Contraction-activated glucose uptake is normal in insulin-resistant muscle of the obese Zucker rat
Abstract
The rates of muscle glucose uptake of lean and obese Zucker rats were assessed via hindlimb perfusion under basal conditions (no insulin), in the presence of a maximal insulin concentration (10 mU/ml), and after electrically stimulated muscle contraction in the absence of insulin. The perfusate contained 28 mM glucose and 7.5 microCi/mmol of 2-deoxy-D-[3H-(G)]glucose. Glucose uptake rates in the soleus (slow-twitch oxidative fibers), red gastrocnemius (fast-twitch oxidative-glycolytic fibers), and white gastrocnemius (fast-twitch glycolytic fibers) under basal conditions and after electrically stimulated muscle contraction were not significantly different between the lean and obese rats. However, the rate of glucose uptake during insulin stimulation was significantly lower for obese than for lean rats in all three fiber types. Significant correlations were found for insulin-stimulated glucose uptake and glucose transporter protein isoform (GLUT-4) content of soleus, red gastrocnemius, and white gastrocnemius of lean (r = 0.79) and obese (r = 0.65) rats. In contrast, the relationships between contraction-stimulated glucose uptake and muscle GLUT-4 content of lean and obese rats were negligible because of inordinately low contraction-stimulated glucose uptakes by the solei. These results suggest that maximal skeletal muscle glucose uptake of obese Zucker rats is resistant to stimulation by insulin but not to contractile activity. In addition, the relationship between contraction-stimulated glucose uptake and GLUT-4 content appears to be fiber-type specific.
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Contraction-mediated glucose uptake is maintained in humans and diet and genetic rodent models of insulin resistance.
“4) Contraction-mediated glucose uptake is maintained in humans and diet and genetic rodent models of insulin resistance [111-114].”
From AMPK and Exercise: Glucose Uptake and Insulin Sensitivity (2013) · cites this paper as [114]
Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works
Morgan, C. R., & Lazarow, A. (1963) · Diabetes · doi:10.2337/diab.12.2.115 · Cited by 2,197 · see citing works
HINDLIMB MUSCLE FIBER POPULATIONS OF FIVE MAMMALS
Ariano, M. A., Edgerton, V. R., & Armstrong, R. B. (1973) · Journal of Histochemistry & Cytochemistry · doi:10.1177/21.1.51 · Cited by 1,118 · see citing works
Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein
James, D. E., Brown, R., Navarro, J., & Pilch, P. F. (1988) · Nature · doi:10.1038/333183a0 · Cited by 666 · see citing works
Muscle Glucose Metabolism following Exercise in the Rat
Richter, E. A., Garetto, L. P., Goodman, M. N., & Ruderman, N. B. (1982) · Journal of Clinical Investigation · doi:10.1172/jci110517 · Cited by 510 · see citing works
Evaluation of the isolated perfused rat hindquarter for the study of muscle metabolism
Ruderman, N. B., Houghton, C. R. S., & Hems, R. (1971) · Biochemical Journal · doi:10.1042/bj1240639 · Cited by 446 · see citing works
Glucose transporter protein content and glucose transport capacity in rat skeletal muscles
Henriksen, E. J., Bourey, R. E., Rodnick, K. J., Koranyi, L. I., Permutt, M. A., & Holloszy, J. O. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.4.e593 · Cited by 435 · see citing works
Insulin responsiveness in skeletal muscle is determined by glucose transporter (Glut4) protein level
Kern, M., Wells, J. A., Stephens, J. M., Elton, C. W., Friedman, J. E., Tapscott, E. B., Pekala, P. H., & Dohm, G. L. (1990) · Biochemical Journal · doi:10.1042/bj2700397 · Cited by 268 · see citing works
Dissociation of effects of insulin and contraction on glucose transport in rat epitrochlearis muscle
