The DOI matches its Crossref record; 119 of the 119 references it cites were found in a registry or an index.
Addiction
Abstract
The development of addiction involves a transition from casual to compulsive patterns of drug use. This transition to addiction is accompanied by many drug-induced changes in the brain and associated changes in psychological functions. In this article we present a critical analysis of the major theoretical explanations of how drug-induced alterations in psychological function might cause a transition to addiction. These include: (a) the traditional hedonic view that drug pleasure and subsequent unpleasant withdrawal symptoms are the chief causes of addiction; (b) the view that addiction is due to aberrant learning, especially the development of strong stimulus-response habits; (c) our incentive-sensitization view, which suggests that sensitization of a neural system that attributes incentive salience causes compulsive motivation or “wanting” to take addictive drugs; and (d) the idea that dysfunction of frontal cortical systems, which normally regulate decision making and inhibitory control over behavior, leads to impaired judgment and impulsivity in addicts.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The mesolimbic DA system represents only one component of a very complex and integrated set of circuits, and although DA is clearly a crucial neurotransmitter in the reward-processing system, non-DA systems clearly also modulate reward responsibility [19,735].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [735]
In the citing paper
“neural sensitization leads to strong impulsive reactions (e.g., attentional biases and approach tendencies) to classically conditioned cues that signal alcohol or drugs”
From Addiction, adolescence, and the integration of control and motivation (2011) · cites this paper as Robinson and Berridge, 2003
In the citing paper
“Current neurobiological research has identified two broad types of neuro-adaptations that result from repeated alcohol and drug use.”
From Addiction, adolescence, and the integration of control and motivation (2011) · cites this paper as Robinson and Berridge, 2003
In the citing paper
“The distinction between reward anticipation vs. reward receipt in the imaging literature in humans is reminiscent of the anticipatory/”wanting” vs. consummatory/”liking” distinctions drawn by Robinson & Berridge (2003).”
From Rewards, aversions and affect in adolescence: emerging convergences across laboratory animal and human data (2011) · cites this paper as Robinson & Berridge, 2003
In the citing paper
“In these studies as well, there are clear indications that, at least when using tests of sign-tracking to index “wanting” (Robinson & Berridge, 2003), adolescents frequently exhibit less anticipatory responding than do adults.”
From Rewards, aversions and affect in adolescence: emerging convergences across laboratory animal and human data (2011) · cites this paper as Robinson & Berridge, 2003
In the citing paper
“chronic substance abuse increases reward value while decreasing inhibitory control (Jentsch and Taylor, 1999; Robinson and Berridge, 2003).”
From Impulsivity, frontal lobes and risk for addiction (2009) · cites this paper as Robinson and Berridge, 2003
In the citing paper
“when addiction involves associative learning of unhealthy habit patterns that become entrenched and semi-automatic through repetition (Robinson and Berridge, 2003).”
From Impulsivity, frontal lobes and risk for addiction (2009) · cites this paper as Robinson and Berridge, 2003
Citations
Cites
The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346
Self-citationPredictive reward signal of dopamine neurons
Schultz, W. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.1.1 · Cited by 4,564
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
Self-citationEmotion, Decision Making and the Orbitofrontal Cortex
Bechara, A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.295 · Cited by 3,589
Drug Addiction, Dysregulation of Reward, and Allostasis
Koob, G. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00195-0 · Cited by 2,953
Storage and Executive Processes in the Frontal Lobes
Smith, E. E., & Jonides, J. (1999) · Science · doi:10.1126/science.283.5408.1657 · Cited by 2,834
A psychomotor stimulant theory of addiction.
Wise, R. A., & Bozarth, M. A. (1987) · Psychological Review · doi:10.1037/0033-295x.94.4.469 · Cited by 2,747
Drug abuse: hedonic homeostatic dysregulation
Koob, G. F., & Moal, M. L. (1997) · Science · doi:10.1126/science.278.5335.52 · Cited by 2,535
Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens
Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-j0002.2001 · Cited by 2,244
Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex
Cardinal, R. N., Parkinson, J. A., Hall, J., & Everitt, B. J. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00007-6 · Cited by 2,129
Research works printed but not linked: 24
- Antelman SM, Chiodo LA. 1983. Amphetamine as a stressor. In Stimulants: Neurochemical, Behavioral and Clinical Perspectives , ed. I Creese, pp. 269–99. New York: Raven
- Berridge KC. 1999. Pleasure, pain, desire and dread: hidden core processes of emotion. In Well Being: The Foundations of Hedonic Psychology , ed. D Kahneman, E Diener, N Schwarz, pp. 527–59. New York: Sage Found.
