The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Neutrophils Versus Staphylococcus aureus: A Biological Tug of War
Open accessAbstract
The pathogen Staphylococcus aureus is well adapted to its human host. Neutrophil-mediated killing is a crucial defense system against S. aureus; however, the pathogen has evolved many strategies to resist killing. We first describe the discrete steps of neutrophil activation and migration to the site of infection and the killing of microbes by neutrophils in general. We then highlight the different approaches utilized by S. aureus to resist the different steps of neutrophil attack. Various molecules are discussed in their evolutionary context. Most of the molecules secreted by S. aureus to combat neutrophil attacks at the site of infection show clear human specificity. Many elements of human neutrophil defenses appear redundant, and so the evasion strategies of staphylococci display redundant functions as well. All efforts by S. aureus to resist neutrophil-mediated killing stress the importance of these mechanisms in the pathophysiology of staphylococcal diseases. However, the highly human-specific nature of most host-pathogen interactions hinders the in vivo establishment of their contribution to staphylococcal pathophysiology.
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Cites
Neutrophil Extracellular Traps Kill Bacteria
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Getting to the site of inflammation: the leukocyte adhesion cascade updated
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Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo
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Cited by
Neutrophil extracellular traps in immunity and disease
Papayannopoulos, V. (2018) · Nature Reviews Immunology · doi:10.1038/nri.2017.105 · Cited by 3,397
Staphylococcus aureus host interactions and adaptation
Howden, B. P., Giulieri, S. G., Wong Fok Lung, T., Baines, S. L., Sharkey, L. K., Lee, J. Y. H., Hachani, A., Monk, I. R., & Stinear, T. P. (2023) · Nature Reviews Microbiology · doi:10.1038/s41579-023-00852-y · Cited by 689
Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
Neupane, A. S., Willson, M., Chojnacki, A. K., Vargas E Silva Castanheira, F., Morehouse, C., Carestia, A., Keller, A. E., Peiseler, M., DiGiandomenico, A., Kelly, M. M., et al. (2020) · Cell · doi:10.1016/j.cell.2020.08.020 · Cited by 348
Basis of Virulence in Enterotoxin-Mediated Staphylococcal Food Poisoning
Fisher, E. L., Otto, M., & Cheung, G. Y. C. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00436 · Cited by 285
The Bicomponent Pore-Forming Leucocidins of Staphylococcus aureus
Alonzo, F., & Torres, V. J. (2014) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00055-13 · Cited by 276
Metadata
- Authors
- Spaan, A. N., Surewaard, B. G. J., Nijland, R., & van Strijp, J. A. G.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2013-09-08
- Volume
- 67
- Issue
- 1
- Pages
- 629-650
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2166227322
- Cited by
- 307
- References
- 14
- FWCI
- 3.99
- Type
- journal article
- Language
- en
- Open access
- green
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- Spaan, A. N., Surewaard, B. G. J., Nijland, R., & van Strijp, J. A. G. (2013). Neutrophils Versus Staphylococcus aureus: A Biological Tug of War. Annual Review of Microbiology. https://doi.org/10.1146/annurev-micro-092412-155746
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