Нешер, Р., Karl, I. E., & KIPNIS, D. M. (1985) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1985.249.3.c226 · Cited by 255 · see citing works
Hirshman, M. F., Goodyear, L. J., Wardzala, L. J., Horton, E. D., & Horton, E. S. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40147-6 · Cited by 243 · see citing works
Persistent increase in glucose uptake by rat skeletal muscle following exercise
Ivy, J. L., & Holloszy, J. O. (1981) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1981.241.5.c200 · Cited by 185 · see citing works
Self-citationActivation of glucose transport in diabetic muscle: responses to contraction and insulin
Wallberg‐Henriksson, H., & Holloszy, J. O. (1985) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1985.249.3.c233 · Cited by 148 · see citing works
Recruitment of GLUT-4 glucose transporters by insulin in diabetic rat skeletal muscle
Klip, A., Ramlal, T., Bilan, P. J., Cartee, G. D., Gulve, E. A., & Holloszy, J. O. (1990) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(90)90735-6 · Cited by 142 · see citing works
Exercise-Induced Increase in Glucose Transporters in Plasma Membranes of Rat Skeletal Muscle*
Douen, A. G., Ramlal, T., Klip, A., YOUNG, D. A., Cartee, G. D., & Holloszy, J. O. (1989) · Endocrinology · doi:10.1210/endo-124-1-449 · Cited by 135 · see citing works
Rate-limiting steps for insulin-mediated glucose uptake into perfused rat hindlimb.
Kubo, K., & Foley, J. (1986) · American Journal of Physiology · doi:10.1152/ajpendo.1986.250.1.e100 · Cited by 132 · see citing works
Effect of denervation or unweighting on GLUT-4 protein in rat soleus muscle
Henriksen, E. J., Rodnick, K. J., Mondon, C. E., James, D. E., & Holloszy, J. O. (1991) · Journal of Applied Physiology · doi:10.1152/jappl.1991.70.5.2322 · Cited by 117 · see citing works
Acute exercise increases the number of plasma membrane glucose transporters in rat skeletal muscle
Hirshman, M. F., Wallberg‐Henriksson, H., Wardzala, L. J., Horton, E. D., & Horton, E. S. (1988) · FEBS Letters · doi:10.1016/0014-5793(88)80486-1 · Cited by 113 · see citing works
Exercise modulates the insulin‐induced translocation of glucose transporters in rat skeletal muscle
Douen, A. G., Ramlal, T., Cartee, G. D., & Klip, A. (1990) · FEBS Letters · doi:10.1016/0014-5793(90)80566-2 · Cited by 84 · see citing works
Insulin response in skeletal muscle and fat cells of the genetically obese Zucker rat
Czech, M., Richardson, D. K., Becker, S. G., Walters, C. G., Gitomer, W., & Heinrich, J. N. (1978) · Metabolism · doi:10.1016/s0026-0495(78)80013-4 · Cited by 81 · see citing works
Strout, H. V., Vicario, P. P., Biswas, C., Saperstein, R., Brady, E. J., Pilch, P. F., & Berger, J. (1990) · Endocrinology · doi:10.1210/endo-126-5-2728 · Cited by 76 · see citing works
Glucose transport: locus of muscle insulin resistance in obese Zucker rats
Sherman, W. M., Katz, A. L., Cutler, C. L., Withers, R. T., & Ivy, J. L. (1988) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1988.255.3.e374 · Cited by 69 · see citing works
Self-citationSkeletal muscle glucose transport in obese Zucker rats after exercise training
Ivy, J. L., Brozinick, J. T., TORGAN, C. E., & Kastello, G. M. (1989) · Journal of Applied Physiology · doi:10.1152/jappl.1989.66.6.2635 · Cited by 67 · see citing works
Self-citationPostreceptor defect in insulin action in streptozotocin-induced diabetic rats
Nishimura, H., Kuzuya, H., Okamoto, M., Yamada, K. D., Kosaki, A., Kakehi, T., Inoue, G., Kono, S., & Imura, H. (1989) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1989.256.5.e624 · Cited by 35 · see citing works
Exercise and diet reduce muscle insulin resistance in obese Zucker rat
Ivy, J. L., Sherman, W. M., Cutler, C. L., & Katz, A. L. (1986) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1986.251.3.e299 · Cited by 30 · see citing works
