The alphabet of weight control.

Positional cloning of the mouse obese gene and its human homologue

Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419 · see citing works

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Maffei, M., Halaas, J., Ravussin, E., Pratley, R. E., Lee, G. H., Zhang, Y., Fei, H., Kim, S., Lallone, R., Ranganathan, S., et al. (1995) · Nature Medicine · doi:10.1038/nm1195-1155 · Cited by 3,725 · see citing works

Role of leptin in the neuroendocrine response to fasting

Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., & Flier, J. S. (1996) · Nature · doi:10.1038/382250a0 · Cited by 3,117 · see citing works

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

Huszar, D., Lynch, C. A., Fairchild-Huntress, V., Dunmore, J. H., Fang, Q., Berkemeier, L. R., Gu, W., Kesterson, R. A., Boston, B. A., Cone, R. D., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)81865-6 · Cited by 3,030 · see citing works

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

Fan, W., Boston, B. A., Kesterson, R. A., Hruby, V. J., & Cone, R. D. (1997) · Nature · doi:10.1038/385165a0 · Cited by 1,902 · see citing works

The role of neuropeptide Y in the antiobesity action of the obese gene product

Stephens, T. W., Basinski, M., Bristow, P. K., Bue-Valleskey, J. M., Burgett, S. G., Craft, L., Hale, J., Hoffmann, J., Hsiung, H. M., Kriauciunas, A., et al. (1995) · Nature · doi:10.1038/377530a0 · Cited by 1,498 · see citing works

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

Coleman, D. L. (1978) · Diabetologia · doi:10.1007/bf00429772 · Cited by 1,307 · see citing works

Adipogenesis and Obesity: Rounding Out the Big Picture

Spiegelman, B. M., & Flier, J. S. (1996) · Cell · doi:10.1016/s0092-8674(00)81359-8 · Cited by 1,254 · see citing works

Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain

Mountjoy, K. G., Mortrud, M. T., Low, M. J., Simerly, R. B., & Cone, R. D. (1994) · Molecular Endocrinology · doi:10.1210/mend.8.10.7854347 · Cited by 1,157 · see citing works

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

Lu, D., Willard, D. H., Patel, I. R., Kadwell, S. H., Overton, L. K., Kost, T., Luther, M., Chen, W., Woychik, R. P., Wilkison, W. O., et al. (1994) · Nature · doi:10.1038/371799a0 · Cited by 1,075 · see citing works

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

Erickson, J. C., Clegg, K. E., & Palmiter, R. D. (1996) · Nature · doi:10.1038/381415a0 · Cited by 1,009 · see citing works

A receptor subtype involved in neuropeptide-Y-induced food intake

Gerald, C., Walker, M. W., Criscione, L., Gustafson, E. L., Batzl‐Hartmann, C., Smith, K. E., Vaysse, P. J. ‐., Durkin, M. M., Laz, T. M., Linemeyer, D. L., et al. (1996) · Nature · doi:10.1038/382168a0 · Cited by 891 · see citing works

Molecular characterization of the mouse agouti locus

Bultman, S. J., Michaud, E. J., & Woychik, R. P. (1992) · Cell · doi:10.1016/s0092-8674(05)80067-4 · Cited by 805 · see citing works

Attenuation of the Obesity Syndrome of ob/ob Mice by the Loss of Neuropeptide Y

Erickson, J. C., Hollopeter, G., & Palmiter, R. D. (1996) · Science · doi:10.1126/science.274.5293.1704 · Cited by 794 · see citing works

Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity

Zarjevski, N., Cusin, I., Vettor, R., Rohner‐Jeanrenaud, F., & Jeanrenaud, B. (1993) · Endocrinology · doi:10.1210/endo.133.4.8404618 · Cited by 476 · see citing works

The spontaneous activity and food intake of rats with hypothalamic lesions

Hetherington, A. W., & Ranson, S. W. (1942) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1942.136.4.609 · Cited by 316 · see citing works

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R. M., Tanaka, H., Williams, S. C., Richardson, J. A., Kozlowski, G. P., Wilson, S., et al. (1998) · Cell · doi:10.1016/s0092-8674(00)80949-6 · Cited by 5,501 · see citing works

Leptin and the regulation of body weight in mammals

Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405 · see citing works

Distribution of orexin neurons in the adult rat brain

Nambu, T., Sakurai, T., Mizukami, K., Hosoya, Y., Yanagisawa, M., & Goto, K. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01336-0 · Cited by 1,070 · see citing works

Physiological response to long-term peripheral and central leptin infusion in lean and obese mice.

