The DOI matches its Crossref record; 102 of the 102 references it cites were found in a registry or an index.
Assembly of Bacterial Capsular Polysaccharides and Exopolysaccharides
Abstract
Polysaccharides are dominant features of most bacterial surfaces and are displayed in different formats. Many bacteria produce abundant long-chain capsular polysaccharides, which can maintain a strong association and form a capsule structure enveloping the cell and/or take the form of exopolysaccharides that are mostly secreted into the immediate environment. These polymers afford the producing bacteria protection from a wide range of physical, chemical, and biological stresses, support biofilms, and play critical roles in interactions between bacteria and their immediate environments. Their biological and physical properties also drive a variety of industrial and biomedical applications. Despite the immense variation in capsular polysaccharide and exopolysaccharide structures, patterns are evident in strategies used for their assembly and export. This review describes recent advances in understanding those strategies, based on a wealth of biochemical investigations of select prototypes, supported by complementary insight from expanding structural biology initiatives. This provides a framework to identify and distinguish new systems emanating from genomic studies.
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Cites
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Self-citationBacterial Extracellular Polysaccharides in Biofilm Formation and Function
Limoli, D. H., Jones, C. J., & Wozniak, D. J. (2015) · Microbiology Spectrum · doi:10.1128/microbiolspec.mb-0011-2014 · Cited by 924
Novel and established applications of microbial polysaccharides
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Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies
Schmid, J., Sieber, V., & Rehm, B. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00496 · Cited by 611
Crystallographic snapshot of cellulose synthesis and membrane translocation
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Flemming, H.-C., van Hullebusch, E. D., Neu, T. R., Nielsen, P. H., Seviour, T., Stoodley, P., Wingender, J., & Wuertz, S. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-022-00791-0 · Cited by 983
Karampatakis, T., Tsergouli, K., & Behzadi, P. (2023) · Antibiotics · doi:10.3390/antibiotics12020234 · Cited by 339
Capsules and their traits shape phage susceptibility and plasmid conjugation efficiency
Haudiquet, M., Le Bris, J., Nucci, A., Bonnin, R. A., Domingo-Calap, P., Rocha, E. P. C., & Rendueles, O. (2024) · Nature Communications · doi:10.1038/s41467-024-46147-5 · Cited by 72
Host and microbiota metabolic signals in aging and longevity
Zhou, Y., Hu, G., & Wang, M. C. (2021) · Nature Chemical Biology · doi:10.1038/s41589-021-00837-z · Cited by 70
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Metadata
- Authors
- Whitfield, C., Wear, S. S., & Sande, C.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2020-09-08
- Volume
- 74
- Issue
- 1
- Pages
- 521-543
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W3043527632
- Cited by
- 308
- References
- 102
- FWCI
- 4.59
- Type
- journal article
- Language
- en
- Open access
- closed
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