Self-citationMuscle glucose uptake of obese Zucker rats trained at two different intensities
Willems, M. E. T., Brozinick, J. T., TORGAN, C. E., Cortez, M. Y., & Ivy, J. L. (1991) · Journal of Applied Physiology · doi:10.1152/jappl.1991.70.1.36 · Cited by 20 · see citing works
Self-citationSubstrate utilization during acute exercise in obese Zucker rats
TORGAN, C. E., Brozinick, J. T., Willems, M. E. T., & Ivy, J. L. (1990) · Journal of Applied Physiology · doi:10.1152/jappl.1990.69.6.1987 · Cited by 15 · see citing works
Self-citationEffect of prior immobilization on muscular glucose clearance in resting and running rats
Vissing, J., Ohkuwa, T., Ploug, T., & Galbo, H. (1988) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1988.255.4.e456 · Cited by 10 · see citing works
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Exercise, Glucose Transport, and Insulin Sensitivity
Goodyear, L. J., & Kahn, B. B. (1998) · Annual Review of Medicine · doi:10.1146/annurev.med.49.1.235 · Cited by 1,056 · see citing works
Glatz, J. F. C., Luiken, J. J. F. P., & Bonen, A. (2010) · Physiological Reviews · doi:10.1152/physrev.00003.2009 · Cited by 757 · see citing works
Intensity and Amount of Physical Activity in Relation to Insulin Sensitivity
Mayer-Davis, E. J. (1998) · JAMA · doi:10.1001/jama.279.9.669 · Cited by 598 · see citing works
Invited Review: Effects of acute exercise and exercise training on insulin resistance
Henriksen, E. J. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01219.2001 · Cited by 535 · see citing works
Exercise regulation of glucose transport in skeletal muscle.
Hayashi, T., Wojtaszewski, J., & Goodyear, L. (1997) · American Journal of Physiology · doi:10.1152/ajpendo.1997.273.6.e1039 · Cited by 394 · see citing works
Musi, N., Fujii, N., Hirshman, M. F., Ekberg, I., Fröberg, S., Ljungqvist, O., Thorell, A., & Goodyear, L. J. (2001) · Diabetes · doi:10.2337/diabetes.50.5.921 · Cited by 371 · see citing works
Effect of AMPK activation on muscle glucose metabolism in conscious rats
Bergeron, R., Russell, R. R., Young, L. H., Ren, J., Marcucci, M., Lee, A., & Shulman, G. I. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.276.5.e938 · Cited by 301 · see citing works
HUGHES, V. A., FIATARONE, M. A., Fielding, R. A., Kahn, B. B., Ferrara, C. M., Shepherd, P. R., Fisher, E. C., Wolfe, R. R., Elahi, D., & Evans, W. J. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.264.6.e855 · Cited by 300 · see citing works
AMPK and Exercise: Glucose Uptake and Insulin Sensitivity
O'Neill, H. M. (2013) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2013.37.1.1 · Cited by 295 · see citing works
Bergeron, R., Previs, S. F., Cline, G. W., Perret, P., Russell, R. R., Young, L. H., & Shulman, G. I. (2001) · Diabetes · doi:10.2337/diabetes.50.5.1076 · Cited by 280 · see citing works
Lee, A. D., Hansen, P. A., & Holloszy, J. O. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00147-2 · Cited by 234 · see citing works
Harfmann, B. D., Schroder, E. A., Kachman, M. T., Hodge, B. A., Zhang, X., & Esser, K. A. (2016) · Skeletal Muscle · doi:10.1186/s13395-016-0082-x · Cited by 231 · see citing works
Exercise-stimulated glucose transport in skeletal muscle is nitric oxide dependent
Roberts, C. K., Barnard, R. J., Scheck, S. H., & Balon, T. W. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.1.e220 · Cited by 208 · see citing works
Coderre, L., Kandror, K. V., Vallega, G., & Pilch, P. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.46.27584 · Cited by 195 · see citing works
Kang, J., Robertson, R. J., Hagberg, J. M., Kelley, D. E., Goss, F. L., DaSilva, S. G., Suminski, R. R., Jr., & Utter, A. C. (1996) · Diabetes Care · doi:10.2337/diacare.19.4.341 · Cited by 177 · see citing works
