Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase
Open accessAbstract
Previous studies have demonstrated that oxygen consumption and fat oxidation remain elevated in the postexercise period. The purpose of this study was to determine whether malonyl-CoA, an inhibitor of fatty acid oxidation, remains depressed in muscle after exercise. Rats were sprinted for 5 min (40 m/min, 5% grade) or run for 30 min (21 m/min, 15% grade). Red quadriceps malonyl-CoA returned to resting values by 90 min postexercise in the sprinting rats and remained significantly lower at least 90 min postexercise in the 30-min exercise group. AMP-activated protein kinase activity remained significantly elevated ( P < 0.05) for 10 min after exercise in both groups. The most rapid rate of glycogen repletion was in the first 30 min postexercise. The respiratory exchange ratio decreased from a nonexercise value of 0.87 ± 0.01 to an average 0.82 ± 0.01 during the 90-min period after 30 min of exercise. Thus muscle malonyl-CoA remains depressed and fat oxidation is elevated for relatively prolonged periods after a single bout of exercise. This may allow fat oxidation to contribute more to muscle energy requirements, thus leaving more glucose for replenishment of muscle glycogen.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
AMPK is activated during exercise in both rodents and humans.
“Consistent with this, AMPK is activated during exercise in both rodents and humans [51-60], in an intensity-dependent manner [57,59-61].”
From AMPK and Exercise: Glucose Uptake and Insulin Sensitivity (2013) · cites this paper as [54]
Cites
Plum, F. (1960) · Archives of Neurology · doi:10.1001/archneur.1960.03840090124020 · Cited by 10,388 · see citing works
Romijn, J. A., Coyle, E. F., Sidossis, L. S., Gastaldelli, A., Horowitz, J. F., Endert, E., & Wolfe, R. R. (1993) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1993.265.3.e380 · Cited by 1,747 · see citing works
The Mitochondrial Carnitine Palmitoyltransferase System — From Concept to Molecular Analysis
McGarry, J. D., & Brown, N. F. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00001.x · Cited by 1,616 · cited 2× · see citing works
“This is in agreement with previous studies on liver and heart that have shown an inverse correlation of malonyl-CoA content and fatty acid oxidation rate (1, 15, 23).”
BackgroundResultThe AMP‐Activated Protein Kinase: Fuel Gauge of the Mammalian Cell?
Hardie, D. G., & Carling, D. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00259.x · Cited by 1,317 · see citing works
Exercise, Glucose Transport, and Insulin Sensitivity
Goodyear, L. J., & Kahn, B. B. (1998) · Annual Review of Medicine · doi:10.1146/annurev.med.49.1.235 · Cited by 1,056 · see citing works
Merrill, G. F., Kurth, E. J., Hardie, D. G., & Winder, W. W. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.6.e1107 · Cited by 1,027 · see citing works
Self-citationSlein, M. W. (1965) · Elsevier eBooks · doi:10.1016/b978-0-12-395630-9.50023-2 · Cited by 850 · see citing works
Exercise : regulation and integration of multiple systems
Rowell, L. B., & Shepherd, J. T. (1996) · Medical Entomology and Zoology · Cited by 810 · see citing works
Winder, W. W., & Hardie, D. G. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.2.e299 · Cited by 799 · see citing works
Self-citation[7] Chemical procedures for analysis of polysaccharides
Hassid, W. Z., & Abraham, S. (1957) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(57)03345-5 · Cited by 712 · see citing works
Colorimetric ultramicro method for the determination of free fatty acids
Novák, M. (1965) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39315-9 · Cited by 639 · see citing works
DAVIES, S. P., Carling, D., & Hardie, D. G. (1989) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1989.tb15185.x · Cited by 431 · see citing works
Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle
Vavvas, D., Apazidis, A., Saha, A. K., Gamble, J., Patel, A., Kemp, B. E., Witters, L. A., & Ruderman, N. B. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.20.13255 · Cited by 395 · see citing works
Exercise regulation of glucose transport in skeletal muscle.
Hayashi, T., Wojtaszewski, J., & Goodyear, L. (1997) · American Journal of Physiology · doi:10.1152/ajpendo.1997.273.6.e1039 · Cited by 394 · see citing works
Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart.
