Cited by 194Metabolism, Diabetes, and CancerMuscle metabolism and nutritionCardiovascular and exercise physiology

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Enhanced muscle glucose metabolism after exercise: modulation by local factors

Richter, E. A., Garetto, L. P., Goodman, M. N., Ruderman, N. B.·1984·American Journal of Physiology-Endocrinology and Metabolism

DOI 10.1152/ajpendo.1984.246.6.e476

Open this paper in CoChat — free account

Abstract

Studies in the rat suggest that after voluntary exercise there are two phases of glycogen repletion in skeletal muscle (preceding study). In phase I glucose utilization and glycogen synthesis are enhanced both in the presence and absence of insulin, whereas in phase II only the increase in the presence of insulin is found. To determine whether these alterations and in particular those mediated by insulin are due to local or systemic factors, one hindlimb of an anesthetized rat was electrically stimulated, and both hindlimbs were perfused immediately thereafter. Glucose and glycogen metabolism in the stimulated leg closely mimicked that observed previously after voluntary exercise on a treadmill. With no insulin added to the perfusate, glucose incorporation into glycogen was markedly enhanced in muscles that were glycogen depleted as were the uptake of 2-deoxyglucose and 3-O-methylglucose. Likewise, the stimulation of these processes by insulin was enhanced and continued to be so 2 h later when the muscles of the stimulated leg had substantially repleted their glycogen stores. The results suggest that the increases in insulin-mediated glucose utilization and glycogen synthesis in muscle after exercise are modulated by local contraction-induced factors.

Integrity signals

Registry

Crossref · 10.1152/ajpendo.1984.246.6.e476

Cites

17 of 17 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A Flexible System of Enzymatic Analysis
Lowry, O. H., & Passonneau, J. V. (1972) · Elsevier eBooks · doi:10.1016/b978-0-12-457950-7.x5001-3 · Cited by 4,050
A rapid filter paper assay for UDPglucose-glycogen glucosyltransferase, including an improved biosynthesis of UDP-14C-glucose
Thomas, J. A., Schlender, K. K., & Larner, J. (1968) · Analytical Biochemistry · doi:10.1016/0003-2697(68)90127-9 · Cited by 1,198
HINDLIMB MUSCLE FIBER POPULATIONS OF FIVE MAMMALS
Ariano, M. A., Edgerton, V. R., & Armstrong, R. B. (1973) · Journal of Histochemistry & Cytochemistry · doi:10.1177/21.1.51 · Cited by 1,118
Insulin resistance, insulin insensitivity, and insulin unresponsiveness: A necessary distinction
Kahn, C. R. (1978) · Metabolism · doi:10.1016/s0026-0495(78)80007-9 · Cited by 793
Muscle Glucose Metabolism following Exercise in the Rat
Richter, E. A., Garetto, L. P., Goodman, M. N., & Ruderman, N. B. (1982) · Journal of Clinical Investigation · doi:10.1172/jci110517 · Cited by 510
Self-citation
ENZYMATIC CYCLING
Lowry, O. H., & Passonneau, J. V. (1972) · Elsevier eBooks · doi:10.1016/b978-0-12-457950-7.50011-5 · Cited by 457
Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism
Ruderman, N. B., Houghton, C. R. S., & Hems, R. (1971) · Biochemical Journal · doi:10.1042/bj1240639 · Cited by 446
Self-citation
Studies of Tissue Permeability
Holloszy, J. O., & NARAHARA, H. T. (1965) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)97170-x · Cited by 224
Muscle Metabolites during Submaximal and Maximal Exercise in Man
Karlsson, J., Diamant, B., & Saltin, B. (1970) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365517009046250 · Cited by 172
Effect of acetoacetate on glucose metabolism in the soleus and extensor digitorum longus muscles of the rat
Maizels, E. T., Ruderman, N. B., Goodman, M. N., & Lau, D. (1977) · Biochemical Journal · doi:10.1042/bj1620557 · Cited by 169
Self-citation

