LH, FSH AND SKIN TEMPERATURE DURING THE MENOPAUSAL HOT FLAS
Abstract
Six postmenopausal women, who were experiencing frequent hot flashes, had an 8 h continuous recording of skin temperature over the dorsum of the finger as an objective index of hot flashes. Frequent blood samples were obtained during the time of the recording for the measurement of serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels. During the 48 h of recording 34 significant temperature elevations were recorded and 32 were associated with a subjective hot flash. 3l pulses of LH release were also observed with 26 occurring simultaneously with the temperature rises. Correlation analysis of simultaneous skin temperature and circulating LH levels showed a significant positive correlation (p less than 0.01). FSH levels showed no consistent relationship with skin temperature. These data suggest that LH or the factors that trigger its pulsatile release are related to the mechanism responsible for the initiation of hot flashes.
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Blood sampling at frequent intervals has revealed synchronization of LH pulses and hot flushes.
“Blood sampling at frequent intervals have revealed synchronization of LH pulses and hot flushes (Casper et al., 1979; Tataryn et al., 1979).”
From Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: A novel hypothesis on the mechanism of hot flushes (2013) · cites this paper as Tataryn et al., 1979
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- Authors
- Tataryn, I. V., Meldrum, D. R., Lu, K. H., Fruraar, A. M., & Judd, H. L.
- Affiliations
- University of California, Los Angeles (US)
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 1979-07
- Volume
- 49
- Issue
- 1
- Pages
- 152-154
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2167000872
- Cited by
- 200
- References
- 20
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 4 · 2016: 2 · 2015: 4 · 2014: 4 · 2013: 4 · 2012: 1
- FWCI
- 6.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Keywords
- menopausal hot flashes, luteinizing hormone, follicle-stimulating hormone, skin temperature, postmenopausal women
- MeSH terms
- Climacteric, Female, Follicle Stimulating Hormone, Humans, Luteinizing Hormone, Skin Temperature, Time Factors
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