Saddik, M., Gamble, J., Witters, L. A., & Lopaschuk, G. D. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74465-2 · Cited by 390 · see citing works
Wolfe, R. R., Klein, S., Carraro, F., & Weber, J. M. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.258.2.e382 · Cited by 381 · see citing works
Adaptation of muscle to exercise
Molé, P. A., Oscai, L. B., & Holloszy, J. O. (1971) · Journal of Clinical Investigation · doi:10.1172/jci106730 · Cited by 320 · see citing works
Hutber, C. A., Hardie, D. G., & Winder, W. W. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.2.e262 · Cited by 229 · see citing works
Self-citationMalonyl-CoA metabolism in cardiac myocytes and its relevance to the control of fatty acid oxidation
Awan, M. M., & SAGGERSON, E. D. (1993) · Biochemical Journal · doi:10.1042/bj2950061 · Cited by 196 · see citing works
McGarry, J., Stark, M. J., & Foster, D. W. (1978) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)34394-6 · Cited by 188 · see citing works
End points of lactate and glucose metabolism after exhausting exercise
Brooks, G. A., & Gaesser, G. A. (1980) · Journal of Applied Physiology · doi:10.1152/jappl.1980.49.6.1057 · Cited by 167 · see citing works
Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase
Rasmussen, B. B., & Winder, W. W. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.83.4.1104 · Cited by 158 · see citing works
Self-citationRegulation of glucose transport into skeletal muscle
Holloszy, J. O., & Hansen, P. A. (1996) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/3-540-61343-9_8 · Cited by 151 · see citing works
Regulation of Carbohydrate and Fat Metabolism During and After Exercise
Holloszy, J. O., & Kohrt, W. M. (1996) · Annual Review of Nutrition · doi:10.1146/annurev.nu.16.070196.001005 · Cited by 129 · see citing works
Vusse, G. J., & Reneman, R. S. (1996) · Comprehensive physiology · doi:10.1002/cphy.cp120121 · Cited by 128 · see citing works
Malonyl-CoA regulation in skeletal muscle: its link to cell citrate and the glucose-fatty acid cycle
Saha, A. K., Vavvas, D. G., Kurowski, T. G., Apazidis, A., Witters, L. A., Shafrir, E., & Ruderman, N. B. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.272.4.e641 · Cited by 124 · see citing works
Human skeletal muscle malonyl-CoA at rest and during prolonged submaximal exercise
Odland, L. M., Heigenhauser, G. J. F., Lopaschuk, G. D., & Spriet, L. L. (1996) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1996.270.3.e541 · Cited by 112 · see citing works
Effects of exercise intensity on 24-h energy expenditure and substrate oxidation
Treuth, M. S., Hunter, G. R., & WILLIAMS, M. (1996) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199609000-00009 · Cited by 90 · see citing works
Time course of exercise-induced decline in malonyl-CoA in different muscle types
Winder, W. W., AROGYASAMI, J., Elayan, I., & Cartmill, D. C. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.2.e266 · Cited by 83 · see citing works
Self-citation5 Malonyl-CoA???Regulator of Fatty Acid Oxidation in Muscle During Exercise
Winder, W. W. (1998) · Exercise and Sport Sciences Reviews · doi:10.1249/00003677-199800260-00007 · Cited by 51 · see citing works
Self-citationAttenuation of postexercise ketosis in fasted endurance-trained rats
Beattie, M. A., & Winder, W. W. (1985) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1985.248.1.r63 · Cited by 15 · see citing works
Self-citationImpaired plasma FFA oxidation imposed by extreme CHO deficiency in contracting rat skeletal muscle
Turcotte, L. P., Hespel, P., Graham, T. E., & Richter, E. A. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.77.2.517 · Cited by 14 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
AMP-activated protein kinase, a metabolic master switch: possible roles in Type 2 diabetes
Winder, W. W., & Hardie, D. G. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.1.e1 · Cited by 1,000 · see citing works
Self-citationTomas, E., Tsao, T.-S., Saha, A. K., Murrey, H. E., Zhang, C. C., Itani, S. I., Lodish, H. F., & Ruderman, N. B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.222657499 · Cited by 973 · see citing works
Musi, N., Hirshman, M. F., Nygren, J., Svanfeldt, M., Bavenholm, P., Rooyackers, O., Zhou, G., Williamson, J. M., Ljunqvist, O., Efendic, S., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2074 · Cited by 806 · see citing works
Dreyer, H. C., Fujita, S., Cadenas, J. G., Chinkes, D. L., Volpi, E., & Rasmussen, B. B. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.113175 · Cited by 570 · see citing works
Self-citationAMPK in skeletal muscle function and metabolism
Kjøbsted, R., Hingst, J. R., Fentz, J., Foretz, M., Sanz, M.-N., Pehmøller, C. K., Shum, M., Marette, A., Mounier, R., Treebak, J. T., et al. (2017) · The FASEB Journal · doi:10.1096/fj.201700442r · Cited by 496 · see citing works
Wojtaszewski, J. F. P., Nielsen, P., Hansen, B. F., Richter, E. A., & Kiens, B. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00221.x · Cited by 435 · see citing works
Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle
Winder, W. W. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.3.1017 · Cited by 375 · see citing works
Self-citationMusi, N., Fujii, N., Hirshman, M. F., Ekberg, I., Fröberg, S., Ljungqvist, O., Thorell, A., & Goodyear, L. J. (2001) · Diabetes · doi:10.2337/diabetes.50.5.921 · Cited by 371 · see citing works
Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle
Terada, S., Goto, M., Kato, M., Kawanaka, K., Shimokawa, T., & Tabata, I. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)00881-1 · Cited by 354 · see citing works
Fujii, N., Hayashi, T., Hirshman, M. F., Smith, J. T., Habinowski, S. A., Kaijser, L., Mu, J., Ljungqvist, O., Birnbaum, M. J., Witters, L. A., et al. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3073 · Cited by 351 · see citing works
Gorini, S., Angelis, A. D., Berrino, L., Malara, N., Rosano, G. M. C., & Ferraro, E. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/7582730 · Cited by 329 · see citing works
Contraction signaling to glucose transport in skeletal muscle
Jessen, N., & Goodyear, L. J. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00175.2005 · Cited by 311 · see citing works
Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle
Park, S. H., Gammon, S. R., Knippers, J. D., Paulsen, S. R., Rubink, D. S., & Winder, W. W. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00071.2002 · Cited by 310 · see citing works
Self-citationActivation of p38 MAP kinase enhances sensitivity of muscle glucose transport to insulin
Geiger, P. C., Wright, D. C., Han, D., & Holloszy, J. O. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00477.2004 · Cited by 306 · see citing works
AMPK and Exercise: Glucose Uptake and Insulin Sensitivity
O'Neill, H. M. (2013) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2013.37.1.1 · Cited by 295 · see citing works
Invited Review: Intracellular signaling in contracting skeletal muscle
Sakamoto, K., & Goodyear, L. J. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00167.2002 · Cited by 260 · see citing works
AMP-activated protein kinase and the regulation of glucose transport
FUJII, N. L., Jessen, N., & Goodyear, L. J. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00207.2006 · Cited by 218 · see citing works
AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle
Musi, N., Hayashi, T., FUJII, N. L., Hirshman, M. F., Witters, L. A., & Goodyear, L. J. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.5.e677 · Cited by 219 · see citing works
AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise
Ruderman, N. B., Park, H., Kaushik, V. K., Dean, D., Constant, S., Prentki, M., & Saha, A. K. (2003) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01164.x · Cited by 217 · see citing works
Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin
Fisher, J. S., Gao, J., Han, D.-H., Holloszy, J. O., & Nolte, L. A. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2002.282.1.e18 · Cited by 244 · see citing works
Rasmussen, B. B., Holmbäck, U. C., Volpi, E., Morio, B., Paddon‐Jones, D., & Wolfe, R. R. (2002) · Journal of Clinical Investigation · doi:10.1172/jci15715 · Cited by 223 · see citing works
Self-citationModulation of Anthracycline-Induced Cardiotoxicity by Aerobic Exercise in Breast Cancer
Scott, J. M., Khakoo, A. Y., Mackey, J. R., Haykowsky, M. J., Douglas, P. S., & Jones, L. W. (2011) · Circulation · doi:10.1161/circulationaha.111.021774 · Cited by 188 · see citing works
AMP-activated protein kinase: a key system mediating metabolic responses to exercise
HARDIE, D. G. (2004) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000106171.38299.64 · Cited by 165 · see citing works
Vankoningsloo, S., Piens, M., Lecocq, C., Gilson, A., Pauw, A. D., Renard, P., Demazy, C., Houbion, A., Raes, M. J., & Arnould, T. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400464-jlr200 · Cited by 162 · see citing works
Décombaz, J., Schmitt, B., Ith, M., Decarli, B., Diem, P., Kreis, R., Hoppeler, H. H., & Boesch, C. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.281.3.r760 · Cited by 154 · see citing works
Cartee, G. D. (2015) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00416.2015 · Cited by 140 · see citing works
REGULATION OF FATTY ACID OXIDATION IN SKELETAL MUSCLE
Rasmussen, B. B., & Wolfe, R. R. (1999) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.19.1.463 · Cited by 136 · see citing works
Self-citationDurante, P. E., Mustard, K. J., Park, S.-H., Winder, W. W., & Hardie, D. G. (2002) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00404.2001 · Cited by 137 · see citing works
Self-citationTerada, S., Yokozeki, T., Kawanaka, K., Ogawa, K., Higuchi, M., Ezaki, O., & Tabata, I. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.6.2019 · Cited by 134 · see citing works
Lemieux, K., Konrad, D., Klip, A., & Marette, A. (2003) · The FASEB Journal · doi:10.1096/fj.02-1125com · Cited by 114 · see citing works
Cholesterol homeostasis: Researching a dialogue between the brain and peripheral tissues
Gliozzi, M., Musolino, V., Bosco, F., Scicchitano, M., Scarano, F., Nucera, S., Zito, M. C., Ruga, S., Carresi, C., Macrì, R., et al. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105215 · Cited by 92 · see citing works
Ogasawara, R., Sato, K., Matsutani, K., Nakazato, K., & Fujita, S. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00647.2013 · Cited by 83 · see citing works
5??? Adenosine Monophosphate-Activated Protein Kinase, Metabolism and Exercise
Aschenbach, W. G., Sakamoto, K., & Goodyear, L. J. (2004) · Sports Medicine · doi:10.2165/00007256-200434020-00003 · Cited by 80 · see citing works
The Importance of Fatty Acids as Nutrients during Post-Exercise Recovery
Lundsgaard, A.-M., Fritzen, A. M., & Kiens, B. (2020) · Nutrients · doi:10.3390/nu12020280 · Cited by 72 · see citing works
“In rat skeletal muscle, ACC activity and malonyl-CoA content remained suppressed, and FA oxidation enhanced 90 min after 30 min treadmill exercise, indicating that the ACC-malonyl-CoA-CPT1 axis post-exercise adds to the increased FA entrance into mitochondria and thus FA oxidation [68].”
