Persister Cells

Bacterial Biofilms: A Common Cause of Persistent Infections

Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167

Antimicrobial peptides of multicellular organisms

Zasloff, M. (2002) · Nature · doi:10.1038/415389a · Cited by 8,457

Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection

Baba, T., Ara, T., Hasegawa, M., Takai, Y., Okumura, Y., Baba, M., Datsenko, K. A., Tomita, M., Wanner, B. L., & Mori, H. (2006) · Molecular Systems Biology · doi:10.1038/msb4100050 · Cited by 7,858

Antibiotic resistance of bacteria in biofilms

Stewart, P. S., & Costerton, J. W. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05321-1 · Cited by 4,596

Antibacterial resistance worldwide: causes, challenges and responses

Levy, S. B., & Marshall, B. M. (2004) · Nature Medicine · doi:10.1038/nm1145 · Cited by 4,152

A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics

Kohanski, M. A., Dwyer, D. J., Hayete, B., Lawrence, C. A., & Collins, J. J. (2007) · Cell · doi:10.1016/j.cell.2007.06.049 · Cited by 2,982

Bacterial Persistence as a Phenotypic Switch

Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L., & Leibler, S. (2004) · Science · doi:10.1126/science.1099390 · Cited by 2,952

Stochasticity in gene expression: from theories to phenotypes

Kærn, M., Elston, T. C., Blake, W. J., & Collins, J. J. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1615 · Cited by 2,318

Chemotaxis in Escherichia coli analysed by Three-dimensional Tracking

Berg, H. C., & Brown, D. A. (1972) · Nature · doi:10.1038/239500a0 · Cited by 2,239

Persister cells, dormancy and infectious disease

Lewis, K. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1557 · Cited by 2,052

Biofilm formation to inhibition: Role of zinc oxide-based nanoparticles

Mahamuni-Badiger, P. P., Patil, P. M., Badiger, M. V., Patel, P. R., Gadgil, B. S. T., Pandit, A. S., & Bohara, R. A. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.110319 · Cited by 277

Recent insights into Candida albicans biofilm resistance mechanisms

Mathé, L., & Van Dijck, P. (2013) · Current Genetics · doi:10.1007/s00294-013-0400-3 · Cited by 271

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

den Bergh, B. V., Michiels, J. E., Wenseleers, T., Windels, E. M., Boer, P. V., Kestemont, D., Meester, L. D., Verstrepen, K. J., Verstraeten, N., Fauvart, M., et al. (2016) · Nature Microbiology · doi:10.1038/nmicrobiol.2016.20 · Cited by 271

Infection microenvironment-related antibacterial nanotherapeutic strategies

Wang, Z., Liu, X., Duan, Y., & Huang, Y. P. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121249 · Cited by 271

Candida glabrata: A review of its features and resistance

Rodrigues, C. F., Silva, S., & Henriques, M. (2014) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-013-2009-3 · Cited by 268

Strategy to combat biofilms: a focus on biofilm dispersal enzymes

Wang, S., Zhao, Y., Breslawec, A. P., Liang, T., Deng, Z., Kuperman, L. L., & Yu, Q. (2023) · npj Biofilms and Microbiomes · doi:10.1038/s41522-023-00427-y · Cited by 265

Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis

Sala, A. J., Bordes, P., & Genevaux, P. (2014) · Toxins · doi:10.3390/toxins6031002 · Cited by 264

A problem of persistence: still more questions than answers?

Balaban, N. Q., Gerdes, K., Lewis, K., & McKinney, J. D. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3076 · Cited by 263

The Role of Bacterial Biofilms in Device-Associated Infection

Deva, A. K., Adams, W. P., & Vickery, K. (2013) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0b013e3182a3c105 · Cited by 263

HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase

Kaspy, I., Rotem, E., Mosheiff, N., Ronin, I., Balaban, N. Q., & Glaser, G. (2013) · Nature Communications · doi:10.1038/ncomms4001 · Cited by 263

Mechanism of copper surface toxicity in Escherichia coli O157:H7 and Salmonella involves immediate membrane depolarization followed by slower rate of DNA destruction which differs from that observed for Gram‐positive bacteria