Regulation of glucose transport into skeletal muscle
Holloszy, J. O., & Hansen, P. A. (1996) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/3-540-61343-9_8 · Cited by 151 · see citing works
AMP‐activated protein kinase and muscle glucose uptake
Musi, N., & Goodyear, L. J. (2003) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01168.x · Cited by 145 · see citing works
Effects of captopril on glucose transport activity in skeletal muscle of obese Zucker rats
Henriksen, E. J., & Jacob, S. (1995) · Metabolism · doi:10.1016/0026-0495(95)90276-7 · Cited by 137 · see citing works
Regulation of GLUT4 protein and glycogen synthase during muscle glycogen synthesis after exercise
IVY, J. L., & KUO, C. ‐. (1998) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.1998.0302e.x · Cited by 129 · see citing works
Self-citationEffect of tension on contraction-induced glucose transport in rat skeletal muscle
Ihlemann, J., Ploug, T., Hellsten, Y., & Galbo, H. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.2.e208 · Cited by 122 · see citing works
Carbohydrate ingestion and glycogen utilization in different muscle fibre types in man
Tsintzas, O. K., Williams, C., Boobis, L., & Greenhaff, P. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp021046 · Cited by 117 · see citing works
Effects of exercise training on muscle GLUT-4 protein content and translocation in obese Zucker rats
Brozinick, J. T., Etgen, G. J., Yaspelkis, B. B., Kang, H. Y., & Ivy, J. L. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.3.e419 · Cited by 113 · see citing works
Self-citationHolloway, G. P., Benton, C. R., Mullen, K. L., Yoshida, Y., Snook, L. A., Han, X.-X., Glatz, J. F. C., Luiken, J. J. F. P., Lally, J., Dyck, D. J., et al. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90896.2008 · Cited by 107 · see citing works
LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats and effects of training
Sriwijitkamol, A., Ivy, J. L., Christ-Roberts, C. Y., DeFronzo, R. A., Mandarino, L. J., & Musi, N. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00429.2005 · Cited by 103 · see citing works
Self-citationGlucose transport and cell surface GLUT-4 protein in skeletal muscle of the obese Zucker rat
Etgen, G. J., Wilson, C. M., Jensen, J., Cushman, S. W., & Ivy, J. L. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.271.2.e294 · Cited by 100 · see citing works
Self-citationEtgen, G. J., Jensen, J., Wilson, C. M., Hunt, D. G., Cushman, S. W., & Ivy, J. L. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.5.e864 · Cited by 88 · see citing works
Self-citationMuscle glucose transport, GLUT-4 content, and degree of exercise training in obese Zucker rats
Banks, E. A., Brozinick, J. T., Yaspelkis, B. B., Kang, H. Y., & Ivy, J. L. (1992) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1992.263.5.e1015 · Cited by 88 · see citing works
Self-citationExercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat.
Hevener, A. L., Reichart, D. R., & Olefsky, J. M. (2000) · Diabetes · doi:10.2337/diabetes.49.12.2154 · Cited by 86 · see citing works
Colberg, S. R., Hagberg, J. M., McCole, S. D., Zmuda, J. M., Thompson, P. D., & Kelley, D. E. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.5.2027 · Cited by 85 · see citing works
Tanaka, S., Hayashi, T., Toyoda, T., Hamada, T., Shimizu, Y., Hirata, M., Ebihara, K., Masuzaki, H., Hosoda, K., Fushiki, T., et al. (2007) · Metabolism · doi:10.1016/j.metabol.2007.07.017 · Cited by 82 · see citing works
Han, X.-X., Chabowski, A., Tandon, N. N., Calles-Escandón, J., Glatz, J. F. C., Luiken, J. J. F. P., & Bonen, A. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00106.2007 · Cited by 78 · see citing works
Muscle insulin resistance amended with exercise training: role of GLUT4 expression.
