An Integrated View of Humoral Innate Immunity: Pentraxins as a Paradigm

C-reactive protein: a critical update

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C-reactive protein: a critical update

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C1q and Mannose Binding Lectin Engagement of Cell Surface Calreticulin and Cd91 Initiates Macropinocytosis and Uptake of Apoptotic Cells

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Serum amyloid A, the major vertebrate acute‐phase reactant

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Immunoregulatory functions of surfactant proteins

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PENTRAXINS AT THE CROSSROADS BETWEEN INNATE IMMUNITY, INFLAMMATION, MATRIX DEPOSITION, AND FEMALE FERTILITY

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Genetically elevated C-reactive protein and ischemic vascular disease

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Collectins and Ficolins: Humoral Lectins of the Innate Immune Defense

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Complement evasion by human pathogens

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Evolution of the lectin–complement pathway and its role in innate immunity

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C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response

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Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

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By Binding SIRPα or Calreticulin/CD91, Lung Collectins Act as Dual Function Surveillance Molecules to Suppress or Enhance Inflammation

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The lectin‐complement pathway – its role in innate immunity and evolution

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Novel and Conventional Biomarkers for Prediction of Incident Cardiovascular Events in the Community

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The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

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Anti-Inflammatory Actions of Intravenous Immunoglobulin

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Surfactant proteins SP-A and SP-D: structure, function and receptors

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C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids

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Role of Surfactant Proteins A, D, and C1q in the Clearance of Apoptotic Cells In Vivo and In Vitro: Calreticulin and CD91 as a Common Collectin Receptor Complex

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Structure of pentameric human serum amyloid P component

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PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

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Pentraxins in Innate Immunity: From C-Reactive Protein to the Long Pentraxin PTX3

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C1q and tumor necrosis factor superfamily: modularity and versatility

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A Seven-transmembrane, G Protein–coupled Receptor, FPRL1, Mediates the Chemotactic Activity of Serum Amyloid A for Human Phagocytic Cells

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Mannose-binding lectin and its genetic variants

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Interleukin-1-inducible genes in endothelial cells. Cloning of a new gene related to C-reactive protein and serum amyloid P component.

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The Major Receptor for C-Reactive Protein on Leukocytes Is Fcγ Receptor II

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Localization of Lung Surfactant Protein D on Mucosal Surfaces in Human Tissues

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Multimer Formation and Ligand Recognition by the Long Pentraxin PTX3

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C‐reactive protein and coronary heart disease: a critical review

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Complement activation and inhibition: a delicate balance

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Three dimensional structure of human C-reactive protein

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Biochemical and functional characterization of the interaction between pentraxin 3 and C1q

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Serum amyloid A induces IL-8 secretion through a G protein–coupled receptor, FPRL1/LXA4R

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Cardioprotective Function of the Long Pentraxin PTX3 in Acute Myocardial Infarction

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Structural recognition and functional activation of FcγR by innate pentraxins

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THE OCCURRENCE DURING ACUTE INFECTIONS OF A PROTEIN NOT NORMALLY PRESENT IN THE BLOOD

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Properdin Can Initiate Complement Activation by Binding Specific Target Surfaces and Providing a Platform for De Novo Convertase Assembly

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Complexity and Complementarity of Outer Membrane Protein A Recognition by Cellular and Humoral Innate Immunity Receptors

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Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene

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Complement Receptor 1/Cd35 Is a Receptor for Mannan-Binding Lectin

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TSG-14, a tumor necrosis factor- and IL-1-inducible protein, is a novel member of the pentaxin family of acute phase proteins

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Human M-Ficolin Is a Secretory Protein That Activates the Lectin Complement Pathway

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Serum amyloid A is an innate immune opsonin for Gram-negative bacteria

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The Role of Properdin in the Assembly of the Alternative Pathway C3 Convertases of Complement

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Recognition and clearance of apoptotic cells: a role for complement and pentraxins

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Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER)—Can C-Reactive Protein Be Used to Target Statin Therapy in Primary Prevention?

