The Interaction Between Signal Regulatory Protein Alpha (SIRPα) and CD47: Structure, Function, and Therapeutic Target

Role of CD47 as a Marker of Self on Red Blood Cells

Oldenborg, P., Zheleznyak, A., Fang, Y., Lagenaur, C. F., Gresham, H. D., & Lindberg, F. P. (2000) · Science · doi:10.1126/science.288.5473.2051 · Cited by 2,018

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Majeti, R., Chao, M. P., Alizadeh, A. A., Pang, W. W., Jaiswal, S., Gibbs, K. D., van Rooijen, N., & Weissman, I. L. (2009) · Cell · doi:10.1016/j.cell.2009.05.045 · Cited by 1,752

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

Willingham, S. B., Volkmer, J.-P., Gentles, A. J., Sahoo, D., Dalerba, P. D., Mitra, S. S., Wang, J., Contreras-Trujillo, H., Martin, R. K., Cohen, J. D., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1121623109 · Cited by 1,706

CD47 Is Upregulated on Circulating Hematopoietic Stem Cells and Leukemia Cells to Avoid Phagocytosis

Jaiswal, S., Jamieson, C. H. M., Pang, W. W., Park, C. Y., Chao, M. P., Majeti, R., Traver, D. J., van Rooijen, N., & Weissman, I. L. (2009) · Cell · doi:10.1016/j.cell.2009.05.046 · Cited by 1,578

Licensing of natural killer cells by host major histocompatibility complex class I molecules

Kim, S., Poursine‐Laurent, J., Truscott, S. M., Lybarger, L. P., Song, Y.-J., Yang, L., French, A. R., Sunwoo, J. B., Lemieux, S., Hansen, T. H., et al. (2005) · Nature · doi:10.1038/nature03847 · Cited by 1,328

Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma

Chao, M. P., Alizadeh, A. A., Tang, C. Z., Myklebust, J. H., Varghese, B., Gill, S. I., Jan, M., Cha, A. C., Chan, C. K. F., Tan, B. T., et al. (2010) · Cell · doi:10.1016/j.cell.2010.07.044 · Cited by 1,124

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

Rodriguez, P. L., Harada, T., Christian, D. A., Pantano, D. A., Tsai, R. K., & Discher, D. E. (2013) · Science · doi:10.1126/science.1229568 · Cited by 1,001

Integrin-associated protein (CD47) and its ligands

Brown, E. (2001) · Trends in Cell Biology · doi:10.1016/s0962-8924(00)01906-1 · Cited by 880

Transposition mediated by RAG1 and RAG2 and its implications for the evolution of the immune system

Agrawal, A., Eastman, Q. M., & Schatz, D. G. (1998) · Nature · doi:10.1038/29457 · Cited by 811

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

Chao, M. P., Jaiswal, S., Weissman-Tsukamoto, R., Alizadeh, A. A., Gentles, A. J., Volkmer, J., Weiskopf, K., Willingham, S. B., Raveh, T., Park, C. Y., et al. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3001375 · Cited by 776

The CD47 signaling axis regulates the formation and vulnerability of atherosclerotic plaques: mechanism analysis and targeting strategies

Bai, L., Xu, B., Chen, Y., Fu, D., Wang, L., & Ma, D. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1850727 · Cited by 1

Updateon xenotransplantation for May/June 2021

Hawthorne, W. J., Fuller, E., Thomas, A., Rao, J. S., & Burlak, C. (2021) · Xenotransplantation · doi:10.1111/xen.12710 · Cited by 1

New Targets for Antiviral Therapy: Inhibitory Receptors and Immune Checkpoints on Myeloid Cells

Liu, Y., Nicklin, P. L., & He, Y. (2022) · Viruses · doi:10.3390/v14061144 · Cited by 1

A pan-allelic human SIRPα-blocking antibody, ES004-B5, promotes tumor killing by enhancing macrophage phagocytosis and subsequently inducing an effective T-cell response

Niu, X., Wang, C., Jiang, H., Gao, R. L., Lu, Y., Guo, X., Zhou, H., Cui, X., Sun, J., Qiu, Q., et al. (2024) · Antibody Therapeutics · doi:10.1093/abt/tbae022 · Cited by 1