Ivy, J. L. (2004) · PubMed · Cited by 74 · see citing works
Self-citationGLUT4 Overexpression in db/db Mice Dose-Dependently Ameliorates Diabetes But Is Not a Lifelong Cure
Brozinick, J. T., McCoid, S. C., Reynolds, T., Nardone, N. A., Hargrove, D. M., Stevenson, R. W., Cushman, S. W., & Gibbs, E. M. (2001) · Diabetes · doi:10.2337/diabetes.50.3.593 · Cited by 76 · see citing works
Self-citationKang, J., Kelley, D. E., Robertson, R. J., Goss, F. L., Suminski, R. R., Jr., UTTER, A. C., & DaSilva, S. G. (1999) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199901000-00014 · Cited by 70 · see citing works
Wheatley, C., Rattigan, S., Richards, S. M., Barrett, E. J., & Clark, M. G. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00077.2004 · Cited by 61 · see citing works
Glucose uptake and GLUT-4 protein distribution in skeletal muscle of the obese Zucker rat
Brozinick, J. T., Etgen, G. J., Yaspelkis, B. B., & Ivy, J. L. (1994) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1994.267.1.r236 · Cited by 60 · see citing works
Self-citationPark, D., Park, K., Kim, B., Yoon, C.-S., & Kim, U. (2014) · Diabetes · doi:10.2337/db14-0939 · Cited by 58 · see citing works
Exercise and Diet in the Prevention and Control of the Metabolic Syndrome
Barnard, R. J., & Wen, S. J. (1994) · Sports Medicine · doi:10.2165/00007256-199418040-00002 · Cited by 58 · see citing works
Cachectic skeletal muscle response to a novel bout of low-frequency stimulation
Puppa, M., Murphy, E. A., Fayad, R., Hand, G. A., & Carson, J. A. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01270.2013 · Cited by 52 · see citing works
An Overview of Muscle Glucose Uptake during Exercise
Wasserman, D. H., & Halseth, A. E. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4899-1928-1_1 · Cited by 51 · see citing works
Polonsky, K. S., & Burant, C. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-29738-7.00031-9 · Cited by 50 · see citing works
Nakanishi, N., Takatorige, T., & Suzuki, K. (2004) · Diabetologia · doi:10.1007/s00125-004-1528-y · Cited by 44 · see citing works
Galbo, H., Tobin, L., & van Loon, L. J. C. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-029 · Cited by 44 · see citing works
Roy, D., Jóhannsson, E., Bonen, A., & Marette, A. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.4.e688 · Cited by 44 · see citing works
Etgen, G. J., Memon, A. R., Thompson, G. A., & Ivy, J. L. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)80708-x · Cited by 44 · see citing works
Self-citationReynolds, T., Brozinick, J. T., Rogers, M. A., & Cushman, S. W. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.2.e320 · Cited by 40 · see citing works
Self-citationGnudi, L., Shepherd, P. R., & Kahn, B. B. (1996) · Proceedings of The Nutrition Society · doi:10.1079/pns19960020 · Cited by 37 · see citing works
Ruzzin, J., & Jensen, J. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00587.2004 · Cited by 33 · see citing works
Buse, J. B., Polonsky, K. S., & Burant, C. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-0324-5.00031-6 · Cited by 28 · see citing works
Regulation of cell surface GLUT4 in skeletal muscle of transgenic mice
Brozinick, J. T., McCoid, S. C., REYNOLDS, T. H., Wilson, C. M., Stevenson, R. W., Cushman, S. W., & GIBBS, E. M. (1997) · Biochemical Journal · doi:10.1042/bj3210075 · Cited by 27 · see citing works
