Cited by 141Explainable Artificial Intelligence (XAI)Artificial Intelligence in Healthcare and EducationCOVID-19 diagnosis using AI

CheXplain: Enabling Physicians to Explore and Understand Data-Driven, AI-Enabled Medical Imaging Analysis

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Xie, Yao, Chen, Melody, Kao, David, Gao, Ge, Chen, Xiang 'Anthony'·2020·Proceedings of the 2020 CHI Conference on Human Factors in Computing Systems

Abstract

The recent development of data-driven AI promises to automate medical diagnosis; however, most AI functions as 'black boxes' to physicians with limited computational knowledge. Using medical imaging as a point of departure, we conducted three iterations of design activities to formulate CheXplain — a system that enables physicians to explore and understand AI-enabled chest X-ray analysis: (i) a paired survey between referring physicians and radiologists reveals whether, when, and what kinds of explanations are needed; (ii) a low-fidelity prototype co-designed with three physicians formulates eight key features; and (iii) a high-fidelity prototype evaluated by another six physicians provides detailed summative insights on how each feature enables the exploration and understanding of AI. We summarize by discussing recommendations for future work to design and implement explainable medical AI systems that encompass four recurring themes: motivation, constraint, explanation, and justification.

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Authors
Xie, Y., Chen, M., Kao, D., Gao, G., & Chen, X. '.
Affiliations
  • University of California, Los Angeles (US)
  • University of Maryland, College Park (US)
Venue
Proceedings of the 2020 CHI Conference on Human Factors in Computing Systems
Publisher
ACM
Published
2020-04-21
Pages
1-13
OpenAlex
W2999134777
Cited by
141
References
40
Citations by year
2026: 15 · 2025: 27 · 2024: 35 · 2023: 17 · 2022: 27 · 2021: 20
FWCI
6.10
Type
conference paper
Language
en
Open access
Locations
  • CHI Conference on Human Factors in Computing Systems (publishedVersion)
  • arXiv (Cornell University) (submittedVersion)
  • arXiv (Cornell University)
Funders
NSF (IIS-1850183)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Explainable Artificial Intelligence (XAI)
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › COVID-19 diagnosis using AI
Keywords
explainable AI, chest X-ray interpretation, diagnostic imaging, radiologists, automated medical diagnosis, prototype testing, clinical decision support

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