Body temperatures during menopausal hot flashes
Abstract
Body temperatures during hot flashes were measured in a menopausal woman. Internal temperatures fell after each flash; lowest: rectal, 35.6 degrees C; vaginal, 35.6 degrees C; tympanic, 35.2 degrees C. Where sweating occurred, the skin temperature fell during the flash and rose after it. Finger and toe temperatures always showed a sharp rise at the onset of a flash with a slower fall after the flash. Only the cheeks showed additional temperature rises; maximum, 0.7 degrees C. The heart accelerated 13% at the onset of the flash but slowed immediately thereafter. The flash interval was sharply demarcated by undulations in the ECG baseline. There was never any premonitory sign of the imminence of a flash. A central excitatory state seemed to build up, perhaps by the accumulation of a chemical compound, but not of heat, which was explosively dischargedmthe thermal distress was probably evoked by vascular warming in the cheeks. Dabbing the malar prominences with cold water brought prompt relief.
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After a hot flush is triggered, the core temperature drops, as expected with activation of heat dissipation effectors.
“After a hot flush is triggered, the core temperature drops (Fig. 3) (Freedman, 2001; Kronenberg, 1990; Molnar, 1975), as expected with the activation of heat dissipation effectors.”
From Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: A novel hypothesis on the mechanism of hot flushes (2013) · cites this paper as Molnar, 1975
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Nesheim, B. I., & Saetre, T. (1982) · Maturitas · doi:10.1016/0378-5122(82)90019-6 · Cited by 12 · see citing works
Katovich, M. J., Simpkins, J. W., & O'Meara, J. (1989) · Brain Research · doi:10.1016/0006-8993(89)90146-7 · Cited by 11 · see citing works
Is calcitonin gene-related peptide a modulator of menopausal vasomotor symptoms?
de Oliveira, M. A., Lima, W. G., Schettini, D. A., Tilelli, C. Q., & Chaves, V. E. (2018) · Endocrine · doi:10.1007/s12020-018-1777-z · Cited by 11 · see citing works
Vilar-González, S., Pérez-Rozos, A., & Farpón, R. C. (2011) · Clinical & Translational Oncology · doi:10.1007/s12094-011-0633-x · Cited by 10 · see citing works
- Authors
- Molnar, G. W.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1975-03-01
- Volume
- 38
- Issue
- 3
- Pages
- 499-503
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2257282484
- Cited by
- 156
- References
- 0
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 3 · 2023: 2 · 2022: 1 · 2021: 3 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 2 · 2015: 2 · 2014: 4 · 2013: 2 · 2012: 2
- FWCI
- 1.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Thermal Regulation in Medicine
- Keywords
- menopausal hot flashes, body temperature, rectal temperature, vaginal temperature, tympanic temperature, skin temperature, heart rate, sweating, menopause
- MeSH terms
- Body Temperature, Cheek, Electrocardiography, Female, Heart Rate, Humans, Menopause, Middle Aged, Skin Temperature, Time Factors
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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