Show all 17 references

Research works printed but not linked: 3

GARETTO L. P., 1982, Physiologist, 25, 252
SHIKAMA H., D., Am. J. Physiol., 242
TAN M., 1983, Excerpta Med. Int. Congr. Ser., 577, 182

Sorted by citations

Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man
Lillioja, S., Young, A. A., Culter, C. L., Ivy, J. L., Abbott, W. G., Zawadzki, J. K., Yki-Järvinen, H., Christin, L., Secomb, T. W., & Bogardus, C. (1987) · Journal of Clinical Investigation · doi:10.1172/jci113088 · Cited by 782
AMPK in skeletal muscle function and metabolism
Kjøbsted, R., Hingst, J. R., Fentz, J., Foretz, M., Sanz, M.-N., Pehmøller, C. K., Shum, M., Marette, A., Mounier, R., Treebak, J. T., et al. (2017) · The FASEB Journal · doi:10.1096/fj.201700442r · Cited by 517
Exercise-induced increase in muscle insulin sensitivity
Holloszy, J. O. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00123.2005 · Cited by 494
Glucose transporter protein content and glucose transport capacity in rat skeletal muscles
Henriksen, E. J., Bourey, R. E., Rodnick, K. J., Koranyi, L. I., Permutt, M. A., & Holloszy, J. O. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.4.e593 · Cited by 432
Exercise regulation of glucose transport in skeletal muscle.
Hayashi, T., Wojtaszewski, J., & Goodyear, L. (1997) · American Journal of Physiology · doi:10.1152/ajpendo.1997.273.6.e1039 · Cited by 394
Insulin signaling and insulin sensitivity after exercise in human skeletal muscle
Wojtaszewski, J. F., Hansen, B. F., Gade, Kiens, B., Markuns, J. F., Goodyear, L. J., & Richter, E. A. (2000) · Diabetes · doi:10.2337/diabetes.49.3.325 · Cited by 382
Self-citation
Insulin action and insulin resistance in human skeletal muscle
Zierath, J. R., Krook, A., & Wallberg-Henriksson, H. (2000) · Diabetologia · doi:10.1007/s001250051457 · Cited by 367
The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia
Sylow, L., Tokarz, V. L., Richter, E. A., & Klip, A. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.03.020 · Cited by 366
Self-citation
Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance
Hawley, J. A. (2004) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.505 · Cited by 344
Muscle Glycogen Synthesis Before and After Exercise
Ivy, J. L. (1991) · Sports Medicine · doi:10.2165/00007256-199111010-00002 · Cited by 316
Interleukin-6 depletion selectively improves hepatic insulin action in obesity.
Klover, P. J., Clementi, A. H., & Mooney, R. A. (2005) · Endocrinology · doi:10.1210/en.2004-1468 · Cited by 273
Increased dependence on blood glucose after acclimatization to 4,300 m
Brooks, G. A., Butterfield, G. E., Wolfe, R. R., Groves, B. Μ., Mazzeo, R. S., Sutton, J. R., Wolfel, E. E., & Reeves, J. Τ. (1991) · Journal of Applied Physiology · doi:10.1152/jappl.1991.70.2.919 · Cited by 270
Glycogen-Dependent Effects of 5-Aminoimidazole-4-Carboxamide (AICA)-Riboside on AMP-Activated Protein Kinase and Glycogen Synthase Activities in RatSkeletal Muscle
Wojtaszewski, J. F. P., Jørgensen, S. B., Hellsten, Y., Hardie, D. G., & Richter, E. A. (2002) · Diabetes · doi:10.2337/diabetes.51.2.284 · Cited by 261
Self-citation
Glucose, exercise and insulin: emerging concepts
Richter, E. A., Derave, W., & Wojtaszewski, J. F. P. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.t01-2-00313.x · Cited by 258
Self-citation
Physical training and insulin sensitivity
Koivisto, V. A., Yki‐Järvinen, H., & DeFronzo, R. A. (1986) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610010407 · Cited by 257
Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle
Widegren, U., Jiang, X. J., Krook, A., Chibalin, A., Björnholm, M., Tally, M., Roth, R. A., Henriksson, J., Wallberg‐Henriksson, H., & Zierath, J. R. (1998) · The FASEB Journal · doi:10.1096/fasebj.12.13.1379 · Cited by 248
Postexercise nutrient intake timing in humans is critical to recovery of leg glucose and protein homeostasis
Levenhagen, D. K., Gresham, J. D., Carlson, M. G., Maron, D. J., Borel, M. J., & Flakoll, P. J. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.6.e982 · Cited by 239