Self-citationPloug, T., Ohkuwa, T., Handberg, A., Vissing, J., & Galbo, H. (1995) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1995.268.5.e980 · Cited by 27 · see citing works
Richter, E. A. (1996) · Comprehensive physiology · doi:10.1002/cphy.cp120120 · Cited by 25 · see citing works
Postexercise muscle glycogen resynthesis in obese insulin-resistant Zucker rats
Bruce, C. R., Lee, J. S., & Hawley, J. A. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.4.1512 · Cited by 22 · see citing works
Contraction-mediated glucose uptake is increased in men with impaired glucose tolerance
Skov-Jensen, C., Skovbro, M., Flint, A., Helge, J. W., & Dela, F. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h06-098 · Cited by 21 · see citing works
Regulation of Muscle Glucose Uptake In Vivo
Mandarino, L. J., Bonadonna, R. C., McGuinness, O. P., Halseth, A. E., & Wasserman, D. H. (2001) · Comprehensive physiology · doi:10.1002/cphy.cp070227 · Cited by 19 · see citing works
Exercise and Mitochondrial Remodeling in Skeletal Muscle in Type 2 Diabetes
Lee, H., & Song, W. J. (2018) · Journal of Obesity & Metabolic Syndrome · doi:10.7570/jomes.2018.27.3.150 · Cited by 19 · see citing works
Bonen, A. (1995) · Canadian Journal of Applied Physiology · doi:10.1139/h95-020 · Cited by 19 · see citing works
Anatomy of Glucose Transporters in Skeletal Muscle
Ploug, T., & Ralston, E. (1998) · Advances in experimental medicine and biology · doi:10.1007/978-1-4899-1928-1_2 · Cited by 18 · see citing works
Jain, S., Snook, L. A., Glatz, J. F. C., Luiken, J. J. F. P., Holloway, G. P., Thurmond, D. C., & Bonen, A. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.05.061 · Cited by 15 · see citing works
Hong, Y. H., Betik, A. C., Premilovac, D., Dwyer, R. M., Keske, M. A., Rattigan, S., & McConell, G. K. (2015) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00412.2014 · Cited by 15 · see citing works
Wadley, G. D., Bruce, C. R., Konstantopoulos, N., Macaulay, S. L., Howlett, K. F., Hawley, J. A., & Cameron‐Smith, D. (2004) · Diabetologia · doi:10.1007/s00125-003-1322-2 · Cited by 12 · see citing works
The effect of acute exercise on glycogen synthesis rate in obese subjects studied by 13C MRS
van der Graaf, M., de Haan, J. H., Smits, P., Mulder, A. H., Heerschap, A., & Tack, C. J. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1650-0 · Cited by 11 · see citing works
Therapeutic Effects of Lipoic Acid on Hyperglycemia and Insulin Resistance
Henriksen, E. (2001) · CRC Press eBooks · doi:10.1201/9780203904046.ch26 · Cited by 8 · see citing works
Mokhtarian, A., & Even, P. C. (1996) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s004240050148 · Cited by 7 · see citing works
Pharmacodynamic characterization of insulin on MDMA-induced thermogenesis
Banks, M. L., Buzard, S. K., Gehret, C. M., Monroy, A. N., Kenaston, M. A., Mills, E., & Sprague, J. E. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.05.021 · Cited by 6 · see citing works
Culprits or consequences: Understanding the metabolic dysregulation of muscle in diabetes
O’Reilly, C. L., Uranga, S., & Fluckey, J. D. (2021) · World Journal of Biological Chemistry · doi:10.4331/wjbc.v12.i5.70 · Cited by 5 · see citing works
