Persister Cells

Bacterial Biofilms: A Common Cause of Persistent Infections

Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167

Antimicrobial peptides of multicellular organisms

Zasloff, M. (2002) · Nature · doi:10.1038/415389a · Cited by 8,457

Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection

Baba, T., Ara, T., Hasegawa, M., Takai, Y., Okumura, Y., Baba, M., Datsenko, K. A., Tomita, M., Wanner, B. L., & Mori, H. (2006) · Molecular Systems Biology · doi:10.1038/msb4100050 · Cited by 7,858

Antibiotic resistance of bacteria in biofilms

Stewart, P. S., & Costerton, J. W. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05321-1 · Cited by 4,596

Antibacterial resistance worldwide: causes, challenges and responses

Levy, S. B., & Marshall, B. M. (2004) · Nature Medicine · doi:10.1038/nm1145 · Cited by 4,152

A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics

Kohanski, M. A., Dwyer, D. J., Hayete, B., Lawrence, C. A., & Collins, J. J. (2007) · Cell · doi:10.1016/j.cell.2007.06.049 · Cited by 2,982

Bacterial Persistence as a Phenotypic Switch

Balaban, N. Q., Merrin, J., Chait, R., Kowalik, L., & Leibler, S. (2004) · Science · doi:10.1126/science.1099390 · Cited by 2,952

Stochasticity in gene expression: from theories to phenotypes

Kærn, M., Elston, T. C., Blake, W. J., & Collins, J. J. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1615 · Cited by 2,318

Chemotaxis in Escherichia coli analysed by Three-dimensional Tracking

Berg, H. C., & Brown, D. A. (1972) · Nature · doi:10.1038/239500a0 · Cited by 2,239

Persister cells, dormancy and infectious disease

Lewis, K. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1557 · Cited by 2,052

Fresh Approaches to Anti-Infective Therapies

Nathan, C. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003081 · Cited by 167

Potential Antibacterial Activity of Carvacrol-Loaded Poly(DL-lactide-co-glycolide) (PLGA) Nanoparticles against Microbial Biofilm

Iannitelli, A., Grande, R., Stefano, A. D., Giulio, M. D., Sozio, P., Bessa, L. J., Laserra, S., Paolini, C., Protasi, F., & Cellini, L. (2011) · International Journal of Molecular Sciences · doi:10.3390/ijms12085039 · Cited by 161

Culture History and Population Heterogeneity as Determinants of Bacterial Adaptation: the Adaptomics of a Single Environmental Transition

Ryall, B., Eydallin, G., & Ferenci, T. (2012) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.05028-11 · Cited by 160

Antimicrobial, anti-adhesive and anti-biofilm potential of biosurfactants isolated from Pediococcus acidilactici and Lactobacillus plantarum against Staphylococcus aureus CMCC26003

Yan, X., Gu, S., Cui, X., Shi, Y., Wen, S., Chen, H., & Ge, J. (2018) · Microbial Pathogenesis · doi:10.1016/j.micpath.2018.11.039 · Cited by 160

Mechanisms of Antibiotic Failure During Staphylococcus aureus Osteomyelitis

Gimza, B. D., & Cassat, J. E. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.638085 · Cited by 173

Green synthesis of silver nanoparticle using Oscillatoria sp. extract, its antibacterial, antibiofilm potential and cytotoxicity activity

Adebayo‐Tayo, B. C., Salaam, A. M., & Ajibade, A. (2019) · Heliyon · doi:10.1016/j.heliyon.2019.e02502 · Cited by 157

Immune cell interactions in tuberculosis

Flynn, J. L., & Chan, J. (2022) · Cell · doi:10.1016/j.cell.2022.10.025 · Cited by 161

Pathogens protection against the action of disinfectants in multispecies biofilms

Sanchez-Vizuete, P., Orgaz, B., Aymerich, S., Coq, D. L., & Briandet, R. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00705 · Cited by 168

Global Distribution of Polaromonas Phylotypes - Evidence for a Highly Successful Dispersal Capacity

Darcy, J. L., Lynch, R. C., King, A. J., Robeson, M. S., & Schmidt, S. K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0023742 · Cited by 156