Influence of pre‐exercise muscle glycogen content on exercise‐induced transcriptional regulation of metabolic genes
Pilegaard, H., Keller, C., Steensberg, A., Wulff Helge, J., Klarlund Pedersen, B., Saltin, B., & Neufer, P. D. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.016832 · Cited by 234
Nutritional Strategies to Promote Postexercise Recovery
Beelen, M., Burke, L. M., Gibala, M. J., & van Loon, L. J. C. (2010) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.20.6.515 · Cited by 233
Obesity and insulin resistance: Lessons learned from the Pima indians
Lillioja, S., & Bogardus, C. (1988) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610040508 · Cited by 203
Exercise and insulin cause GLUT-4 translocation in human skeletal muscle
Thorell, A., Hirshman, M. F., Nygren, J., Jorfeldt, L., Wojtaszewski, J. F. P., Dufresne, S. D., Horton, E. S., Ljungqvist, O. H., & Goodyear, L. J. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.4.e733 · Cited by 193
The effect of moderate exercise on postprandial glucose homeostasis in NIDDM patients
Larsen, J. J. S., Dela, F., Kjær, M., & Galbo, H. (1997) · Diabetologia · doi:10.1007/s001250050699 · Cited by 183
Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle
Pehmøller, C., Treebak, J. T., Birk, J. B., Chen, S., MacKintosh, C., Hardie, D. G., Richter, E. A., & Wojtaszewski, J. F. P. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00115.2009 · Cited by 171
Self-citation
Effect of Oral Creatine Supplementation on Human Muscle GLUT4 Protein Content After Immobilization
Eijnde, B. O. '., Ursø, B., Richter, E. A., Greenhaff, P. L., & Hespel, P. (2001) · Diabetes · doi:10.2337/diabetes.50.1.18 · Cited by 162
Self-citation
Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise
Pilegaard, H., Osada, T., Andersen, L. T., Helge, J. W., Saltin, B., & Neufer, P. D. (2005) · Metabolism · doi:10.1016/j.metabol.2005.03.008 · Cited by 154
Regulation of glucose transport into skeletal muscle
Holloszy, J. O., & Hansen, P. A. (1996) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/3-540-61343-9_8 · Cited by 151
Muscle glycogen resynthesis during recovery from cycle exercise: no effect of additional protein ingestion
van Hall, G., Shirreffs, S. M., & Calbet, J. A. L. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.5.1631 · Cited by 147
Glycogen synthase localization and activity in rat skeletal muscle is strongly dependent on glycogen content
Nielsen, J. N., Derave, W., Kristiansen, S., Ralston, E., Ploug, T., & Richter, E. A. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.0757h.x · Cited by 138
Self-citation
Prior AICAR Stimulation Increases Insulin Sensitivity in Mouse Skeletal Muscle in an AMPK-Dependent Manner
Kjøbsted, R., Treebak, J. T., Fentz, J., Lantier, L., Viollet, B., Birk, J. B., Schjerling, P., Björnholm, M., Zierath, J. R., & Wojtaszewski, J. F. P. (2014) · Diabetes · doi:10.2337/db14-1402 · Cited by 135
Regulation of GLUT4 protein and glycogen synthase during muscle glycogen synthesis after exercise
IVY, J. L., & KUO, C. ‐. (1998) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.1998.0302e.x · Cited by 129
Factors affecting clinical assessment of insulin sensitivity in horses
Firshman, A. M., & Valberg, S. J. (2007) · Equine Veterinary Journal · doi:10.2746/042516407x238512 · Cited by 129
Role of interleukin‐6 signalling in glucose and lipid metabolism
Glund, S., & Krook, A. (2007) · Acta Physiologica · doi:10.1111/j.1748-1716.2007.01779.x · Cited by 129
Exercise‐induced overexpression of key regulatory proteins involved in glucose uptake and metabolism in tetraplegic persons: molecular mechanism for improved glucose homeostasis
Hjeltnes, N., Galuska, D., Björnholm, M., Aksnes, A.-K., Lannem, A. M., Zierath, J. R., & Wallberg‐Henriksson, H. (1998) · The FASEB Journal · doi:10.1096/fasebj.12.15.1701 · Cited by 121
Potential role of TBC1D4 in enhanced post-exercise insulin action in human skeletal muscle
