The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Total arterial compliance estimated by stroke volume-to-aortic pulse pressure ratio in humans
Abstract
On the basis of the windkessel model, the stroke volume-to-aortic pulse pressure ratio (SV/PP) has been proposed as an estimate of total arterial compliance, but recent studies have questioned this approximation. Aortic pressure was obtained at rest in 31 adults undergoing cardiac catheterization (47 ± 14 yr): controls ( n = 7), patients with dilated cardiomyopathy ( n = 10), and patients with other cardiac diseases ( n = 14). We calculated PP, mean aortic pressure (MAoP), heart period ( T), SV (thermodilution cardiac output/heart rate), total peripheral resistance ( R), total arterial compliance estimated by area method ( C area), and the time constant of aortic pressure decay in diastole ( RC area). In the overall population ( n = 31), there was no significant difference between SV/PP and C area. SV/PP was linearly related to C area(SV/PP = 0.99 C area+ 0.05; r = 0.98; P < 0.001); the slope and intercept did not differ from unity and zero, respectively. Similar results were obtained in the three subgroups. These results implied that PP/MAoP and T/ RC area were proportionally related ( T/ RC area= 1.18PP/MAoP − 0.07; r = 0.96; P < 0.001). We conclude that for humans at rest 1) SV/PP gave a reliable estimate of C area, and 2) T normalized by the time constant of aortic pressure decay in diastole was proportionally related to PP/MAoP. This last relationship could be considered an aspect of the coupling between the left ventricle and its load.
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Cites
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Pulse pressure—a review of mechanisms and clinical relevance
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Arterial Stiffening With Exercise in Patients With Heart Failure and Preserved Ejection Fraction
Reddy, Y. N. V., Andersen, M. J., Obokata, M., Koepp, K. E., Kane, G. C., Melenovsky, V., Olson, T. P., & Borlaug, B. A. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.05.029 · Cited by 262
Metadata
- Authors
- Chemla, D., Hébert, J.-L., Coirault, C., Zamani, K., Suard, I., Colin, P., & Lecarpentier, Y.
- Venue
- American Journal of Physiology-Heart and Circulatory Physiology
- Publisher
- American Physiological Society
- Published
- 1998-02-01
- Volume
- 274
- Issue
- 2
- Pages
- H500-H505
- ISSN
- 0363-6135 (ISSN-L)
- 1522-1539
- OpenAlex
- W2121513563
- Cited by
- 462
- References
- 28
- FWCI
- 4.45
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chemla, D., Hébert, J.-L., Coirault, C., Zamani, K., Suard, I., Colin, P., & Lecarpentier, Y. (1998). Total arterial compliance estimated by stroke volume-to-aortic pulse pressure ratio in humans. American Journal of Physiology-Heart and Circulatory Physiology. https://doi.org/10.1152/ajpheart.1998.274.2.h500
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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