The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Invited Review: Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance
Abstract
Cells from virtually all organisms respond to a variety of stresses by the rapid synthesis of a highly conserved set of polypeptides termed heat shock proteins (HSPs). The precise functions of HSPs are unknown, but there is considerable evidence that these stress proteins are essential for survival at both normal and elevated temperatures. HSPs also appear to play a critical role in the development of thermotolerance and protection from cellular damage associated with stresses such as ischemia, cytokines, and energy depletion. These observations suggest that HSPs play an important role in both normal cellular homeostasis and the stress response. This mini-review examines recent evidence and hypotheses suggesting that the HSPs may be important modifying factors in cellular responses to a variety of physiologically relevant conditions such as hyperthermia, exercise, oxidative stress, metabolic challenge, and aging.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Free radicals and tissue damage produced by exercise
Davies, K. J. A., Quintanilha, A. T., Brooks, G. A., & Packer, L. (1982) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(82)80124-1 · Cited by 1,739
Cited by
Kregel, K. C., & Zhang, H. J. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00327.2006 · Cited by 883
Self-citationStress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
Westerheide, S. D., Anckar, J., Stevens, S. M., Sistonen, L., & Morimoto, R. I. (2009) · Science · doi:10.1126/science.1165946 · Cited by 639
A review on the mechanisms of blood-flow restriction resistance training-induced muscle hypertrophy
Pearson, S. J., & Hussain, S. R. (2015) · Sports Medicine · doi:10.1007/s40279-014-0264-9 · Cited by 592
Sawka, M. N., Leon, L. R., Montain, S. J., & Sonna, L. A. (2011) · Comprehensive Physiology · doi:10.1002/cphy.c100082 · Cited by 470
Johnson, J. D., & Fleshner, M. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.0905523 · Cited by 251
Brostrom, M. A., & Brostrom, C. O. (2003) · Cell Calcium · doi:10.1016/s0143-4160(03)00127-1 · Cited by 197
Mitohormesis in exercise training
Merry, T. L., & Ristow, M. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.11.032 · Cited by 176
Biochemical changes in response to intensive resistance exercise training in the elderly
Bautmans, I., Njemini, R., Vasseur, S., Chabert, H., Moens, L., Demanet, C., & Mets, T. (2005) · Gerontology · doi:10.1159/000085122 · Cited by 98
Folguera, G., Bastías, D. A., Caers, J., Rojas, J. M., Piulachs, M.-D., Bellés, X., & Bozinovic, F. (2011) · Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2011.03.002 · Cited by 98
Hsp90 inhibitors as senolytic drugs to extend healthy aging
Fuhrmann-Stroissnigg, H., Niedernhofer, L. J., & Robbins, P. D. (2018) · Cell Cycle · doi:10.1080/15384101.2018.1475828 · Cited by 92
Effect of Heat Shock Protein 70 Polymorphism on Thermotolerance in Tharparkar Cattle
Bhat, S., Kumar, P., Kashyap, N., Deshmukh, B., Dige, M. S., Bhushan, B., Chauhan, A., Kumar, A., & Singh, G. (2016) · Veterinary World · doi:10.14202/vetworld.2016.113-117 · Cited by 73
Astaxanthin intake attenuates muscle atrophy caused by immobilization in rats
Shibaguchi, T., Yamaguchi, Y., Miyaji, N., Yoshihara, T., Naito, H., Goto, K., Ohmori, D., Yoshioka, T., & Sugiura, T. (2016) · Physiological Reports · doi:10.14814/phy2.12885 · Cited by 46
In utero heat stress increases postnatal core body temperature in pigs1,2
Johnson, J. S., Sanz Fernandez, M. V., Seibert, J. T., Ross, J. W., Lucy, M. C., Safranski, T. J., Elsasser, T. H., Kahl, S., Rhoads, R. P., & Baumgard, H. (2015) · Journal of Animal Science · doi:10.2527/jas.2015-9112 · Cited by 29
Liu, K., Hao, X., Wang, Q., Hou, J., Lai, X., Dong, Z., & Shao, C. (2019) · PeerJ · doi:10.7717/peerj.7781 · Cited by 22
Hajati, H., Zaghari, M., Noori, O., Negarandeh, R., & de Oliveira, H. C. (2021) · Italian Journal of Animal Science · doi:10.1080/1828051x.2021.1910582 · Cited by 18
Selection Signal Analysis Reveals Hainan Yellow Cattle Are Being Selectively Bred for Heat Tolerance
Wang, L., Yan, X., Wu, H., Wang, F., Zhong, Z., Zheng, G., Xiao, Q., Wu, K., & Na, W. (2024) · Animals · doi:10.3390/ani14050775 · Cited by 5
Metadata
- Authors
- Kregel, K. C.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 2002-05-01
- Volume
- 92
- Issue
- 5
- Pages
- 2177-2186
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2023746083
- Cited by
- 1,455
- References
- 1
- FWCI
- 12.85
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