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

Defraine, V., Schuermans, J., Grymonprez, B., Govers, S. K., Aertsen, A., Fauvart, M., Michiels, J. J., Lavigne, R., & Briers, Y. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00285-16 · Cited by 161

Developing a New Generation of Antimicrobial and Bioactive Dental Resins

Cheng, L., Zhang, K., Zhang, N., Melo, M. A. S., Weir, M. D., Zhou, X., Bai, Y., Reynolds, M. A., & Xu, H. H. K. (2017) · Journal of Dental Research · doi:10.1177/0022034517709739 · Cited by 156

Two heme-dependent terminal oxidases power Staphylococcus aureus organ-specific colonization of the vertebrate host

Hammer, N. D., Reniere, M. L., Cassat, J. E., Zhang, Y., Hirsch, A. O., Indriati Hood, M., & Skaar, E. P. (2013) · mBio · doi:10.1128/mbio.00241-13 · Cited by 155

Genetic Basis of Persister Tolerance to Aminoglycosides in Escherichia coli

Shan, Y., Lazinski, D. W., Rowe, S. E., Camilli, A., & Lewis, K. (2015) · mBio · doi:10.1128/mbio.00078-15 · Cited by 155

Persistence in Phytopathogenic Bacteria: Do We Know Enough?

Martins, P. M. M., Merfa, M. V., Takita, M. A., & de Souza, A. A. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01099 · Cited by 155

Inherent Guanidine Nanogels with Durable Antibacterial and Bacterially Antiadhesive Properties

Han, H., Zhu, J., Wu, D., Li, F., Wang, X., Yu, J., & Qin, X. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201806594 · Cited by 155

Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation

Tomlinson, K. L., Lung, T. W. F., Dach, F., Annavajhala, M. K., Gabryszewski, S. J., Groves, R. A., Drikic, M., Francoeur, N. J., Sridhar, S. H., Smith, M. L., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21718-y · Cited by 165

Recent Progress in Lyme Disease and Remaining Challenges

Bobe, J. R., Jutras, B. L., Horn, E. J., Embers, M. E., Bailey, A., Moritz, R. L., Zhang, Y., Soloski, M. J., Ostfeld, R. S., Marconi, R. T., et al. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2021.666554 · Cited by 169

A review of microbial biofilms of produce: Future challenge to food safety

Jahid, I. K., & Ha, S. (2012) · Food Science and Biotechnology · doi:10.1007/s10068-012-0041-1 · Cited by 154

Inhibition of Quorum Sensing (QS) in Yersinia enterocolitica by an Orange Extract Rich in Glycosylated Flavanones

Truchado, P., Giménez‐Bastida, J. A., Larrosa, M., Castro-Ibáñez, I., Espı́n, J. C., Tomás-Barberán, F. A., García‐Conesa, M., & Allende, A. (2012) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf301365a · Cited by 153

Emerging Concern for Silver Nanoparticle Resistance in Acinetobacter baumannii and Other Bacteria

McNeilly, O., Mann, R., Hamidian, M., & Gunawan, C. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.652863 · Cited by 153

Building-in biosafety for synthetic biology

Wright, O., Stan, G.-B. V., & Ellis, T. (2013) · Microbiology · doi:10.1099/mic.0.066308-0 · Cited by 156

Inhibition of stationary phase respiration impairs persister formation in E. coli

Orman, M. A., & Brynildsen, M. P. (2015) · Nature Communications · doi:10.1038/ncomms8983 · Cited by 155

Are viruses alive? The replicator paradigm sheds decisive light on an old but misguided question

Koonin, E. V., & Starokadomskyy, P. (2016) · Studies in History and Philosophy of Science Part C Studies in History and Philosophy of Biological and Biomedical Sciences · doi:10.1016/j.shpsc.2016.02.016 · Cited by 149

New-found fundamentals of bacterial persistence

Kint, C. I., Verstraeten, N., Fauvart, M., & Michiels, J. J. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.08.009 · Cited by 154

The influence of biofilm formation and multidrug resistance on environmental survival of clinical and environmental isolates of Acinetobacter baumannii

Greene, C., Vadlamudi, G., Newton, D. W., Foxman, B., & Xi, C. (2016) · American Journal of Infection Control · doi:10.1016/j.ajic.2015.12.012 · Cited by 147

