Cross-Presentation, Dendritic Cells, Tolerance and Immunity

Dendritic cells and the control of immunity

Banchereau, J., & Steinman, R. M. (1998) · Nature · doi:10.1038/32588 · Cited by 14,486

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Medzhitov, R., Preston-Hurlburt, P., & Janeway, C. A. J. (1997) · Nature · doi:10.1038/41131 · Cited by 6,137

Tolerance, Danger, and the Extended Family

Matzinger, P. (1994) · Annual Review of Immunology · doi:10.1146/annurev.iy.12.040194.005015 · Cited by 4,848

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

Schoenberger, S. P., Toes, R. E. M., van der Voort, E. I. H., Offringa, R., & Melief, C. J. M. (1998) · Nature · doi:10.1038/31002 · Cited by 2,615

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

Sallusto, F., Cella, M., Danieli, C., & Lanzavecchia, A. (1995) · The Journal of Experimental Medicine · doi:10.1084/jem.182.2.389 · Cited by 2,501

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

Steinman, R. M., & Cohn, Z. A. (1973) · The Journal of Experimental Medicine · doi:10.1084/jem.137.5.1142 · Cited by 2,443

Innate Immunity: The Virtues of a Nonclonal System of Recognition

Medzhitov, R., & Janeway, C. A. (1997) · Cell · doi:10.1016/s0092-8674(00)80412-2 · Cited by 2,434

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

Ridge, J. P., Rosa, F. D., & Matzinger, P. (1998) · Nature · doi:10.1038/30989 · Cited by 2,360

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

Albert, M. L., Sauter, B., & Bhardwaj, N. (1998) · Nature · doi:10.1038/32183 · Cited by 2,350

Autoreactive CD8 T Cells in Organ-Specific Autoimmunity

Liblau, R., Wong, F. S., Mars, L. T., & Santamaría, P. (2002) · Immunity · doi:10.1016/s1074-7613(02)00338-2 · Cited by 206

The Role of OX40-Mediated Co-stimulation in T-Cell Activation and Survival

Redmond, W. L., Ruby, C. E., & Weinberg, A. D. (2009) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.v29.i3.10 · Cited by 205

Vaccination in Humans Generates Broad T Cell Cytokine Responses

Rosa, S. C. D., Lü, F. X.-S., Yu, J., Perfetto, S. P., Falloon, J., Moser, S., Evans, T. G., Koup, R. A., Miller, C. J., & Roederer, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.9.5372 · Cited by 204

Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory

Agarwal, P., Raghavan, A., Nandiwada, S. L., Curtsinger, J., Bohjanen, P. R., Mueller, D. L., & Mescher, M. F. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900592 · Cited by 203

Dendritic Cell Immunogenicity Is Regulated by Peroxisome Proliferator-Activated Receptor γ

Nencioni, A., Grünebach, F., Zobywlaski, A., Denzlinger, C., Brugger, W., & Brossart, P. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.3.1228 · Cited by 202

Vaccination with Plasmid DNA Activates Dendritic Cells via Toll-Like Receptor 9 (TLR9) but Functions in TLR9-Deficient Mice

Spies, B., Hochrein, H., Vabulas, M., Huster, K. M., Busch, D. H., Schmitz, F., Heit, A., & Wagner, H. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.11.5908 · Cited by 196

Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells

Goldberg, M. V., Maris, C. H., Hipkiss, E. L., Flies, A. S., Zhen, L., Tuder, R. M., Grosso, J. F., Harris, T., Getnet, D., Whartenby, K. A., et al. (2007) · Blood · doi:10.1182/blood-2006-12-062422 · Cited by 187

Uptake of Apoptotic Antigen-Coupled Cells by Lymphoid Dendritic Cells and Cross-Priming of CD8+ T Cells Produce Active Immune Unresponsiveness

Ferguson, T. A., Herndon, J. M., Elzey, B. D., Griffith, T. S., Schoenberger, S., & Green, D. R. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.11.5589 · Cited by 187

Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine

OʼRourke, M. G. E., Johnson, M. K., Lanagan, C. M., See, J. L., Yang, J., BELL, J. R., Slater, G. J., Kerr, B. M., Crowe, B., Purdie, D. M., et al. (2003) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-003-0375-x · Cited by 186

PPAR-γ agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-κB pathways

Appel, S., Mirakaj, V., Bringmann, A., Weck, M. M., Grünebach, F., & Brossart, P. (2005) · Blood · doi:10.1182/blood-2004-12-4709 · Cited by 185

Cellular protein is the source of cross-priming antigen in vivo

Shen, L., & Rock, K. L. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308345101 · Cited by 185

Viruses and their uses in nanotechnology

Singh, P. N. P., González, M. J., & Manchester, M. (2006) · Drug Development Research · doi:10.1002/ddr.20064 · Cited by 181

Immune Enhancement of Skin Carcinogenesis by CD4+ T Cells

Daniel, D., Meyer-Morse, N., Bergsland, E. K., Dehne, K., Coussens, L. M., & Hanahan, D. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20021047 · Cited by 180

Mini‐review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross‐priming and direct priming?