Treebak, J. T., Frøsig, C., Pehmøller, C., Chen, S., Maarbjerg, S. J., Brandt, N., MacKintosh, C., Zierath, J. R., Hardie, D. G., Kiens, B., et al. (2009) · Diabetologia · doi:10.1007/s00125-009-1294-y · Cited by 119
Self-citation
Improved insulin sensitivity after exercise: focus on insulin signaling
Frøsig, C., & Richter, E. A. (2009) · Obesity · doi:10.1038/oby.2009.383 · Cited by 116
Self-citation
Acute exercise increases the number of plasma membrane glucose transporters in rat skeletal muscle
Hirshman, M. F., Wallberg‐Henriksson, H., Wardzala, L. J., Horton, E. D., & Horton, E. S. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80486-1 · Cited by 113
The effect of intense exercise on postprandial glucose homeostasis in type II diabetic patients
Larsen, J. J. S., Dela, F., Madsbad, S., & Galbo, H. (1999) · Diabetologia · doi:10.1007/s001250051440 · Cited by 112
Strategies to Enhance Fat Utilisation During Exercise
Hawley, J. A., Brouns, F. J. P. H., & Jeukendrup, A. E. (1998) · Sports Medicine · doi:10.2165/00007256-199825040-00003 · Cited by 112
Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle.
Wojtaszewski, J. F. P., & Richter, E. A. (2006) · Essays in Biochemistry · doi:10.1042/bse0420031 · Cited by 109
Self-citation
Current understanding of increased insulin sensitivity after exercise – emerging candidates
Maarbjerg, S. J., Sylow, L., & Richter, E. A. (2011) · Acta Physiologica · doi:10.1111/j.1748-1716.2011.02267.x · Cited by 104
Self-citation
Wortmannin inhibits both insulin- and contraction-stimulated glucose uptake and transport in rat skeletal muscle
Wojtaszewski, J. F. P., Hansen, B. F., Ursø, B., & Richter, E. A. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.4.1501 · Cited by 104
Self-citation
DIET AND EXERCISE IN TYPE 2 DIABETES MELLITUS
Hamdy, O., Goodyear, L. J., & Horton, E. S. (2001) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70220-6 · Cited by 102
Exercise Alleviates Lipid-Induced Insulin Resistance in Human Skeletal Muscle–Signaling Interaction at the Level of TBC1 Domain Family Member 4
Pehmøller, C. K., Brandt, N., Birk, J. B., Høeg, L. D., Sjøberg, K. A., Goodyear, L. J., Kiens, B., Richter, E. A., & Wojtaszewski, J. F. P. (2012) · Diabetes · doi:10.2337/db11-1572 · Cited by 106
Self-citation
Effect of fiber type and nutritional state on AICAR- and contraction-stimulated glucose transport in rat muscle
Ai, H., Ihlemann, J., Hellsten, Y., Lauritzen, H. P. M. M., Hardie, D. G., Galbo, H., & Ploug, T. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00167.2001 · Cited by 105
Regulation of glucose transport in skeletal muscle 1
Barnard, R. J., & YOUNGREN, J. F. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.14.1426762 · Cited by 100
Interactions between insulin and exercise
Richter, E. A., Sylow, L., & Hargreaves, M. (2021) · Biochemical Journal · doi:10.1042/bcj20210185 · Cited by 99
Self-citation
Enhancement of whole body glucose uptake during and after human skeletal muscle low-frequency electrical stimulation
Hamada, T., Sasaki, H., Hayashi, T., Moritani, T., & Nakao, K. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00486.2002 · Cited by 96
Utilization of lipids during exercise in human subjects: metabolic and dietary constraints
Brouns, F. J. P. H., & Vusse, G. J. (1998) · British Journal Of Nutrition · doi:10.1079/bjn19980022 · Cited by 93
Regulation of GLUT4 protein expression and glycogen storage after prolonged exercise
KUO, BROWNING, & IVY (1999) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.1999.00489.x · Cited by 89
Activation of glucose transport in muscle by exercise
Holloszy, J. O., Constable, S. H., & Young, D. A. (1986) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610010405 · Cited by 87
Role of 5′AMP‐activated protein kinase in glycogen synthase activity and glucose utilization: insights from patients with McArdle's disease
Nielsen, J. N., Wojtaszewski, J. F. P., Haller, R. G., Hardie, D. G., Kemp, B. E., Richter, E. A., & Vissing, J. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.018044 · Cited by 86
Self-citation
Increased submaximal insulin-stimulated glucose uptake in mouse skeletal muscle after treadmill exercise
Hamada, T., Arias, E. B., & Cartee, G. D. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00416.2006 · Cited by 84
The Role of Skeletal Muscle in Glucose Transport, Glucose Homeostasis, and Insulin Resistance: Implications for Physical Therapy
Sinacore, D. R., & Gulve, E. A. (1993) · Physical Therapy · doi:10.1093/ptj/73.12.878 · Cited by 87
Postexercise glucose uptake and glycogen synthesis in skeletal muscle from GLUT4‐deficient mice
Ryder, J. W., Kawano, Y., Galuska, D., Fahlman, R., Wallberg‐Henriksson, H., Charron, M. J., & Zierath, J. R. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.15.2246 · Cited by 83
Contraction-induced skeletal muscle FAT/CD36 trafficking and FA uptake is AMPK independent
Jeppesen, J. F., Albers, P. H., Rose, A. J., Birk, J. B., Schjerling, P., Dzamko, N. L., Steinberg, G. R., & Kiens, B. (2011) · Journal of Lipid Research · doi:10.1194/jlr.m007138 · Cited by 83
Exercise and physical training: Effects on insulin sensitivity and glucose metabolism
Horton, E. S. (1986) · Diabetes/Metabolism Reviews · doi:10.1002/dmr.5610020101 · Cited by 78
NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise.
Price, T. B., Perseghin, G., Dulęba, A. J., Chen, W., Chase, J. R., Rothman, D. L., Shulman, R. G., & Shulman, G. I. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5329 · Cited by 77
Effect of prior exercise on the partitioning of an intestinal glucose load between splanchnic bed and skeletal muscle.
Hamilton, K. S., Gibbons, F. K., Bracy, D. P., Lacy, D. B., Cherrington, A. D., & Wasserman, D. H. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118756 · Cited by 75
Effect of acute activation of 5′-AMP-activated protein kinase on glycogen regulation in isolated rat skeletal muscle
Miyamoto, L., Toyoda, T., Hayashi, T., Yonemitsu, S., Nakano, M., Tanaka, S., Ebihara, K., Masuzaki, H., Hosoda, K., Ogawa, Y., et al. (2007) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01034.2006 · Cited by 72
Regulation of muscle glycogen repletion, muscle protein synthesis and repair following exercise.
Ivy, J. L. (2004) · Europe PMC (PubMed Central) · Cited by 72
Insulin signalling: effects of prior exercise
Wojtaszewski, J. F. P., Jørgensen, S. B., Frøsig, C., MacDonald, C., Birk, J. B., & Richter, E. A. (2003) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01151.x · Cited by 69
Self-citation
Effects of feeding meals with various soluble-carbohydrate content on muscle glycogen synthesis after exercise in horses
Lacombe, V. A., Hinchcliff, K. W., Kohn, C. W., Devor, S. T., & Taylor, L. E. (2004) · American Journal of Veterinary Research · doi:10.2460/ajvr.2004.65.916 · Cited by 65
A comprehensive view of muscle glucose uptake: regulation by insulin, contractile activity, and exercise
Richter, E. A., Bilan, P. J., & Klip, A. (2025) · Physiological Reviews · doi:10.1152/physrev.00033.2024 · Cited by 64
Self-citation
Are the reductions in triacylglycerol and insulin levels after exercise related?
Gill, J. M. R., Herd, S. L., TSETSONIS, N. V., & Hardman, A. E. (2002) · Clinical Science · doi:10.1042/cs1020223 · Cited by 63
Effect of insulin and contraction up on glucose transport in skeletal muscle
Pereira, L. O., & Lancha, A. H. (2003) · Progress in Biophysics and Molecular Biology · doi:10.1016/s0079-6107(03)00055-5 · Cited by 65
Exercise Intensity Modulates Glucose-Stimulated Insulin Secretion when Adjusted for Adipose, Liver and Skeletal Muscle Insulin Resistance
Malin, S. K., Rynders, C. A., Weltman, J. Y., Barrett, E. J., & WELTMAN, A. L. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154063 · Cited by 61
Exercise, Hypoglycemia, and Type 1 Diabetes
Basu, R., Johnson, M. L., Kudva, Y. C., & Basu, A. (2014) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2014.0097 · Cited by 60
Increased insulin receptor signaling and glycogen synthase activity contribute to the synergistic effect of exercise on insulin action
Christ-Roberts, C. Y., Pratipanawatr, T., Pratipanawatr, W., Berria, R., Belfort, R., & Mandarino, L. J. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00605.2003 · Cited by 55
Exercise and Glycemic Control: Focus on Redox Homeostasis and Redox-Sensitive Protein Signaling
Parker, L., Shaw, C. S., Stepto, N. K., & Levinger, I. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00087 · Cited by 55
Metabolic Responses to Exercise: Effects of endurance training and implications for diabetes
Richter, E. A., Turcotte, L. P., Hespel, P., & Kiens, B. (1992) · Diabetes Care · doi:10.2337/diacare.15.11.1767 · Cited by 54
Self-citation
Current advances in our understanding of exercise as medicine in metabolic disease
Sylow, L., & Richter, E. A. (2019) · Current Opinion in Physiology · doi:10.1016/j.cophys.2019.04.008 · Cited by 54
Self-citation
Regulation of glycogen synthesis in rat skeletal muscle after glycogen-depleting contractile activity: effects of adrenaline on glycogen synthesis and activation of glycogen synthase and glycogen phosphorylase
Franch, J., Aslesen, R., & Jensen, J. (1999) · Biochemical Journal · doi:10.1042/bj3440231 · Cited by 54
Exercise training reduces the insulin‐sensitizing effect of a single bout of exercise in human skeletal muscle
Steenberg, D. E., Jørgensen, N. B., Birk, J. B., Sjøberg, K. A., Kiens, B., Richter, E. A., & Wojtaszewski, J. F. P. (2018) · The Journal of Physiology · doi:10.1113/jp276735 · Cited by 53
Self-citation
Acute effects of the β3‐adrenoceptor agonist, BRL 35135, on tissue glucose utilisation
Liu, Y., & Stock, M. J. (1995) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1995.tb13287.x · Cited by 52
Insulin-Induced Redistribution of GLUT4 Glucose Carriers in the Muscle Fiber: In Search of GLUT4 Trafficking Pathways
Zorzano, A., Muñoz, P., Camps, M., Mora, C., Testar, X., & Palacı́n, M. (1996) · Diabetes · doi:10.2337/diab.45.1.s70 · Cited by 51
Effect of glycogen synthase overexpression on insulin-stimulated muscle glucose uptake and storage
Fogt, D. L., Pan, S., Lee, S., Ding, Z., Scrimgeour, A. G., Lawrence, J. C., & Ivy, J. L. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00115.2003 · Cited by 48
The adjustment of diet and insulin dose during long-term endurance exercise in Type 1 (insulin-dependent) diabetic men
Sane, T., Helve, E., Pelkonen, R., & Koivisto, V. A. (1988) · Diabetologia · doi:10.1007/bf00279130 · Cited by 48
Resistance exercise and postprandial lipemia: the dose effect of differing volumes of acute resistance exercise bouts
Shannon, K. A., Shannon, R. M., Clore, J. N., Gennings, C., Warren, B. J., & Potteiger, J. A. (2005) · Metabolism · doi:10.1016/j.metabol.2005.01.017 · Cited by 48
Carbohydrate and Fluid Needs of the Soccer Player
Shephard, R. J., & Leatt, P. (1987) · Sports Medicine · doi:10.2165/00007256-198704030-00002 · Cited by 47
Energy at High Altitude
Hill, N. E., Stacey, M. J., & Woods, D. R. (2011) · Journal of the Royal Army Medical Corps · doi:10.1136/jramc-157-01-08 · Cited by 42
Glucose uptake and metabolic stress in rat muscles stimulated electrically with different protocols
Aslesen, R., Engebretsen, E. M. L., Franch, J., & Jensen, J. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.3.1237 · Cited by 42
Blood glucose clearance after feeding and exercise in polysaccharide storage myopathy
Côrte, F. D. D. L., Valberg, S. J., Mickelson, J. R., & HOWER‐MORITZ, M. A. (1999) · Equine Veterinary Journal · doi:10.1111/j.2042-3306.1999.tb05242.x · Cited by 42
The acute vs. chronic effect of exercise on insulin sensitivity: nothing lasts forever
DiMenna, F. J., & Arad, A. D. (2020) · Cardiovascular Endocrinology & Metabolism · doi:10.1097/xce.0000000000000239 · Cited by 46
The Relationship between Exercise, Nutrition and Type 2 Diabetes