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Surfactant Proteins A and D Bind CD14 by Different Mechanisms

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Surfactant Proteins A and D Suppress Alveolar Macrophage Phagocytosis via Interaction with SIRPα

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Regulation of Complement Activation by C-Reactive Protein: Targeting the Complement Inhibitory Activity of Factor H by an Interaction with Short Consensus Repeat Domains 7 and 8–11

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Structural insights into the innate immune recognition specificities of L‐ and H‐ficolins

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Antiviral Activity of the Long Chain Pentraxin PTX3 against Influenza Viruses

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The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity

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Topology and Structure of the C1q-Binding Site on C-Reactive Protein

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Purification of a Cell-surface Receptor for Surfactant Protein A

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Mannose‐Binding Lectin Regulates the Inflammatory Response of Human Professional Phagocytes toNeisseria meningitidisSerogroup B

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Binding of the Long Pentraxin PTX3 to Factor H: Interacting Domains and Function in the Regulation of Complement Activation

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DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans

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Serum Amyloid A Binding to CLA-1 (CD36 and LIMPII Analogous-1) Mediates Serum Amyloid A Protein-induced Activation of ERK1/2 and p38 Mitogen-activated Protein Kinases

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Synergy between Ficolin-2 and Pentraxin 3 Boosts Innate Immune Recognition and Complement Deposition

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Murine serum amyloid A3 is a high density apolipoprotein and is secreted by macrophages.

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TNFα-Induced Long Pentraxin PTX3 Expression in Human Lung Epithelial Cells via JNK

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Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells

Doni, A., Peri, G., Chieppa, M., Allavena, P., Pasqualini, F., Vago, L., Romani, L. R., Garlanda, C., & Mantovani, A. (2003) · European Journal of Immunology · doi:10.1002/eji.200324390 · Cited by 172

Immunodeficiency Associated with FCN3 Mutation and Ficolin-3 Deficiency

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The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens

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PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophages

Diniz, S. N., Nomizo, R., Cisalpino, P. S., Teixeira, M. M., Brown, G. D., Mantovani, A., Gordon, S., Reis, L. F. L., & Dias, A. A. M. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0803371 · Cited by 171

Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2

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Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome

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Human Mannose-binding Lectin and l-Ficolin Function as Specific Pattern Recognition Proteins in the Lectin Activation Pathway of Complement

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Maturation of dendritic cells abrogates C1q production in vivo and in vitro

Castellano, G., Woltman, A. M., Nauta, A. J., Roos, A., Trouw, L. A., Seelen, M. A., Schena, F. P., Daha, M. R., & van Kooten, C. (2004) · Blood · doi:10.1182/blood-2003-09-3046 · Cited by 165

Role of serum amyloid P component in bacterial infection: protection of the host or protection of the pathogen.

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MBL2, FCN1, FCN2 and FCN3—The genes behind the initiation of the lectin pathway of complement

Garred, P., Honoré, C., Ma, Y. J., Munthe‐Fog, L., & Hummelshøj, T. (2009) · Molecular Immunology · doi:10.1016/j.molimm.2009.05.005 · Cited by 161

M‐ficolin is expressed on monocytes and is a lectin binding to N‐acetyl‐ d ‐glucosamine and mediates monocyte adhesion and phagocytosis of Escherichia coli

Teh, C., Le, Y., Lee, S. H., & Lu, J. (2000) · Immunology · doi:10.1046/j.1365-2567.2000.00099.x · Cited by 156

Serum Amyloid A Protein Binds to Outer Membrane Protein A of Gram-negative Bacteria

Hari-Dass, R., Shah, C., Meyer, D. J., & Raynes, J. G. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500490200 · Cited by 152

PTX3 Interacts with Inter-α-trypsin Inhibitor

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Serum Amyloid P Component and C-Reactive Protein Mediate Phagocytosis Through Murine FcγRs

