The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.
Cross-Presentation, Dendritic Cells, Tolerance and Immunity
Abstract
This review examines the role of cross-presentation in tolerance and immunity. We discuss (a) the antigenic requirements for cross-presentation, (b) the phenotype of the antigen presenting cell (APC), (c) the cellular interactions and molecular signals involved in cross-priming, and (d) the factors that direct the immune system toward tolerance or immunity. A large part of this review is dedicated to summarizing our current knowledge of the cross-presenting APC.
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“Perhaps paradoxically, tolerance induction by apoptotic cells depends on MHC class I molecules and involves immune suppression by CD8+ T cells10,24,25.”
From Immunogenic and tolerogenic cell death (2009) · cites this paper as [25]
Citations
Cites
Dendritic cells and the control of immunity
Banchereau, J., & Steinman, R. M. (1998) · Nature · doi:10.1038/32588 · Cited by 14,496
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
Medzhitov, R., Preston-Hurlburt, P., & Janeway, C. A. J. (1997) · Nature · doi:10.1038/41131 · Cited by 6,137
Tolerance, Danger and the Extended Family
Matzinger, P. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.005015 · Cited by 5,107
T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions
Schoenberger, S. P., Toes, R. E. M., van der Voort, E. I. H., Offringa, R., & Melief, C. J. M. (1998) · Nature · doi:10.1038/31002 · Cited by 2,615
Sallusto, F., Cella, M., Danieli, C., & Lanzavecchia, A. (1995) · The Journal of Experimental Medicine · doi:10.1084/jem.182.2.389 · Cited by 2,501
IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE
Steinman, R. M., & Cohn, Z. A. (1973) · The Journal of Experimental Medicine · doi:10.1084/jem.137.5.1142 · Cited by 2,443
Innate Immunity: The Virtues of a Nonclonal System of Recognition
Medzhitov, R., & Janeway, C. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80412-2 · Cited by 2,434
A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
Ridge, J. P., Rosa, F. D., & Matzinger, P. (1998) · Nature · doi:10.1038/30989 · Cited by 2,360
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
Albert, M. L., Sauter, B., & Bhardwaj, N. (1998) · Nature · doi:10.1038/32183 · Cited by 2,350
Research works printed but not linked: 2
- Ansorge S, 1984, Biomed. Biochim. Acta, 43, 1213
- Miceli MV, 1999, Invest. Ophthalmol. Visual Sci., 40, 1238
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Metadata
- Authors
- Heath, W. R., & Carbone, F. R.
- Affiliations
- The Royal Melbourne Hospital (AU)
- Immunology Division, The Walter and Eliza Hall Institute, Post Office Royal Melbourne Hospital, Parkville, Victoria 3052, Australia;
- ORCID
- Heath, William R.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 2001-04
- Volume
- 19
- Issue
- 1
- Pages
- 47-64
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2107140931
- Cited by
- 882
- References
- 92
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 10 · 2023: 12 · 2022: 9 · 2021: 6 · 2020: 10 · 2019: 11 · 2018: 18 · 2017: 23 · 2016: 26 · 2015: 19 · 2014: 20 · 2013: 21 · 2012: 23
- FWCI
- 8.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Immunology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Keywords
- cross-presentation, dendritic cells, cross-priming, antigen presentation, immune tolerance, antigen-presenting cells, molecular signals
- MeSH terms
- Animals, Dendritic Cells, Histocompatibility Antigens, HLA Antigens, Humans, Immune Tolerance, Immunity, Macrophages, Mice, Transgenic, T-Lymphocyte Subsets, Antigen Presentation, Mice
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