Melief, C. J. M. (2003) · European Journal of Immunology · doi:10.1002/eji.200324341 · Cited by 184

Enhancing DNA vaccine potency by coadministration of DNA encoding antiapoptotic proteins

Kim, T. W., Hung, C., Ling, M. F., Juang, J., He, L., Hardwick, J. M., Kumar, S., & Wu, T. ‐. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17293 · Cited by 179

Intratumoral Injection of Dendritic Cells Engineered to Secrete Interleukin-12 by Recombinant Adenovirus in Patients With Metastatic Gastrointestinal Carcinomas

Mazzolini, G. D., Alfaro, C., Sangro, B., Feijoó, E., Ruiz, J., Benito, A., Tirapu, I., Arina, A., Sola, J., Herráiz, M., et al. (2004) · Journal of Clinical Oncology · doi:10.1200/jco.2005.00.463 · Cited by 177

Regulation of Antigen Presentation and Cross-Presentation in the Dendritic Cell Network: Facts, Hypothesis, and Immunological Implications

Wilson, N. S., & Villadangos, J. A. (2005) · Advances in immunology · doi:10.1016/s0065-2776(04)86007-3 · Cited by 181

Induction of Tolerance and Immunity by Dendritic Cells: Mechanisms and Clinical Applications

Fucikova, J. P., Palová-Jelínková, L., Bartůňková, J., & Špíšek, R. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02393 · Cited by 177

Tracking the Total CD8 T Cell Response to Infection Reveals Substantial Discordance in Magnitude and Kinetics between Inbred and Outbred Hosts

Rai, D., Pham, N., Harty, J. T., & Badovinac, V. P. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0902874 · Cited by 170

The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia

Chakraverty, R. K., & Sykes, M. (2007) · Blood · doi:10.1182/blood-2006-12-022038 · Cited by 177

Human Dendritic Cells Produce TGF-β1 under the Influence of Lung Carcinoma Cells and Prime the Differentiation of CD4+CD25+Foxp3+ Regulatory T Cells

Dumitriu, I. E., Dunbar, D. R., Howie, S., Sethi, T., & Gregory, C. D. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0712671 · Cited by 171

T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells

Dhodapkar, M. V., Krasovsky, J., & Olson, K. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.202491499 · Cited by 170

The Role of Neutrophils and Monocytes in Innate Immunity

Kantari‐Mimoun, C., Pederzoli-Ribeil, M., & Witko‐Sarsat, V. (2008) · KARGER eBooks · doi:10.1159/000136335 · Cited by 177

Control of cross‐presentation during dendritic cell maturation

Gil-Torregrosa, B., Lennon‐Duménil, A., Kessler, B. M., Guermonprez, P., Ploegh, H. L., Fruci, D., Endert, P. V., & Amigorena, S. (2004) · European Journal of Immunology · doi:10.1002/eji.200324508 · Cited by 167

Harnessing human dendritic cell subsets for medicine

Ueno, H., Schmitt, N., Klechevsky, E., Pedroza‐González, A., Matsui, T., Zurawski, G., Oh, S., Fay, J. W., Pascual, V., Banchereau, J., et al. (2010) · Immunological Reviews · doi:10.1111/j.0105-2896.2009.00884.x · Cited by 172

Paraneoplastic neurological degenerations: keys to tumour immunity

Albert, M. L., & Darnell, R. B. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1255 · Cited by 173

Tumor-induced interleukin 10 suppresses the ability of splenic dendritic cells to stimulate CD4 and CD8 T-cell responses.

