The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index.
Multiple Sclerosis
Abstract
▪ Abstract Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system (CNS). Diagnosis rests upon identifying typical clinical symptoms and interpreting supportive laboratory and radiological investigations. The etiology is unknown; however, strong evidence suggests that MS is an autoimmune disease directed against CNS myelin or oligodendrocytes. Genetic factors are important in the development of MS. Contributing environmental determinants (possibly including infectious agents) appear important but remain unidentified. Both cell-mediated and humorally mediated immune mechanisms contribute to pathological injury. Axonal damage occurs in addition to demyelination and may be the cause of later permanent disability. Distinct pathological subtypes may differentiate among patients with MS. Treatment is directed at acute attacks (with corticosteroids) and reduction of attack frequency (primarily with type-1 β interferons and glatiramer acetate). Research into the causes and treatments of MS has expanded our knowledge of this disease and promises improved care for MS patients in the future.
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Cites
New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
Poser, C. M., Paty, D. W., Scheinberg, L., McDonald, W. I., Davis, F. A., Ebers, G. C., Johnson, K. P., Sibley, W. A., Silberberg, D. H., & Tourtellotte, W. W. (1983) · Annals of Neurology · doi:10.1002/ana.410130302 · Cited by 7,384
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Axonal transection in the lesions of multiple sclerosis
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Defining the clinical course of multiple sclerosis: Results of an international survey
Lublin, F. D., Reingold, S. C., & National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis* (1996) · Neurology · doi:10.1212/wnl.46.4.907 · Cited by 3,686
Intramuscular interferon beta‐1a for disease progression in relapsing multiple sclerosis
Jacobs, L. D., Cookfair, D. L., Rudick, R. A., Herndon, R. M., Richert, J. R., Salazar, A. M., Fischer, J. S., Goodkin, D. E., Granger, C. V., Simon, J. H., et al. (1996) · Annals of Neurology · doi:10.1002/ana.410390304 · Cited by 2,450
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The clinical course of neuromyelitis optica (Devic’s syndrome)
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Cited by
Genetics of multiple sclerosis
Dyment, D. A., Ebers, G. C., & Dessa Sadovnick, A. (2004) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00663-x · Cited by 563
The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy
Gaeta, A., & Hider, R. C. (2005) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706416 · Cited by 411
Magnetic Resonance Imaging of Myelin
Laule, C., Vavasour, I. M., Kolind, S. H., Li, D. K. B., Traboulsee, T. L., Moore, G. R. W., & MacKay, A. L. (2007) · Neurotherapeutics · doi:10.1016/j.nurt.2007.05.004 · Cited by 334
Characterizing iron deposition in multiple sclerosis lesions using susceptibility weighted imaging
Haacke, E. M., Makki, M., Ge, Y., Maheshwari, M., Sehgal, V., Hu, J., Selvan, M., Wu, Z., Latif, Z., Xuan, Y., et al. (2009) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.21676 · Cited by 329
Gangliosides in the Brain: Physiology, Pathophysiology and Therapeutic Applications
Sipione, S., Monyror, J., Galleguillos, D., Steinberg, N., & Kadam, V. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.572965 · Cited by 325
Metadata
- Authors
- Keegan, B. M., & Noseworthy, J. H.
- Venue
- Annual Review of Medicine
- Publisher
- Annual Reviews
- Published
- 2002-02
- Volume
- 53
- Issue
- 1
- Pages
- 285-302
- ISSN
- 0066-4219 (ISSN-L)
- 1545-326X
- OpenAlex
- W4230052474
- Cited by
- 319
- References
- 80
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- closed
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- Keegan, B. M., & Noseworthy, J. H. (2002). Multiple Sclerosis. Annual Review of Medicine. https://doi.org/10.1146/annurev.med.53.082901.103909
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
