A CONSERVED SIGNALING PATHWAY: The Drosophila Toll-Dorsal Pathway

Belvin, Marcia P., Anderson, Kathryn V.·1996·Annual Review of Cell and Developmental Biology

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Items 101–200 of 750

  1. Involvement of CD14 and Toll-Like Receptors in Activation of Human Monocytes by Aspergillus fumigatus Hyphae
    Jacob E. Wang, A. Warris, E. A. Ellingsen, P. Jørgensen, T. Flo, T. Espevik, R. Solberg, P. Verweij, A. Aasen · 2001 · Infection and Immunity
  2. Molecular basis of endothelial dysfunction in sepsis.
    K. Peters, R. Unger, J. Brunner, C. Kirkpatrick · 2003 · Cardiovascular Research
  3. Gene Expression of Osteoclast Differentiation Factor Is Induced by Lipopolysaccharide in Mouse Osteoblasts Via Toll-Like Receptors
    Takeshi Kikuchi, Tetsuya Matsuguchi, Naotake Tsuboi, Akio Mitani, Shigehisa Tanaka, Masanori Matsuoka, Genta Yamamoto, Toshimitsu Hishikawa, Toshihide Noguchi, Yasunobu Yoshikai · 2001 · The Journal of Immunology
  4. Insect immunity: evolutionary roots of the mammalian innate immune system
    Péter Vilmos · 1998 · Immunology Letters
  5. Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.
    P. Chaudhary, C. Ferguson, Vilaska Nguyen, Oanh Nguyen, H. Massa, M. Eby, A. Jasmin, B. Trask, Leroy Hood, P. S. Nelson · 1998 · Blood
  6. Mode of action of linear amphipathic α-helical antimicrobial peptides
    Oren Ziv, Yechiel Shai · 1998 · Biopolymers
  7. Involvement of ERK, p38 and NF‐κB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells
    Hua-Zhang An, Yi-Zhi Yu, Ming-Hui Zhang, Hong-Mei Xu, Run-Zi Qi, Xiaoyi Yan, Shu-Xun Liu, Wen-Ya Wang, Zhenghong Guo, Jun Guo et al. · 2002 · Immunology
  8. Toll Receptors: a Central Element in Innate Immune Responses
    Thierry Vasselon, Patricia A. Detmers · 2002 · Infection and Immunity
  9. Expression and regulation of the pattern recognition receptors Toll‐like receptor‐2 and Toll‐like receptor‐4 in the human placenta
    Ulrika Holmlund, Gvido Cebers, Agneta Richter‐Dahlfors, Bengt Sandstedt, Katarina Bremme, Eva Sverremark‐Ekström, Annika Scheynius · 2002 · Immunology
  10. Evolutionary History and Stress Regulation of Plant Receptor-Like Kinase/Pelle Genes1[W][OA]
    M. Lehti-Shiu, C. Zou, Kousuke Hanada, S. Shiu · 2009 · Plant Physiology
  11. The immune response of Drosophila melanogaster
    V. Leclerc, J. Reichhart · 2004 · Immunological Reviews
  12. No increased risk of malignancies and mortality in cyclosporin A-treated patients with rheumatoid arthritis
    B. E. E. M. van den Borne, R. B. M. Landew�, I. Houkes, F. Schild, P. C. W. van der Heyden, J. M. W. Hazes, Jan Paul Vandenbroucke, Aeilko H. Zwinderman, H. S. Goei Thè, Ferdinand C. Breedveld et al. · 1998 · Arthritis & Rheumatism
  13. Important aspects of Toll-like receptors, ligands and their signaling pathways
    Z L Chang · 2010 · Inflammation Research
  14. Cutting Edge: The Toll Pathway Is Required for Resistance to Gram-Positive Bacterial Infections in Drosophila1
    S. Rutschmann, A. Kilinç, D. Ferrandon · 2002 · Journal of Immunology
  15. NF‐κB: where did it come from and why?
    Thomas D. Gilmore, Francis S. Wolenski · 2012 · Immunological Reviews
  16. Structural Complementarity of Toll/Interleukin-1 Receptor Domains in Toll-like Receptors and the Adaptors Mal and MyD88
    Aisling Dunne, Mikael Ejdebäck, Phumzile L. Ludidi, Luke A.J. O'Neill, Nicholas J. Gay · 2003 · Journal of Biological Chemistry