SIRPα extracellular domain shed from neutrophils by ADAM10 aggravates sepsis via initiating nitric oxide release from erythrocyte

Liang, H., Lu, G., Bian, Z., Qu, S., Shi, L., Wang, J., Zen, K., & Liu, Y. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.08.019 · Cited by 1

Nano-decoys- future of drug delivery for the treatment of arthritis- a review

Ahmad, S., Sharma, R., Parveen, N., Basri, R., Ahmad, L., Aqil, M., Hasan, N., & Ahmad, F. J. (2025) · Biomaterials Advances · doi:10.1016/j.bioadv.2025.214598 · Cited by 1

CyTOF profiling identifies location-specific peripheral immune checkpoint and immune cell subset in mild ischemic stroke

Hang, H., Yao, Y., Wang, L., Liu, C., Zhao, J., Xu, B., Zhao, H., & Wu, G. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1739324 · Cited by 1

Theranostic of neutrophilization nanoparticles

Sun, D., Song, B., Sun, W., Li, A., Gao, Z., & Yu, D. (2026) · Progress in Materials Science · doi:10.1016/j.pmatsci.2026.101699 · Cited by 1

Myeloid cell–mediated killing of B-ALL by CD38 and CD20 IgA antibody variants is enhanced by CD47/SIRPα interference

Lustig, M., Kowol, M., Hartmann, A., van der Peet, I. C., Jansen, M., Iben, K., Winterberg, D., Krohn, S., Baumann, N., Rösner, T., et al. (2026) · Blood Neoplasia · doi:10.1016/j.bneo.2026.100242 · Cited by 1

SIRPα ablated iPSC-derived macrophages resist hypophagia and enhance mAb-dependent and CAR-mediated cytotoxicity of solid tumors

Smith, P. R., Kabir, M. E., Zhang, J., Maufort, J. P., Forsberg, M. H., Sedzro, D. M., Berres, M., Thomson, J. A., Capitini, C. M., & Slukvin, I. I. (2026) · Molecular Therapy Oncology · doi:10.1016/j.omton.2026.201240 · Cited by 1

Innate immunity in tumors: From mechanisms to therapeutics

Hu, Y., Wang, X., Ma, H., & Zheng, X. B. (2026) · Chinese Medical Journal · doi:10.1097/cm9.0000000000004116 · Cited by 1

CD90 mediates gastric cancer immune evasion though regulating IGF2BP2 to stabilize the m6A-CD47/SIRPα axis

Liu, S. M., Liang, L., Zhou, Z., Zhang, C., Liao, S., He, Q., Lei, Y., Xu, J., Luo, G., Li, Y., et al. (2026) · Cancer Cell International · doi:10.1186/s12935-026-04406-z · Cited by 1

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Nagaraj, C. K., Rima, X. Y., Nguyen, K. T., Culkins, C., Boateng, N., Doon‐Ralls, J., Bresolin, A., Huang, X., Li, H., Vahedi, A., et al. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202504351 · Cited by 1

Thrombospondin-1 and Inhibition of Tumor Growth

Jeong, G. (2015) · Korean Journal of Physical Anthropology · doi:10.11637/kjpa.2015.28.4.175 · Cited by 2

Tumor-Associated Macrophages: Therapeutic Targets of Cancer

Li, Y., Zhang, X., Zeng, X. L., Wang, S., & Wang, H. (2022) · Springer eBooks · doi:10.1007/978-3-030-84164-5_13 · Cited by 1

Role of macrophages in tumor development

Karim, M. R., Hossain, D., Uddin, A. M., & Rume, F. I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-822368-0.00007-4 · Cited by 2

Circulating Tumor Cells in Breast Cancer

Fabisiewicz, A., Szostakowska-Rodzoś, M., & Grzybowska, E. A. (2023) · Interdisciplinary cancer research · doi:10.1007/16833_2023_124 · Cited by 1

Activation of RIG‐I/MDA5 Signaling and Inhibition of CD47‐SIRPα Checkpoint with a Dual siRNA‐Assembled Nanoadjuvant for Robust Cancer Immunotherapy

Xu, X., Li, S., Yu, W., Yao, S., Fan, H., & Guo, Z. (2024) · Angewandte Chemie · doi:10.1002/ange.202318544 · Cited by 1