Mold, C., Gresham, H. D., & Clos, T. W. D. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.2.1200 · Cited by 148

Interaction of C1q with IgG1, C-reactive Protein and Pentraxin 3: Mutational Studies Using Recombinant Globular Head Modules of Human C1q A, B, and C Chains

Roumenina, L. T., Ruseva, M. M., Zlatarova, A. S., Ghai, R., Kolev, M. V., Olova, N. N., Gadjeva, M. G., Agrawal, A. C., Bottazzi, B., Mantovani, A., et al. (2006) · Biochemistry · doi:10.1021/bi052646f · Cited by 148

Human Pulmonary Surfactant Protein D Binds the Extracellular Domains of Toll-like Receptors 2 and 4 through the Carbohydrate Recognition Domain by a Mechanism Different from Its Binding to Phosphatidylinositol and Lipopolysaccharide

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Murine CD93 (C1qRp) Contributes to the Removal of Apoptotic Cells In Vivo but Is Not Required for C1q-Mediated Enhancement of Phagocytosis

Norsworthy, P. J., Fossati‐Jimack, L., Cortés-Hernández, J., Taylor, P. R., Bygrave, A. E., Thompson, R. D., Nourshargh, S., Walport, M. J., & Botto, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.6.3406 · Cited by 146

cC1q-R (calreticulin) and gC1q-R/p33: ubiquitously expressed multi-ligand binding cellular proteins involved in inflammation and infection

Ghebrehiwet, B. (2004) · Molecular Immunology · doi:10.1016/j.molimm.2004.03.014 · Cited by 145

The SARS coronavirus spike glycoprotein is selectively recognized by lung surfactant protein D and activates macrophages

Leth‐Larsen, R., Zhong, F., Chow, V. T. K., Holmskov, U., & Lu, J. (2007) · Immunobiology · doi:10.1016/j.imbio.2006.12.001 · Cited by 144

Long Pentraxin 3, a Key Component of Innate Immunity, Is Modulated by High-Density Lipoproteins in Endothelial Cells

Norata, G. D., Marchesi, P., Pirillo, A., Uboldi, P., Chiesa, G., Maina, V., Garlanda, C., Mantovani, A., & Catapano, A. L. (2008) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.160606 · Cited by 143

The Classical and Regulatory Functions of C1q in Immunity and Autoimmunity

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Specific binding of L-ficolin and H-ficolin to apoptotic cells leads to complement activation

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Pulmonary Surfactant Protein A Regulates TLR Expression and Activity in Human Macrophages

Henning, L. N., Azad, A. K., Parsa, K. V. L., Crowther, J. E., Tridandapani, S., & Schlesinger, L. S. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.12.7847 · Cited by 141

Structural Characterization of PTX3 Disulfide Bond Network and Its Multimeric Status in Cumulus Matrix Organization

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Anti- Aspergillus fumigatus Efficacy of Pentraxin 3 Alone and in Combination with Antifungals

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Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation

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Structure and Function of the Long Pentraxin PTX3 Glycosidic Moiety: Fine-Tuning of the Interaction with C1q and Complement Activation

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Pulmonary Surfactant Protein A Augments the Phagocytosis of Streptococcus pneumoniae by Alveolar Macrophages through a Casein Kinase 2-dependent Increase of Cell Surface Localization of Scavenger Receptor A

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TSG-14 transgenic mice have improved survival to endotoxemia and to CLP-induced sepsis

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C‐reactive protein collaborates with plasma lectins to boost immune response against bacteria

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The innate immune component ficolin 3 (Hakata antigen) mediates the clearance of late apoptotic cells

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Complement Factor H Binds at Two Independent Sites to C-reactive Protein in Acute Phase Concentrations*

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Human C-Reactive Protein Is Protective against FatalSalmonella entericaSerovar Typhimurium Infection in Transgenic Mice

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Collectins: sentinels of innate immunity