Warnes, S. L., Caves, V., & Keevil, C. W. (2011) · Environmental Microbiology · doi:10.1111/j.1462-2920.2011.02677.x · Cited by 261

Starvation, Together with the SOS Response, Mediates High Biofilm-Specific Tolerance to the Fluoroquinolone Ofloxacin

Bernier, S. P., Lebeaux, D., DeFrancesco, A. S., Valomon, A., Soubigou, G., Coppée, J., Ghigo, J., & Beloin, C. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003144 · Cited by 283

The role of metabolism in bacterial persistence

Amato, S. M., Fazen, C. H., Henry, T. C., Mok, W. W. K., Orman, M. A., Sandvik, E. L., Volzing, K., & Brynildsen, M. P. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00070 · Cited by 269

Dormancy Is Not Necessary or Sufficient for Bacterial Persistence

Orman, M. A., & Brynildsen, M. P. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00243-13 · Cited by 254

Structural basis of Staphylococcus epidermidis biofilm formation: mechanisms and molecular interactions

Büttner, H., Mack, D., & Rohde, H. (2015) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2015.00014 · Cited by 261

Phage-Encoded Endolysins

Abdelrahman, F. I., Easwaran, M., Daramola, O. I., Ragab, S., Lynch, S. A., Oduselu, T. J., Khan, F. M., Ayobami, A., Adnan, F., Torrents, E., et al. (2021) · Antibiotics · doi:10.3390/antibiotics10020124 · Cited by 250

Viable but nonculturable (VBNC) state, an underestimated and controversial microbial survival strategy

Liu, J., Yang, L., Kjellerup, B. V., & Xu, Z. (2023) · Trends in Microbiology · doi:10.1016/j.tim.2023.04.009 · Cited by 247

Options and Limitations in Clinical Investigation of Bacterial Biofilms

Magana, M., Sereti, C., Ioannidis, A., Mitchell, C. A., Ball, A. R., Magiorkinis, E., Chatzipanagiotou, S., Hamblin, M. R., Hadjifrangiskou, M., & Tegos, G. P. (2018) · Clinical Microbiology Reviews · doi:10.1128/cmr.00084-16 · Cited by 259

Phenotypic bistability in Escherichia coli's central carbon metabolism

Kotte, O., Volkmer, B., Radzikowski, J. L., & Heinemann, M. (2014) · Molecular Systems Biology · doi:10.15252/msb.20135022 · Cited by 242

Interaction of Candida albicans with host cells: virulence factors, host defense, escape strategies, and the microbiota

Hoefs, S., Mogavero, S., & Hube, B. (2016) · The Journal of Microbiology · doi:10.1007/s12275-016-5514-0 · Cited by 251

Fungal Biofilms and Polymicrobial Diseases

Costa-Orlandi, C. B., Sardi, J. D. C. O., Pitangui, N. D. S., de Oliveira, H. C., Scorzoni, L., Galeane, M. C., Medina‐Alarcón, K. P., Melo, W., Marcelino, M., Braz, J. D., et al. (2017) · Journal of Fungi · doi:10.3390/jof3020022 · Cited by 247

Vibrio cholerae Triggers SOS and Mutagenesis in Response to a Wide Range of Antibiotics: a Route towards Multiresistance

Baharoglu, Z., & Mazel, D. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01549-10 · Cited by 234

Methicillin Resistant Staphylococcus aureus: Molecular Mechanisms Underlying Drug Resistance Development and Novel Strategies to Combat

Abebe, A. A., & Birhanu, A. (2023) · Infection and Drug Resistance · doi:10.2147/idr.s428103 · Cited by 242

Stress responses as determinants of antimicrobial resistance in Gram-negative bacteria

Poole, K. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.02.004 · Cited by 237

Persisters, persistent infections and the Yin–Yang model

Zhang, Y. (2014) · Emerging Microbes & Infections · doi:10.1038/emi.2014.3 · Cited by 234

HipBA–promoter structures reveal the basis of heritable multidrug tolerance

Schumacher, M. A., Balani, P., Min, J., Chinnam, N. B., Hansen, S., Vulić, M., Lewis, K., & Brennan, R. G. (2015) · Nature · doi:10.1038/nature14662 · Cited by 243

Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells

Harms, A., Fino, C., Sørensen, M. A., Semsey, S., & Gerdes, K. (2017) · mBio · doi:10.1128/mbio.01964-17 · Cited by 229

Bacterial Heterogeneity and Antibiotic Survival: Understanding and Combatting Persistence and Heteroresistance

Dewachter, L., Fauvart, M., & Michiels, J. J. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.09.028 · Cited by 236

Pseudomonas aeruginosa Biofilm Infections: Community Structure, Antimicrobial Tolerance and Immune Response

Rybtke, M., Hultqvist, L. D., Givskov, M., & Tolker‐Nielsen, T. (2015) · Journal of Molecular Biology · doi:10.1016/j.jmb.2015.08.016 · Cited by 227

Staphylococcus aureus chronic and relapsing infections: Evidence of a role for persister cells

Conlon, B. P. (2014) · BioEssays · doi:10.1002/bies.201400080 · Cited by 224

Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics

Defraine, V., Fauvart, M., & Michiels, J. (2018) · Drug Resistance Updates · doi:10.1016/j.drup.2018.03.002 · Cited by 222

Intrinsic, adaptive and acquired antimicrobial resistance in Gram-negative bacteria

Arzanlou, M., Chai, W. C., & Venter, H. (2017) · Essays in Biochemistry · doi:10.1042/ebc20160063 · Cited by 222

Bacterial persisters: formation, eradication, and experimental systems

Hélaine, S., & Kugelberg, E. (2014) · Trends in Microbiology · doi:10.1016/j.tim.2014.03.008 · Cited by 221

Spirochete antigens persist near cartilage after murine Lyme borreliosis therapy

Bockenstedt, L. K., Gonzalez, D. G., Haberman, A. M., & Belperron, A. A. (2012) · Journal of Clinical Investigation · doi:10.1172/jci58813 · Cited by 219

Importance of Biofilms in Urinary Tract Infections: New Therapeutic Approaches

Soto, S. M. (2014) · Advances in Biology · doi:10.1155/2014/543974 · Cited by 219

Effective Removal of Staphylococcal Biofilms by the Endolysin LysH5

Gutiérrez, D., Ruas‐Madiedo, P., Martı́nez, B., Rodrı́guez, A., & García, P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107307 · Cited by 218

Emergence of antibiotic resistance from multinucleated bacterial filaments

Bos, J., Zhang, Q., Vyawahare, S., Rogers, E. J., Rosenberg, S. M., & Austin, R. H. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1420702111 · Cited by 223

Phenazine redox cycling enhances anaerobic survival in P seudomonas aeruginosa by facilitating generation of ATP and a proton‐motive force

Glasser, N. R., Kern, S. E., & Newman, D. K. (2014) · Molecular Microbiology · doi:10.1111/mmi.12566 · Cited by 215

Fighting biofilms with lantibiotics and other groups of bacteriocins

Mathur, H., Field, D., Rea, M. C., Cotter, P. D., Hill, C., & Ross, R. P. (2018) · npj Biofilms and Microbiomes · doi:10.1038/s41522-018-0053-6 · Cited by 223

Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

Martinez, M. N., Papich, M. G., & Drusano, G. L. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.05360-11 · Cited by 212

Diagnosis for Latent Tuberculosis Infection: New Alternatives

Carranza, C., Pedraza‐Sánchez, S., de Oyarzabal-Mendez, E., & Torres, M. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.02006 · Cited by 223

Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells

Goormaghtigh, F., Fraikin, N., Putrinš, M., Hallaert, T., Hauryliuk, V., García-Pino, A., Sjödin, A., Kasvandik, S., Udekwu, K. I., Tenson, T., et al. (2018) · mBio · doi:10.1128/mbio.00640-18 · Cited by 210

Toxin-Antitoxin systems: their role in persistence, biofilm formation, and pathogenicity

Wen, Y., Behiels, E., & Devreese, B. V. (2014) · Pathogens and Disease · doi:10.1111/2049-632x.12145 · Cited by 209

Review on bacterial biofilm: An universal cause of contamination

Satpathy, S., Sen, S. K., Pattnaik, S., & Raut, S. (2016) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2016.05.002 · Cited by 209

Ecology and Evolution as Targets: the Need for Novel Eco-Evo Drugs and Strategies To Fight Antibiotic Resistance

Baquero, F., Coque, T. M., & de la Cruz, F. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00013-11 · Cited by 212

Epigenetics in natural animal populations

Hu, J., & Barrett, R. D. H. (2017) · Journal of Evolutionary Biology · doi:10.1111/jeb.13130 · Cited by 214

A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus

Kim, W., Zou, G., Hari, T. P. A., Wilt, I. K., Zhu, W., Galle, N., Faizi, H. A., Hendricks, G. L., Tori, K., Pan, W., et al. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1904700116 · Cited by 208

Anaerobic Bacteria Grow within Candida albicans Biofilms and Induce Biofilm Formation in Suspension Cultures

Fox, E. P., Cowley, E. S., Nobile, C. J., Hartooni, N., Newman, D. K., & Johnson, A. D. (2014) · Current Biology · doi:10.1016/j.cub.2014.08.057 · Cited by 207

Slow growth determines nonheritable antibiotic resistance in Salmonella enterica

Pontes, M. H., & Groisman, E. A. (2019) · Science Signaling · doi:10.1126/scisignal.aax3938 · Cited by 216

Toxin-antitoxin systems are ubiquitous and versatile modulators of prokaryotic cell fate

Schuster, C. F., & Bertram, R. (2013) · FEMS Microbiology Letters · doi:10.1111/1574-6968.12074 · Cited by 206

Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection

de Melo, W. C., Avci, P., Moritz, M. N. D. O., Gupta, A. K., Vecchio, D., Sadasivam, M., Chandran, R., Huang, Y., Yin, R., Perussi, L. R., et al. (2013) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.2013.811861 · Cited by 211

Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic

Barrett, T. C., Mok, W. W. K., Murawski, A. M., & Brynildsen, M. P. (2019) · Nature Communications · doi:10.1038/s41467-019-09058-4 · Cited by 206

Phenotypic Resistance to Antibiotics

Corona, F., & Martinez, J. (2013) · Antibiotics · doi:10.3390/antibiotics2020237 · Cited by 205

Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance

Hicks, N. D., Yang, J., Zhang, X., Zhao, B. T., Grad, Y. H., Liu, L., Ou, X., Chang, Z., Xia, H., Zhou, Y., et al. (2018) · Nature Microbiology · doi:10.1038/s41564-018-0218-3 · Cited by 207

A method for high throughput determination of viable bacteria cell counts in 96-well plates

Hazan, R., Que, Y., Maura, D., & Rahme, L. G. (2012) · BMC Microbiology · doi:10.1186/1471-2180-12-259 · Cited by 202

Epistasis between antibiotic tolerance, persistence, and resistance mutations

Levin-Reisman, I., Brauner, A., Ronin, I., & Balaban, N. Q. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1906169116 · Cited by 216

Teixobactin kills bacteria by a two-pronged attack on the cell envelope

Shukla, R., Lavore, F., Maity, S., Derks, M. G. N., Jones, C. R., Vermeulen, B. J. A., Melcrová, A., Morris, M. A., Becker, L. M., Wang, X., et al. (2022) · Nature · doi:10.1038/s41586-022-05019-y · Cited by 201

Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa

Briers, Y., Walmagh, M., Grymonprez, B., Biebl, M., Pirnay, J., Defraine, V., Michiels, J. J., Cenens, W., Aertsen, A., Miller, S., et al. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02668-14 · Cited by 201

Mucosal biofilms of Candida albicans

Ganguly, S., & Mitchell, A. P. (2011) · Current Opinion in Microbiology · doi:10.1016/j.mib.2011.06.001 · Cited by 200

Persistence of Borrelia burgdorferi in Rhesus Macaques following Antibiotic Treatment of Disseminated Infection

Embers, M. E., Barthold, S. W., Borda, J. T., Bowers, L. C., Doyle, L. A., Hodzic, E., Jacobs, M. B., Hasenkampf, N. R., Martin, D. S., Narasimhan, S., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029914 · Cited by 197

The Toxin-Antitoxin System DarTG Catalyzes Reversible ADP-Ribosylation of DNA

Jankevicius, G., Ariza, A., Ahel, M., & Ahel, I. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.11.014 · Cited by 204

Cold Plasmas for Biofilm Control: Opportunities and Challenges

Gilmore, B., Flynn, P. B., O’Brien, S., Hickok, N. J., Freeman, T. A., & Bourke, P. (2018) · Trends in biotechnology · doi:10.1016/j.tibtech.2018.03.007 · Cited by 195

Burkholderia cepacia Complex Bacteria: a Feared Contamination Risk in Water-Based Pharmaceutical Products

Tavares, M., Kozak, M., Balola, A., & Sá‐Correia, I. (2020) · Clinical Microbiology Reviews · doi:10.1128/cmr.00139-19 · Cited by 207

Bacteria That Make a Meal of Sulfonamide Antibiotics: Blind Spots and Emerging Opportunities

Deng, Y., Li, B. J., & Zhang, T. (2018) · Environmental Science & Technology · doi:10.1021/acs.est.7b06026 · Cited by 196

The Interaction of Bacteria with Engineered Nanostructured Polymeric Materials: A Review

Armentano, I., Arciola, C. R., Fortunati, E., Ferrari, D., Mattioli, S., Amoroso, C. F., Rizzo, J., Kenny, J. M., Imbriani, M., & Visai, L. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/410423 · Cited by 189

Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance

Javid, B., Sorrentino, F., Toosky, M., Zheng, W., Pinkham, J. T., Jain, N. K., Pan, M., Deighan, P., & Rubin, E. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1317580111 · Cited by 194

Candida Survival Strategies

Polke, M., Hube, B., & Jacobsen, I. D. (2015) · Advances in applied microbiology · doi:10.1016/bs.aambs.2014.12.002 · Cited by 205

Pharmacodynamics, Population Dynamics, and the Evolution of Persistence in Staphylococcus aureus

Johnson, P. J., & Levin, B. R. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003123 · Cited by 187

Age of Inoculum Strongly Influences Persister Frequency and Can Mask Effects of Mutations Implicated in Altered Persistence

Luidalepp, H., Jõers, A., Kaldalu, N., & Tenson, T. (2011) · Journal of Bacteriology · doi:10.1128/jb.00085-11 · Cited by 187

Bacterial persistence is an active σS stress response to metabolic flux limitation

Radzikowski, J. L., Vedelaar, S. R., Siegel, D. J., Ortega, A. D., Schmidt, A., & Heinemann, M. (2016) · Molecular Systems Biology · doi:10.15252/msb.20166998 · Cited by 186

General Mechanisms Leading to Persister Formation and Awakening

Wilmaerts, D., Windels, E. M., Verstraeten, N., & Michiels, J. J. (2019) · Trends in Genetics · doi:10.1016/j.tig.2019.03.007 · Cited by 186

Heterogeneous bacterial persisters and engineering approaches to eliminate them

Allison, K. R., Brynildsen, M. P., & Collins, J. J. (2011) · Current Opinion in Microbiology · doi:10.1016/j.mib.2011.09.002 · Cited by 185

Anti-biofilm agents: recent breakthrough against multi-drug resistantStaphylococcus aureus

Chung, P. Y., & Toh, Y. S. (2014) · Pathogens and Disease · doi:10.1111/2049-632x.12141 · Cited by 186

Challenges of antibiotic resistance biofilms and potential combating strategies: a review

Khan, J., Tarar, S. M., Gul, I., Nawaz, U., & Arshad, M. (2021) · 3 Biotech · doi:10.1007/s13205-021-02707-w · Cited by 183

Mannitol Enhances Antibiotic Sensitivity of Persister Bacteria in Pseudomonas aeruginosa Biofilms

Barraud, N., Buson, A., Jarolimek, W., & Rice, S. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0084220 · Cited by 182

Mesoporous Silica‐Based Materials with Bactericidal Properties

Bernardos, A., Piacenza, E., Sancenón, F., Hamidi, M., Maleki, A., Turner, R. J., & Martínez‐Máñez, R. (2019) · Small · doi:10.1002/smll.201900669 · Cited by 181

Pseudomonas aeruginosa biofilms and their partners in crime

Cendra, M. D. M., & Torrents, E. (2021) · Biotechnology Advances · doi:10.1016/j.biotechadv.2021.107734 · Cited by 190

Drug-tolerant persister cells in cancer: the cutting edges and future directions

Pu, Y., Li, L., Peng, H., Liu, L., Heymann, D., Robert, C., Vallette, F. M., & Shen, S. (2023) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-023-00815-5 · Cited by 189

Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens

Cywes‐Bentley, C., Skurnik, D., Zaidi, T., Roux, D., DeOliveira, R. B., Garrett, W. S., Lü, X., O'Malley, J. M., Kinzel, K., Zaidi, T. H., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1303573110 · Cited by 178

Candida auris: Disinfectants and Implications for Infection Control

Ku, T. S. N., Walraven, C. J., & Lee, S. A. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.00726 · Cited by 177

Microbial biofilm formation: a need to act

Römling, U., Kjelleberg, S. J., Normark, S. J., Nyman, L., Uhlin, B. E., & Åkerlund, B. (2014) · Journal of Internal Medicine · doi:10.1111/joim.12242 · Cited by 185

Microbial bet-hedging: the power of being different

Grimbergen, A. J., Siebring, J., Solopova, A., & Kuipers, O. P. (2015) · Current Opinion in Microbiology · doi:10.1016/j.mib.2015.04.008 · Cited by 177

Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells

Sharma, B., Brown, A. V., Matluck, N. E., Hu, L. T., & Lewis, K. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00864-15 · Cited by 175

Biologically Active and Antimicrobial Peptides from Plants

Salas, C. E., Badillo-Corona, J. A., Ramírez-Sotelo, M.-G., & Oliver-Salvador, C. (2015) · BioMed Research International · doi:10.1155/2015/102129 · Cited by 180

Aloe-emodin inhibits Staphylococcus aureus biofilms and extracellular protein production at the initial adhesion stage of biofilm development

Xiang, H., Cao, F., Di, M., Zheng, Y., Dong, X., Zhong, X., Mu, D., Li, B., Zhong, L., Cao, J., et al. (2017) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-017-8403-5 · Cited by 175

Mechanisms of Bacterial Tolerance and Persistence in the Gastrointestinal and Respiratory Environments

Trastoy, R., Manso, T., Fernández-García, L., Blasco, L., Ambroa, A., del Molino, M. L. P., Bou, G., García‐Contreras, R., Wood, T. K., & Tomás, M. (2018) · Clinical Microbiology Reviews · doi:10.1128/cmr.00023-18 · Cited by 185

Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response

Pribis, J. P., Garcı́a-Villada, L., Zhai, Y., Lewin‐Epstein, O., Wang, A. Z., Liu, J., Xia, J., Mei, Q., Fitzgerald, D. M., Bos, J., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.02.037 · Cited by 177

The role of bacterial metabolism in antimicrobial resistance

Ahmad, M., Aduru, S. V., Smith, R. P., Zhao, Z., & Lopatkin, A. J. (2025) · Nature Reviews Microbiology · doi:10.1038/s41579-025-01155-0 · Cited by 186

Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

Saunders, E. C., Ng, W. W., Kloehn, J., Chambers, J. M., Ng, M., & McConville, M. J. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1003888 · Cited by 171

Toxin–antitoxin systems and their role in disseminating and maintaining antimicrobial resistance

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Thinking Outside the Box—Novel Antibacterials To Tackle the Resistance Crisis

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