BackgroundInsulin signalling: effects of prior exercise
Wojtaszewski, J. F. P., Jørgensen, S. B., Frøsig, C., MacDonald, C., Birk, J. B., & Richter, E. A. (2003) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01151.x · Cited by 68 · see citing works
Regulation of GLUT4 traffic and function by insulin and contraction in skeletal muscle
Marette, A. (2003) · Frontiers in bioscience · doi:10.2741/1137 · Cited by 65 · see citing works
Acute resistance exercise-induced IGF1 expression and subsequent GLUT4 translocation
Kido, K., Ato, S., Yokokawa, T., Makanae, Y., Sato, K., & Fujita, S. (2016) · Physiological Reports · doi:10.14814/phy2.12907 · Cited by 62 · see citing works
Bradley, E. A., Eringa, E. C., Stehouwer, C. D. A., Korstjens, I. J. M., Amerongen, G. P. V. N., Musters, R. J. P., Sipkema, P., Clark, M. G., & Rattigan, S. (2010) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.110.204404 · Cited by 62 · see citing works
Kim, J., Solis, R. S., Arias, E. B., & Cartee, G. D. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00909.2003 · Cited by 60 · see citing works
Lefort, N., St.-Amand, E., Morasse, S., Côté, C. H., & Marette, A. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90362.2008 · Cited by 57 · see citing works
Hancock, C. R., Janssen, E., & Terjung, R. L. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00885.2005 · Cited by 55 · see citing works
Self-citationFritzen, A. M., Lundsgaard, A., Jeppesen, J. F., Christiansen, M. L. B., Biensø, R. S., Dyck, J. R. B., Pilegaard, H., & Kiens, B. (2015) · The Journal of Physiology · doi:10.1113/jp270821 · Cited by 45 · see citing works
Dreyer, H. C., Drummond, M. J., Glynn, E. L., Fujita, S., Chinkes, D. L., Volpi, E., & Rasmussen, B. B. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90562.2008 · Cited by 40 · see citing works
Self-citationMerrill, J. F., Thomson, D. M., Hardman, S. E., Hepworth, S. D., Willie, S., & Hancock, C. R. (2012) · Nutrition & Metabolism · doi:10.1186/1743-7075-9-104 · Cited by 27 · see citing works
Self-citationMorissette, M., Susser, S. E., Stammers, A. N., O’Hara, K. A., Gardiner, P. F., Sheppard, P. C., Moffatt, T. L., & Duhamel, T. A. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00092.2014 · Cited by 26 · see citing works
Ambery, A. G., Tackett, L., Penque, B. A., Brozinick, J. T., & Elmendorf, J. S. (2017) · Physiological Reports · doi:10.14814/phy2.13363 · Cited by 23 · see citing works
Takahashi, Y., Terada, S., Banjo, M., Seike, K., Nakano, S., & Hatta, H. (2019) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2018-0860 · Cited by 22 · see citing works
Rubink, D. S., & Winder, W. W. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00621.2004 · Cited by 22 · see citing works
Self-citationFrøsig, C., Roepstorff, C., Brandt, N., Maarbjerg, S. J., Birk, J. B., Wojtaszewski, J. F. P., Richter, E. A., & Kiens, B. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90556.2008 · Cited by 21 · see citing works
Mechanisms in Exercise-Induced Increase in Glucose Disposal in Skeletal Muscle
Ojuka, E. O., & Goyaram, V. (2014) · Medicine and sport science/Medicine and sport · doi:10.1159/000357337 · Cited by 15 · see citing works
Iwasa, M., Takezoe, S., Kitaura, N., Sutani, T., Miyazaki, H., & Aoi, W. (2020) · Experimental Physiology · doi:10.1113/ep088770 · Cited by 15 · see citing works
Cho, C., & Lee, S. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25179274 · Cited by 13 · see citing works
Yang, Y., Jiang, Z., Bolnick, A. D., Dai, J., Puscheck, E. E., & Rappolee, D. A. (2016) · Journal of Reproduction and Development · doi:10.1262/jrd.2016-110 · Cited by 13 · see citing works
Essén-Gustavsson, B., Granlund, A., Benziane, B., Jensen-Waern, M., & Chibalin, A. (2011) · Experimental Physiology · doi:10.1113/expphysiol.2011.057620 · Cited by 9 · see citing works
Roberts, B. M., Geddis, A. V., Ciuciu, A., Reynoso, M., Mehta, N. K., Varanoske, A. N., Kelley, A. M., Walker, R., Munoz, R., Kolb, A. L., et al. (2024) · The FASEB Journal · doi:10.1096/fj.202302642r · Cited by 6 · see citing works