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Pulmonary Collectins Enhance Phagocytosis of Mycobacterium avium through Increased Activity of Mannose Receptor

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Identification of an Antiangiogenic FGF2-binding Site in the N Terminus of the Soluble Pattern Recognition Receptor PTX3

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Surfactant protein A inhibits T cell proliferation via its collagen-like tail and a 210-kDa receptor

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Serum Amyloid A Is an Endogenous Ligand That Differentially Induces IL-12 and IL-23

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Local Inflammation Induces Complement Crosstalk Which Amplifies the Antimicrobial Response

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Induction of TNF-alpha in human peripheral blood mononuclear cells by the mannoprotein of Cryptococcus neoformans involves human mannose binding protein

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Complement factor H binds to denatured rather than to native pentameric C-reactive protein

Hakobyan, S., Harris, C. L., van den Berg, C. W., Fernandez-Alonso, M. C., de Jorge, E. G., de Cordoba, S. R., Rivas, G., Mangione, P., Pepys, M. B., & Morgan, B. P. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m803648200 · Cited by 90

Dual function of the long pentraxin PTX3 in resistance against pulmonary infection with Klebsiella pneumoniae in transgenic mice

Soares, A. C., Souza, D. G., Pinho, V., Vieira, A. T., Nicoli, J. R., Cunha, F. Q., Mantovani, A., Reis, L. F. L., Dias, A. A. M., & Teixeira, M. M. (2006) · Microbes and Infection · doi:10.1016/j.micinf.2005.12.017 · Cited by 89

Cell-specific Regulation of PTX3 by Glucocorticoid Hormones in Hematopoietic and Nonhematopoietic Cells

Doni, A., Mantovani, G., Porta, C., Tuckermann, J. P., Reichardt, H. M., Kleiman, A., Sironi, M., Rubino, L., Pasqualini, F., Nebuloni, M., et al. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m805631200 · Cited by 89

Role of the Property of C-Reactive Protein to Activate the Classical Pathway of Complement in Protecting Mice from Pneumococcal Infection

Suresh, M. V., Singh, S. K., Ferguson, D. A., & Agrawal, A. C. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.7.4369 · Cited by 87

The antimicrobial activity of C-reactive protein

Szalai, A. J. (2002) · Microbes and Infection · doi:10.1016/s1286-4579(01)01528-3 · Cited by 86

Properdin Plays a Protective Role in Polymicrobial Septic Peritonitis

Stover, C. M., Luckett, J., Echtenacher, B., Dupont, A., Figgitt, S. E., Brown, J., Männel, D. N., & Schwaeble, W. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.5.3313 · Cited by 82

Human Serum Amyloid A Protein Inhibits Hepatitis C Virus Entry into Cells

Cai, Z., Cai, L., Jiang, J., Chang, K.-S., van der Westhuyzen, D. R., & Luo, G. G. (2007) · Journal of Virology · doi:10.1128/jvi.02627-06 · Cited by 81

Structure of the F‐spondin domain of mindin, an integrin ligand and pattern recognition molecule

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Surfactant protein A enhances mycobacterial killing by rat macrophages through a nitric oxide-dependent pathway

Weikert, L. F., Lopez, J. P., Abdolrasulnia, R., Chroneos, Z. C., & Shepherd, V. L. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.279.2.l216 · Cited by 78

Residue Lys57 in the Collagen-Like Region of Human L-Ficolin and Its Counterpart Lys47 in H-Ficolin Play a Key Role in the Interaction with the Mannan-Binding Lectin-Associated Serine Proteases and the Collectin Receptor Calreticulin

Lacroix, M., Dumestre‐Pérard, C., Schoehn, G., Houen, G., Cesbron, J.-Y., Arlaud, G. J., & Thielens, N. M. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.182.1.456 · Cited by 77

A Novel Mechanism of Complement Inhibition Unmasked by a Tick Salivary Protein That Binds to Properdin

Tyson, K. R., Elkins, C. A., & de Silva, A. M. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.6.3964 · Cited by 76

The α2β1 integrin: A novel collectin/C1q receptor

Zutter, M. M., & Edelson, B. T. (2007) · Immunobiology · doi:10.1016/j.imbio.2006.11.013 · Cited by 75

Autoimmunity and glomerulonephritis in mice with targeted deletion of the serum amyloid P component gene: SAP deficiency or strain combination?

Gillmore, J., Hutchinson, W., Herbert, J., Bybee, A., Mitchell, D., Hasserjian, R., Yamamura, K., Suzuki, M., Sabin, C., & Pepys, M. (2004) · Immunology · doi:10.1111/j.1365-2567.2004.01860.x · Cited by 70

Carbohydrate-binding specificities of mouse ficolin A, a splicing variant of ficolin A and ficolin B and their complex formation with MASP-2 and sMAP

Endo, Y., Nakazawa, N., Liu, Y., Iwaki, D., Takahashi, M., Fujita, T., Nakata, M., & Matsushita, M. (2005) · Immunogenetics · doi:10.1007/s00251-005-0058-1 · Cited by 65

Serum Amyloid P Component Bound to Gram-Negative Bacteria Prevents Lipopolysaccharide-Mediated Classical Pathway Complement Activation

de Haas, C. J. C., van Leeuwen, E. M. M., van Bommel, T., Verhoef, J., van Kessel, K. P. M., & van Strijp, J. A. G. (2000) · Infection and Immunity · doi:10.1128/iai.68.4.1753-1759.2000 · Cited by 65

Serum amyloid A‐induced IL‐6 production by rheumatoid synoviocytes

Koga, T., Torigoshi, T., Motokawa, S., Miyashita, T., Maeda, Y., Nakamura, M., Komori, A., Aiba, Y., Uemura, T., Yatsuhashi, H., et al. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.01.022 · Cited by 57

Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX3

Cotena, A., Maina, V., Sironi, M., Bottazzi, B., Jeannin, P., Vecchi, A., Corvaı̈a, N., Daha, M. R., Mantovani, A., & Garlanda, C. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.9.6311 · Cited by 55

Overexpression of a member of the pentraxin family (PTX3) in human soft tissue liposarcoma

Willeke, F., Assad, A., Findeisen, P., Schromm, E., Grobholz, R., von Gerstenbergk, B., Mantovani, A., Peri, S., Friess, H. H., Post, S., et al. (2006) · European Journal of Cancer · doi:10.1016/j.ejca.2006.05.035 · Cited by 55

Expression of H-ficolin/Hakata antigen, mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 by human glioma cell line T98G

Kuraya, M. (2002) · International Immunology · doi:10.1093/intimm/dxg008 · Cited by 54

Serum Amyloid P Component Binds to Influenza A Virus Haemagglutinin and Inhibits the Virus Infection In Vitro

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Human C-Reactive Protein Protects Mice from Streptococcus pneumoniae Infection without Binding to Pneumococcal C-Polysaccharide

Suresh, M. V., Singh, S. K., Ferguson, D. A., & Agrawal, A. C. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.2.1158 · Cited by 49

Serum concentration of Hakata antigen, a member of the ficolins, is linked with inhibition of Aerococcus viridans growth

Tsujimura, M., Miyazaki, T., Kojima, E., Sagara, Y., Shiraki, H., OKOCHI, K., & Maeda, Y. (2002) · Clinica Chimica Acta · doi:10.1016/s0009-8981(02)00274-7 · Cited by 48

L-Ficolin/Mannose-Binding Lectin-Associated Serine Protease Complexes Bind to Group B Streptococci Primarily through N -Acetylneuraminic Acid of Capsular Polysaccharide and Activate the Complement Pathway

Aoyagi, Y., Adderson, E. E., Rubens, C. E., Bohnsack, J. F., Min, J. G., Matsushita, M., Fujita, T., Okuwaki, Y., & Takahashi, S. (2007) · Infection and Immunity · doi:10.1128/iai.00837-07 · Cited by 46

Human C-reactive protein does not bind to fcγRIIa on phagocyti cells

Saeland, E., van Royen‐Kerkhof, A., Hendriksen, K. A. W., Vilé-Weekhout, H., Rijkers, G. T., Sanders, E. A. M., & van de Winkel, J. G. J. (2001) · Journal of Clinical Investigation · doi:10.1172/jci12418 · Cited by 45

Ficolin A and ficolin B are expressed in distinct ontogenic patterns and cell types in the mouse

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Expression of M-Ficolin in human monocytes and macrophages

Frankenberger, M., Schwaeble, W., & Ziegler‐Heitbrock, L. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2007.08.014 · Cited by 38

Genetic Variation in Pentraxin (PTX) 3 Gene Associates with PTX3 Production and Fertility in Women1

May, L., Kuningas, M., van Bodegom, D., Meij, H. J., Frölich, M., Slagboom, P. E., Mantovani, A., & Westendorp, R. G. J. (2009) · Biology of Reproduction · doi:10.1095/biolreprod.109.079111 · Cited by 38

Expression sites of the collectin SP-D suggest its importance in first line host defence: Power of combining in situ hybridisation, RT-PCR and immunohistochemistry

Herías, M. V., Hogenkamp, A., van Asten, A. J. A. M., Tersteeg‐Zijderveld, M. H. G., van Eijk, M., & Haagsman, H. P. (2007) · Molecular Immunology · doi:10.1016/j.molimm.2007.02.025 · Cited by 36

Pattern Recognition Molecule Mindin Promotes Intranasal Clearance of Influenza Viruses

Jia, W., Li, H., & He, Y.-W. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.180.9.6255 · Cited by 36

Surfactant protein‐A mRNA expression by human fetal membranes is increased in histological chorioamnionitis but not in spontaneous labour at term

Han, Y., Romero, R. J., Kim, Y., Kim, J., Richani, K., Friel, L. A., Kusanovic, J. P., Jeanty, C., Vitale, S. G., Nien, J. K., et al. (2007) · The Journal of Pathology · doi:10.1002/path.2131 · Cited by 35

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

Biswas, S. K., & Mantovani, A. (2010) · Nature Immunology · doi:10.1038/ni.1937 · Cited by 3,840

Neutrophils in the activation and regulation of innate and adaptive immunity

Mantovani, A., Cassatella, M. A., Costantini, C., & Jaillon, S. (2011) · Nature reviews. Immunology · doi:10.1038/nri3024 · Cited by 3,159

Macrophage plasticity and polarization in tissue repair and remodelling

Mantovani, A., Biswas, S. K., Galdiero, M. R., Sica, A., & Locati, M. (2013) · The Journal of Pathology · doi:10.1002/path.4133 · Cited by 2,384

Adverse childhood experiences, allostasis, allostatic load and age-related disease

Danese, A., & McEwen, B. S. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.08.019 · Cited by 2,140

Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns

Bachmann, M. F., & Jennings, G. T. (2010) · Nature reviews. Immunology · doi:10.1038/nri2868 · Cited by 2,120

Pentraxins in innate immunity: lessons from PTX3

Deban, L., Jaillon, S., Garlanda, C., Bottazzi, B., & Mantovani, A. (2010) · Cell and Tissue Research · doi:10.1007/s00441-010-1018-0 · Cited by 159

Interplay between Myeloid Cells and Humoral Innate Immunity

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Pentraxins in Humoral Innate Immunity

Inforzato, A., Bottazzi, B., Garlanda, C., Valentino, S., & Mantovani, A. (2011) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-0106-3_1 · Cited by 56

The long pentraxin PTX3 as a prototypic humoral pattern recognition receptor: interplay with cellular innate immunity

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PTX3 as a paradigm for the interaction of pentraxins with the Complement system

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