Erythrocyte Membrane Coating Alleviate Immune Response and Promoted Adipogenesis in Adipose Matrix

Chen, K., Guan, J., Liu, K., You, X., Xu, M., Lu, F., & He, Y. (2024) · Tissue Engineering Part A · doi:10.1089/ten.tea.2023.0354 · Cited by 1

Cancer Stem Cells: Robust Features and Therapeutic Targets

Abu-Serie, M. M., & Sarhan, E. (2024) · Interdisciplinary cancer research · doi:10.1007/16833_2024_366 · Cited by 1

Single-cell transcriptomics uncovers key immune drivers of vaccine efficacy in cattle

Wilson, A., Alexandre, P. A., Brice, A. M., Hine, B. C., Ingham, A. B., Legrand, T. P. R. A., Royle, C. M., Niemeyer, D. D. O., Reverter, A., Denman, S. E., et al. (2025) · BMC Genomics · doi:10.1186/s12864-025-11915-0 · Cited by 1

Cellular mechanisms of erythrodieresis

Korol, T. Y. (2020) · Visnyk of Lviv University Biological series · doi:10.30970/vlubs.2020.82.02 · Cited by 1

Novel Therapeutics Targeting Cancer Stem Cell Surface Markers

Gamage, S. M. K., Ranaweera, C. D., Maduwage, K. P., Cheng, T. T., Islam, F., & Gopalan, V. (2023) · Springer eBooks · doi:10.1007/978-981-99-3185-9_10 · Cited by 1

Immune checkpoint blockade: Which switches to hit and how much?

Matlung, H. L., Szilagyi, K., Kuijpers, T. W., van Lier, R. A. W., & van den Berg, T. K. (2016) · Immunology Letters · doi:10.1016/j.imlet.2016.08.014 · Cited by 1

Sirpa

Saito, Y., Murata, Y., Kotani, T., & Matozaki, T. (2017) · Springer eBooks · doi:10.1007/978-1-4614-6438-9_101830-1 · Cited by 1

NIR Light‐Activated Conversion Nanomaterials for Photothermal/Immunotherapy

Zhang, Y., & Hou, Z. (2025) · Wiley eBooks · doi:10.1002/9783527845347.ch12 · Cited by 1

When blood needs to flow: The role of the complement system in red blood cell clearance during immune responsesPreprint

Arias, C. F., Tortajada, A., Acosta, F. J., & Fernández-Arias, C. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.23.655770 · Cited by 1

Multifactorial aspects of antibody-mediated blood cell destruction

Kapur, R. (2014) · UvA-DARE (University of Amsterdam)

Defining the role of CD47 and SIRPα in murine B cell homeostasis

Kolan, S. S. (2015) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

How to avoid being eaten: a lymphoma’s defense

Heisterkamp, N. (2016) · Blood · doi:10.1182/blood-2016-03-701680

Expression and Regulation of the Cell Surface Proteins CD47 and SIRPα in Resident Periodontal Cells

Engman, S. (2016) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

Novel Role of CD47 in Obesity-Associated Metabolic Dysfunctions

Norman‐Burgdolf, H. (2016) · UKnowledge (University of Kentucky) · doi:10.13023/etd.2016.491

Macrophages: micromanagers of antagonistic signaling nanoclusters

Eggeling, C., & Davis, S. J. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201702028

[Characteristic and function of peripheral blood mononuclear cells-induced macrophages in patients with myelodysplastic syndrome].

Han, Y., Wang, H. Q., Fu, R., Qu, W., Ruan, E.-B., Wang, X. M., Wang, G. J., Wu, Y., Liu, H., Song, J., et al. (2017) · PubMed Central · doi:10.3760/cma.j.issn.0253-2727.2017.08.011

Stimulation of Glioblastoma Proliferation by Macrophages Through CD47/SIRPα

Badham, K. (2017) · uO Research (University of Ottawa) · doi:10.20381/ruor-21310

Application of Red Cell Membrane in Nanobiotechnology

Kim, I., Lee, G., & Yoon, D. S. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.84274

A single-valent long-acting human CD47 antagonist enhances antibody directed phagocytic activities

Wu, F., Qiu, Y., & Xu, Y. (2020) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-020-02640-6