Kotake, H., Ogura, Y., Yamada, S., Inoue, K., Watanabe, S., Ichikawa, D., Sugaya, T., Ohata, K., Natsuki, Y., Hoshino, S., et al. (2023) · The Journal of Physiological Sciences · doi:10.1186/s12576-023-00865-5 · Cited by 6 · see citing works
de Carvalho, C. D., Valentim, R. R., Navegantes, L. C. C., & Papoti, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-22958-8 · Cited by 5 · see citing works
Réponses du muscle à l'exercice et récupération
Bigard, A. X. (2004) · Science & Sports · doi:10.1016/j.scispo.2004.06.005 · Cited by 5 · see citing works
Skeletal muscle signaling response to concurrent endurance and resistance exercise
Makanae, Y., Ogasawara, R., & Fujita, S. (2015) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.4.217 · Cited by 3 · see citing works
Feng, Z., Ying, W., & Jun, W. (2026) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2025.1692399 · Cited by 2 · see citing works
Kwak, S. E., Zheng, A., Arias, E. B., Wang, H., Pan, X., Yue, Y., Duan, D., & Cartee, G. D. (2024) · PLoS ONE · doi:10.1371/journal.pone.0295964 · Cited by 2 · see citing works
Takahashi, Y., Matsumoto, T., Wang, W., Inaba, T., Terada, S., & Hatta, H. (2025) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00311.2025 · Cited by 2 · see citing works
Ribeiro, H. Q. T., Camargo, R. G., Lima, W. P., Zanuto, R., & Carnevali, L. C. (2011) · Revista Brasileira de Fisiologia do Exercício · doi:10.33233/rbfe.v10i2.3431 · Cited by 2 · see citing works
Gunner, F. (2012) · Nottingham ePrints (University of Nottingham) · Cited by 2 · see citing works
Effects of Heat Stress on Energetic Metabolism in Rats
Sanders, S. R. (2010) · UA Campus Repository (The University of Arizona) · Cited by 2 · see citing works
Uno, H., Isemura, M., Kamiya, S., Akimoto, R., Hosoki, K., Tadano, S., Kouzaki, K., Tamura, Y., Kotani, T., & Nakazato, K. (2025) · PLoS ONE · doi:10.1371/journal.pone.0334691 · Cited by 1 · see citing works
Tikkanen, H. O. (2001) · Työväentutkimus Vuosikirja · Cited by 1 · see citing works
Egan, B. (2008) · Dublin City University Open Access Institutional Repository (Dublin City University)
micein skeletal muscle of adenylate kinase-deficient Contraction-mediated phosphorylation of AMPK is
Hancock, C. R., Janssen, E., Terjung, R. L., Zierath, J. R., Kulkarni, S. S., Karlsson, H., Szekeres, F. L. M., Chibalin, A., Bontemps, F., Oscarsson, J., et al. (2015)
Self-citationThe Role of Pyruvate Dehydrogenase Kinase-4 in Post-Exercise Glycogen Recovery
Herbst, E. A. F. (2011)
Smith, M. M. W. (2013) · QSpace (Queen's University Library)
Skeletal muscle fat metabolism during post-exercise recovery in humans
Kimber, N. E. (2004)
Tabata, I. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91302-7.00001-9
Phosphorylation of Skeletal Muscle Acetyl-CoA Carboxylase by AMPK Enhances Palmitoyl-CoA Inhibition
Rubink, D. S. (2004) · ScholarsArchive (Brigham Young University)
- Authors
- Rasmussen, B. B., Hancock, C. R., & Winder, W. W.
- Affiliations
- Brigham Young University (US)
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1998-11-01
- Volume
- 85
- Issue
- 5
- Pages
- 1629-1634
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2180234751
- Cited by
- 78
- References
- 32
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 1 · 2022: 2 · 2020: 4 · 2019: 1 · 2018: 1 · 2017: 3 · 2016: 2 · 2015: 4 · 2014: 3 · 2013: 2 · 2012: 2
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Journal of Applied Physiology (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR041438, AR-41438)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Metabolism, Diabetes, and Cancer
- Keywords
- post-exercise recovery, skeletal muscle, malonyl-CoA, acetyl-CoA carboxylase, AMPK, fat oxidation, fatty acid oxidation inhibition, respiratory exchange ratio, sprint exercise, endurance exercise, exercise energy metabolism
- MeSH terms
- Acetyl-CoA Carboxylase, Animals, Blood Glucose, Physical Exertion, Fatty Acids, Nonesterified, Kinetics, Male, Malonyl Coenzyme A, Multienzyme Complexes, Protein Kinases, Pulmonary Gas Exchange, Rats, Sprague-Dawley, Protein Serine-Threonine Kinases, Muscle, Skeletal, Lactic Acid, Rats, AMP-Activated Protein Kinases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
