The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Wound Repair: Toward Understanding and Integration of Single-Cell and Multicellular Wound Responses
Open accessAbstract
The importance of wound healing to medicine and biology has long been evident, and consequently, wound healing has been the subject of intense investigation for many years. However, several relatively recent developments have added new impetus to wound repair research: the increasing application of model systems; the growing recognition that single cells have a robust, complex, and medically relevant wound healing response; and the emerging recognition that different modes of wound repair bear an uncanny resemblance to other basic biological processes such as morphogenesis and cytokinesis. In this review, each of these developments is described, and their significance for wound healing research is considered. In addition, overlapping mechanisms of single-cell and multicellular wound healing are highlighted, and it is argued that they are more similar than is often recognized. Based on this and other information, a simple model to explain the evolutionary relationships of cytokinesis, single-cell wound repair, multicellular wound repair, and developmental morphogenesis is proposed. Finally, a series of important, but as yet unanswered, questions is posed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Gurtner, G. C., Werner, S., Barrandon, Y., & Longaker, M. T. (2008) · Nature · doi:10.1038/nature07039 · Cited by 6,542
Singer, A. J., & Clark, R. A. F. (1999) · New England Journal of Medicine · doi:10.1056/nejm199909023411006 · Cited by 6,106
Mechanisms of Thrombus Formation
Furie, B., & Furie, B. C. (2008) · New England Journal of Medicine · doi:10.1056/nejmra0801082 · Cited by 1,926
Inflammatory cells during wound repair: the good, the bad and the ugly
Martin, P., & Leibovich, S. J. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.09.002 · Cited by 1,340 · cited 1×
“Furthermore, older studies provided evidence that experimental suppression of inflammation by pharmacological and other means results in impaired healing (Martin & Leibovich 2005).”
BackgroundDefective membrane repair in dysferlin-deficient muscular dystrophy
Bansal, D., Miyake, K., Vogel, S. S., Groh, S., Chen, C.-C., Williamson, R., McNeil, P. L., & Campbell, K. P. (2003) · Nature · doi:10.1038/nature01573 · Cited by 1,022
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response
Ashcroft, G. S., Yang, X., Glick, A. B., Weinstein, M., Letterio, J. J., Mizel, D. E., Anzano, M., Greenwell-Wild, T., Wahl, S. M., Deng, C., et al. (1999) · Nature Cell Biology · doi:10.1038/12971 · Cited by 911
Huh, C.-G., Factor, V. M., Sánchez, A., Uchida, K., Conner, E. A., & Thorgeirsson, S. S. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306068101 · Cited by 750
Wound healing recapitulates morphogenesis in Drosophila embryos
Wood, W., Jacinto, A., Grose, R., Woolner, S., Gale, J., Wilson, C., & Martin, P. (2002) · Nature Cell Biology · doi:10.1038/ncb875 · Cited by 435
JNK Signaling Pathway Is Required for Efficient Wound Healing in Drosophila
Rämet, M., Lanot, R., Zachary, D., & Manfruelli, P. (2002) · Developmental Biology · doi:10.1006/dbio.2001.0502 · Cited by 313
Stramer, B., Wood, W., Galko, M. J., Redd, M. J., Jacinto, A., Parkhurst, S. M., & Martin, P. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200405120 · Cited by 285
Cited by
Forcing cells into shape: the mechanics of actomyosin contractility
Murrell, M., Oakes, P. W., Lenz, M., & Gardel, M. L. (2015) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm4012 · Cited by 687
The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior
Venturini, V., Pezzano, F., Català Castro, F., Häkkinen, H.-M., Jiménez-Delgado, S., Colomer-Rosell, M., Marro, M., Tolosa-Ramon, Q., Paz-López, S., Valverde, M. A., et al. (2020) · Science · doi:10.1126/science.aba2644 · Cited by 466
Forces driving epithelial wound healing
Brugués, A., Anon, E., Conte, V., Veldhuis, J. H., Gupta, M., Colombelli, J., Muñoz, J. J., Brodland, G. W., Ladoux, B., & Trepat, X. (2014) · Nature Physics · doi:10.1038/nphys3040 · Cited by 450
Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility
Ruprecht, V., Wieser, S., Callan-Jones, A., Smutny, M., Morita, H., Sako, K., Barone, V., Ritsch-Marte, M., Sixt, M., Voituriez, R., et al. (2015) · Cell · doi:10.1016/j.cell.2015.01.008 · Cited by 437
Biomechanical regulation of contractility: spatial control and dynamics
Levayer, R., & Lecuit, T. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.10.001 · Cited by 324
Metadata
- Authors
- Sonnemann, K. J., & Bement, W. M.
- Venue
- Annual Review of Cell and Developmental Biology
- Publisher
- Annual Reviews
- Published
- 2011-11-10
- Volume
- 27
- Issue
- 1
- Pages
- 237-263
- ISSN
- 1081-0706 (ISSN-L)
- 1530-8995
- OpenAlex
- W2104463355
- Cited by
- 312
- References
- 11
- FWCI
- 3.34
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Wound Repair: Toward Understanding and Integration of Single-Cell and Multicellular Wound Responses. https://app.cochat.ai/papers/10.1146/annurev-cellbio-092910-154251
- The paper
- Sonnemann, K. J., & Bement, W. M. (2011). Wound Repair: Toward Understanding and Integration of Single-Cell and Multicellular Wound Responses. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev-cellbio-092910-154251
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