Wu, M.-C., Tsai, Y., Huang, C., Kao, C., Hou, C., Chen, C., Korivi, M., Jean, W., Lee, S., & Kuo, C. (2011) · European Journal of Sport Science · doi:10.1080/17461391.2011.606839 · Cited by 5 · see citing works
Klip, A., & Marette, A. (2001) · Comprehensive physiology · doi:10.1002/cphy.cp070214 · Cited by 5 · see citing works
Solis, R. M. S., Kim, J., & Cartee, G. D. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00953.2004 · Cited by 4 · see citing works
Interaction between Lipid Availability, Endurance Exercise and Insulin Sensitivity
Newsom, S. A., & Schenk, S. (2014) · Medicine and sport science/Medicine and sport · doi:10.1159/000357336 · Cited by 3 · see citing works
Carson, J. A., & Puppa, M. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4493-0_5 · Cited by 2 · see citing works
Metabolic Alterations in Muscle Associated with Obesity
Thyfault, J. P., & Dohm, G. L. (2005) · CRC Press eBooks · doi:10.1201/9781420038798-6 · Cited by 1 · see citing works
Insulin Resistance, Diabetes and its Complications
Ng, D. S. (2006) · Wiley-VCH eBooks · doi:10.1002/3527600906.mcb.200400011
Physical activity and diabetic complications in patients with type 1 diabetes
Wadén, J. (2010) · Työväentutkimus Vuosikirja
Puppa, M. (2014) · Scholar Commons (University of South Carolina)
Regulation of Insulin Signalling by Exercise in Skeletal Muscle
Wadley, G. D. (2003) · Figshare
Lee, J. S., Hawley, J. A., Melanson, E. L., Wyatt, H. R., Eckel, R. H., Hill, J. O., Steig, J., Jackman, M. R., Giles, E. D., HIGGINS, J. A., et al. (2015)
Self-citationHarfmann, B. D. (2015) · UKnowledge (University of Kentucky)
Loyd, C. (2014) · OhioLink ETD Center (Ohio Library and Information Network)
Galbo, H., & Richter, E. A. (2015) · Wiley eBooks · doi:10.1002/9781118387658.ch41
Galbo, H., & Richter, E. A. (2004) · Wiley eBooks · doi:10.1002/0470862092.d0607
Burant, C. (2000) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-59651-3_15
Metabolic Alterations in Muscle Associated with Obesity
Thyfault, J. P., & Dohm, G. L. (2005) · CRC Press eBooks · doi:10.1201/9781420038798.ch5
Richter, E. A. (1995) · Comprehensive physiology · doi:10.1002/j.2040-4603.1995.tb01717.x
Regulation of Muscle Glucose Uptake In Vivo
Mandarino, L. J., Bonadonna, R. C., McGuinness, O. P., Halseth, A. E., & Wasserman, D. H. (2001) · Comprehensive physiology · doi:10.1002/j.2040-4603.2001.tb01473.x
Tsintzas, O. K. (1993) · doi:10.12681/eadd/4687 · Cited by 2 · see citing works
- Authors
- Brozinick, J. T., Etgen, G. J., Yaspelkis, B. B., & Ivy, J. L.
- Affiliations
- The University of Texas at Austin (US)
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1992-07-01
- Volume
- 73
- Issue
- 1
- Pages
- 382-387
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2315090378
- Cited by
- 89
- References
- 27
- Citations by year
- 2021: 2 · 2018: 1 · 2016: 2 · 2015: 4 · 2014: 5 · 2013: 1 · 2012: 2
- FWCI
- 1.83
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Keywords
- skeletal muscle glucose uptake, insulin resistance, muscle contraction, GLUT4, skeletal muscle fiber types, soleus muscle, gastrocnemius, obesity, Zucker rats, hindlimb perfusion, 2-deoxyglucose
- MeSH terms
- Animals, Deoxyglucose, Electric Stimulation, Female, Glucose, Insulin Resistance, Isomerism, Monosaccharide Transport Proteins, Muscle Contraction, Muscles, Obesity, Rats, Zucker, Rats
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