Halaas, J. L., Boozer, C., Blair-West, J., Fidahusein, N., Denton, D. A., & Friedman, J. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.16.8878 · Cited by 1,033 · see citing works

Leptin Increases Hypothalamic Pro-opiomelanocortin mRNA Expression in the Rostral Arcuate Nucleus

Schwartz, M. W., Seeley, R. J., Woods, S. C., Weigle, D. S., Campfield, L. A., Burn, P., & Baskin, D. G. (1997) · Diabetes · doi:10.2337/diab.46.12.2119 · Cited by 879 · see citing works

BDNF regulates eating behavior and locomotor activity in mice

Kernie, S. G., Liebl, D. J., & Parada, L. F. (2000) · The EMBO Journal · doi:10.1093/emboj/19.6.1290 · Cited by 806 · see citing works

Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin

Gong, D., He, Y., Karas, M., & Reitman, M. L. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.39.24129 · Cited by 740 · see citing works

Leptin and the endocrine control of energy balance

Friedman, J. M. (2019) · Nature Metabolism · doi:10.1038/s42255-019-0095-y · Cited by 661 · see citing works

The Function of Leptin in Nutrition, Weight, and Physiology

Friedman, J. M. (2002) · Nutrition Reviews · doi:10.1301/002966402320634878 · Cited by 505 · see citing works

Overexpression of Agrt leads to obesity in transgenic mice

Graham, M., Shutter, J. R., Sarmiento, U. M., Sarosi, L., & Stark, K. L. (1997) · Nature Genetics · doi:10.1038/ng1197-273 · Cited by 387 · see citing works

Leptin, Leptin Receptors, and the Control of Body Weight

Friedman, J. M. (2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1998.tb01685.x · Cited by 372 · see citing works

The Central Melanocortin System and Energy Homeostasis

Cone, R. D. (1999) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(99)00153-8 · Cited by 351 · see citing works

Cardiovascular regulatory actions of the hypocretins in brain

Samson, W. K., Gosnell, B. A., Chang, J.-K., Resch, Z. T., & Murphy, T. C. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01457-2 · Cited by 294 · see citing works

The long road to leptin

Friedman, J. M. (2016) · Journal of Clinical Investigation · doi:10.1172/jci91578 · Cited by 279 · see citing works

Leptin at 14 y of age: an ongoing story

Friedman, J. M. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26788b · Cited by 272 · see citing works

In VitroLipolytic Effect of Leptin on Mouse Adipocytes: Evidence for a Possible Autocrine/Paracrine Role of Leptin

Frühbeck, G., Aguado, M., & Martínez, J. A. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.7716 · Cited by 261 · see citing works

20 YEARS OF LEPTIN: Leptin at 20: an overview

Friedman, J. M. (2014) · Journal of Endocrinology · doi:10.1530/joe-14-0405 · Cited by 249 · see citing works

Hyperleptinemia of Pregnancy Associated with the Appearance of a Circulating Form of the Leptin Receptor

Gavrilova, O., Barr, V. A., Marcus‐Samuels, B., & Reitman, M. L. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.48.30546 · Cited by 246 · see citing works

Independent and Additive Effects of Central POMC and Leptin Pathways on Murine Obesity

Boston, B. A., Blaydon, K. M., Varnerin, J. P., & Cone, R. D. (1997) · Science · doi:10.1126/science.278.5343.1641 · Cited by 239 · see citing works