- Berridge KC, 2002, Brain Cogn.
- Berridge KC, 2002, Cogn. Emot.
- Childress AR, 1988, Natl. Inst. Drug Abuse Res. Monogr., 84, 25
- 10.1037//0033-2909.126.6.890 · DOI · Paper page
- Edwards G, 1981, Bull. WHO, 59, 225
- Hurvich LM, 1981, Color Vision.
- Johnston LD, 2001, Monitoring the Future National Survey Results on Drug Use, 1975–2000, Vol. II. College Students and Adults Ages 19–40.
- Lamb RJ, 1991, J. Pharmacol. Exp. Ther., 259, 1165
- O'Brien CP, Childress AR, McLellan AT, Ehrman R. 1992. A learning model of addiction. In Addictive States , ed. CP O'Brien, JH Jaffe, pp. 157–77. New York: Raven
- O'Brien CP, 1988, NIDA Res. Monogr., 84, 44
- Pert A, 1990, NIDA Res. Monogr., 97, 208
- 10.1037//0033-295X.104.1.170 · DOI · Paper page
- Robinson TE. 1988. Stimulant drugs and stress: factors influencing individual differences in the susceptibility to sensitization. In Sensitization of the Nervous System , ed. PW Kalivas, C Barnes, pp. 145–73. Caldwell, NJ: Telford · DOI
- 10.1080/09652140050111681 · DOI · Paper page
- Shippenberg TS, 1995, J. Pharmacol. Exp. Ther., 273, 808
- Solomon RL. 1977. Addiction: an opponent-process theory of acquired motivation: the affective dynamics of addiction. In Psychopathology: Experimental Models , ed. JD Maser, pp. 66–103. San Francisco: Freeman
- Stewart J, 2000, J. Psychiatry Neurosci., 25, 125
- 10.1037//0033-295X.97.2.147 · DOI · Paper page
- Washton AM, 1993, NIDA Res. Monogr., 135, 15
- 10.1046/j.1360-0443.1996.9179212.x · DOI · Paper page
- Wise RA. 1989. The brain and reward. In The Neuropharmacological Basis of Reward , ed. JM Liebman, SJ Cooper, pp. 377–424. New York: Oxford Univ. Press
- 10.1037//0033-295X.94.4.469 · DOI · Paper page
Cited by
Sorted by citations
Items 1,001–1,003 of 1,003
Effects of CNQX and MPEP on sensitization to the rewarding effects of morphine
Manzanedo, C., Aguilar, M. A., Miñarro, J., & Rodríguez‐Arias, M. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.11.037 · Cited by 12
Ferreira, G. K., Carvalho‐Silva, M., Gomes, L. M., Scaini, G., Teixeira, L. J., Mota, I. T., Schuck, P. F., Ferreira, G. C., & STRECK, E. L. (2014) · Metabolic Brain Disease · doi:10.1007/s11011-014-9615-3 · Cited by 12
Spence, A. L., Guerin, G. F., & Goeders, N. E. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.10.041 · Cited by 12
Metadata
- Authors
- Robinson, T. E., & Berridge, K. C.
- Affiliations
- University of Michigan (US)
- Venue
- Annual Review of Psychology
- Publisher
- Annual Reviews
- Published
- 2003-02
- Volume
- 54
- Issue
- 1
- Pages
- 25-53
- ISSN
- 0066-4308 (ISSN-L)
- 1545-2085
- OpenAlex
- W4213265599
- Cited by
- 1,509
- References
- 118
- Citations by year
- 2026: 15 · 2025: 29 · 2024: 35 · 2023: 33 · 2022: 26 · 2021: 36 · 2020: 75 · 2019: 49 · 2018: 58 · 2017: 58 · 2016: 71 · 2015: 59 · 2014: 89 · 2013: 118 · 2012: 81
- FWCI
- 3.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Psychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Foundation
- National Institute on Drug Abuse
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- addiction, compulsive drug use, withdrawal symptoms, incentive-sensitization theory, incentive salience, stimulus-response learning, impulsivity, decision-making, inhibitory control
- MeSH terms
- Animals, Brain, Conditioning, Psychological, Decision Making, Humans, Motivation, Neuronal Plasticity, Pleasure-Pain Principle, Illicit Drugs, Substance Withdrawal Syndrome, Substance-Related Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