Exciting progress of cancer immunotherapy focusing on immune checkpoints

Peng, Y. (2020) · E3S Web of Conferences · doi:10.1051/e3sconf/202018503007

Patent Highlights December 2020–January 2021

Mucke, H. A. (2021) · Pharmaceutical Patent Analyst · doi:10.4155/ppa-2021-0005

Application of CD47 Inhibitor in Tumor Therapy

李, 嘉. (2021) · Pharmacy Information · doi:10.12677/pi.2021.103017

Advancement of Biomimetic Nanoparticles for Targeted Drug Delivery

Sultan, A. A., Singh, A. P., Rajan, A., & Tiwary, A. (2022) · International Journal of Chemical and Environmental Sciences · doi:10.15864/ijcaes.3201

Faculty Opinions recommendation of Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells.

Kharbanda, S. M. (2021) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.739354841.793585660

Sirpa

Saito, Y., Murata, Y., Kotani, T., & Matozaki, T. (2017) · Springer eBooks · doi:10.1007/978-3-319-67199-4_101830

Faculty Opinions recommendation of Discovery of high affinity, pan-allelic, and pan-mammalian reactive antibodies against the myeloid checkpoint receptor SIRPα.

Barclay, N. (2020) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.736111376.793577593

CD47

Roberts, D. D., Isenberg, J. S., & Soto‐Pantoja, D. R. (2016) · Springer eBooks · doi:10.1007/978-1-4614-6438-9_573-1

CD47

Roberts, D. D., Isenberg, J. S., & Soto‐Pantoja, D. R. (2017) · Springer eBooks · doi:10.1007/978-3-319-67199-4_573

OX123 Recognizes Mouse SIRPβ1

(2015) · Monoclonal Antibodies in Immunodiagnosis and Immunotherapy · doi:10.1089/mab.2015.0051

[Research Progress of CD47-Related Signaling Pathway and the Role of CD47 in Pathogenic Infection].

Chen, J., Huang, Z., Zhou, X., & Cheng, L. (2022) · PubMed Central · doi:10.12182/20220560501

Data from Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity

Davra, V., Kumar, S., Geng, K., Calianese, D. C., Mehta, D., Gadiyar, V., Kasikara, C., Lahey, K. C., Chang, Y., Wichroski, M. J., et al. (2023) · doi:10.1158/0008-5472.c.6512515.v1

Understanding the Role of Microbiota in Cancer

Kaur, P., LeeNenThat, L. M., Kulshreshtha, S., & Pandohee, J. (2023) · Wiley eBooks · doi:10.1002/9781119904786.ch13

Immunotherapeutic Targeting of AML

Motabi, I., Alahmari, B., & DiPersio, J. F. (2023) · Springer eBooks · doi:10.1007/978-981-99-3810-0_15

Advanced process and methods of drug delivery process

Lu, P. (2023) · Journal of Physics Conference Series · doi:10.1088/1742-6596/2608/1/012026

CD47BPFormer: A Sequence-Based Predictor Based on Transformer to Identify CD47 Binding Peptides

Li, B., Chen, H., & He, B. (2023) · International Conference on Information Communication and Signal Processing (ICICSP) · doi:10.1109/icicsp59554.2023.10390848

HDAC Inhibition Induces CD26 Expression on Multiple Myeloma Cells via the c-Myc/Sp1-mediated Promoter Activation

Nishida, H., Suzuki, R., Nakajima, K., Hayashi, M., Morimoto, C., & Yamada, T. (2024) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0215

The Role of CD 47 in Lymphoma Biology and Strategies for Therapeutic Targeting

Krishnamoorthy, M., Uger, R. A., & Wong, M. (2024) · Wiley eBooks · doi:10.1002/9781119824572.ch14

Additional file 2 of Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours

Nabbi, A., Beck, P., Delaidelli, A., Oldridge, D. A., Sudhaman, S., Zhu, K., Yang, S. Y. C., Mulder, D. T., Bruce, J. P., Paulson, J. N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24104335

Additional file 2 of A novel multi-functionalized multicellular nanodelivery system for non-small cell lung cancer photochemotherapy

Zhang, Y., Xia, Q., Wu, T., He, Z., Li, Y., Li, Z., Hou, X., He, Y., Ruan, S., Wang, Z., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15178967

Signal Regulatory Protein α Expression in Systemic Vasculitis

Banerjee, S., Rose, E. L., Panicker, S., Dugan, J., KHALIDI, N. A., Koening, C. L., Langford, C. A., Monach, P. A., Pagnoux, C., McAlear, C. A., et al. (2024) · ACR Open Rheumatology · doi:10.1002/acr2.11716

The expression of signal regulatory protein alpha (SIRPα) in periodontal cells and tissue

Holm, C. K., Rosendahl, S., Oldenborg, P., & Lundberg, P. (2024) · Acta Odontologica Scandinavica · doi:10.2340/aos.v83.41391

Encrypting Cancer’s Morse Code: The Synergistic Power of CD47-SIRPα Blockade and Tyrosine Kinase Inhibition

Hirsi, M., Lahrach, Y., Abdirahman, A. M., Nazir, A., Barre, M. E., Dinle, Y. Y. H., Alkhatib, A. W., & Nagendrappa, B. R. (2025) · International Journal of Clinical Medicine · doi:10.4236/ijcm.2025.162009

Cell Death in Atherosclerosis: Apoptosis? Or Necrosis? Or More?

Watanabe, T., & Fan, J. (2025) · Springer eBooks · doi:10.1007/978-981-96-3675-4_8

A Quantitative Assessment of the Phagocytosis of Allogeneic and Xenogeneic Erythrocytes by Rat Macrophages In Vitro

Lu, Y., Ding, M., Huang, X.-L., Xiong, Y., Wu, T.-X., Zhang, L., Gao, F., Ge, J., Li, Y., Hui, L., et al. (2025) · Journal of Visualized Experiments · doi:10.3791/68904

Iron Oxide Nanoparticle Uptake, Toxicity, and Steroidogenesis in Adrenocortical Carcinoma Cells Using a Multicellular in vitro Model

Challapalli, R. S., Hong, C., Sorushanova, A., Covarrubias‐Zambrano, O., Mullen, N., Feely, S., Covarrubias, J., Varghese, S. N., Hantel, C., Owens, P., et al. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s519937

Network Activity Shapes Inhibitory Synaptic Development in the Mouse Hippocampus

Johnson‐Venkatesh, E., & Umemori, H. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1182-24.2025

Innate Immune Defence

Lepage, M., & Dubois, V. (2025) · Wiley eBooks · doi:10.1002/9783527847617.ch1

Research Highlights

Mohammadi, F., & Luo, X. (2025) · Transplantation · doi:10.1097/tp.0000000000005523

The impact of repetitive neonatal procedural pain on cognitive behavioral development in male Mice: A microglial Perspective

Wang, Y., Ling, R., Zheng, W., Xia, D., Min, C., Chen, M., Zhou, W., & Li, X. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.106182

CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice

Gwag, T., Newcomb, A., Otuagomah, J., Murray, S., Guo, S., Tong, S., Kern, P. A., & Wang, S. (2025) · Aging · doi:10.18632/aging.206343

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Cao, Y., Chai, S., Li, M., Chen, X., Hu, J., Lin, B., Wu, L., Yi, W., & Zhu, Q. (2025) · Advanced Science · doi:10.1002/advs.202516863

Additional file 1 of Exploration of the combined role of immune checkpoints and immune cells in the diagnosis and treatment of ankylosing spondylitis: a preliminary study immune checkpoints in ankylosing spondylitis

Huang, F., Su, Z., Huang, Y., Huang, Y., Zhou, C., Feng, S., Qin, X., Xie, X., Liu, C., & Yu, C. (2024) · Figshare · doi:10.6084/m9.figshare.26729500

Additional file 1 of A pH-dependent anti-CD47 antibody that selectively targets solid tumors and improves therapeutic efficacy and safety

Li, Y., Liu, J., Chen, W., Wang, W., Yang, F., Liu, X., Sheng, Y., Du, K., He, M., Lyu, X., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22612043

Additional file 3 of Exploration of the combined role of immune checkpoints and immune cells in the diagnosis and treatment of ankylosing spondylitis: a preliminary study immune checkpoints in ankylosing spondylitis

Huang, F., Su, Z., Huang, Y., Huang, Y., Zhou, C., Feng, S., Qin, X., Xie, X., Liu, C., & Yu, C. (2024) · Figshare · doi:10.6084/m9.figshare.26729506

Additional file 6 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26663005

Additional file 8 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26663011

Additional file 1 of Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours

Nabbi, A., Beck, P., Delaidelli, A., Oldridge, D. A., Sudhaman, S., Zhu, K., Yang, S. Y. C., Mulder, D. T., Bruce, J. P., Paulson, J. N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.24104332

Additional file 3 of The intratumoral microbiota biomarkers for predicting survival and efficacy of immunotherapy in patients with ovarian serous cystadenocarcinoma

Qin, H., Liu, J., Qu, Y., Li, Y.-Y., Xu, Y.-L., & Yan, Y.-F. (2024) · Figshare · doi:10.6084/m9.figshare.26744327

Additional file 4 of Exploration of the combined role of immune checkpoints and immune cells in the diagnosis and treatment of ankylosing spondylitis: a preliminary study immune checkpoints in ankylosing spondylitis

Huang, F., Su, Z., Huang, Y., Huang, Y., Zhou, C., Feng, S., Qin, X., Xie, X., Liu, C., & Yu, C. (2024) · Figshare · doi:10.6084/m9.figshare.26729509

Additional file 3 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26662996

Additional file 5 of Exploration of the combined role of immune checkpoints and immune cells in the diagnosis and treatment of ankylosing spondylitis: a preliminary study immune checkpoints in ankylosing spondylitis

Huang, F., Su, Z., Huang, Y., Huang, Y., Zhou, C., Feng, S., Qin, X., Xie, X., Liu, C., & Yu, C. (2024) · Figshare · doi:10.6084/m9.figshare.26729512

Additional file 6 of BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma

Lu, Q., Li, H., Wu, Z., Zhu, Z., Zhang, Z., Yang, D., & Tong, A. (2024) · Figshare · doi:10.6084/m9.figshare.26724467

Additional file 6 of Exploration of the combined role of immune checkpoints and immune cells in the diagnosis and treatment of ankylosing spondylitis: a preliminary study immune checkpoints in ankylosing spondylitis

Huang, F., Su, Z., Huang, Y., Huang, Y., Zhou, C., Feng, S., Qin, X., Xie, X., Liu, C., & Yu, C. (2024) · Figshare · doi:10.6084/m9.figshare.26729515

Additional file 9 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26663014

Additional file 2 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26662993

Additional file 3 of BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma

Lu, Q., Li, H., Wu, Z., Zhu, Z., Zhang, Z., Yang, D., & Tong, A. (2024) · Figshare · doi:10.6084/m9.figshare.26724449

Additional file 10 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26663017

Additional file 1 of Multifunctional exosome-mimetics for targeted anti-glioblastoma therapy by manipulating protein corona

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Additional file 4 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

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Additional file 5 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

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Additional file 2 of The intratumoral microbiota biomarkers for predicting survival and efficacy of immunotherapy in patients with ovarian serous cystadenocarcinoma

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Additional file 2 of BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma

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Additional file 5 of BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma

Lu, Q., Li, H., Wu, Z., Zhu, Z., Zhang, Z., Yang, D., & Tong, A. (2024) · Figshare · doi:10.6084/m9.figshare.26724461

Additional file 1 of The intratumoral microbiota biomarkers for predicting survival and efficacy of immunotherapy in patients with ovarian serous cystadenocarcinoma

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Additional file 1 of BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma

Lu, Q., Li, H., Wu, Z., Zhu, Z., Zhang, Z., Yang, D., & Tong, A. (2024) · Figshare · doi:10.6084/m9.figshare.25893743

Additional file 7 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26663008

Additional file 4 of BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma

Lu, Q., Li, H., Wu, Z., Zhu, Z., Zhang, Z., Yang, D., & Tong, A. (2024) · Figshare · doi:10.6084/m9.figshare.26724455

Additional file 1 of Hypoxia-induced ZEB1 promotes cervical cancer immune evasion by strengthening the CD47-SIRPα axis

Chen, X.-J., Guo, C.-H., Wang, Z.-C., Yang, Y., Pan, Y., Liang, J.-Y., Sun, M., Fan, L.-S., Liang, L., & Wang, W. (2024) · Figshare · doi:10.6084/m9.figshare.26662990

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