183
Effect of extrusion processing and steam pelleting diets on pellet durability, pellet water absorption, and the physiological response of rainbow trout (Salmo gairdneri R.)
Hilton, J. W., Cho, C. Y., & Slinger, S. J. (1981) · Aquaculture · doi:10.1016/0044-8486(81)90180-0 · Cited by 183
Oxidation of unsaturated phospholipids in membrane bilayer mixtures is accompanied by membrane fluidity changes
Borst, J. W., Visser, N. V., Kouptsova, O., et al. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(00)00084-6 · Cited by 183
Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo
Borron, P. J., McIntosh, J. C., Korfhagen, T. R., et al. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.278.4.l840 · Cited by 183
Pathophysiology of congenital diaphragmatic hernia II: The fetal lamb CDH model is surfactant deficient
Glick, P. L., Stannard, V. A., Leach, C. L., et al. (1992) · Journal of Pediatric Surgery · doi:10.1016/0022-3468(92)90865-5 · Cited by 183
Tight binding inhibitors of 85-kDa phospholipase A2 but not 14-kDa phospholipase A2 inhibit release of free arachidonate in thrombin-stimulated human platelets.
Bártoli, F., Lin, H. K., Ghomashchi, F., Gelb, M. H., Jain, M. K., & Apitz-Castro, R. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)40727-7 · Cited by 182
Characterization of the chromobindins. Soluble proteins that bind to the chromaffin granule membrane in the presence of Ca2+.
Creutz, C. E., Dowling, L. G., Sando, J. J., et al. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)43914-7 · Cited by 183
Lysophosphatidylcholine: Essential role in the inhibition of endothelium-dependent vasorelaxation by oxidized low density lipoprotein
Yokoyama, M., Hirata, K., Miyake, R., et al. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)91708-z · Cited by 183
Orally administered CLA ameliorates DSS-induced colitis in mice via intestinal barrier improvement, oxidative stress reduction, and inflammatory cytokine and gut microbiota modulation
Chen, Y., Yang, B., Ross, R. P., Jin, Y., Stanton, C., Zhao, J., Zhang, H., & Chen, W. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b05744 · Cited by 185
Chickens fed with biomass of the red microalga Porphyridium sp. have reduced blood cholesterol level and modified fatty acid composition in egg yolk
Ginzberg, A., Cohen, M., Sod-Moriah, U. A., Shany, S., Rosenshtrauch, A., & Arad, S. (2000) · Journal of Applied Phycology · doi:10.1023/a:1008102622276 · Cited by 182
Evidence for the reversibility of the acyl-CoA:lysophosphatidylcholine acyltransferase in microsomal preparations from developing safflower ( Carthamus tinctorius L.) cotyledons and rat liver
Stymne, S., & Stobart, A. K. (1984) · Biochemical Journal · doi:10.1042/bj2230305 · Cited by 182
Castor Phospholipid:Diacylglycerol Acyltransferase Facilitates Efficient Metabolism of Hydroxy Fatty Acids in Transgenic Arabidopsis
van Erp, H., Bates, P. D., Burgal, J., et al. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.167239 · Cited by 182
CHEMICALLY MEDIATED COMPETITION BETWEEN MICROBES AND ANIMALS: MICROBES AS CONSUMERS IN FOOD WEBS
Burkepile, D. E., Parker, J. D., Woodson, C. B., Mills, H. J., Kubanek, J., Sobecky, P. A., & Hay, M. E. (2006) · Ecology · doi:10.1890/0012-9658(2006)87[2821:cmcbma]2.0.co;2 · Cited by 181
Altered Pharmacokinetics of 1α,25-Dihydroxyvitamin D3and 25-Hydroxyvitamin D3in the Blood and Tissues of the 25-Hydroxyvitamin D-24-Hydroxylase (Cyp24a1) Null Mouse
増田, 園., Byford, V., Arabian, A., Sakai, Y., Demay, M. B., St‐Arnaud, R., & Jones, G. (2004) · Endocrinology · doi:10.1210/en.2004-1116 · Cited by 182
Potential of using organic fertilizer to cultivate Chlorella vulgaris for biodiesel production
