The DOI matches its Crossref record; 302 of the 302 references it cites were found in a registry or an index.
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting
Open accessAbstract
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune responses according to peripheral cues. After four decades of research, we now know that DCs arise from a hematopoietic lineage distinct from other leukocytes, establishing the DC system as a unique hematopoietic branch. Recent work has also established that tissue DCs consist of developmentally and functionally distinct subsets that differentially regulate T lymphocyte function. This review discusses major advances in our understanding of the regulation of DC lineage commitment, differentiation, diversification, and function in situ.
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“STAT3 also plays major roles in immature DC development and function”
From Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution (2020) · cites this paper as Merad et al., 2013
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Cites
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Defining trained immunity and its role in health and disease
Netea, M. G., Domínguez-Andrés, J., Barreiro, L. B., Chavakis, T., Divangahi, M., Fuchs, E., Joosten, L. A. B., van der Meer, J. W. M., Mhlanga, M. M., Mulder, W. J. M., et al. (2020) · Nature Reviews Immunology · doi:10.1038/s41577-020-0285-6 · Cited by 2,690
Dendritic cells in cancer immunology and immunotherapy
Wculek, S. K., Cueto, F. J., Mujal, A. M., Melero, I., Krummel, M. F., & Sancho, D. (2019) · Nature reviews. Immunology · doi:10.1038/s41577-019-0210-z · Cited by 2,688
Toll-like Receptors and the Control of Immunity
Fitzgerald, K. A., & Kagan, J. C. (2020) · Cell · doi:10.1016/j.cell.2020.02.041 · Cited by 2,168
Control of adaptive immunity by the innate immune system
Iwasaki, A., & Medzhitov, R. (2015) · Nature Immunology · doi:10.1038/ni.3123 · Cited by 2,160
Böttcher, J. P., Bonavita, E., Chakravarty, P., Blees, H., Cabeza-Cabrerizo, M., Sammicheli, S., Rogers, N. C., Sahai, E., Zelenay, S., & Reis e Sousa, C. (2018) · Cell · doi:10.1016/j.cell.2018.01.004 · Cited by 1,857
Metadata
- Authors
- Merad, M., Sathe, P., Helft, J., Miller, J., & Mortha, A.
- Affiliations
- Department of Oncological Sciences,
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 2013-03-21
- Volume
- 31
- Issue
- 1
- Pages
- 563-604
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- PMC
- PMC3853342
- OpenAlex
- W2168028214
- Cited by
- 2,309
- References
- 302
- Citations by year
- 2026: 78 · 2025: 106 · 2024: 150 · 2023: 157 · 2022: 187 · 2021: 209 · 2020: 232 · 2019: 225 · 2018: 209 · 2017: 192 · 2016: 187 · 2015: 172 · 2014: 150 · 2013: 54
- FWCI
- 16.37
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Annual Review of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (R01CA173861)
- National Institute of Allergy and Infectious Diseases (U01AI095611)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Keywords
- dendritic cells, dendritic cell lineage, hematopoietic lineage, dendritic cell differentiation, dendritic cell subsets, steady-state immunity, inflammation, adaptive immune response
- MeSH terms
- Animals, Cell Differentiation, Cell Movement, Dendritic Cells, Humans, Inflammation, Lymphoid Tissue, Inflammation Mediators, Cell Lineage
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