Recent advances in understanding the control of disinfectant-resistant biofilms by hurdle technology in the food industry

Yuan, L., Sadiq, F. A., Wang, N., Yang, Z., & He, G. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1809345 · Cited by 147

Investigating the physiology of viable but non-culturable bacteria by microfluidics and time-lapse microscopy

Bamford, R. A., Smith, A., Metz, J., Glover, G., Titball, R. W., & Pagliara, S. (2017) · BMC Biology · doi:10.1186/s12915-017-0465-4 · Cited by 144

The Fatty Acid Signaling Molecule cis -2-Decenoic Acid Increases Metabolic Activity and Reverts Persister Cells to an Antimicrobial-Susceptible State

Marques, C. N. H., Morozov, A., Planzos, P., & Zelaya, H. M. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.01576-14 · Cited by 143

Viable but Nonculturable and Persister Cells Coexist Stochastically and Are Induced by Human Serum

Ayrapetyan, M., Williams, T. C., Baxter, R., & Oliver, J. D. (2015) · Infection and Immunity · doi:10.1128/iai.00404-15 · Cited by 143

Biofilm Management in Wound Care

Sen, C. K., Roy, S., Mathew‐Steiner, S. S., & Gordillo, G. M. (2021) · Plastic & Reconstructive Surgery · doi:10.1097/prs.0000000000008142 · Cited by 149

Keeping the Wolves at Bay: Antitoxins of Prokaryotic Type II Toxin-Antitoxin Systems

Chan, W. T., Espinosa, M., & Yeo, C. C. (2016) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2016.00009 · Cited by 147

In vitro methods for the evaluation of antimicrobial surface designs

Sjollema, J., Zaat, S. A. J., Fontaine, V., Ramstedt, M., Luginbuehl, R., Thevissen, K., Li, J., van der Mei, H. C., & Busscher, H. J. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.02.001 · Cited by 142

Persister Heterogeneity Arising from a Single Metabolic Stress

Amato, S. M., & Brynildsen, M. P. (2015) · Current Biology · doi:10.1016/j.cub.2015.06.034 · Cited by 141

In vitro and ex vivo systems at the forefront of infection modeling and drug discovery

Shi, D., Mi, G., Wang, M., & Webster, T. J. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.10.030 · Cited by 145

A multiplexed microfluidic platform for rapid antibiotic susceptibility testing

Mohan, R., Mukherjee, A., Sevgen, S. E., Sanpitakseree, C., Lee, J., Schroeder, C. M., & Kenis, P. J. A. (2013) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2013.04.046 · Cited by 139

Insights into Feast-Famine polyhydroxyalkanoate (PHA)-producer selection: Microbial community succession, relationships with system function and underlying driving forces

Huang, L., Chen, Z., Wen, Q., Zhao, L., Lee, D., Yang, L., & Wang, Y. (2017) · Water Research · doi:10.1016/j.watres.2017.12.033 · Cited by 139

Generation of Persister Cells of Pseudomonas aeruginosa and Staphylococcus aureus by Chemical Treatment and Evaluation of Their Susceptibility to Membrane-Targeting Agents

Grassi, L. C., Luca, M. D., Maisetta, G., Rinaldi, A. C., Esin, S., Trampuž, A., & Batoni, G. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01917 · Cited by 138

Engineering biofilm formation and dispersal

Wood, T. K., Hong, S. H., & Ma, Q. (2010) · Trends in biotechnology · doi:10.1016/j.tibtech.2010.11.001 · Cited by 140

Candida albicans biofilms: antifungal resistance, immune evasion, and emerging therapeutic strategies

Fan, F., Liu, Y., Liu, Y., Lv, R., Sun, W., Ding, W., Cai, Y., Li, W., Liu, X., & Qu, W. (2022) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2022.106673 · Cited by 140

Fungal persister cells: The basis for recalcitrant infections?