The Physiology of Body Weight Regulation: Relevance to the Etiology of Obesity in Children

ROSENBAUM, M. S., & Leibel, R. L. (1998) · PEDIATRICS · doi:10.1542/peds.101.s2.525 · Cited by 229 · see citing works

Starvation: Early Signals, Sensors, and Sequelae1

Dallman, M. F., Akana, S. F., Bhatnagar, S., Bell, M. E., Choi, S., Chu, A., Horsley, C. J., Levin, N., Meijer, O. C., Soriano, L., et al. (1999) · Endocrinology · doi:10.1210/endo.140.9.7001 · Cited by 226 · see citing works

GABA-mediated inhibition of raphe pallidus neurons regulates sympathetic outflow to brown adipose tissue

Morrison, S. F., Sved, A. F., & Passerin, A. M. (1999) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1999.276.2.r290 · Cited by 217 · see citing works

Obesity in Patients with Craniopharyngioma: Assessment of Food Intake and Movement Counts Indicating Physical Activity

Harz, K. J., Müller, H. L., Waldeck, E., Pudel, V., & Roth, C. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021797 · Cited by 214 · see citing works

Plasma Leptin Is Related to Proinflammatory Status and Dietary Intake in Patients with Chronic Obstructive Pulmonary Disease

Schols, A. M. W. J., Creutzberg, E. C., Buurman, W. A., CAMPFIELD, L. A., Saris, W. H. M., & Wouters, E. F. �. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.4.9811033 · Cited by 214 · see citing works

Effects of mutations in the human uncoupling protein 3 gene on the respiratory quotient and fat oxidation in severe obesity and type 2 diabetes.

Argyropoulos, G. A., Brown, A. M., Willi, S. M., Zhu, J., He, Y., Reitman, M. L., Gevao, S. M., Spruill, I. J., & Garvey, W. T. (1998) · Journal of Clinical Investigation · doi:10.1172/jci4115 · Cited by 202 · see citing works

Leptin: in search of role(s) in human physiology and pathophysiology

Mantzoros, C. S., & Moschos, S. J. (1998) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1998.00571.x · Cited by 196 · see citing works

Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain

Lin, S., Storlien, L. H., & Huang, X. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02580-4 · Cited by 194 · see citing works

Identification of a Placental Enhancer for the Human Leptin Gene

Bi, S., Gavrilova, O., Gong, D.-W., Mason, M. M., & Reitman, M. L. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.48.30583 · Cited by 186 · see citing works

Cloning of rat uncoupling protein‐3 and uncoupling protein‐2 cDNAs: their gene expression in rats fed high‐fat diet

Matsuda, J., Hosoda, K., Itoh, H., Son, C., Doi, K., Tanaka, T., Fukunaga, Y., Inoue, G., Nishimura, H., Yoshimasa, Y., et al. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)01381-1 · Cited by 186 · see citing works

Leptin Attenuates Cardiac Contraction in Rat Ventricular Myocytes

Nickola, M. W., Wold, L. E., Colligan, P. B., Wang, G., Samson, W. K., & Ren, J. T. (2000) · Hypertension · doi:10.1161/01.hyp.36.4.501 · Cited by 184 · see citing works

CNS regulation of appetite

Harrold, J. A., Dovey, T. M., Blundell, J. E., & Halford, J. C. G. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.01.007 · Cited by 177 · see citing works

Role of adipokines in complications related to obesity. A review

Gnacińska, M., Małgorzewicz, S., Stojek, M., Łysiak-Szydłowska, W., & Sworczak, K. (2009) · Advances in Medical Sciences · doi:10.2478/v10039-009-0035-2 · Cited by 177 · see citing works

Longitudinal Analysis of Maternal Serum Leptin Levels during Pregnancy, at Birth and Up To Six Weeks after Birth: Relation to Body Mass Index, Skinfolds, Sex Steroids and Umbilical Cord Blood Leptin Levels

Schubring, C., Englaro, P., Siebler, T., Blum, W. F., Demirakça, T., Kratzsch, J., & Kiess, W. (1998) · Hormone Research in Paediatrics · doi:10.1159/000023290 · Cited by 169 · see citing works

Is There an Association Between Sweetened Beverages and Adiposity?

Bachman, C., Baranowski, T., & Nicklas, T. A. (2006) · Nutrition Reviews · doi:10.1111/j.1753-4887.2006.tb00199.x · Cited by 168 · see citing works

Obesity: An overview on its current perspectives and treatment options

Nammi, S., Koka, S., Chinnala, K. M., & Boini, K. M. (2004) · Nutrition Journal · doi:10.1186/1475-2891-3-3 · Cited by 163 · see citing works

Leptin and the Regulation of Body Weigh

Friedman, J. M. (2011) · The Keio Journal of Medicine · doi:10.2302/kjm.60.1 · Cited by 164 · see citing works

Control of food intake by fatty acid oxidation and ketogenesis

Scharrer, E. (1999) · Nutrition · doi:10.1016/s0899-9007(99)00125-2 · Cited by 157 · see citing works

Central Leptin Acutely Reverses Diet-Induced Hepatic Insulin Resistance

Pocai, A., Morgan, K., Buettner, C., Gutierrez-Juarez, R., Obici, S., & Rossetti, L. (2005) · Diabetes · doi:10.2337/diabetes.54.11.3182 · Cited by 153 · see citing works

A role for NPY overexpression in the dorsomedial hypothalamus in hyperphagia and obesity of OLETF rats

Bi, S., Ladenheim, E. E., Schwartz, G. J., & Moran, T. H. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.281.1.r254 · Cited by 153 · see citing works

Suppression of food intake and growth by amino acids in Drosophila: the role of pumpless, a fat body expressed gene with homology to vertebrate glycine cleavage system

Zinke, I., Kirchner, C., Chao, L. C., Tetzlaff, M. T., & Pankratz, M. J. (1999) · Development · doi:10.1242/dev.126.23.5275 · Cited by 151 · see citing works

A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls.

Stunff, C. L., Bihan-Benjamin, C. L., Schork, N. J., & Bougneres, P. F. (2000) · Diabetes · doi:10.2337/diabetes.49.12.2196 · Cited by 146 · see citing works

Cytokines and STAT Signaling

Schindler, C., & Strehlow, I. (1999) · Advances in pharmacology · doi:10.1016/s1054-3589(08)60111-8 · Cited by 129 · see citing works

Type 2 Diabetes: How Much of an Autoimmune Disease?

de Candia, P., Prattichizzo, F., Garavelli, S., Rosa, V. D., Galgani, M., Rella, F. D., Spagnuolo, M. I., Colamatteo, A., Fusco, C., Micillo, T., et al. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00451 · Cited by 118 · see citing works

Photo-neuroendocrine control of seasonal cycles in body weight, pelage growth and reproduction: lessons from the HPD sheep model

Lincoln, G. A., & Richardson, M. C. (1998) · Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology · doi:10.1016/s0742-8413(98)00017-6 · Cited by 120 · see citing works

Chronic Stress and Energy Balance: Role of the Hypothalamo‐Pituitary‐Adrenal Axis

Dallman, M. F., & Bhatnagar, S. (2001) · Comprehensive physiology · doi:10.1002/cphy.cp070410 · Cited by 117 · see citing works

Serum Leptin Levels in Male Marathon Athletes before and after the Marathon Run

Leal‐Cerro, A., García‐Luna, P. P., Astorga, R., Parejo, J., Peino, R., Diéguez, C., & Casanueva, F. F. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.7.4959 · Cited by 120 · see citing works

Adipose tissue and reproductive health

Mathew, H., Castracane, V. D., & Mantzoros, C. S. (2017) · Metabolism · doi:10.1016/j.metabol.2017.11.006 · Cited by 109 · see citing works