Lam, M. K., & Lee, K. T. (2012) · Applied Energy · doi:10.1016/j.apenergy.2012.01.075 · Cited by 180
Antioxidant capacity and chemical composition in seeds rich in omega-3: chia, flax, and perilla
Sargi, S. C., Silva, B. C. E., dos Santos, H. M. C., Montanher, P. F., Boeing, J. S., Santos, O. O., de Souza, N. E., & Visentainer, J. V. (2013) · Food Science and Technology · doi:10.1590/s0101-20612013005000057 · Cited by 182
Hydrolysis of Monogalactosyl and Digalactosyl Diglycerides by Specific Enzymes in Runner-Bean Leaves*
SASTRY, P. S., & Kates, M. (1964) · Biochemistry · doi:10.1021/bi00897a016 · Cited by 182
Oleic acid is elevated in cell membranes during rapid cold-hardening and pupal diapause in the flesh fly, Sarcophaga crassipalpis
Michaud, M. R., & Denlinger, D. L. (2006) · Journal of Insect Physiology · doi:10.1016/j.jinsphys.2006.07.005 · Cited by 182
Development of fatty acid analysis by high-performance liquid chromatography, gas chromatography, and related techniques
Brondz, I. (2002) · Analytica Chimica Acta · doi:10.1016/s0003-2670(01)01467-2 · Cited by 182
Comparison of the effects of fish and fish-oil capsules on the n–3 fatty acid content of blood cells and plasma phospholipids
Harris, W. S., Pottala, J. V., Sands, S. A., & Jones, P. G. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1621 · Cited by 184
Best practices for the design, laboratory analysis, and reporting of trials involving fatty acids
Brenna, J. T., Plourde, M., Stark, K. D., et al. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy089 · Cited by 182
Mouse P450RAI (CYP26) Expression and Retinoic Acid-inducible Retinoic Acid Metabolism in F9 Cells Are Regulated by Retinoic Acid Receptor γ and Retinoid X Receptor α
Abu–Abed, S., Beckett, B., Chiba, H., Chithalen, J. V., Jones, G., METZGER, D., Chambon, P., & Petkovich, M. P. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.4.2409 · Cited by 181
Tailoring of a cardioprotective muscle fatty acid composition of Atlantic salmon (Salmo salar) fed vegetable oils
Torstensen, B. E., Frøyland, L., Ørnsrud, R., & Lie, Ø. H. (2004) · Food Chemistry · doi:10.1016/j.foodchem.2004.01.009 · Cited by 182
Replacement of herring oil with menhaden oil, soybean oil, or tallow in the diets of Atlantic salmon raised in marine net-pens
Hardy, R. W., Scott, T., & Harrell, L. W. (1987) · Aquaculture · doi:10.1016/0044-8486(87)90240-7 · Cited by 182
Site and mechanism of leptin action in a rodent form of congenital lipodystrophy
Asilmaz, E., Cohen, P., Miyazaki, M., Dobrzyń, P., Ueki, K., Fayzikhodjaeva, G., Soukas, A. A., Kahn, C. R., Ntambi, J. M., Socci, N. D., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19511 · Cited by 209
The biofilm polysaccharide matrix: A buffer against changing organic substrate supply?
Freeman, C. J., & Lock, M. A. (1995) · Limnology and Oceanography · doi:10.4319/lo.1995.40.2.0273 · Cited by 182
Complement-dependent damage to liposomes prepared from pure lipids and Forssman hapten
Kinsky, S. C., Haxby, J. A., Zopf, D., et al. (1969) · Biochemistry · doi:10.1021/bi00838a036 · Cited by 182
Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin
Gerrard, J. M., & Robinson, P. (1989) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(89)90112-4 · Cited by 182
Energy-transducing H+-ATPase of Escherichia coli. Purification, reconstitution, and subunit composition.
Foster, D. L., & Fillingame, R. H. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)86880-1 · Cited by 182
The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acid on endothelial cells may be mediated via diacylglycerol kinase inhibition.