Wuyts, J., Van Dijck, P., & Holtappels, M. (2018) · PLOS Pathogens · doi:10.1371/journal.ppat.1007301 · Cited by 136

Cecum Lymph Node Dendritic Cells Harbor Slow-Growing Bacteria Phenotypically Tolerant to Antibiotic Treatment

Kaiser, P., Regoes, R. R., Dolowschiak, T., Wotzka, S. Y., Lengefeld, J., Slack, E. M. C., Grant, A. J., Ackermann, M., & Hardt, W. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001793 · Cited by 136

Stochastic Variation in Expression of the Tricarboxylic Acid Cycle Produces Persister Cells

Zalis, E. A., Nuxoll, A. S., Manuse, S., Clair, G., Radlinski, L. C., Conlon, B. P., Adkins, J., & Lewis, K. (2019) · mBio · doi:10.1128/mbio.01930-19 · Cited by 139

Impact of pH on citric acid antimicrobial activity against Gram‐negative bacteria

Burel, C., Kala, A., & Purevdorj-Gage, L. (2020) · Letters in Applied Microbiology · doi:10.1111/lam.13420 · Cited by 136

Biofilm-Grown Burkholderia cepacia Complex Cells Survive Antibiotic Treatment by Avoiding Production of Reactive Oxygen Species

Van Acker, H., Sass, A., Bazzini, S., De Roy, K., Udine, C., Messiaen, T., Riccardi, G., Boon, N., Nelis, H. J., Mahenthiralingam, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058943 · Cited by 135

Controlling bacterial behavior with indole-containing natural products and derivatives

Melander, R. J., Minvielle, M. J., & Melander, C. (2014) · Tetrahedron · doi:10.1016/j.tet.2014.05.089 · Cited by 135

A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence

Kim, J.-H., O’Brien, K. M., Sharma, R. S., Boshoff, H. I., Rehren, G., Chakraborty, S., Wallach, J. B., Monteleone, M. M., Wilson, D. J., Aldrich, C. C., et al. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1315860110 · Cited by 134

Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR

Maura, D., Hazan, R., Kitao, T., Ballok, A. E., & Rahme, L. G. (2016) · Scientific Reports · doi:10.1038/srep34083 · Cited by 134

Developing next generation antimicrobials by intercepting AI-2 mediated quorum sensing

Roy, V., Adams, B. L., & Bentley, W. E. (2011) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2011.06.001 · Cited by 133

Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site

Schifano, J. M., Edifor, R., Sharp, J. D., Ouyang, M., Konkimalla, A., Husson, R. N., & Woychik, N. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222031110 · Cited by 140

Mechanisms and Impact of Biofilms and Targeting of Biofilms Using Bioactive Compounds—A Review

Samrot, A. V., Mohamed, A. A., Faradjeva, E., Jie, L. S., Sze, C. H., Arif, A., Sean, T. C., Michael, E. N., Mun, C. Y., Ng, X. Q., et al. (2021) · Medicina · doi:10.3390/medicina57080839 · Cited by 140

Life on the outside: role of biofilms in environmental persistence of Shiga-toxin producing Escherichia coli

Vogeleer, P., Tremblay, Y. D. N., Mafu, A. A., Jacques, M., & Harel, J. (2014) · Frontiers in Microbiology · doi:10.3389/fmicb.2014.00317 · Cited by 144

Stationary-Phase Persisters to Ofloxacin Sustain DNA Damage and Require Repair Systems Only during Recovery

Volzing, K., & Brynildsen, M. P. (2015) · mBio · doi:10.1128/mbio.00731-15 · Cited by 132

Targeting Phenotypically Tolerant Mycobacterium tuberculosis

Gold, B. S., & Nathan, C. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.tbtb2-0031-2016 · Cited by 134

Pharmacological Considerations for the Proper Clinical Use of Aminoglycosides

Pagkalis, S., Mantadakis, E., Mavros, M. N., Ammari, C., & Falagas, M. E. (2011) · Drugs · doi:10.2165/11597020-000000000-00000 · Cited by 131

VapC20 of Mycobacterium tuberculosis cleaves the Sarcin–Ricin loop of 23S rRNA

Winther, K. S., Brodersen, D. E., Brown, A. K., & Gerdes, K. (2013) · Nature Communications · doi:10.1038/ncomms3796 · Cited by 131

Programmable DNA switches and their applications

Harroun, S. G., Prévost-Tremblay, C., Lauzon, D., Desrosiers, A., Wang, X., Pedro, L., & Vallée‐Bélisle, A. (2018) · Nanoscale · doi:10.1039/c7nr07348h · Cited by 131