  17. TLR2: cellular sensor for microbial and endogenous molecular patterns.
    C. Kirschning, R. Schumann · 2002 · Current Topics in Microbiology and Immunology
  18. Caspar Controls Resistance to Plasmodium falciparum in Diverse Anopheline Species
    Lindsey S. Garver, Yue-Mei Dong, G. Dimopoulos · 2009 · PLoS Pathogens
  19. Peptidoglycan recognition proteins: on and off switches for innate immunity
    H. Steiner · 2004 · Immunological Reviews
  20. IRAK-4 as the central TIR signaling mediator in innate immunity
    Nobutaka Suzuki, Shinobu Suzuki, Wen‐Chen Yeh · 2002 · Trends in Immunology
  21. The Role of Toll-like Receptors (TLRs) in Bacteria-induced Maturation of Murine Dendritic Cells (DCs)
    K. Michelsen, A. Aicher, Mariette Mohaupt, T. Hartung, S. Dimmeler, C. Kirschning, R. Schumann · 2001 · Journal of Biological Chemistry
  22. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF
    P. Manfruelli, J. Reichhart, R. Steward, Jules A. Hoffmann, B. Lemaître · 1999 · EMBO Journal
  23. Positive and negative regulation of EAAT2 by NF‐κB: a role for N‐myc in TNFα‐controlled repression
    R. Sitcheran, P. Gupta, P. Fisher, A. Baldwin · 2005 · The EMBO Journal
  24. The mosquito microbiota influences vector competence for human pathogens
    Nathan J. Dennison, Natapong Jupatanakul, G. Dimopoulos · 2014 · Current Opinion in Insect Science
  25. The road to Toll
    B. Lemaître · 2004 · Nature reviews. Immunology
  26. Signaling mechanisms in the antimicrobial host defense of Drosophila.
    J. Imler, J. Hoffmann · 2000 · Current Opinion in Microbiology
  27. Interleukin (IL)-1 Receptor–associated Kinase (IRAK) Requirement for Optimal Induction of Multiple IL-1 Signaling Pathways and IL-6 Production
    Palanisamy Kanakaraj, P. Schafer, D. Cavender, Ying Wu, K. Ngo, P. Grealish, S. Wadsworth, P. A. Peterson, J. Siekierka, Crafford A. Harris et al. · 1998 · Journal of Experimental Medicine
  28. Interleukin-1 and cutaneous inflammation: a crucial link between innate and acquired immunity.
    J. Murphy, Caroline Robert, T. Kupper · 2000 · Journal of Investigative Dermatology
  29. Fungi as elicitors of insect immune responses.
    J. P. Gillespie, A. Bailey, B. Cobb, A. Vilcinskas · 2000 · Archives of Insect Biochemistry and Physiology
  30. A Conserved p38 Mitogen-Activated Protein Kinase Pathway Regulates Drosophila Immunity Gene Expression
    Zhiqiang Han, H. Enslen, Xiaodi Hu, Xiang-Jun Meng, I-Huan Wu, T. Barrett, R. Davis, Y. Ip · 1998 · Molecular and Cellular Biology
  31. The role of interleukin-13 in infectious diseases and allergy
    Frank Brombacher · 2000 · BioEssays
  32. The role of Toll-like receptors in renal diseases
    Anna Gluba-Brzózka, Maciej Banach, Simon Hannam, Dimitri P. Mikhailidis, Agata Sakowicz, Jacek Rysz · 2010 · Nature Reviews Nephrology
  33. Neutrophil-Kupffer cell interaction: a critical component of host defenses to systemic bacterial infections
    Stephen H. Gregory, Edward J. Wing · 2002 · Journal of Leukocyte Biology
  34. Clinical implications of antibiotic-induced endotoxin release in septic shock
    Philipp M. Lepper, T. Held, E. Marion Schneider, Edwin Bölke, Herwig Gerlach, Matthias Trautmann · 2002 · Intensive Care Medicine
  35. Toll-like receptors as molecular switches
    N. Gay, M. Gangloff, A. Weber · 2006 · Nature reviews. Immunology
  36. Caenorhabditis elegans: an emerging genetic model for the study of innate immunity
    C. Léopold Kurz, Jonathan J. Ewbank · 2003 · Nature Reviews Genetics
  37. Dorsal gradient networks in the Drosophila embryo.
    A. Stathopoulos, M. Levine · 2002 · Developmental Biology
  38. Defective Interleukin (IL)-18–mediated Natural Killer and T Helper Cell Type 1 Responses in IL-1 Receptor–associated Kinase (IRAK)-deficient Mice
    Palanisamy Kanakaraj, Karen Ngo, Ying Wu, Ana Angulo, Peter Ghazal, Crafford A. Harris, John J. Siekierka, Per A. Peterson, Wai‐Ping Fung‐Leung · 1999 · The Journal of Experimental Medicine
  39. Listeria monocytogenes: clinical and experimental update.
    E. Wing, S. Gregory · 2002 · Journal of Infectious Diseases
  40. Antimicrobial peptide defense in Drosophila
    M. Meister, B. Lemaître, Jules A. Hoffmann · 1997 · Bioessays
  41. Systemic Inflammatory Response Syndrome (SIRS): Molecular Pathophysiology and Gene Therapy
    Naoyuki Matsuda, Yuichi Hattori · 2006 · Journal of Pharmacological Sciences
  42. Comparative analysis of serine protease-related genes in the honey bee genome: possible involvement in embryonic development and innate immunity
    Z. Zou, Dawn L. Lopez, M. Kanost, J. Evans, Hao-Bo Jiang · 2006 · Insect molecular biology (Print)
  43. Evolutionary Origins of Toll-like Receptor Signaling
    Joseph J. Brennan, Thomas D. Gilmore · 2018 · Molecular Biology and Evolution
  44. A Toll receptor from Chinese shrimp Fenneropenaeus chinensis is responsive to Vibrio anguillarum infection
    C YANG, Jiquan Zhang, Fei Li, Hongming Ma, Q ZHANG, T.A. Jose Priya, X ZHANG, Jianhai Xiang · 2008 · Fish & Shellfish Immunology
  45. The T cell as a bridge between innate and adaptive immune systems: Implications for the kidney
    Hamid Rabb · 2002 · Kidney International
  46. Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages
    D. O'Mahony, Uyenvy Pham, R. Iyer, T. Hawn, W. Liles · 2008 · International Journal of Medical Sciences
  47. Biology of Toll receptors: lessons from insects and mammals
    Jean‐Luc Imler, Liangbiao Zheng · 2003 · Journal of Leukocyte Biology
  48. Gene expressions of lipopolysaccharide receptors, toll-like receptors 2 and 4, are differently regulated in mouse T lymphocytes
    Tetsuya Matsuguchi, Kensuke Takagi, Tipayaratn Musikacharoen, Yasunobu Yoshikai · 2000 · Blood
  49. Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling
    Salminen, Antero, Kaarniranta, Kai · 2010 · Cellular Signalling
  50. Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines, chemokines, and intercellular adhesion molecule-1.
    H. Takano, R. Yanagisawa, T. Ichinose, K. Sadakane, S. Yoshino, T. Yoshikawa, M. Morita · 2002 · American Journal of Respiratory and Critical Care Medicine
  51. Degranulation of paneth cells via toll-like receptor 9.
    C. Rumio, D. Besusso, M. Palazzo, S. Selleri, L. Sfondrini, F. Dubini, S. Ménard, A. Balsari · 2004 · American Journal of Pathology
  52. Toll-Like Receptors and Their Function in Innate and Adaptive Immunity
    Holger Heine, Egil Lien · 2003 · International Archives of Allergy and Immunology
  53. Absence of Toll-Like Receptor 4 Explains Endotoxin Hyporesponsiveness in Human Intestinal Epithelium
    S. Naik, Eric J. Kelly, L. Meijer, S. Pettersson, I. Sanderson · 2001 · Journal of Pediatric Gastroenterology and Nutrition - JPGN
  54. High frequency of T9 and CFTR mutations in children with idiopathic bronchiectasis
    Vasiliki Ninidu Ninis · 2003 · Journal of Medical Genetics · Retracted
  55. Natural endogenous adjuvants
    Kenneth L. Rock, Arron R. Hearn, Chun‐Jen Chen, Yan Shi · 2004 · Springer Seminars in Immunopathology
  56. A Toll receptor in shrimp
    Lishi Yang, Zhi-Xin Yin, Ji-Xiang Liao, Xiande Huang, Chang-Jun Guo, Shaoping Weng, Siu-Ming Chan, Xiao‐Qiang Yu, Jianguo He · 2006 · Molecular Immunology
  57. RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides
    Haoyang Li, Bin Yin, Sheng Wang, Qihui Fu, Bang Xiao, Kai Lǚ, Jianguo He, Chaozheng Li · 2018 · PLoS Pathogens
  58. Role of Leucine-Rich Repeat Proteins in the Development and Function of Neural Circuits
    Joris de Wit, Weizhe Hong, Liqun Luo, Anirvan Ghosh · 2011 · Annual Review of Cell and Developmental Biology