Yang, A. S., & Lattime, E. C. (2003) · PubMed · Cited by 165

Imatinib mesylate affects the development and function of dendritic cells generated from CD34+ peripheral blood progenitor cells

Appel, S., Boehmler, A. M., Grünebach, F., Müller, M., Rupf, A., Weck, M. M., Hartmann, U., Reichardt, V. L., Kanz, L., Brümmendorf, T. H., et al. (2003) · Blood · doi:10.1182/blood-2003-03-0975 · Cited by 163

Peripheral Deletion of Autoreactive CD8 T Cells by Cross Presentation of Self-Antigen Occurs by a Bcl-2–inhibitable Pathway Mediated by Bim

Davey, G. M., Kurts, C., Miller, J. F. A. P., Bouillet, P., Strasser, A., Brööks, A. G., Carbone, F., & Heath, W. R. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020827 · Cited by 165

Activation of Peroxisome Proliferator-Activated Receptor-γ in Dendritic Cells Inhibits the Development of Eosinophilic Airway Inflammation in a Mouse Model of Asthma

Hammad, H., de Heer, H. J., Soullié, T., Angéli, V., Trottein, F., Hoogsteden, H. C., & Lambrecht, B. N. (2004) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)63116-1 · Cited by 162

A New Subset of CD103+CD8α+ Dendritic Cells in the Small Intestine Expresses TLR3, TLR7, and TLR9 and Induces Th1 Response and CTL Activity

Fujimoto, K., Karuppuchamy, T., Takemura, N., Shimohigoshi, M., MACHIDA, T., Haseda, Y., Aoshi, T., Ishii, K. J., Akira, S., & Uematsu, S. (2011) · The Journal of Immunology · doi:10.4049/jimmunol.1004036 · Cited by 159

B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections

Joshi, T., Rodriguez, S., Perović, V., Cockburn, I. A., & Stäger, S. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000431 · Cited by 153

Recognition of a New ARTC1 Peptide Ligand Uniquely Expressed in Tumor Cells by Antigen-Specific CD4+ Regulatory T Cells

Wang, H. Y., Peng, G., Guo, Z., Shevach, E. M., & Wang, R. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.5.2661 · Cited by 157

Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection

Tamburini, B. A., Burchill, M. A., & Kedl, R. M. (2014) · Nature Communications · doi:10.1038/ncomms4989 · Cited by 153

Design and development of synthetic peptide vaccines: past, present and future

Bijker, M. S., Melief, C. J. M., Offringa, R., & van der Burg, S. H. (2007) · Expert Review of Vaccines · doi:10.1586/14760584.6.4.591 · Cited by 152

Dendritic Cells Cross-Dressed with Peptide MHC Class I Complexes Prime CD8+ T Cells

Dolan, B. P., Gibbs, K. D., & Ostrand‐Rosenberg, S. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.9.6018 · Cited by 152

Caspase-3-Dependent β-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus

Liadis, N., Murakami, K., Eweida, M., Elford, A. R., Sheu, L., Gaisano, H. Y., Hakem, R., Ohashi, P. S., & Woo, M. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.9.3620-3629.2005 · Cited by 152

Poly-l-lysine-coated nanoparticles: A potent delivery system to enhance DNA vaccine efficacy

Minigo, G., Scholzen, A., Tang, C. K., Hanley, J. C., Kalkanidis, M., Pietersz, G. A., Apostolopoulos, V., & Plebanski, M. (2006) · Vaccine · doi:10.1016/j.vaccine.2006.09.086 · Cited by 151

Heat shock protein 90 (HSP90) contributes to cytosolic translocation of extracellular antigen for cross-presentation by dendritic cells

Imai, T., Kato, Y., Kajiwara, C., Mizukami, S., Ishige, I., Ichiyanagi, T., Hikida, M., Wang, J. O., & Udono, H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1108372108 · Cited by 150

T-cell signalling and autoimmunity: molecular mechanisms of disease

Ohashi, P. S. (2002) · Nature reviews. Immunology · doi:10.1038/nri822 · Cited by 148

A cytosolic pathway for MHC class II–restricted antigen processing that is proteasome and TAP dependent

Tewari, M. K., Sinnathamby, G., Rajagopal, D., & Eisenlohr, L. C. (2005) · Nature Immunology · doi:10.1038/ni1171 · Cited by 149

Evidence for the Presentation of Major Histocompatibility Complex Class I–restricted Epstein-Barr Virus Nuclear Antigen 1 Peptides to CD8+ T Lymphocytes

Voo, K. S., Fu, T., Wang, H. Y., Tellam, J., Heslop, H. E., Brenner, M. K., Rooney, C. M., & Wang, R. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20031219 · Cited by 149

Interactions of tumor cells with dendritic cells: balancing immunity and tolerance

Dhodapkar, M. V., Dhodapkar, K. M., & Palucka, A. K. (2007) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402247 · Cited by 154