Pseudomonas aeruginosa biofilm infections: From molecular biofilm biology to new treatment possibilities

Tolker‐Nielsen, T. (2014) · Apmis · doi:10.1111/apm.12335 · Cited by 133

Efflux Pump Induction by Quaternary Ammonium Compounds and Fluoroquinolone Resistance in Bacteria

Buffet‐Bataillon, S., Tattevin, P., Maillard, J., Bonnaure‐Mallet, M., & Jolivet‐Gougeon, A. (2015) · Future Microbiology · doi:10.2217/fmb.15.131 · Cited by 127

Characterization of Metagenomes in Urban Aquatic Compartments Reveals High Prevalence of Clinically Relevant Antibiotic Resistance Genes in Wastewaters

Ng, C., Tay, M., Tan, B., Le, T., Haller, L., Chen, H., Koh, T. H., Barkham, T., Thompson, J. R., & Gin, K. Y. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02200 · Cited by 131

Continuum and discrete approach in modeling biofilm development and structure: a review

Mattei, M. R., Frunzo, L., D’Acunto, B., Péchaud, Y., Pirozzi, F., & Esposito, G. (2017) · Journal of Mathematical Biology · doi:10.1007/s00285-017-1165-y · Cited by 126

Molecular Mechanisms Involved in the Response to Desiccation Stress and Persistence in Acinetobacter baumannii

Gayoso, C., Mateos, J., Méndez, J. A., Fernández‐Puente, P., Rumbo, C., Tomás, M., de Ilárduya, Ó. M., & Bou, G. (2013) · Journal of Proteome Research · doi:10.1021/pr400603f · Cited by 125

Vancomycin resistant enterococci: From the hospital effluent to the urban wastewater treatment plant

Varela, A. R., Ferro, G., Vredenburg, J., Yanık, M., Vieira, L., Rizzo, L., Lameiras, C., & Manaia, C. M. (2013) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2013.02.015 · Cited by 124

A Single Promoter Inversion Switches Photorhabdus Between Pathogenic and Mutualistic States

Somvanshi, V. S., Sloup, R. E., Crawford, J. M., Martin, A. R., Heidt, A. J., Kim, K., Clardy, J., & Ciche, T. A. (2012) · Science · doi:10.1126/science.1216641 · Cited by 126

Emerging Mechanisms of Antimicrobial Resistance in Bacteria and Fungi: Advances in the Era of Genomics

Sekyere, J. O., & Asante, J. (2018) · Future Microbiology · doi:10.2217/fmb-2017-0172 · Cited by 123

Antibiotic Resistance: From Pig to Meat

Monger, X. C., Gilbert, A.-A., Saucier, L., & Vincent, A. T. (2021) · Antibiotics · doi:10.3390/antibiotics10101209 · Cited by 123

An Experimental Framework for Quantifying Bacterial Tolerance

Brauner, A., Shoresh, N., Fridman, O., & Balaban, N. Q. (2017) · Biophysical Journal · doi:10.1016/j.bpj.2017.05.014 · Cited by 122

New approaches to antimicrobial discovery

Lewis, K. (2016) · Biochemical Pharmacology · doi:10.1016/j.bcp.2016.11.002 · Cited by 126

Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis

Lee, J. J., Lee, S.-K., Song, N., Nathan, T. O., Swarts, B. M., Eum, S.-Y., Ehrt, S., Cho, S.-N., & Eoh, H. (2019) · Nature Communications · doi:10.1038/s41467-019-10975-7 · Cited by 122

Metabolic aspects of bacterial persisters

Prax, M., & Bertram, R. (2014) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2014.00148 · Cited by 122

Emerging Roles of Toxin-Antitoxin Modules in Bacterial Pathogenesis

Kędzierska, B., & Hayes, F. (2016) · Molecules · doi:10.3390/molecules21060790 · Cited by 121

Principles of seed banks and the emergence of complexity from dormancy

Lennon, J. T., den Hollander, F., Wilke-Berenguer, M., & Blath, J. (2021) · Nature Communications · doi:10.1038/s41467-021-24733-1 · Cited by 121