Stephenson, E. J., Smiles, W. J., & Hawley, J. A. (2014) · Medicine and sport science/Medicine and sport · doi:10.1159/000357331 · Cited by 42
Effects of contraction on localization of GLUT4 and v-SNARE isoforms in rat skeletal muscle
Rose, A. J., Jeppesen, J. F., Kiens, B., & Richter, E. A. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00258.2009 · Cited by 40
Self-citation
Electro-acupuncture improves responsiveness to insulin via excitation of somatic afferent fibers in diabetic rats
Higashimura, Y., Shimoju, R., Maruyama, H., & Kurosawa, M. (2009) · Autonomic Neuroscience · doi:10.1016/j.autneu.2009.06.003 · Cited by 40
Impact of caffeine and protein on postexercise muscle glycogen synthesis
BEELEN, M., VAN KRANENBURG, J., SENDEN, J. M., KUIPERS, H., & VAN LOON, L. J. C. (2012) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31823a40ef · Cited by 39
Hormonal regulation of the rate of the glycogen/glucose‐1‐phosphate cycle in skeletal muscle
Challiss, R. A. J., Crabtree, B., & Newsholme, E. A. (1987) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1987.tb10756.x · Cited by 39
Postmeal exercise blunts postprandial glucose excursions in people on metformin monotherapy
Erickson, M. L., Little, J. P., Gay, J. L., McCully, K. K., & Jenkins, N. T. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00213.2017 · Cited by 40
Increased insulin‐stimulated glucose uptake by exercised human muscles one day after prolonged physical exercise
Annuzzi, G., Riccardi, G., Capaldo, B., & Kauser, L. (1991) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.1991.tb01351.x · Cited by 36
Interactions of substrate availability, exercise performance, and nutrition with muscle glycogen metabolism in horses
Lacombe, V. A., Hinchcliff, K. W., & Taylor, L. E. (2003) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.2003.223.1576 · Cited by 36
Impact of glutamine supplementation on glucose homeostasis during and after exercise
Iwashita, S., Williams, P. J., Jabbour, K., Ueda, T., Kobayashi, H., Baier, S. M., & Flakoll, P. J. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00305.2005 · Cited by 36
Regulation and function of Ca2+–calmodulin‐dependent protein kinase II of fast‐twitch rat skeletal muscle
Rose, A. J., Alsted, T. J., Kobberø, J. B., & Richter, E. A. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2006.127464 · Cited by 35
Self-citation
Prior exercise increases net hepatic glucose uptake during a glucose load
Galassetti, P. R., Coker, R. H., Lacy, D. B., Cherrington, A. D., & Wasserman, D. H. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.276.6.e1022 · Cited by 36
The effects of interval- vs. continuous exercise on excess post-exercise oxygen consumption and substrate oxidation rates in subjects with type 2 diabetes
Karstoft, K., Wallis, G. A., Pedersen, B. K., & Solomon, T. P. J. (2016) · Metabolism · doi:10.1016/j.metabol.2016.05.017 · Cited by 35
Angiotensin-(1-7) Participates in Enhanced Skeletal Muscle Insulin Sensitivity After a Bout of Exercise
Echeverría‐Rodríguez, O., Gallardo‐Ortíz, I. A., del Valle‐Mondragón, L., & Villalobos‐Molina, R. (2020) · Journal of the Endocrine Society · doi:10.1210/jendso/bvaa007 · Cited by 35
Glucose and Amino Acid Uptake by Exercising Musclesin Vivo: Effect of Insulin, Fiber Population, and Denervation*
Turinsky, J. (1987) · Endocrinology · doi:10.1210/endo-121-2-528 · Cited by 35
Proteomics of Skeletal Muscle: Focus on Insulin Resistance and Exercise Biology
Deshmukh, A. S. (2016) · Proteomes · doi:10.3390/proteomes4010006 · Cited by 35
Early dietary intervention with structured triacylglycerols containing docosahexaenoic acid. Effect on brain, liver, and adipose tissue lipids
Christensen, M. M., & Høy, C. (1997) · Lipids · doi:10.1007/s11745-997-0023-2 · Cited by 34
Effect of insulin on protein synthesis and degradation in skeletal muscle after exercise
Balon, T. W., Zorzano, A., Treadway, J. L., Goodman, M. N., & Ruderman, N. B. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.258.1.e92 · Cited by 33
Self-citation

