Cited by 346Regulation of Appetite and ObesityHypothalamic control of reproductive hormonesNeurotransmitter Receptor Influence on Behavior

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Neurobiology of Feeding and Energy Expenditure

Gao, Qian, Horvath, Tamas L.·2007·Annual Review of Neuroscience

DOI 10.1146/annurev.neuro.30.051606.094324

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Abstract

Significant advancements have been made in the past century regarding the neuronal control of feeding behavior and energy expenditure. The effects and mechanisms of action of various peripheral metabolic signals on the brain have become clearer. Molecular and genetic tools for visualizing and manipulating individual components of brain homeostatic systems in combination with neuroanatomical, electrophysiological, behavioral, and pharmacological techniques have begun to elucidate the molecular and neuronal mechanisms of complex feeding behavior and energy expenditure. This review highlights some of these advancements that have led to the current understanding of the brain's involvement in the acute and chronic regulation of energy homeostasis.

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Authors: Gao, Q., & Horvath, T. L.
Affiliations: Yale University (US)
Section of Comparative Medicine and Departments of 2Neurobiology and 3Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut 06520;,
ORCID: Gao, Qian
Venue: Annual Review of Neuroscience
Publisher: Annual Reviews
Published: 2007-07-01
Volume: 30
Issue: 1
Pages: 367-398
ISSN: 0147-006X (ISSN-L)
1545-4126
DOI: 10.1146/annurev.neuro.30.051606.094324
OpenAlex: W2124738442
Cited by: 346
References: 221
Citations by year: 2025: 6 · 2024: 8 · 2023: 4 · 2022: 15 · 2021: 14 · 2020: 20 · 2019: 11 · 2018: 20 · 2017: 15 · 2016: 34 · 2015: 21 · 2014: 22 · 2013: 33 · 2012: 22
FWCI: 2.87
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Neuroscience (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (R01AG022880, AG-022880)
National Institute of Diabetes and Digestive and Kidney Diseases (DK 060711, DK074386, R01DK074386, R01DK060711)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: feeding behavior, energy expenditure, energy homeostasis
MeSH terms: Animals, Appetite Regulation, Energy Metabolism, Feeding Behavior, Hormones, Humans, Hypothalamus, Motivation, Neural Pathways, Leptin, Melanocortins

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Neurobiology of Feeding and Energy Expenditure

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