  59. Current concepts of active defense in plants.
    S. Hutcheson · 1998 · Annual Review of Phytopathology
  60. Genes that fight infection:what the Drosophila genome says about animal immunity
    Ranjiv S Khush, Bruno Lemaître · 2000 · Trends in Genetics
  61. Toll‐like receptors: molecular mechanisms of the mammalian immune response
    Hans D. Brightbill, Robert L. Modlin · 2000 · Immunology
  62. A heterotrimeric death domain complex in Toll signaling
    Huaiyu Sun, Benjamin N. Bristow, Guowei Qu, Steven A. Wasserman · 2002 · Proceedings of the National Academy of Sciences
  63. Drosophila immunity: two paths to NF-κB
    R. Khush, F. Leulier, B. Lemaître · 2001 · Trends in Immunology
  64. The Insect Microbiome Modulates Vector Competence for Arboviruses
    Natapong Jupatanakul, Shuzhen Sim, G. Dimopoulos · 2014 · Viruses
  65. DELLA Proteins and Their Interacting RING Finger Proteins Repress Gibberellin Responses by Binding to the Promoters of a Subset of Gibberellin-Responsive Genes in Arabidopsis[C][W]
    Jeongmoo Park, Khoa Thi Nguyen, Eunae Park, J. Jeon, G. Choi · 2013 · The Plant Cell
  66. A primitive Toll-like receptor signaling pathway in mollusk Zhikong scallop Chlamys farreri
    Mengqiang Wang, Jialong Yang, Zhi Zhou, Limei Qiu, Lingling Wang, Huan Zhang, Yang Gao, Xingqiang Wang, Li Zhang, Jianmin Zhao et al. · 2010 · Developmental & Comparative Immunology
  67. Functions of Manduca sexta Hemolymph Proteinases HP6 and HP8 in Two Innate Immune Pathways*
    C. An, J. Ishibashi, Emily J. Ragan, Hao-Bo Jiang, M. Kanost · 2009 · Journal of Biological Chemistry
  68. Toll‐Like Receptors
    Kiyoshi Takeda, Shizuo Akira · 2007 · Current Protocols in Immunology
  69. Innate immune induction of the adaptive immune response.
    R. Medzhitov, C. Janeway · 1999 · Cold Spring Harbor Symposia on Quantitative Biology
  70. Peptidoglycan and Lipoteichoic Acid in Gram-Positive Bacterial Sepsis: Receptors, Signal Transduction, Biological Effects, and Synergism
    Jacob E. Wang, Maria K. Dahle, Michelle C. McDonald, Simon J. Foster, Ansgar Oddne Aasen, Christoph Thiemermann · 2003 · Shock
  71. Toll-like receptors and their role in experimental models of microbial infection
    S. Qureshi, R. Medzhitov · 2003 · Genes and Immunity
  72. From periphery to center stage: 50 years of advancements in innate immunity
    Susan Carpenter, Luke A. J. O'Neill · 2024 · Cell
  73. TLR4 and TNF-α polymorphisms are associated with an increased risk for severe sepsis following burn injury
    Robert C. Barber, Corinne Aragaki, Fernando A. Rivera-Chávez, Gary F. Purdue, John L. Hunt, Jureta W. Horton · 2004 · Journal of Medical Genetics
  74. Role of Toll‐like receptor 4 in the initiation and progression of atherosclerotic disease
    Gerard Pasterkamp, J. Karlijn van Keulen, Dominique P.V. de Kleijn · 2004 · European Journal of Clinical Investigation
  75. A Link between Blood Coagulation and Prophenol Oxidase Activation in Arthropod Host Defense*
    Takushi Nagai, S. Kawabata · 2000 · Journal of Biological Chemistry
  76. Immunohistochemical distribution of Toll-like receptor 4 in term and preterm human placentas from normal and complicated pregnancy including chorioamnionitis
    Kaori Kumazaki, Masahiro Nakayama, Itaru Yanagihara, Noriyuki Suehara, Yoshinao Wada · 2004 · Human Pathology
  77. Interaction of entomopathogenic fungi with the host immune system.
    S. Qu, Si-Bao Wang · 2018 · Developmental and Comparative Immunology
  78. The scope of the crustacean immune system for disease control.
    C. Hauton · 2012 · Journal of Invertebrate Pathology
  79. Induction and regulation of antimicrobial peptides in Drosophila.
    Y. Engström · 1999 · Developmental and Comparative Immunology
  80. The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species
    Alexie Papanicolaou, Marc F. Schetelig, Peter Arensburger, Peter W. Atkinson, Joshua B. Benoit, Kostas Bourtzis, Pedro Castañera, John P. Cavanaugh, Hsu Chao, Christopher P. Childers et al. · 2016 · Genome biology
  81. Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease
    Jane A. Mitchell, Mark J. Paul‐Clark, Graham W. Clarke, Shaun K. McMaster, Neil Cartwright · 2007 · Journal of Endocrinology
  82. Toll-like receptors: how they work and what they do
    B. Beutler · 2002 · Current opinion in hematology
  83. The modular nature of apoptotic signaling proteins
    Kay Hofmann · 1999 · Cellular and Molecular Life Sciences (CMLS)
  84. Modulation of pattern recognition receptor-mediated inflammation and risk of chronic diseases by dietary fatty acids
    Joo Young Lee, Ling Zhao, Daniel H. Hwang · 2009 · Nutrition Reviews
  85. Conventional and non-conventional Drosophila Toll signaling
    Scott A. Lindsay, Steven A. Wasserman · 2013 · Developmental & Comparative Immunology
  86. Characterization of gene structure and expression of two toll-like receptors from Japanese flounder, Paralichthys olivaceus
    I. Hirono, Mariko Takami, M. Miyata, T. Miyazaki, Hyun-Ja Han, Tomokazu Takano, M. Endo, T. Aoki · 2004 · Immunogenetics
  87. IMPLICATION OF TOLL-LIKE RECEPTOR AND TUMOR NECROSIS FACTOR α SIGNALING IN SEPTIC SHOCK
    Wen-Jye Lin, W. Yeh · 2005 · Shock
  88. Four N-linked Glycosylation Sites in Human Toll-like Receptor 2 Cooperate to Direct Efficient Biosynthesis and Secretion*
    A. Weber, M. Morse, N. Gay · 2004 · Journal of Biological Chemistry
  89. Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors.
    R. Ingalls, H. Heine, E. Lien, A. Yoshimura, D. Golenbock · 1999 · Infectious Disease Clinics of North America
  90. NF‐κB activation in melanoma
    Yukiko Ueda, Ann J. Richmond · 2006 · Pigment Cell Research
  91. Direct Phosphorylation of NF-κB1 p105 by the IκB Kinase Complex on Serine 927 Is Essential for Signal-induced p105 Proteolysis*
    A. Salmeron, J. Janzen, Y. Soneji, N. Bump, J. Kamens, H. Allen, S. Ley · 2001 · Journal of Biological Chemistry
  92. Current Trends in the Embryology of Angiosperms
    S. S. Bhojwani, W. Soh · 2001 · Springer Netherlands
  93. Toll-like Receptors and Innate Immunity
    Shizuo Akira · 2001 · Advances in immunology
  94. Vibrio fischeri lipopolysaccharide induces developmental apoptosis, but not complete morphogenesis, of the Euprymna scolopes symbiotic light organ.
    J. S. Foster, M. Apicella, M. McFall-Ngai · 2000 · Developmental Biology
  95. Oligomerisation of Tube and Pelle leads to nuclear localisation of dorsal.
    J. Grosshans, F. Schnorrer, C. Nüsslein-Volhard · 1999 · Mechanisms of Development
  96. Melanotic Mutants in Drosophila: Pathways and Phenotypes
    S. Minakhina, R. Steward · 2006 · Genetics
  97. Toll-like receptor regulation of effector T lymphocyte function
    Joseph M. Reynolds, Chen Dong · 2013 · Trends in Immunology
  98. Type I interferons and the innate immune response--more than just antiviral cytokines.
    P. Smith, G. Lombardi, G. Foster · 2005 · Molecular Immunology
  99. Up-regulation of TLR9 gene expression by LPS in mouse macrophages via activation of NF-kappaB, ERK and p38 MAPK signal pathways.
    Hua-Zhang An, Hong-Mei Xu, Yi-Zhi Yu, Ming-Hui Zhang, Run-Zi Qi, Xiaoyi Yan, Shu-Xun Liu, Wen-Ya Wang, Zhenghong Guo, Zhi-Hai Qin et al. · 2002 · Immunology Letters
  100. Modulation of γδ T cell responses by TLR ligands
    Daniela Wesch, Christian Peters, Hans‐Heinrich Oberg, Kathrin Pietschmann, Dieter Kabelitz · 2011 · Cellular and Molecular Life Sciences