Pyrazinamide resistance in Mycobacterium tuberculosis: Review and update

Njire, M. M., Tan, Y., Mugweru, J., Wang, C., Guo, J. T., Yew, W.-W., Tan, S., & Zhang, T. (2015) · Advances in Medical Sciences · doi:10.1016/j.advms.2015.09.007 · Cited by 120

Artificial activation of toxin–antitoxin systems as an antibacterial strategy

Williams, J. J., & Hergenrother, P. J. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.02.005 · Cited by 120

Bacterial biofilms in the vagina

Hardy, L., Cerca, N., Jespers, V., Vaneechoutte, M., & Crucitti, T. (2017) · Research in Microbiology · doi:10.1016/j.resmic.2017.02.001 · Cited by 120

Superoxide dismutases are involved in Candida albicans biofilm persistence against miconazole

Bink, A., Vandenbosch, D., Coenye, T., Nelis, H., Cammue, B. P. A., & Thevissen, K. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00280-11 · Cited by 119

Molecular mechanisms of multiple toxin–antitoxin systems are coordinated to govern the persister phenotype

Fasani, R. A., & Savageau, M. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1301023110 · Cited by 119

“Persisters”: Survival at the Cellular Level

Dawson, C. C., Intapa, C., & Jabra‐Rizk, M. A. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002121 · Cited by 125

MazF-induced Growth Inhibition and Persister Generation in Escherichia coli

Tripathi, A., Dewan, P. C., Ahmed, S., & Varadarajan, R. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.510511 · Cited by 118

Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone

Steinchen, W., Schuhmacher, J. S., Altegoer, F., Fage, C. D., Srinivasan, V., Linne, U., Marahiel, M. A., & Bange, G. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1505271112 · Cited by 119

Adaptation to Adversity: the Intermingling of Stress Tolerance and Pathogenesis in Enterococci

Gaca, A. O., & Lemos, J. A. C. (2019) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00008-19 · Cited by 127

The Toxin-Antitoxin MazEF Drives Staphylococcus aureus Biofilm Formation, Antibiotic Tolerance, and Chronic Infection

Ma, D., Mandell, J. B., Donegan, N. P., Cheung, A. L., Ma, W., Rothenberger, S. D., Shanks, R. M. Q., Richardson, A. R., & Urish, K. L. (2019) · mBio · doi:10.1128/mbio.01658-19 · Cited by 122

Biological Functions of Type II Toxin-Antitoxin Systems in Bacteria

Kamruzzaman, M., Wu, A. Y., & Iredell, J. R. (2021) · Microorganisms · doi:10.3390/microorganisms9061276 · Cited by 118

Reaching unreachables: Obstacles and successes of microbial cultivation and their reasons

Kapinusová, G., Marin, M. A. L., & Uhlík, O. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1089630 · Cited by 120

Cellular noise and information transmission

Levchenko, A., & Nemenman, I. M. (2014) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2014.05.002 · Cited by 116

Bacteriophages for Chronic Wound Treatment: From Traditional to Novel Delivery Systems

Pinto, A. M., Cerqueira, M. Â., Bañobre‐López, M., Pastrana, L. M., & Sillankorva, S. (2020) · Viruses · doi:10.3390/v12020235 · Cited by 115

Tolerance and Persistence of Pseudomonas aeruginosa in Biofilms Exposed to Antibiotics: Molecular Mechanisms, Antibiotic Strategies and Therapeutic Perspectives

Soares, A., Alexandre, K., & Etienne, M. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.02057 · Cited by 126

Antidepressants can induce mutation and enhance persistence toward multiple antibiotics

Wang, Y., Yu, Z., Ding, P., Lu, J., Mao, L., Ngiam, L., Yuan, Z., Engelstädter, J., Schembri, M. A., & Guo, J. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2208344120 · Cited by 115

Stress-Induced Remodeling of the Bacterial Proteome

Guo, M. S., & Gross, C. A. (2014) · Current Biology · doi:10.1016/j.cub.2014.03.023 · Cited by 120

Combatting bacterial persister cells

Wood, T. K. (2015) · Biotechnology and Bioengineering · doi:10.1002/bit.25721 · Cited by 114

Ecological Succession and Viability of Human-Associated Microbiota on Restroom Surfaces

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