The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
G PROTEIN βγ SUBUNITS
Abstract
▪ Abstract Guanine nucleotide binding (G) proteins relay extracellular signals encoded in light, small molecules, peptides, and proteins to activate or inhibit intracellular enzymes and ion channels. The larger G proteins, made up of G αβγ heterotrimers, dissociate into G α and G βγ subunits that separately activate intracellular effector molecules. Only recently has the G βγ subunit been recognized as a signal transduction molecule in its own right; G βγ is now known to directly regulate as many different protein targets as the G α subunit. Recent X-ray crystallography of G α, G βγ, and G αβγ subunits will guide the investigation of structure-function relationships.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Predicting coiled coils from protein sequences.
Lupas, A., Van Dyke, M., & Stock, J. (1991) · Science · doi:10.1126/science.252.5009.1162 · Cited by 3,953
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
Tang, W.-J., & Gilman, A. G. (1991) · Science · doi:10.1126/science.1962211 · Cited by 1,091
Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits
Federman, A. D., Conklin, B. R., Schrader, K. A., Reed, R. R., & Bourne, H. R. (1992) · Nature · doi:10.1038/356159a0 · Cited by 624
Cali, J. J., Zwaagstra, J. C., Mons, N., Cooper, D. M., & Krupinski, J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32700-x · Cited by 363
Rotation of photoreceptor clusters in the developing drosophila eye requires the nemo gene
Choi, K.-W., & Benzer, S. (1994) · Cell · doi:10.1016/0092-8674(94)90579-7 · Cited by 339
Molecular and functional diversity of mammalian G s ‐stimulated adenylyl cyclases
Iyengar, R. (1993) · The FASEB Journal · doi:10.1096/fasebj.7.9.8330684 · Cited by 299
Cloning and expression of a Ca(2+)-inhibitable adenylyl cyclase from NCB-20 cells.
Yoshimura, M., & Cooper, D. M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.15.6716 · Cited by 268
Cited by
Gutkind, J. S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.4.1839 · Cited by 812
Activation of Platelet Function Through G Protein–Coupled Receptors
Offermanns, S. (2006) · Circulation Research · doi:10.1161/01.res.0000251742.71301.16 · Cited by 725
Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion
Lang, J. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00043.x · Cited by 347
RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?
Fukuhara, S., Chikumi, H., & Gutkind, J. S. (2001) · Oncogene · doi:10.1038/sj.onc.1204182 · Cited by 219
Imaging of opioid receptors in the central nervous system
Henriksen, G., & Willoch, F. (2008) · Brain · doi:10.1093/brain/awm255 · Cited by 214
The impact of opioid-induced hyperalgesia for postoperative pain
Koppert, W., & Schmelz, M. (2007) · Best Practice & Research Clinical Anaesthesiology · doi:10.1016/j.bpa.2006.12.004 · Cited by 154
DeBock, F., Kurz, J., Azad, S. C., Parsons, C. G., Hapfelmeier, G., Zieglgänsberger, W., & Rammes, G. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02544.x · Cited by 81
Xu, Y., Cantwell, L., Molosh, A. I., Plant, L. D., Gazgalis, D., Fitz, S. D., Dustrude, E. T., Yang, Y., Kawano, T., Garai, S., et al. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.011527 · Cited by 32
GPCR and Voltage-Gated Calcium Channels (VGCC) Signaling Complexes
Altier, C. (2012) · Subcellular Biochemistry · doi:10.1007/978-94-007-4765-4_13 · Cited by 22
Metadata
- Authors
- Clapham, D. E., & Neer, E. J.
- Venue
- Annual Review of Pharmacology and Toxicology
- Publisher
- Annual Reviews
- Published
- 1997-04
- Volume
- 37
- Issue
- 1
- Pages
- 167-203
- ISSN
- 0362-1642 (ISSN-L)
- 1545-4304
- OpenAlex
- W2168808956
- Cited by
- 842
- References
- 7
- FWCI
- 4.22
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