Setty, Y., Graeber, J. E., & Stuart, M. J. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45425-7 · Cited by 182
An improved high-throughput Nile red fluorescence assay for estimating intracellular lipids in a variety of yeast species
Sitepu, I. R., Ignatia, L., Franz, A. K., Wong, D. M., Faulina, S. A., Tsui, M., Kanti, A., & Boundy-Mills, K. (2012) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2012.09.001 · Cited by 180
Effect of a Sustained Reduction in Plasma Free Fatty Acid Concentration on Intramuscular Long-Chain Fatty Acyl-CoAs and Insulin Action in Type 2 Diabetic Patients
Bajaj, M., Suraamornkul, S., Romanelli, A., Cline, G. W., Mandarino, L. J., Shulman, G. I., & DeFronzo, R. A. (2005) · Diabetes · doi:10.2337/diabetes.54.11.3148 · Cited by 181
The VP1 Unique Region of Parvovirus B19 and Its Constituent Phospholipase A2-Like Activity
Dorsch, S., Liebisch, G., Kaufmann, B., von Landenberg, P., Hoffmann, J. H., Drobnik, W., & Modrow, S. (2002) · Journal of Virology · doi:10.1128/jvi.76.4.2014-2018.2002 · Cited by 180
ω-3 vs. ω-6 lipid emulsions exert differential influence on neutrophils in septic shock patients: impact on plasma fatty acids and lipid mediator generation
Mayer, K., Fegbeutel, C., Hattar, K., Sibelius, U., Krämer, H., Heuer, K.-U., Temmesfeld‐Wollbrück, B., Gokorsch, S., Grimminger, F., & Seeger, W. (2003) · Intensive Care Medicine · doi:10.1007/s00134-003-1900-2 · Cited by 182
The effects of alternative pretreatment strategies on anaerobic digestion and methane production from different algal strains
Bohutskyi, P., Betenbaugh, M. J., & Bouwer, E. J. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2013.12.095 · Cited by 187
Shotgun Lipidomics Identifies Cardiolipin Depletion in Diabetic Myocardium Linking Altered Substrate Utilization with Mitochondrial Dysfunction
Han, X., Yang, J., Cheng, H., Yang, K., Abendschein, D. R., & Gross, R. W. (2005) · Biochemistry · doi:10.1021/bi051908a · Cited by 181
Replacement of fish oil with thraustochytrid Schizochytrium sp. L oil in Atlantic salmon parr (Salmo salar L) diets
Miller, M. R., Nichols, P. D., & Carter, C. G. (2007) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2007.05.018 · Cited by 181
Seasonal Lipid Composition in Macroalgae of the Northeastern Pacific Ocean
Nelson, M. M., Phleger, C. F., & Nichols, P. D. (2002) · Botanica Marina · doi:10.1515/bot.2002.007 · Cited by 181
Comparative analysis of Klebsiella pneumoniae genomes identifies a phospholipase D family protein as a novel virulence factor
Lery, L. M., Frangeul, L., Tomas, A., Passet, V., Almeida, A. S., Bialek-Davenet, S., Barbe, V., Bengoechea, J. A., Sansonetti, P., Brisse, S., et al. (2014) · BMC Biology · doi:10.1186/1741-7007-12-41 · Cited by 181
Inhibition of gastrointestinal lipolysis by Orlistat during digestion of test meals in healthy volunteers
Carrière, F., Renou, C., Ransac, S., Lopez, V., CARO, J. D. D., Ferrato, F., Caro, A. M. D., Fleury, A., Ducray, P. S., Lengsfeld, H., et al. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.1.g16 · Cited by 180

Authors: Bligh, E. G., & Dyer, W. J.
Venue: Canadian Journal of Biochemistry and Physiology
Publisher: Canadian Science Publishing
Published: 1959-08-01
Volume: 37
Issue: 8
Pages: 911-917
ISSN: 0576-5544 (ISSN-L)
DOI: 10.1139/o59-099
OpenAlex: W2152311269
Cited by: 54,751
References: 5
Citations by year: 2026: 1149 · 2025: 1534 · 2024: 1685 · 2023: 1749 · 2022: 1802 · 2021: 2073 · 2020: 2152 · 2019: 1870 · 2018: 1737 · 2017: 1784 · 2016: 1780 · 2015: 1800 · 2014: 1786 · 2013: 1758 · 2012: 1551
FWCI: 8.73
Type: journal article
Language: en
Open access: closed
Licence: www.nrcresearchpress.com/page/about/CorporateTextAndDataMining (tdm)
Locations: Canadian Journal of Biochemistry and Physiology (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
Physical Sciences › Chemistry › Organic Chemistry › Edible Oils Quality and Analysis
Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
Keywords: lipid extraction, lipid purification, chloroform-methanol extraction, frozen fish, lipid degradation, fish muscle, tissue homogenization, rapid extraction method
MeSH terms: Fishes, Lipids

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks