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Energy expenditure and subsequent nutrient intakes in overfed young men
Abstract
We investigated the mechanisms of body weight regulation in young men of normal body weight leading unrestricted lives. Changes in total and resting energy expenditure, body composition, and subsequent voluntary nutrient intakes in response to overeating by 4,230 +/- 115 (SE) kJ/day (1,011 +/- 27 kcal/day) for 21 days were measured in seven subjects consuming a typical diet. On average, 85-90% of the excess energy intake was deposited (with 87% of this amount in fat and 13% in protein on average). There was no detectable difference between individuals in susceptibility to energy deposition. The resting metabolic rate, averaged for fasting and fed states, increased during overfeeding (mean +/- SE, 628 +/- 197 kJ/day, P less than 0.01), but at least some of this amount was obligatory expenditure associated with nutrient assimilation. No significant increase in energy expenditure for physical activity or thermoregulation resulted from overfeeding. Thus energy expenditure did not substantially adapt to increased energy intake. However, significant decreases in voluntary energy intake (1,991 +/- 824 kJ/day, P less than 0.05) and fat intake (48 +/- 11 g/day, P less than 0.01) followed overeating, indicating that adaptive changes in nutrient intakes can contribute significantly to body weight regulation after overeating.
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“numerous well-controlled studies could not confirm mass-independent increases in REE and/or DIT during chronic overfeeding (for reviews see [9–15]).”
From Changes in energy expenditure with weight gain and weight loss in humans (2016) · cites this paper as [13]
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Self-citationThe carbohydrate-insulin model: A physiological perspective on the obesity pandemic
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Changes in energy expenditure with weight gain and weight loss in humans
Müller, M. J., Enderle, J., & Bosy-Westphal, A. (2016) · Current Obesity Reports · doi:10.1007/s13679-016-0237-4 · Cited by 267
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Effects of weight gain induced by controlled overfeeding on physical activity
Apolzan, J. W., Bray, G. A., Smith, S. R., de Jonge, L., Rood, J., Han, H., Redman, L. M., & Martin, C. K. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00386.2014 · Cited by 28
Metadata
- Authors
- Roberts, S. B., Young, V. R., Fuss, P., Fiatarone, M. A., Richard, B., Rasmussen, H., Wagner, D., Joseph, L., Holehouse, E., & Evans, W. J.
- Affiliations
- Laboratory of Human Physiology, United States Department ofAgriculture Human Nutrition Research Center on Aging at Tufts University,Boston 02111.
- Venue
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Publisher
- American Physiological Society
- Published
- 1990-09-01
- Volume
- 259
- Issue
- 3
- Pages
- R461-R469
- ISSN
- 0363-6119
- 1522-1490
- Cited by
- 13
- References
- 0
- Language
- en
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