Obesity: Pathophysiology and Clinical Management

Gurevich-Panigrahi, T., Panigrahi, S., Wiecheć, E., & Łoś, M. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709787315568 · Cited by 109 · see citing works

Polycystic ovarian disease: heritability and heterogeneity

Crosignani, P. G. (2001) · Human Reproduction Update · doi:10.1093/humupd/7.1.3 · Cited by 105 · see citing works

Increased Uncoupling Protein2 mRNA in White Adipose Tissue, and Decrease in Leptin, Visceral Fat, Blood Glucose, and Cholesterol in KK-AyMice Fed with Eicosapentaenoic and Docosahexaenoic Acids in Addition to Linolenic Acid

Hun, C. S., Hasegawa, K., Kawabata, T., Kato, M., Shimokawa, T., & Kagawa, Y. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.0733 · Cited by 90 · see citing works

20 years of leptin: From the discovery of the leptin gene to leptin in our therapeutic armamentarium

Friedman, J. M., & Mantzoros, C. S. (2014) · Metabolism · doi:10.1016/j.metabol.2014.10.023 · Cited by 89 · see citing works

Leptin serum concentrations in healthy neonates within the first week of life: relation to insulin and growth hormone levels, skinfold thickness, body mass index and weight

Schubring, C., Siebler, T., Kratzsch, J., Englaro, P., Blum, W. F., Triep, K., & Kieß, W. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00761.x · Cited by 89 · see citing works

Actions of CCK in the controls of food intake and body weight: Lessons from the CCK-A receptor deficient OLETF rat

Bi, S., & Moran, T. H. (2002) · Neuropeptides · doi:10.1054/npep.2002.0895 · Cited by 88 · see citing works

A Rapid, Quantitative Immunofunctional Assay for Measuring Human Leptin

Kratzsch, J., Berthold, A., Lammert, A., Reuter, W., Keller, E., & Kieß, W. (2002) · Hormone Research in Paediatrics · doi:10.1159/000057963 · Cited by 85 · see citing works

Lactation-dependent down regulation of leptin production in mouse mammary gland

Aoki, N. (1999) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(99)00029-x · Cited by 85 · see citing works

Molecular screening of the human melanocortin-4 receptor gene: identification of a missense variant showing no association with obesity, plasma glucose, or insulin

Gotoda, T., Scott, J., & Aitman, T. J. (1997) · Diabetologia · doi:10.1007/s001250050777 · Cited by 83 · see citing works

Regulation of appetite and body weight in seasonal mammals

Mercer, J. G. (1998) · Comparative Biochemistry and Physiology Part C Pharmacology Toxicology and Endocrinology · doi:10.1016/s0742-8413(98)00018-8 · Cited by 82 · see citing works

Leptin increases energy expenditure of a marsupial by inhibition of daily torpor

Geiser, F., Körtner, G., & Schmidt, I. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.275.5.r1627 · Cited by 80 · see citing works

Serum levels of leptin, adiponectin and resistin in relation to clinical characteristics in normal pregnancy and preeclampsia

Song, Y., Gao, J., Qu, Y., Wang, S., Wang, X., & Liu, J. (2016) · Clinica Chimica Acta · doi:10.1016/j.cca.2016.04.036 · Cited by 72 · see citing works

The Effects of a High Fat Diet on Leptin mRNA, Serum Leptin and the Response to Leptin Are Not Altered in a Rat Strain Susceptible to High Fat Diet-Induced Obesity

Lin, X., Chavez, M. R., Bruch, R. C., Kilroy, G. E., Simmons, L. A., Lin, L., Braymer, H. D., Bray, G. A., & York, D. A. (1998) · Journal of Nutrition · doi:10.1093/jn/128.10.1606 · Cited by 69 · see citing works

Endotoxin-induced alteration in the expression of leptin and β3-adrenergic receptor in adipose tissue

Berkowitz, D. E., Brown, D., Lee, K. M., Emala, C. W., Palmer, D. J., An, Y., & Breslow, M. J. (1998) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1998.274.6.e992 · Cited by 66 · see citing works

Leptin as a Proinflammatory Cytokine

Lord, G. M. (2006) · KARGER eBooks · doi:10.1159/000095326 · Cited by 64 · see citing works

Effects of Long-Chain Fatty Acids on Cytosolic Triacylglycerol Accumulation and Lipid Droplet Formation in Primary Cultured Bovine Mammary Epithelial Cells

Yonezawa, T., Yonekura, S., Kobayashi, Y., Hagino, A., Katoh, K., & Obara, Y. (2004) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(04)73377-9 · Cited by 63 · see citing works

Starvation: Early Signals, Sensors, and Sequelae

Dallman, M. F. (1999) · Endocrinology · doi:10.1210/en.140.9.4015 · Cited by 62 · see citing works

Comparative digestibility and lipogenic activity in Landrace and Iberian finishing pigs fed ad libitum corn- and corn–sorghum–acorn-based diets

Morales, J., Pérez, J. F., Baucells, M. D., Mourot, J., & Gasa, J. (2002) · Livestock Production Science · doi:10.1016/s0301-6226(02)00063-5 · Cited by 61 · see citing works

The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models

Joost, H., & Schürmann, A. (2014) · Mammalian Genome · doi:10.1007/s00335-014-9514-2 · Cited by 57 · see citing works

Brain somatic cross-talk: Ghrelin, leptin and ultimate challengers of obesity

POPOVIC, V. M., & Duntas, L. H. (2005) · Nutritional Neuroscience · doi:10.1080/10284150400027107 · Cited by 55 · see citing works

Metabolic pressure and the breach of immunological self-tolerance

Rosa, V. D., Cava, A. L., & Matarese, G. (2017) · Nature Immunology · doi:10.1038/ni.3851 · Cited by 53 · see citing works

Leptin: A potential biomarker for childhood obesity?

Venner, A. A., Lyon, M. E., & Doyle–Baker, P. K. (2006) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2006.07.010 · Cited by 52 · see citing works

The Anti-Obesity Effect of Traditional Chinese Medicine on Lipid Metabolism

Fan, Q., Xu, F., Liang, B., & Zou, X. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.696603 · Cited by 52 · see citing works

Obesity and post-prandial lipid metabolism. Feast or famine?

Martins, I. J., & Redgrave, T. G. (2004) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2003.10.006 · Cited by 51 · see citing works

Leptin Gene –2548G/A variants predict risperidone-associated weight gain in children and adolescents

Calarge, C. A., Ellingrod, V. L., Zimmerman, B. M., Ación, L., Sivitz, W. I., & Schlechte, J. (2009) · Psychiatric Genetics · doi:10.1097/ypg.0b013e3283328e06 · Cited by 49 · see citing works

Mechanisms underlying the neuroendocrine response to physical exercise

Leal-Cerro, A., Gippini, A., Amaya, M. J., Lage, M., Mato, J. A., Diéguez, C., & Casanueva, F. (2003) · Journal of Endocrinological Investigation · doi:10.1007/bf03345239 · Cited by 46 · see citing works

Leptin, polycystic ovaries and polycystic ovary syndrome

Jacobs, H. S. (1999) · Human Reproduction Update · doi:10.1093/humupd/5.2.166 · Cited by 48 · see citing works

Influence of dietary fats on c-Fos-like immunoreactivity in mouse hypothalamus

Wang, H., Storlien, L. H., & Huang, X. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01927-7 · Cited by 48 · see citing works

Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians

Jenkinson, C., Cray, K., Walder, K. R., Herzog, H., Hanson, R. L., & Ravussin, É. (2000) · International Journal of Obesity · doi:10.1038/sj.ijo.0801200 · Cited by 48 · see citing works

Type 2 Diabetes Mellitus

Polonsky, K. S., & Burant, C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-29738-7.00031-9 · Cited by 50 · see citing works

Hypothalamic c-fos-like immunoreactivity in high-fat diet-induced obese and resistant mice

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