Authors: Richter, E. A., Garetto, L. P., Goodman, M. N., & Ruderman, N. B.
ORCID: Richter, E. A.
Ruderman, N. B.
Venue: American Journal of Physiology-Endocrinology and Metabolism
Publisher: American Physiological Society
Published: 1984-06-01
Volume: 246
Issue: 6
Pages: E476-E482
ISSN: 0193-1849 (ISSN-L)
1522-1555
DOI: 10.1152/ajpendo.1984.246.6.e476
OpenAlex: W2181090774
Cited by: 194
References: 17
Citations by year: 2025: 1 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 4 · 2019: 2 · 2018: 3 · 2017: 4 · 2016: 8 · 2015: 4 · 2014: 9 · 2013: 3 · 2012: 5
FWCI: 2.13
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Physiology-Endocrinology and Metabolism (publishedVersion)
PubMed (publishedVersion)
Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords: muscle glucose metabolism, glycogen repletion, skeletal muscle, insulin, physical activity, neuromuscular electrical stimulation, glycogen synthesis, glucose uptake, local factors, 2-deoxyglucose, 3-O-methylglucose
MeSH terms: Adenosine Triphosphate, Animals, Deoxyglucose, Electric Stimulation, Glucose, Glycogen, Glycogen Synthase, Hindlimb, Insulin, Male, Motor Activity, Muscles, Phosphocreatine, Rats, Inbred Strains, Rats, In Vitro Techniques

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Enhanced muscle glucose metabolism after exercise: modulation by local factors

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks