The DOI matches its Crossref record, with a small difference in title or year; 55 of the 55 references it cites were found in a registry or an index.
CIRCADIAN RHYTHMS: Basic Neurobiology and Clinical Applications
Abstract
▪ Abstract Circadian rhythms are major features of adaptation to our environment. In mammals, circadian rhythms are generated and regulated by a circadian timing system. This system consists of entrainment pathways, pacemakers, and pacemaker output to effector systems that are under circadian control. The primary entrainment pathway is the retinohypothalamic tract, which terminates in the circadian pacemakers, the suprachiasmatic nuclei of the hypothalamus. The output of the suprachiasmatic nuclei is principally to the hypothalamus, the midline thalamus, and the basal forebrain. This provides a temporal organization to the sleep-wake cycle, to many physiological and endocrine functions, and to psychomotor performance functions. Disorders of circadian timing primarily affect entrainment and pacemaker functions. The pineal hormone, melatonin, appears to be a promising agent for therapy of some circadian timing disorders.
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Transplanted Suprachiasmatic Nucleus Determines Circadian Period
Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853
Welsh, D. K., Logothetis, D. E., Meister, M., & Reppert, S. M. (1995) · Neuron · doi:10.1016/0896-6273(95)90214-7 · Cited by 1,481
A retinohypothalamic projection in the rat
Moore, R. Y., & Lenn, N. J. (1972) · The Journal of Comparative Neurology · doi:10.1002/cne.901460102 · Cited by 1,263
Inouye, S. T., & Kawamura, H. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.11.5962 · Cited by 985
The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia
Swaab, D. F., Fliers, E., & Partiman, T. S. (1985) · Brain Research · doi:10.1016/0006-8993(85)91350-2 · Cited by 847
Melatonin and the Mammalian Pineal Gland
Arendt, J. (1994) · Cited by 788
Neurophysiology of the suprachiasmatic circadian pacemaker in rodents
Meijer, J. H., & Rietveld, W. J. (1989) · Physiological Reviews · doi:10.1152/physrev.1989.69.3.671 · Cited by 737
Circadian Rhythms in Cultured Mammalian Retina
Tosini, G., & Menaker, M. (1996) · Science · doi:10.1126/science.272.5260.419 · Cited by 716
Melatonin Shifts Human Orcadian Rhythms According to a Phase-Response Curve
Lewy, A. J., Ahmed, S., Jackson, J. M. L., & Sack, R. L. (1992) · Chronobiology International · doi:10.3109/07420529209064550 · Cited by 693
Suppression of Melatonin Secretion in Some Blind Patients by Exposure to Bright Light
Czeisler, C. A., Shanahan, T. L., Klerman, E. B., Martens, H., Brotman, D. J., Emens, J. S., Klein, T., & Rizzo, J. F. (1995) · New England Journal of Medicine · doi:10.1056/nejm199501053320102 · Cited by 654
Research works printed but not linked: 11
- Minors DS, 1992, Neurosci. Lett., 13, 36
- Van Cauter E, 1993, J. Biol. Rhythms, 8, S99
- Moore RY, 1978, J. Neural. Trans., 13, 47
- Speh JC, 1995, Soc. Neurosci., 21, 179
- Watts AG. 1991. The efferent projections of the suprachiasmatic nucleus: anatomical insights into the control of circadian rhythms. InThe Suprachiasmatic Nucleus—The Mind's Clock, ed. DC Klein, RY Moore, ST Reppert, pp. 77–106. New York:Oxford
- Graeber RC. 1994. Jet lag and sleep disruption. InPrinciples and Practice of Sleep Medicine, ed. MH Kryger, T Roth, WC Dement, pp. 463–70. New York: Saunders
- Monk TH. 1994. Shift work. InPrinciples and Practice of Sleep Medicine, ed. MH Kryger, T Roth, WC Dement, pp. 471–76. New York: Saunders
- Wagner DR. 1990. Circadian rhythm sleep disorders. InHandbook of Sleep Disorders, ed. M Thorpy, pp. 493–52. New York: Dekker
- Roehrs T, Roth T. 1994. Chronic insomnias associated with circadian rhythm disorders. InPrinciples and Practice of Sleep Medicine, ed. MH Kryger, T Roth, WC Dement, pp. 447–81. New York: Saunders
- Prinz PN, 1984, J. G erontol., 39, 30
- Wirz-Justice A. 1995. Biological rhythms in mood disorders. InPsychopharmacology: The Fourth Generation of Progress, ed. FE Bloom, DJ Kupfer, pp. 999–1017. New York: Raven
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Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329
Sleep Patterns and Predictors of Disturbed Sleep in a Large Population of College Students
Lund, H. G., Reider, B. D., Whiting, A. B., & Prichard, J. R. (2010) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2009.06.016 · Cited by 1,907
Mop3 is an essential component of the master circadian pacemaker in mammals.
Bunger, M. K., Wilsbacher, L. D., Moran, S. M., Clendenin, C., Radcliffe, L. A., Hogenesch, J. B., Simon, M. C., Takahashi, J. S., & Bradfield, C. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00205-1 · Cited by 1,621
Molecular analysis of mammalian circadian rhythms
Reppert, S. M., & Weaver, D. R. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.647 · Cited by 1,444
Sleep, circadian rhythms, and delayed phase in adolescence
Crowley, S. J., Acebo, C., & Carskadon, M. A. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2006.12.002 · Cited by 1,127
Metadata
- Authors
- Moore MD, R. Y.
- Affiliations
- Departments of Psychiatry, Neurology, and Neuroscience, Center for Neuroscience and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania 15621
- Venue
- Annual Review of Medicine
- Publisher
- Annual Reviews
- Published
- 1997-02
- Volume
- 48
- Issue
- 1
- Pages
- 253-266
- ISSN
- 0066-4219 (ISSN-L)
- 1545-326X
- OpenAlex
- W2027654356
- Cited by
- 400
- References
- 55
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 12 · 2023: 8 · 2022: 6 · 2021: 16 · 2020: 12 · 2019: 10 · 2018: 20 · 2017: 16 · 2016: 15 · 2015: 8 · 2014: 10 · 2013: 13 · 2012: 19
- FWCI
- 1.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- circadian rhythm, circadian system, suprachiasmatic nucleus, retinohypothalamic tract, circadian pacemaker, sleep-wake cycle, melatonin, circadian rhythm disorders, chronobiology, hormonal regulation, psychomotor performance
- MeSH terms
- Animals, Brain, Brain Mapping, Circadian Rhythm, Humans, Hypothalamus, Neural Pathways, Retina, Sleep Stages, Suprachiasmatic Nucleus, Thalamus, Wakefulness, Prosencephalon
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