The spontaneous activity and food intake of rats with hypothalamic lesions
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Spontaneous physical activity is reduced during development of ventromedial hypothalamic obesity and increased fat deposition occurs even with restriction of food intake to that of controls.
“Importantly, spontaneous physical activity is reduced during development of ventromedial hypothalamic obesity and increased fat deposition occurs even with restriction of food intake to that of controls.”
From The carbohydrate-insulin model: A physiological perspective on the obesity pandemic (2021) · cites this paper as [42]
Immediately after injury to the ventromedial hypothalamus, hyperinsulinemia develops without systemic insulin resistance, and sympathetic nervous system tone is decreased.
“Immediately after injury to the ventromedial hypothalamus, hyperinsulinemia develops without systemic insulin resistance, and sympathetic nervous system tone is decreased.”
From The carbohydrate-insulin model: A physiological perspective on the obesity pandemic (2021) · cites this paper as [42]
Body weight could be altered, in either direction, by introducing specific lesions in the hypothalamus in which ventromedial hypothalamic lesions caused obesity and lateral hypothalamic lesions caused leanness.
“body weight could be altered, in either direction, by introducing specific lesions in the hypothalamus in which ventromedial hypothalamic lesions caused obesity and lateral hypothalamic lesions caused leanness (13).”
From Leptin at 14 y of age: an ongoing story (2009) · cites this paper as [13]
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“Lesions of the ventral medial hypothalamus (VMH) increased food intake and induced obesity [6; 7].”
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- Authors
- Hetherington, A. W., & Ranson, S. W.
- Affiliations
- Northwestern University (US)
- Venue
- American Journal of Physiology-Legacy Content
- Publisher
- American Physiological Society
- Published
- 1942-06-01
- Volume
- 136
- Issue
- 4
- Pages
- 609-617
- ISSN
- 0002-9513 (ISSN-L)
- OpenAlex
- W2339362554
- Cited by
- 316
- References
- 0
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 4 · 2022: 3 · 2021: 1 · 2020: 1 · 2019: 5 · 2018: 4 · 2017: 4 · 2016: 5 · 2015: 6 · 2014: 6 · 2013: 4 · 2012: 4
- FWCI
- 1.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physiology-Legacy Content (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- hypothalamus, hypothalamic lesions, spontaneous activity, locomotor activity, dietary intake, feeding behavior, rats
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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