Recombinant HIV-1 Pr55gag virus-like particles: potent stimulators of innate and acquired immune responses

Deml, L., Speth, C., Dierich, M. P., Wolf, H. J., & Wagner, R. (2004) · Molecular Immunology · doi:10.1016/j.molimm.2004.06.028 · Cited by 142

Dysfunction of antigen processing and presentation by dendritic cells in cancer

Bandola-Simon, J. M., & Roche, P. A. (2018) · Molecular Immunology · doi:10.1016/j.molimm.2018.03.025 · Cited by 142

CpG-DNA Aided Cross-Priming by Cross-Presenting B Cells

Heit, A., Huster, K. M., Schmitz, F., Schiemann, M., Busch, D. H., & Wagner, H. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.3.1501 · Cited by 141

The Trypanosoma cruzi Tc52-Released Protein Induces Human Dendritic Cell Maturation, Signals Via Toll-Like Receptor 2, and Confers Protection Against Lethal Infection

Ouaissi, A., Guilvard, E., Delneste, Y., Caron, G., Magistrelli, G., Herbault, N., Thiéblemont, N., & Jeannin, P. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.12.6366 · Cited by 141

Chapter 4 CD8+ T Cells in Type 1 Diabetes

Tsai, S., Shameli, A., & Santamaria, P. (2008) · Advances in Immunology · doi:10.1016/s0065-2776(08)00804-3 · Cited by 140

Tumor-Derived Autophagosome Vaccine: Mechanism of Cross-Presentation and Therapeutic Efficacy

Li, Y., Wang, L., Pang, P., Cui, Z.-H., Aung, S., Haley, D. P., Fox, B. A., Urba, W. J., & Hu, H. (2011) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-11-0951 · Cited by 144

Cutting Edge: Programed Death (PD) Ligand-1/PD-1 Interaction Is Required for CD8+ T Cell Tolerance to Tissue Antigens

Martín‐Orozco, N., Wang, Y.-H., Yagita∥, H., & Dong, C. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.12.8291 · Cited by 142

An innately interesting decade of research in immunology

Germain, R. N. (2004) · Nature Medicine · doi:10.1038/nm1159 · Cited by 136

Differential Effects of Dengue Virus on Infected and Bystander Dendritic Cells

Palmer, D. R., Sun, P., Celluzzi, C. M., Bisbing, J., Pang, S., Sun, W., Marovich, M., & Burgess, T. H. (2005) · Journal of Virology · doi:10.1128/jvi.79.4.2432-2439.2005 · Cited by 136

The role of dendritic cell C-type lectin receptors in HIV pathogenesis

Turville, S. G., Wilkinson, J. C., Cameron, P. U., Dable, J., & Cunningham, A. L. (2003) · Journal of Leukocyte Biology · doi:10.1189/jlb.0503208 · Cited by 142

Uncoupling of Proliferative Potential and Gain of Effector Function by CD8+ T Cells Responding to Self-Antigens

Hernández, J., Aung, S., Marquardt, K., & Sherman, L. A. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011612 · Cited by 133

Characterization of the MHC class I cross-presentation pathway for cell-associated antigens by human dendritic cells

Fonteneau, J., Kavanagh, D. G., Lirvall, M., Sanders, C. J., Cover, T. L., Bhardwaj, N., & Larsson, M. (2003) · Blood · doi:10.1182/blood-2003-06-1801 · Cited by 131

Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

Luckashenak, N. A., Schroeder, S., Endt, K., Schmidt, D., Mahnke, K., Bachmann, M., Marconi, P., Deeg, C., & Brocker, T. (2008) · Immunity · doi:10.1016/j.immuni.2008.02.018 · Cited by 151

Immune Response Against Dying Tumor Cells

Zitvogel, L., Casares, N., Péquignot, M. O., Chaput, N., Albert, M. L., & Kroemer, G. (2004) · Advances in immunology · doi:10.1016/s0065-2776(04)84004-5 · Cited by 137

CD8α2 CD11b+ Dendritic Cells Present Exogenous Virus-like Particles to CD8+ T Cells and Subsequently Express CD8α and CD205 Molecules

Morón, G., Rueda, P., Casal, J. I., & Leclerc, C. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011930 · Cited by 129

Spontaneous Protein Adsorption on Graphene Oxide Nanosheets Allowing Efficient Intracellular Vaccine Protein Delivery

Li, H., Fierens, K., Zhang, Z., Vanparijs, N., Schuijs, M. J., Steendam, K. V., Feiner‐Gracia, N., Rycke, R. M. D., Beer, T. D., Beuckelaer, A. D., et al. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b08963 · Cited by 128

Tumor Growth Enhances Cross-Presentation Leading to Limited T Cell Activation without Tolerance

Nguyen, L. T., Elford, A. R., Murakami, K., Garza, K. M., Schoenberger, S. P., Odermatt, B., Speiser, D. E., & Ohashi, P. S. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20010032 · Cited by 128

Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?

Huber, A., Dammeijer, F. F., Aerts, J. G. J. V., & Vroman, H. H. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02804 · Cited by 128

Peptide Antigen Priming of Naive, But Not Memory, CD8 T Cells Requires a Third Signal That Can Be Provided by IL-12

Schmidt, C. S., & Mescher, M. F. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.11.5521 · Cited by 123

Fcγ Receptors and Cross-Presentation in Dendritic Cells

Amigorena, S. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011925 · Cited by 126

Intestinal Tolerance Is Converted to Autoimmune Enteritis upon PD-1 Ligand Blockade

Reynoso, E. D., Elpek, K. G., Francisco, L. M., Bronson, R. T., Bellemare‐Pelletier, A., Sharpe, A. H., Freeman, G. J., & Turley, S. J. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0802769 · Cited by 126

Plasmacytoid Dendritic Cell Precursors Induce Allogeneic T‐Cell Hyporesponsiveness and Prolong Heart Graft Survival

Abe, M., Wang, Z., Creus, A. D., & Thomson, A. W. (2005) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2005.00954.x · Cited by 125

Human papillomavirus molecular biology and pathogenesis

Sanclemente, G., & Gill, D. (2002) · Journal of the European Academy of Dermatology and Venereology · doi:10.1046/j.1473-2165.2002.00419.x · Cited by 123

Peroxisome Proliferator-Activated Receptor γ Control of Dendritic Cell Function Contributes to Development of CD4+ T Cell Anergy

Klotz, L., Dani, I., Edenhofer, F., Nolden, L., Evert, B. O., Paul, B., Kolanus, W., Klockgether, T., Knolle, P. A., & Diehl, L. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.4.2122 · Cited by 123

Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer

Castelli, C., Rivoltini, L., Rini, F., Belli, F., Testori, A., Maio, M., Mazzaferro, V., Coppa, J. C., Srivastava, P. K., & Parmiani, G. (2004) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-003-0481-9 · Cited by 122

The role of IFN-γ in tumor transplantation immunity and inhibition of chemical carcinogenesis

Blankenstein, T. J. F., & Qin, Z. (2003) · Current Opinion in Immunology · doi:10.1016/s0952-7915(03)00007-4 · Cited by 122

CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses

Castro, F., Tutt, A. L., White, A. L., Teeling, J. L., James, S., French, R. R., & Glennie, M. J. (2008) · European Journal of Immunology · doi:10.1002/eji.200838302 · Cited by 120

Targeting glycan modified OVA to murine DC-SIGN transgenic dendritic cells enhances MHC class I and II presentation

Singh, S., Stephani, J., Schaefer, M., Kalay, H., García-Vallejo, J. J., den Haan, J. M. M., Saeland, E., Sparwasser, T. D., & van Kooyk, Y. (2009) · Molecular Immunology · doi:10.1016/j.molimm.2009.09.026 · Cited by 119

Hollow Mesoporous Silica Nanoparticles with Extra-Large Mesopores for Enhanced Cancer Vaccine

Lee, J. Y., Kim, M. K., Nguyen, T. L., & Kim, J. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c09484 · Cited by 119

Improved peptide vaccine strategies, creating synthetic artificial infections to maximize immune efficacy

van der Burg, S. H., Bijker, M. S., Welters, M. J. P., Offringa, R., & Melief, C. J. M. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2005.11.003 · Cited by 119

Langerhans Cells Activate Naive Self-Antigen-Specific CD8 T Cells in the Steady State

Mayerova, D., Parke, E. A., Bursch, L. S., Odumade, O. A., & Hogquist, K. A. (2004) · Immunity · doi:10.1016/j.immuni.2004.07.019 · Cited by 119

Expression of the Epstein-Barr virus nuclear antigen-1 (EBNA-1) in the mouse can elicit the production of anti-dsDNA and anti-Sm antibodies

Sundar, K., Jacques, S., Gottlieb, P., Villars, R., Benito, M.-E., Taylor, D. K., & Spatz, L. A. (2004) · Journal of Autoimmunity · doi:10.1016/j.jaut.2004.06.001 · Cited by 119

Danger signals: a time and space continuum

Škoberne, M., Beignon, A., & Bhardwaj, N. (2004) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2004.04.001 · Cited by 118

Epigenetic regulation of immune escape genes in cancer

Tomasi, T. B., Magner, W. J., & Khan, A. N. H. (2006) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-006-0164-4 · Cited by 119

Immature and Mature CD8α+ Dendritic Cells Prolong the Survival of Vascularized Heart Allografts

O’Connell, P. J., Li, W., Wang, Z., Specht, S. M., Logar, A., & Thomson, A. W. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.1.143 · Cited by 118

Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells

Lee, Y.-R., Yang, I.-H., Lee, Y., Im, S., Song, S., Li, H., Han, K., Kim, K., Eo, S. K., & Lee, C. (2005) · Blood · doi:10.1182/blood-2004-10-3927 · Cited by 115

Sustained and Complete Phenotype Correction of Hemophilia B Mice Following Intramuscular Injection of AAV1 Serotype Vectors

Chao, H., Monahan, P. E., Liu, Y., Samulski, R. J., & Walsh, C. (2001) · Molecular Therapy · doi:10.1006/mthe.2001.0449 · Cited by 115

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Ramakrishna, V., Treml, J., Vitale, L. A., Connolly, J. E., O’Neill, T. J., Smith, P. A., Jones, C. L., He, L.-Z., Goldstein, J., Wallace, P. K., et al. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.5.2845 · Cited by 114

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Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen

Hochweller, K., Wabnitz, G. H., Samstag, Y., Suffner, J., Hämmerling, G. J., & Garbi, N. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911877107 · Cited by 113

Immunity or tolerance? That is the question for dendritic cells

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Melief, C. J. M., van der Burg, S. H., Toes, R. E. M., OSSENDORP, F. A., & Offringa, R. (2002) · Immunological Reviews · doi:10.1034/j.1600-065x.2002.18816.x · Cited by 111

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Morón, V. G., Rueda, P., Sedlik, C., & Leclerc, C. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.5.2242 · Cited by 111

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Moehler, M. H., Zeidler, M., Wilsberg, V., Cornelis, J. J., Woelfel, T., Rommelaere, J., Galle, P. R., & Heike, M. (2005) · Human Gene Therapy · doi:10.1089/hum.2005.16.996 · Cited by 110

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Gereke, M., Jung, S., Buer, J., & Bruder, D. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200804-592oc · Cited by 113

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Ferguson, T. A., Choi, J., & Green, D. R. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01006.x · Cited by 118

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Pinto, A. K., Daffis, S., Brien, J. D., Gainey, M. D., Yokoyama, W. M., Sheehan, K. C. F., MURPHY, K. M. M., Schreiber, R. D., & Diamond, M. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002407 · Cited by 107

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Bayry, J., Lacroix‐Desmazes, S., Donkova-Petrini, V., Carbonneil, C., Misra, N., Lepelletier, Y., Delignat, S., Varambally, S., Oksenhendler, É., Lévy, Y., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402183101 · Cited by 104

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Murshid, A., Gong, J., Stevenson, M. A., & Calderwood, S. K. (2011) · Expert Review of Vaccines · doi:10.1586/erv.11.124 · Cited by 105

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Melzer, N., Meuth, S. G., & Wiendl, H. (2009) · The FASEB Journal · doi:10.1096/fj.09-136200 · Cited by 105

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Imai, J., Hasegawa, H., Maruya, M., Koyasu, S., & Yahara, I. (2004) · International Immunology · doi:10.1093/intimm/dxh184 · Cited by 103

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Gubbels, M., Striepen, B., Shastri, N., Turkoz, M., & Robey, E. A. (2005) · Infection and Immunity · doi:10.1128/iai.73.2.703-711.2005 · Cited by 103

Cross-presentation by dendritic cells

Joffre, O. P., Segura, É., Savina, A., & Amigorena, S. (2012) · Nature reviews. Immunology · doi:10.1038/nri3254 · Cited by 1,764

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Wilson, N. S., & Villadangos, J. A. (2005) · Advances in immunology · doi:10.1016/s0065-2776(04)86007-3 · Cited by 181

Cross‐presentation: underlying mechanisms and role in immune surveillance

Rock, K. L., & Shen, L. (2005) · Immunological Reviews · doi:10.1111/j.0105-2896.2005.00301.x · Cited by 469

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