Ruderman, Neil B.

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

Hirschey, M. D., Shimazu, T., Goetzman, E., Jing, E., Schwer, B., Lombard, D. B., Grueter, C. A., Harris, C., Biddinger, S., Ilkayeva, O. R., et al. (2010) · Nature

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 1,687

Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α

Itani, S. I., Ruderman, N. B., Schmieder, F., & Boden, G. (2002) · Diabetes

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,390

Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: Acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation

Tomas, E., Tsao, T.-S., Saha, A. K., Murrey, H. E., Zhang, C. C., Itani, S. I., Lodish, H. F., & Ruderman, N. B. (2002) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 973

AMPK and SIRT1: a long-standing partnership?

Ruderman, N. B., Julia Xu, X., Nelson, L., Cacicedo, J. M., Saha, A. K., Lan, F., & Ido, Y. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Sirtuins and Resveratrol in MedicineMetabolism, Diabetes, and Cancer

Cited by 903

The metabolically obese, normal-weight individual revisited.

Ruderman, N., Chisholm, D., Pi-Sunyer, X., & Schneider, S. (1998) · Diabetes

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 893

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

Lan, F., Cacicedo, J. M., Ruderman, N., & Ido, Y. (2008) · Journal of Biological Chemistry

Sirtuins and Resveratrol in MedicineMetabolism, Diabetes, and Cancer

Cited by 825

The “metabolically-obese,” normal-weight individual

Ruderman, N. B., Schneider, S. H., & Berchtold, P. (1981) · The American Journal of Clinical Nutrition

Diabetes, Cardiovascular Risks, and LipoproteinsObesity, Physical Activity, Diet

Cited by 545

Free Fatty Acids Produce Insulin Resistance and Activate the Proinflammatory Nuclear Factor-κB Pathway in Rat Liver

Boden, G., She, P., Mozzoli, M., Cheung, P., Gumireddy, K., Reddy, P., Xiang, X., Luo, Z., & Ruderman, N. (2005) · Diabetes

Liver Disease Diagnosis and TreatmentDiet, Metabolism, and Disease

Cited by 528

Muscle Glucose Metabolism following Exercise in the Rat

Richter, E. A., Garetto, L. P., Goodman, M. N., & Ruderman, N. B. (1982) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerMuscle metabolism and nutrition

Cited by 510

AMPK and the biochemistry of exercise: implications for human health and disease

Richter, E. A., & Ruderman, N. B. (2009) · Biochemical Journal

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 481

Physical Inactivity Rapidly Induces Insulin Resistance and Microvascular Dysfunction in Healthy Volunteers

Hamburg, N. M., McMackin, C. J., Huang, A. L., Shenouda, S. M., Widlansky, M. E., Schulz, E., Gokce, N., Ruderman, N. B., Keaney, J. F., & Vita, J. A. (2007) · Arteriosclerosis, Thrombosis, and Vascular Biology

Cardiovascular and exercise physiologyCardiovascular Health and Disease Prevention

Cited by 474

AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome

Ruderman, N., & Prentki, M. (2004) · Nature Reviews Drug Discovery

Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors

Cited by 451

AMPK, the metabolic syndrome and cancer

Luo, Z., Saha, A. K., Xiang, X., & Ruderman, N. B. (2005) · Trends in Pharmacological Sciences

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 426

Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle

Vavvas, D., Apazidis, A., Saha, A. K., Gamble, J., Patel, A., Kemp, B. E., Witters, L. A., & Ruderman, N. B. (1997) · Journal of Biological Chemistry

Metabolism, Diabetes, and CancerCancer, Lipids, and Metabolism

Cited by 395

AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats

Iglesias, M. A., Ye, J.-M., Frangioudakis, G., Saha, A. K., Tomas, E., Ruderman, N. B., Cooney, G. J., & Kraegen, E. W. (2002) · Diabetes

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 290

AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise.

Kelly, M., Keller, C., Avilucea, P. R., Keller, P., Luo, Z., Xiang, X., Giralt, M., Hidalgo, J., Saha, A. K., Pedersen, B. K., et al. (2004) · Biochemical and Biophysical Research Communications

Metabolism, Diabetes, and CancerExercise and Physiological Responses

Cited by 289

Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity

Ritov, V. B., Menshikova, E. V., Azuma, K., Wood, R., Toledo, F. G. S., Goodpaster, B. H., Ruderman, N. B., & Kelley, D. E. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 283

Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues

LeBrasseur, N. K., Kelly, M., Tsao, T.-S., Farmer, S. R., Saha, A. K., Ruderman, N. B., & Tomas, E. (2006) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors

Cited by 276

Minireview: Malonyl CoA, AMP-Activated Protein Kinase, and Adiposity

Ruderman, N. B., Saha, A. K., & Kraegen, E. W. (2003) · Endocrinology

Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors

Cited by 266

AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise

Ruderman, N. B., Park, H., Kaushik, V. K., Dean, D., Constant, S., Prentki, M., & Saha, A. K. (2003) · Acta Physiologica Scandinavica

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 217

Enhanced muscle glucose metabolism after exercise: modulation by local factors

Richter, E. A., Garetto, L. P., Goodman, M. N., & Ruderman, N. B. (1984) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerMuscle metabolism and nutrition

Cited by 194

Glucagon-Like Peptide-1 (GLP-1) Analog Liraglutide Inhibits Endothelial Cell Inflammation through a Calcium and AMPK Dependent Mechanism

Krasner, N. M., Ido, Y., Ruderman, N. B., & Cacicedo, J. M. (2014) · PLoS ONE

Diabetes Treatment and ManagementAdipokines, Inflammation, and Metabolic Diseases

Cited by 186

Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA

Oakes, N. D., Bell, K. S., Furler, S. M., Camilleri, S., Saha, A. K., Ruderman, N. B., Chisholm, D. J., & Kraegen, E. W. (1997) · Diabetes

Metabolism, Diabetes, and CancerDiet, Metabolism, and Disease

Cited by 176

Malonyl-coa and carnitine in regulation of fat oxidation in human skeletal muscle during exercise

Roepstorff, C., Halberg, N., Hillig, T., Saha, A. K., Ruderman, N. B., Wojtaszewski, J. F. P., Richter, E. A., & Kiens, B. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Metabolism, Diabetes, and CancerMuscle metabolism and nutrition

Cited by 173