Sarcopenia: Aging-Related Loss of Muscle Mass and Function

Larsson, Lars, Degens, Hans, Li, Meishan, Salviati, Leonardo, Lee, Young il, Thompson, Wesley, Kirkland, James L., Sandri, Marco·2019·Physiological Reviews

Cites (997)

Items 601–800 of 997

  1. Stretch and force generation induce rapid hypertrophy and myosin isoform gene switching in adult skeletal muscle
    Geoffrey Goldspink, Andrew M. Scutt, Jane Martindale, Thomas Jaenicke, Lucien Turay, Gerald-F. Gerlach · 1991 · Biochemical Society Transactions
  2. Mitochondrial dysfunction and neuromuscular disease
    Rachel A. Nardin, Donald R. Johns · 2001 · Muscle & Nerve
  3. WldS and PGC-1α Regulate Mitochondrial Transport and Oxidation State after Axonal Injury
    Kelley C. O’Donnell, Mauricio E. Vargas, Alvaro Sagasti · 2013 · Journal of Neuroscience
  4. Differential changes in the end-plate architecture of functionally diverse muscles during aging
    Julie L. Rosenheimer, Dean O. Smith · 1985 · Journal of Neurophysiology
  5. Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians
    Sally Spendiff, Madhusudanarao Vuda, Gilles Gouspillou, Sudhakar Aare, Anna Pérez, José A. Morais, Robert Thomas Jagoe, Marie‐Eve Filion, Robin Glicksman, Sophia Kapchinsky et al. · 2016 · The Journal of Physiology
  6. Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody
    Sarah Cantor, Wei Zhang, Nicolas Delestrée, Leonor Remédio, George Z. Mentis, Steven J. Burden · 2018 · eLife
  7. Insulin‐like growth factor‐1 prevents age‐related decrease in specific force and intracellular Ca2+ in single intact muscle fibres from transgenic mice
    Estela González, Marı́a Laura Messi, Zhenlin Zheng, Osvaldo Delbono · 2003 · The Journal of Physiology
  8. Effects of aging and gender on the spatial organization of nuclei in single human skeletal muscle cells
    Alexander Cristea, Rizwan Qaisar, Patrick Karlsson Edlund, Joakim Lindblad, Ewert W. Bengtsson, Lars Larsson · 2010 · Aging Cell
  9. Use of motor units in relation to muscle fiber type and size in man
    Finnbogi Jakobsson, Kristian Borg, Lars Edström · 1988 · Muscle & Nerve
  10. Biochemical and Histochemical Changes in Energy Supply-Enzyme Pattern of Muscles of the Rat during Old Age
    A Bass, ERNEST GUTMANN, Věra Hanzlíková · 2009 · Gerontologia
  11. Neurogenesis of Excitation-Contraction Uncoupling in Aging Skeletal Muscle
    Anthony Michael Payne, Osvaldo Delbono · 2004 · Exercise and Sport Sciences Reviews
  12. The Human Skeletal Muscle Proteome Project: a reappraisal of the current literature
    Marta González‐Freire, Richard D. Semba, Ceereena Ubaida‐Mohien, Elisa Fabbri, Paul Scalzo, Kurt Højlund, Craig P. Dufresne, Alexey E. Lyashkov, Luigi Ferrucci · 2016 · Journal of Cachexia Sarcopenia and Muscle
  13. Association between Shear Stress, Angiogenesis, and VEGF in Skeletal Muscles In Vivo
    Małgorzata Milkiewicz, M. D. Brown, Stuart Egginton, OLGA HUDLICKÁ · 2001 · Microcirculation
  14. p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice
    Kunihiro Sakuma, Masakazu Kinoshita, Yoshinori Ito, Miki Aizawa, Wataru Aoi, Akihiko Yamaguchi · 2015 · Journal of Cachexia Sarcopenia and Muscle
  15. Effect of Inflammation on the Aging Microcirculation: Impact on Skeletal Muscle Blood Flow Control
    Geoffrey W. Payne · 2006 · Microcirculation
  16. Muscle capillarization, O2diffusion distance, and V˙ o 2kinetics in old and young individuals
    Philip David Chilibeck, Donald H. Paterson, D. A. Cunningham, A. W. Taylor, Earl G. Noble · 1997 · Journal of Applied Physiology
  17. Denervation stimulates apoptosis but not Id2 expression in hindlimb muscles of aged rats
    Alway, S. E., Degens, H., Krishnamurthy, G., Chaudhrai, A. · 2003 · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
  18. Frameworks for proof-of-concept clinical trials of interventions that target fundamental aging processes
    Justice, Jamie, Miller, Jordan D., Newman, John C., Hashmi, Shahrukh K., Halter, Jeffrey, Austad, Steve N., Barzilai, Nir, Kirkland, James L. · 2016 · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
  19. Absence of relationship between the level of electron transport chain activities and aging in human skeletal muscle
    Barrientos, Antoni, Casademont, Jordi, Rötig, Agnès, Miró, Òscar, Urbano-Márquez, Álvaro, Rustin, Pierre, Cardellach, Francesc · 1996 · Biochemical and Biophysical Research Communications
  20. The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo‐controlled, Phase III study in patients with myelofibrosis
    Srđan Verstovšek, Ruben A. Mesa, Jason R. Gotlib et al. · 2013 · British Journal of Haematology
  21. Isometric, shortening, and lengthening contractions of muscle fiber segments from adult and old mice
    Susan V. Brooks, John A. Faulkner · 1994 · American Journal of Physiology-Cell Physiology
  22. Resistance Training Increases Skeletal Muscle Capillarization in Healthy Older Men
    Lex B. Verdijk, Tim Snijders, Tanya M. Holloway, Janneau M.X. van Kranenburg, Luc J. C. van Loon · 2016 · Medicine & Science in Sports & Exercise
  23. HISTOLOGIC VARIATIONS WITH AGE IN APPARENTLY NORMAL PERIPHERAL NERVE TRUNKS
    Lillian Cottrell · 1940 · Archives of Neurology And Psychiatry
  24. Blood vessels and desmin control the positioning of nuclei in skeletal muscle fibers
    Evelyn Ralston, Zhuomei Lu, N. Biscocho, Elisavet Soumaka, Manolis Mavroidis, Clara Prats, Terje Lømo, Yassemi Capetanaki, Thorkil Ploug · 2006 · Journal of Cellular Physiology
  25. Age-Associated Power Decline from Running, Jumping, and Throwing Male Masters World Records
    Paolo Gava, Helmut Kern, Ugo Carraro · 2015 · Experimental Aging Research
  26. Circadian clocks govern calorie restriction—mediated life span extension through BMAL1‐ and IGF‐1‐dependent mechanisms
    Patel, Sonal A., Chaudhari, Amol, Gupta, Richa, Velingkaar, Nikkhil, Kondratov, Roman V. · 2016 · The FASEB Journal
  27. Evidence that specific mtDNA point mutations may not accumulate in skeletal muscle during normal human aging.
    Francesco Pallotti, X Chen, Eduardo Bonilla, Eric A. Schon · 1996 · PubMed Central
  28. Changes in the capillarity of skeletal muscle in the growing rat
    E. Ripoll, A. H. Sillau, Natalio Banchero · 1979 · Pflügers Archiv - European Journal of Physiology
  29. Presence in brain of a mitogenic agent promoting proliferation of myoblasts in low density culture
    Denis Gospodarowicz, James Weseman, John S. Moran · 1975 · Nature
  30. Overexpression of the Coq8 Kinase in Saccharomyces cerevisiae coq Null Mutants Allows for Accumulation of Diagnostic Intermediates of the Coenzyme Q6 Biosynthetic Pathway
    Letian X. Xie, Mohammad Ozeir, Jeniffer Y. Tang, Jia Y. Chen, Sylvie-Kieffer Jaquinod, Marc Fontecave, Catherine Freitag Clarke, Fabien Pierrel · 2012 · Journal of Biological Chemistry
  31. FoxO‐dependent atrogenes vary among catabolic conditions and play a key role in muscle atrophy induced by hindlimb suspension
    Brocca, Lorenza, Toniolo, Luana, Reggiani, Carlo, Bottinelli, Roberto, Sandri, Marco, Pellegrino, Maria Antonietta · 2017 · The Journal of Physiology
  32. Glycation of rat sciatic nerve tubulin in experimental diabetes mellitus
    Nicky A Cullum, Jeff L. Mahon, K. Stringer · 1991 · Diabetologia
  33. Effect of aging and late onset dietary restriction on antioxidant enzymes and proteasome activities, and protein carbonylation of rat skeletal muscle and tendon
    Zsolt O. Radak, Ryoya Takahashi, Atsushi Kumiyama, Hideko Nakamoto, Hideki Ohno, Tomomi Ookawara, Sataro Goto · 2002 · Experimental Gerontology
  34. INJURY TO SKELETAL MUSCLES OF MICE BY FORCED LENGTHENING DURING CONTRACTIONS
    John A. Faulkner, David Arthur Jones, Joan M. Round · 1989 · Quarterly Journal of Experimental Physiology
  35. In vitro motility speed of slow myosin extracted from single soleus fibres from young and old rats
    Peter Höök, Xiaopeng Li, John Sleep, Simon M. Hughes, Lars Larsson · 1999 · The Journal of Physiology
  36. Prolonged acute mechanical ventilation and hospital bed utilization in 2020 in the United States: implications for budgets, plant and personnel planning
    Marya D. Zilberberg, Andrew F. Shorr · 2008 · BMC Health Services Research
  37. Myofibrillar-protein isoforms and sarcoplasmic-reticulum Ca2+-transport activity of single human muscle fibres
    G. Salviati, Romeo Betto, Daniela Danieli‐Betto, Massimo Zeviani · 1984 · Biochemical Journal
  38. Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis
    Scot R. Kimball, James P. O’Malley, Joshua C. Anthony, Stephen J. Crozier, Leonard S. Jefferson · 2004 · American Journal of Physiology-Endocrinology and Metabolism
  39. Early‐onset calorie restriction conserves fiber number in aging rat skeletal muscle
    Susan H. McKiernan, Entela A. Bua, Jennifer McGorray, Judd M. Aiken · 2004 · The FASEB Journal
  40. Glycolytic fast‐twitch muscle fiber restoration counters adverse age‐related changes in body composition and metabolism
    Yuichi Akasaki, Noriyuki Ouchi, Yasuhiro Izumiya, Barbara L. Bernardo, Nathan K. LeBrasseur, Kenneth Walsh · 2013 · Aging Cell
  41. Physiological properties of two antagonistic human muscle groups
    A. Y. Belanger, Alan J. McComas, G. B. C. Elder · 1983 · European Journal of Applied Physiology
  42. Mitochondrial coenzyme Q content and aging
    Achim Lass, Linda K. Kwong, Rajindar S. Sohal · 1999 · BioFactors
  43. Slowing with age of the rate of slow axonal flow in bifurcating axons of rat dorsal root ganglion cells
    Yoshiaki Komiya · 1980 · Brain Research
  44. Fiber-type composition of nine rat muscles. I. Changes during the first year of life
    C. A. Maltin, Margaret I. Delday, A. G. Baillie · 1989 · American Journal of Physiology-Endocrinology and Metabolism
  45. EFFECT OF AGE ON VOLUNTARY FORCE AND CROSS‐SECTIONAL AREA OF HUMAN ADDUCTOR POLLICIS MUSCLE
    Stuart Bruce, D. Newton, R. C. Woledge · 1989 · Quarterly Journal of Experimental Physiology
  46. Reduced TrkB expression results in precocious age-like changes in neuromuscular structure, neurotransmission, and muscle function
    Scott A. Kulakowski, Sara D. Parker, Kirkwood E. Personius · 2011 · Journal of Applied Physiology
  47. Association of C-reactive protein and muscle strength in the English Longitudinal Study of Ageing
    Mark Hamer, Gerard J. Molloy · 2009 · AGE
  48. Effects of excessive use of remaining muscle fibers in prior polio and LV lesion
    Kristian Borg, Jörgen Borg, Lars Edström · 1988 · Muscle & Nerve
  49. Physiological adaptations to resistance exercise as a function of age
    B. Phillips, John P. Williams, P. Greenhaff, K. Smith, P. Atherton · 2017 · JCI Insight
  50. Aging rat neuromuscular junnctions: A morphometric study of cholinesterase‐stained whole mounts and ultrastructure
    Constance Ann Cardasis, Donna LaFontaine · 1987 · Muscle & Nerve
  51. Physiological factors influencing capillary growth
    Stuart Egginton · 2010 · Acta Physiologica
  52. The relationship between capillarisation and fibre types during compensatory hypertrophy of the plantaris muscle in the rat.
    Hans Degens, Z. Turek, Louis J. C. Hoofd · 1992 · PubMed
  53. Growth and Muscle Defects in Mice Lacking Adult Myosin Heavy Chain Genes
    Leslie Acakpo‐Satchivi, Winfried Edelmann, Carol A. Sartorius, Brian D. Lu, Philip A. Wahr, Simon C. Watkins, Joseph M. Metzger, Leslie Anne Leinwand, Raju Kucherlapati · 1997 · The Journal of Cell Biology
  54. Myosin and actin expression and oxidation in aging muscle
    LaDora V. Thompson, David Durand, N. A. Fugere, Deborah A. Ferrington · 2006 · Journal of Applied Physiology
  55. Reversing the Outcome of Synapse Elimination at Developing Neuromuscular Junctions In Vivo: Evidence for Synaptic Competition and Its Mechanism
    Stephen G. Turney, Jeff William Lichtman · 2012 · PLoS Biology
  56. Maximum shortening velocity and myosin isoforms in single muscle fibers from young and old rats
    X. Li, Lars Larsson · 1996 · American Journal of Physiology-Cell Physiology
  57. Oxidative proteome alterations during skeletal muscle ageing.
    Lourenço dos Santos, Sofia, Baraibar, Martin A., Lundberg, Staffan, Eeg-Olofsson, Orvar, Larsson, Lars, Friguet, Bertrand · 2015 · Redox Biology
  58. Hormone replacement therapy improves contractile function and myonuclear organization of single muscle fibres from postmenopausal monozygotic female twin pairs
    Rizwan Qaisar, Guillaume Renaud, Yvette Hedström, Eija Pöllänen, Paula H. A. Ronkainen, Jaakko A. Kaprio, Markku Alén, Sarianna Sipilä, Konstantin A. Artemenko, Jonas Bergquist et al. · 2013 · The Journal of Physiology
  59. Severe depletion of mitochondrial DNA in spinal muscular atrophy
    Alexandra Berger, Johannes Adalbert Mayr, David Meierhofer, Ulrike Fötschl, Reginald E. Bittner, Herbert Budka, Claude Grethen, Michael Huemer, Barbara Kofler, Wolfgang Sperl · 2003 · Acta Neuropathologica
  60. Age-associated decrease in contraction-induced activation of downstream targets of Akt/mTor signaling in skeletal muscle
    Katsuhiko Funai, Jascha D. Parkington, Silvia Ferreira Carámbula, Roger A. Fielding · 2005 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  61. The Psychology of Human Ageing
    Isadore Green · 1975 · American Journal of Psychiatry
  62. Effect of chronic disuse of rat soleus neuromuscular junctions on postsynaptic membrane.
    G D Fischbach, N. Robbins · 1971 · Journal of Neurophysiology
  63. Structure and function of human muscle fibres and muscle proteome in physically active older men
    Lorenza Brocca, Jamie Stewart McPhee, Emanuela Longa, Monica Canepari, Olivier Seynnes, Giuseppe DE VITO, Maria Antonietta Pellegrino, Marco Vincenzo Narici, Roberto Bottinelli · 2017 · The Journal of Physiology
  64. Effects of ageing on enzyme-histochemical, morphometrical and contractile properties of the soleus muscle in the rat
    Tor Ansved, Lars Larsson · 1989 · Journal of the Neurological Sciences
  65. Effects of ageing and exercise on soleus and extensor digitorum longus muscles of female rats
    M. Brown, T.P. Ross, J. O. Holloszy · 1992 · Mechanisms of Ageing and Development
  66. N-CAM, 43K-Rapsyn, and S-Laminin mRNAs Are Concentrated at Synaptic Sites in Muscle Fibers
    Lisa M. Moscoso, John Paul Merlie, Joshua R. Sanes · 1995 · Molecular and Cellular Neuroscience
  67. Sarcopenia Accelerates at Advanced Ages in Fisher 344xBrown Norway Rats
    Entela B. Lushaj, Julene K. Johnson, Debbie I. McKenzie, Judd M. Aiken · 2008 · The Journals of Gerontology Series A
  68. Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions
    Young Il Lee, Yue Li, Michelle Mikesh, Ian Smith, Klaus‐Armin Nave, Markus H. Schwab, Wesley J. Thompson · 2016 · Proceedings of the National Academy of Sciences
  69. Mitochondrial Effects of Antiretroviral Therapies in Asymptomatic Patients
    Sònia López, Òscar Miró, Estebán Martínez et al. · 2004 · Antiviral Therapy
  70. Age-Related Change in Skeletal Muscle Blood Flow in the Rat
    Glenn L. Irion, Usha S. Vasthare, Ronald F. Tuma · 1987 · Journal of Gerontology
  71. Late effects of polio: Critical review of the literature on neuromuscular function
    James C. Agre, Arthur A. Rodriquez, John A. Tafel · 1991 · Archives of Physical Medicine and Rehabilitation
  72. Calorie restriction-induced weight loss and exercise have differential effects on skeletal muscle mitochondria despite similar effects on insulin sensitivity
    Menshikova, Elizaveta V, Ritov, Vladimir B, Dube, John J, Amati, Francesca, Stefanovic-Racic, Maja, Toledo, Frederico G S, Coen, Paul M, Goodpaster, Bret H · 2018 · The Journals of Gerontology Series A
  73. Regulation of isometric contraction in skeletal muscle
    Irwin A. Brody · 1976 · Experimental Neurology
  74. Quadriplegic areflexic ICU illness: Selective thick filament loss and normal nerve histology
    Howard W. Sander, Marianna Golden, Moris J. Danon · 2002 · Muscle & Nerve
  75. Effects of Testosterone on Skeletal Muscle Architecture in Intermediate-Frail and Frail Elderly Men
    Ross A. Atkinson, Upendram Srinivas-Shankar, Stephen A. Roberts, Martin Joseph Connolly, Judith E. Adams, Jackie A Oldham, Frederick C. W. Wu, Olivier Seynnes, Claire Elizabeth Stewart, Constantinos N. Maganaris et al. · 2010 · The Journals of Gerontology Series A
  76. Body composition, aerobic capacity, and density of muscle capillaries in young and old men.
    Jana Pařízková, E Eiselt, S Sprynarová, M Wachtlová · 1971 · Journal of Applied Physiology
  77. Exercise, Nutrition, and Aging
    William J. Evans · 1995 · Clinics in Geriatric Medicine
  78. Physical exercise increases Sestrin 2 protein levels and induces autophagy in the skeletal muscle of old mice
    Lenhare, Luciene, Crisol, Barbara M., Silva, Vagner R.R., Katashima, Carlos K., Cordeiro, André V., Pereira, Karina D., Luchessi, Augusto D., da Silva, Adelino S.R., Cintra, Dennys E., Moura, Leandro P. et al. · 2017 · Experimental Gerontology
  79. Age-related human mtDNA deletions: a heterogeneous set of deletions arising at a single pair of directly repeated sequences.
    Alessandra Baumer, Chunfang Zhang, Anthony W. Linnane, Phillip Nagley · 1994 · PubMed Central
  80. Increased muscle blood supply and transendothelial nutrient and insulin transport induced by food intake and exercise: effect of obesity and ageing
    Wagenmakers, Anton J. M., Strauss, Juliette A., Shepherd, Sam O., Keske, Michelle A., Cocks, Matthew · 2016 · The Journal of Physiology
  81. Mechanical and histochemical characterization of skeletal muscles from senescent rats
    Thomas J. Eddinger, ROBERT G. CASSENS, R L Moss · 1986 · American Journal of Physiology-Cell Physiology
  82. Motor nerve terminal loss from degenerating muscle fibers
    Mark M. Rich, Jeff William Lichtman · 1989 · Neuron
  83. Coenzyme Q deficiency in muscle
    Eva Trevisson, Salvatore DiMauro, Plácido Navas, Leonardo Salviati · 2011 · Current Opinion in Neurology
  84. Myonuclear domain size and myosin isoform expression in muscle fibres from mammals representing a 100 000‐fold difference in body size
    Jing‐Xia Liu, Anna‐Stina Höglund, Patrick Karlsson, Joakim Lindblad, Rizwan Qaisar, Sudhakar Aare, Ewert W. Bengtsson, Lars Larsson · 2008 · Experimental Physiology
  85. Reactive oxygen species in sarcopenia: Should we focus on excess oxidative damage or defective redox signalling?
    Malcolm Joseph Jackson · 2016 · Molecular Aspects of Medicine
  86. Alterations of the in vivo torque-velocity relationship of human skeletal muscle following 30 days exposure to simulated microgravity.
    Gary A. Dudley, M.R. Duvoisin, Víctor A. Convertino, P Buchanan · 1989 · PubMed
  87. Role of PGC-1α in sarcopenia: Etiology and potential intervention—A mini-review
    Ji, Li Li, Kang, Chounghun · 2015 · Gerontology
  88. Deleted mitochondrial DNA in the skeletal muscle of aged individuals.
    M Katayama, M Tanaka, Hiroyuki Yamamoto, Toshihiro Ohbayashi, Y Nimura, T Ozawa · 1991 · PubMed
  89. Changes in motor end-plates resulting from muscle fibre necrosis and regeneration
    Leo W. Duchen, Barbara J. Excell, R. Patel, Betty Smith · 1974 · Journal of the Neurological Sciences
  90. Myosin subunits and contractile properties of single fibers from hypokinetic rat muscles
    Peter J. Reiser, Christine E. Kasper, Richard L. Moss · 1987 · Journal of Applied Physiology
  91. Effects of age and gender on shortening velocity and myosin isoforms in single rat muscle fibres
    Degens, H., Yu, F., Li, X., Larsson, L. · 1998 · Acta Physiologica Scandinavica
  92. AAV-mediated VEGF gene transfer into skeletal muscle stimulates angiogenesis and improves blood flow in a rat hindlimb ischemia model
    M. Shimpo · 2002 · Cardiovascular Research
  93. Insulin-like growth factor-1 and myostatin mRNA expression in muscle: comparison between 62–77 and 21–31 yr old men
    Stephen L. Welle, Kirti S. Bhatt, Bharati Shah, Charles A. Thornton · 2002 · Experimental Gerontology
  94. Axon Withdrawal during Synapse Elimination at the Neuromuscular Junction Is Accompanied by Disassembly of the Postsynaptic Specialization and Withdrawal of Schwann Cell Processes
    Susan M. Culican, Carla C. Nelson, Jeff William Lichtman · 1998 · Journal of Neuroscience
  95. Simulation of motor unit recruitment and microvascular unit perfusion: spatial considerations
    Andrew J. Fuglevand, Steven S. Segal · 1997 · Journal of Applied Physiology
  96. Human Major Psoas Muscle and Sacrospinalis Muscle in Relation to Age: a Study by Computed Tomography
    Keiko Imamura, Hiroshi Ashida, Takuya Ishikawa, M. Fujii · 1983 · Journal of Gerontology
  97. Effects of aging and life-long physical training on collagen in slow and fast skeletal muscle in rats
    Vuokko Kovanen, Harri Suominen, Leena Peltonen · 1987 · Cell and Tissue Research
  98. Ultrastructural evidence of continued reorganization at the aging (11–26 months) rat soleus neuromuscular junction
    Constance Ann Cardasis · 1983 · The Anatomical Record
  99. Uniformity of metabolic enzymes within individual motor units
    P. M. Nemeth, L Solanki, DA Gordon, TM Hamm, Robert M. Reinking, Stuart Dg · 1986 · Journal of Neuroscience
  100. Remodeling of neuromuscular junctions in adult mouse soleus
    DJ Wigston · 1989 · Journal of Neuroscience
  101. Differential effects of aging on motoneurons and peripheral nerves innervating the hindlimb and forelimb muscles of rats
    Ken Hashizume, Kenro Kanda · 1995 · Neuroscience Research
  102. <scp>PGC</scp>‐1α affects aging‐related changes in muscle and motor function by modulating specific exercise‐mediated changes in old mice
    Gill, Jonathan F., Santos, Gesa, Schnyder, Svenia, Handschin, Christoph · 2018 · Aging Cell
  103. Quantitative and qualitative morphological properties of the soleus motor nerve and the L5 ventral root in young and old rats
    Tor Ansved, Lars Larsson · 1990 · Journal of the Neurological Sciences
  104. Single muscle fiber properties in aging and disuse
    Monica Canepari, Maria Antonietta Pellegrino, Giuseppe D’Antona, Roberto Bottinelli · 2009 · Scandinavian Journal of Medicine and Science in Sports
  105. Time course of changes in capillarization in hypertrophied rat plantaris muscle
    Michael J. Plyley, Barbara J. Olmstead, Earl G. Noble · 1998 · Journal of Applied Physiology
  106. Coordinated fast-to-slow transitions of myosin and SERCA isoforms in chronically stimulated muscles of euthyroid and hyperthyroid rabbits
    Nina Hämäläinen, Dirk Pette · 1997 · Journal of Muscle Research and Cell Motility
  107. Progression of age changes in mature mouse motor nerve terminals and its relation to locomotor activity
    N. Robbins, Mohamed Abdelmonem Fahim · 1985 · Journal of Neurocytology
  108. A Study of the Loss of Nerve Cells in the Central Nervous System in Relation to Age
    E. A. Wright, Jean M. Spink · 2009 · Gerontologia
  109. Changes in human skeletal muscles due to ageing
    G Oertel · 1986 · Acta Neuropathologica
  110. Exercise and Longevity: Evidence for a Threshold Age
    Dee W. Edington, Arthur C. Cosmas, William B. McCafferty · 1972 · Journal of Gerontology
  111. The Calcium-binding Proteins S100A8 and S100A9 Initiate the Early Inflammatory Program in Injured Peripheral Nerves
    Andrei V. Chernov, Jennifer Dolkas, Khang Hoang, Mila Angert, Geetha Srikrishna, Thomas Vogl, Svetlana Baranovskaya, Alex Y. Strongin, Veronica I. Shubayev · 2015 · Journal of Biological Chemistry
  112. Ultrastructural evidence indicating reorganization at the neuromuscular junction in the normal rat soleus muscle
    Constance Ann Cardasis, Helen A. Padykula · 1981 · The Anatomical Record
  113. Age-Related Changes in the Microcirculation of Skeletal Muscle
    Hans Degens · 1998 · Advances in experimental medicine and biology
  114. Effect of age on axoplasmic transport of cholinesterase in rat sciatic nerves
    Donald N. McMartin, James A. O'Connor · 1979 · Mechanisms of Ageing and Development
  115. ETS Transcription Factor Erm Controls Subsynaptic Gene Expression in Skeletal Muscles
    Simon Hippenmeyer, Roland M. Huber, David R. Ladle, KENNETH M. M. MURPHY, Silvia Arber · 2007 · Neuron
  116. Is functional hypertrophy and specific force coupled with the addition of myonuclei at the single muscle fiber level?
    Rizwan Qaisar, Guillaume Renaud, Kevin Morine, Elisabeth R. Barton, Hugh Lee Sweeney, Lars Larsson · 2011 · The FASEB Journal
  117. Effects of endurance training on capillary supply of human skeletal muscle on two age groups (20 and 60 years).
    Christian Denis, Jean‐Claude Chatard, D. Dormois, Marie‐Thérèse Linossier, ANDRÉ GEYSSANT, Jean René Lacour · 1986 · PubMed
  118. Relations Between Normal Aging and Disease
    1986 · Journal of Gerontology
  119. Grip work estimation during sustained maximal contraction: Validity and relationship with dependency and inflammation in elderly persons
    Ivan Bautmans, Oscar Okwudiri Onyema, Katrien Van Puyvelde, S. Pleck, Tony F. Mets · 2010 · The journal of nutrition health & aging
  120. The incidence of stairway injuries in Austria
    David Hemenway, Sara J. Solnick, Christian M. Koeck · 1994 · Accident Analysis & Prevention
  121. Effects of age and life-time physical training on fibre composition of slow and fast skeletal muscle in rats
    Vuokko Kovanen, Harri Suominen · 1987 · Pflügers Archiv - European Journal of Physiology
  122. Greater capillary-fiber interface per fiber mitochondrial volume in skeletal muscles of old rats
    Odile A. Mathieu-Costello, Yan Ju, Margarita Trejo, Li Cui · 2005 · Journal of Applied Physiology
  123. Changes in the Nervous System and Musculature of Old Rats
    Gijsbert van Steenis, R. Kroes · 1971 · Veterinary Pathology
  124. Is human skeletal muscle capillary supply modelled according to fibre size or fibre type?
    SK Ahmed, Stuart Egginton, Philip M. Jakeman · 1997 · Experimental Physiology
  125. Mitochondrial Myopathy of Childhood Associated With Mitochondrial DNA Depletion and a Homozygous Mutation (T77M) in the TK2 Gene
    Michelangelo Mancuso, Massimiliano Filosto, Eduardo Bonilla · 2003 · Archives of Neurology
  126. Sarcoplasmic Reticulum Ca2+ Release Declines in Muscle Fibers from Aging Mice
    Ramón Jiménez-Moreno, Zhong-Min Wang, Robert Gerring, Osvaldo Delbono · 2008 · Biophysical Journal
  127. Protein Carbonylation and Heat Shock Proteins in Human Skeletal Muscle: Relationships to Age and Sarcopenia
    Maria Reyes Beltran‐Valls, D. J. Wilkinson, Marco Vincenzo Narici, K. Smith, Bethan Eileen Phillips, Daniela Caporossi, Philip James Atherton · 2014 · The Journals of Gerontology Series A
  128. Aberrant post-translational modifications compromise human myosin motor function in old age
    Meishan Li, Hannah Ogilvie, Julien Ochala, Konstantin A. Artemenko, Hiroyuki Iwamoto, Naoto Yagi, Jonas Bergquist, Lars Larsson · 2015 · Aging Cell
  129. Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice
    Hiroshi Nishimune, Yomna Badawi, Shuuichi Mori, Kazuhiro Shigemoto · 2016 · Scientific Reports
  130. Axonal transport in early experimental diabetes
    Per Sidenius, Johannes Jakobsen · 1979 · Brain Research
  131. Some observations on the skeletal musculature of aged rats
    Kohshiro Fujisawa · 1974 · Journal of the Neurological Sciences
  132. Contraction time, histochemical type, and terminal cisternae volume of rat motor units
    Eric Kugelberg, Lars‐Eric Thornell · 1983 · Muscle & Nerve
  133. Higher C-Reactive Protein and Soluble Tumor Necrosis Factor Receptor Levels Are Associated With Poor Physical Function and Disability: A Cross-Sectional Analysis of a Cohort of Late Middle-Aged African Americans
    Matthew T. Haren, Theodore K. Malmstrom, Douglas K. Miller, Ping Patrick, H. Mitchell Perry, Margaret M. Herning, William A. Banks, J. E. Morley · 2009 · The Journals of Gerontology Series A
  134. Sirtuins in mitochondrial stress: Indispensable helpers behind the scenes
    Shuang‐Zhe Lin, Haiping Xing, Tongtong Zang, Xin Ruan, Lulu Wo, Ming He · 2018 · Ageing Research Reviews
  135. Exercise, Nutrition and Aging ,
    William J. Evans · 1992 · Journal of Nutrition
  136. VEGF Trap Abolishes Shear Stress‐ and Overload‐Dependent Angiogenesis in Skeletal Muscle
    James Leigh Williams, David Cartland, John S. Rudge, Stuart Egginton · 2006 · Microcirculation
  137. Age-related changes of cell death pathways in rat extraocular muscle
    Colleen A. McMullen, Amy L. Ferry, Jorge Luis Gamboa, Francisco H. Andrade, Esther E. Dupont‐Versteegden · 2009 · Experimental Gerontology
  138. Effects of testosterone on lean mass gain in elderly men: systematic review with meta-analysis of controlled and randomized studies
    Neto, Walter Krause, Gama, Eliane Florencio, Rocha, Leandro Yanase, Ramos, Carla Cristina, Taets, Wagner, Scapini, Katia Bilhar, Ferreira, Janaina B., Rodrigues, Bruno, Caperuto, Érico · 2015 · AGE
  139. PKB signaling and atrogene expression in skeletal muscle of aged mice
    Megan Gaugler, Alicia Brown, Erin Merrell, Maria DiSanto‐Rose, John A. Rathmacher, Thomas Reynolds · 2011 · Journal of Applied Physiology
  140. Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons
    Kazuyoshi Shinpo, Seiji Kikuchi, Hidenao Sasaki, Akihiko Ogata, Fumio Moriwaka, Kunio Tashiro · 2000 · Brain Research
  141. Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice
    Jill E. Kolesar, Adeel Safdar, Arkan Abadi, Lauren MacNeil, Justin D. Crane, Mark Andrew Tarnopolsky, Brett A. Kaufman · 2014 · Free Radical Biology and Medicine
  142. Experimental Physiology –Review Article: Tissue capillary supply – it's quality not quantity that counts!
    Stuart Egginton, Eamonn A. Gaffney · 2010 · Experimental Physiology
  143. Alteration of mitochondrial oxidative phosphorylation in aged skeletal muscle involves modification of adenine nucleotide translocator
    Gouspillou, Gilles, Bourdel-Marchasson, Isabelle, Rouland, Richard, Calmettes, Guillaume, Franconi, Jean-Michel, Deschodt-Arsac, Véronique, Diolez, Philippe · 2010 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
  144. Regulation of the Intermediate Filament Protein Nestin at Rodent Neuromuscular Junctions by Innervation and Activity
    Hyuno Kang, Le Tian, Young‐Jin Son, Yi Zuo, Diane Procaccino, Flora M. Love, Christopher R. Hayworth, Joshua T. Trachtenberg, Michelle Mikesh, Lee Sutton et al. · 2007 · Journal of Neuroscience
  145. Regulation of Myogenesis by Fibroblast Growth Factors Requires Beta-Gamma Subunits of Pertussis Toxin-Sensitive G Proteins
    Yuri V. Fedorov, Nathan C. Jones, Bradley B. Olwin · 1998 · Molecular and Cellular Biology
  146. Fiber Capillary Supply Related To Fiber Size And Oxidative Capacity In Human And Rat Skeletal Muscle
    Rob C. I. Wüst, Sarah L. Gibbings, Hans Degens · 2008 · Advances in experimental medicine and biology
  147. Cellular dynamics of regeneration reveals role of two distinct Pax7 stem cell populations in larval zebrafish muscle repair
    Tapan G. Pipalia, Jana Koth, Shukolpa D. Roy, Christina L. Hammond, Koichi Kawakami, Simon M. Hughes · 2016 · Disease Models & Mechanisms
  148. Thyroid hormone regulation of myosin heavy chain isoform composition in young and old rats, with special reference to IIX myosin
    Lars Larsson, U. MÜLLER, X. Li, Stefano Schiaffino · 1995 · Acta Physiologica Scandinavica
  149. Optimization of respiratory chain enzymatic assays in muscle for the diagnosis of mitochondrial disorders
    Marco Spinazzi, Alberto Casarin, Vanessa Pertegato, Mario Ermani, Leonardo Salviati, Corrado Italo Angelini · 2011 · Mitochondrion
  150. Accumulation of severely atrophic myofibers marks the acceleration of sarcopenia in slow and fast twitch muscles
    Sharon L. Rowan, Fennigje M. Purves-Smith, Nathan M. Solbak, Russell T. Hepple · 2011 · Experimental Gerontology
  151. Androgens and aging in men
    Ronald S. Swerdloff, Christina Wang · 1993 · Experimental Gerontology
  152. Initial ultrastructural abnormalities at the motor end plate produced by a cholinesterase inhibitor
    Michael B. Laskowski, William H. Olson, Wolf‐D. Dettbarn · 1977 · Experimental Neurology
  153. Fiber-Type Transitions and Satellite Cell Activation in Low-Frequency-Stimulated Muscles of Young and Aging Rats
    Charles T. Putman, Karim R. Sultan, Thomas Wassmer, Jeremy Andrew Bamford, Dejan Škorjanc, Dirk Pette · 2001 · The Journals of Gerontology Series A
  154. Aerobic power declines with aging in rat skeletal muscles perfused at matched convective O2 delivery
    Russell T. Hepple, Jason L. Hagen, Daniel J. Krause, Cory C. Jackson · 2003 · Journal of Applied Physiology
  155. Nerve Terminal Growth Remodels Neuromuscular Synapses in Mice following Regeneration of the Postsynaptic Muscle Fiber
    Yue Li, Wesley J. Thompson · 2011 · Journal of Neuroscience
  156. Structural and functional changes in the microvasculature of disused skeletal muscle
    Karel Tyml · 2001 · Frontiers in bioscience
  157. Aged skeletal muscle retains the ability to fully regenerate functional architecture
    Antonio S. J. Lee, Judy E. Anderson, Josephine E. Joya, Stewart I. Head, Nalini Pather, Anthony J. Kee, Peter William Gunning, Edna C. Hardeman · 2013 · BioArchitecture
  158. High mTORC1 signaling is maintained, while protein degradation pathways are perturbed in old murine skeletal muscles in the fasted state
    Zoe Rene White, Robert B. White, Christopher McMahon, Miranda D. Grounds, Tea Shavlakadze · 2016 · The International Journal of Biochemistry & Cell Biology
  159. Selective downregulation of ubiquitin conjugation cascade mRNA occurs in the senescent rat soleus muscle
    Keith C. DeRuisseau, Andreas N. Kavazis, Scott K. Powers · 2005 · Experimental Gerontology
  160. Age and exercise training alter signaling through reactive oxygen species in the endothelium of skeletal muscle arterioles
    Amy Lynn Sindler, Rafael Reyes, Bei Chen, Payal Ghosh, Alvaro N. Gurovich, Lori Sunhae Kang, Arturo Juan Cardounel, Michael D. Delp, Judy Marie Muller‐Delp · 2013 · Journal of Applied Physiology
  161. Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases
    M. Flint Beal, Russell T. Matthews · 1997 · Molecular Aspects of Medicine
  162. Hormone replacement therapy enhances IGF ‐1 signaling in skeletal muscle by diminishing miR‐182 and miR‐223 expressions: a study on postmenopausal monozygotic twin pairs
    Fabiola Olivieri, Maarit Ahtiainen, Raffaella Lazzarini, Eija Pöllänen, Miriam Capri, Maria Lorenzi, Gianluca Fulgenzi, Maria Cristina Albertini, Stefano Salvioli, Markku Alén et al. · 2014 · Aging Cell
  163. CHANGE IN FIBRE SIZE, NOT NUMBER, IN AGEING SKELETAL MUSCLE
    Marybeth Brown · 1987 · Age and Ageing
  164. Changes in capillary luminal diameter in rat soleus muscle after hind‐limb suspension
    Kano, Kano, Shimegi · 2000 · Acta Physiologica Scandinavica
  165. Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres
    Saleh Omairi, Antonios Matsakas, Hans Degens, Oliver Kretz, Kenth‐Arne Hansson, Andreas Våvang Solbrå, Jo C. Bruusgaard, Barbara Joch, Roberta Sartori, Natasa Giallourou et al. · 2016 · eLife
  166. Human skeletal myosin heavy chain genes are tightly linked in the order embryonic-IIa-IId/x-IIb-perinatal-extraocular
    Joseph B. Shrager, Philippe R. Desjardins, James M. Burkman, Stéphane Koenig, Douglas R. Stewart, Leonard T. Su, Megha C. Shah, Evelyn Bricklin, Manu Tewari, Rebecca K. Hoffman et al. · 2000 · Journal of Muscle Research and Cell Motility
  167. Ageing and isokinetic plantar flexion
    D. A. Cunningham, Deric Morrison, Charles L. Rice, Carlton Brian Cooke · 1987 · European Journal of Applied Physiology
  168. Effects of Fiber Type and Size on the Heterogeneity of Oxygen Distribution in Exercising Skeletal Muscle
    Gang Liu, Feilim Mac Gabhann, Aleksander S. Popel · 2012 · PLoS ONE
  169. Light and electron microscopic identification of nerve terminal sprouting and retraction in normal adult frog muscle.
    Archinto P. Anzil, Armin Bieser, Anton Wernig · 1984 · The Journal of Physiology
  170. Ultrastructure of motor end-plates during pharmacologically-induced degeneration and subsequent regeneration of skeletal muscle
    Isa Jirmanov� · 1975 · Journal of Neurocytology
  171. Reduced exercise capacity in senescent beagles: an evaluation of the periphery
    George C. Haidet, Dora Beth Parsons · 1991 · American Journal of Physiology-Heart and Circulatory Physiology
  172. Two functionally distinct myosin heavy chain isoforms in slow skeletal muscle fibres
    Stefan Galler, Karlheinz Hilber, Bärbel Gohlsch · 1997 · FEBS Letters
  173. Maximum rate of oxygen consumption related to succinate dehydrogenase activity in skeletal muscle fibres of chronic heart failure patients and controls
    Martijn A. Bekedam, Brechje J. van Beek-Harmsen, Anco Boonstra, Willem van Mechelen, Frans C. Visser, Willem J. van der Laarse · 2003 · Clinical Physiology and Functional Imaging
  174. Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men
    Lasse Gliemann, Jesper Olesen, Rasmus Sjørup Biensø, Jakob Friis Schmidt, Thorbjorn C. A. Akerstrom, Michael Nyberg, Anna Lindqvist, Jens Bangsbo, Ylva Hellsten · 2014 · American Journal of Physiology-Heart and Circulatory Physiology
  175. Discovery, mechanisms of action and safety of ibuprofen.
    Kim Drummond Rainsford · 2003 · PubMed
  176. Myosin heavy chain isoform transition in ageing fast and slow muscles of the rat
    Takahiro Sugiura, Hideki Matoba, Hirofumi Miyata, Y. KAWAI, Naotoshi Murakami · 1992 · Acta Physiologica Scandinavica
  177. Influence of electrical stimulation on a fast-twitch muscle in aging rats
    James Walters, Hugh Lee Sweeney, R. P. Farrar · 1991 · Journal of Applied Physiology
  178. Nonsteroidal Anti-Inflammatory Drug (NSAID) Use and Sarcopenia in Older People: Results From the ilSIRENTE Study
    Landi, Francesco, Marzetti, Emanuele, Liperoti, Rosa, Pahor, Marco, Russo, Andrea, Martone, Anna Maria, Colloca, Giuseppe, Capoluongo, Ettore, Bernabei, Roberto · 2013 · Journal of the American Medical Directors Association
  179. Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model
    Paturi, Satyanarayana, Gutta, Anil K., Katta, Anjaiah, Kakarla, Sunil K., Arvapalli, Ravi K., Gadde, Murali K., Nalabotu, Siva K., Rice, Kevin M., Wu, Miaozong, Blough, Eric · 2010 · Mechanisms of Ageing and Development
  180. Non-enzymatic glycosylation of myosin: effects of diabetes and ageing.
    I Syrový, Zdeněk Hodný · 1992 · PubMed
  181. New neuromuscular symptoms after old polio ("the post-polio syndrome"): clinical studies and pathogenetic mechanisms.
    Suthat Fucharoen, Pattanee Winichagoon, Pensri Pootrakul · 1987 · PubMed
  182. The Scientific Quest for Lasting Youth: Prospects for Curing Aging
    João Pedro de Magalhães · 2014 · Rejuvenation Research
  183. A physiological level of clenbuterol does not prevent atrophy or loss of force in skeletal muscle of old rats
    Kuangjen D. Chen, Stephen E. Alway · 2000 · Journal of Applied Physiology
  184. Actomyosin interactions in a novel single muscle fiber in vitro motility assay.
    Peter Höök, Lars Larsson · 2000 · Journal of Muscle Research and Cell Motility
  185. Age differences in the morphology of posterior tibial nerves of mice
    T. Samorajski · 1974 · The Journal of Comparative Neurology
  186. Mitochondrial DNA copy number threshold in mtDNA depletion myopathy
    Steve E. Durham, E. Bonilla, David C. Samuels, Salvatore DiMauro, Patrick Francis Chinnery · 2005 · Neurology
  187. Metabolic and fiber size properties of cat tibialis anterior motor units
    Thomas P. Martin, Sue C. Bodine, Roland R. Roy · 1988 · American Journal of Physiology-Cell Physiology
  188. Primary coenzyme Q10 deficiency presenting as fatal neonatal multiorgan failure
    María Andrea Desbats, Annalisa Vetro, Ivan Limongelli et al. · 2015 · European Journal of Human Genetics
  189. Molecules Involved in the Crosstalk Between Immune- and Peripheral Nerve Schwann Cells
    Nevena Tzekova, André Heinen, Patrick Küry · 2014 · Journal of Clinical Immunology
  190. Cytoplasm-to-myonucleus ratios in plantaris and soleus muscle fibres following hindlimb suspension
    Christine E. Kasper, Lin Xun · 1996 · Journal of Muscle Research and Cell Motility
  191. Mitochondrial Aging and Physical Decline: Insights From Three Generations of Women
    Sadie L. Hebert, Perrine Marquet, Ian R. Lanza, SHELLY K. MCCRADY-SPITZER, James A. Levine, Sumit Middha, Rickey E. Carter, Katherine A. Klaus, Terry M. Therneau, Edward W. Highsmith et al. · 2015 · The Journals of Gerontology Series A
  192. Studies on isolated human skeletal muscle fibersIncluding a proposed pattern of nuclear distribution and a concept of nuclear territories
    B H Landing, L DIXON, T WELLS · 1974 · Human Pathology
  193. Force-generating capacity of human myosin isoforms extracted from single muscle fibre segments
    Meishan Li, Lars Larsson · 2010 · The Journal of Physiology
  194. Nitric oxide and voluntary exercise together promote quadriceps hypertrophy and increase vascular density in female 18-mo-old mice
    Jeff Leiter, Ritika Upadhaya, Judy E. Anderson · 2012 · American Journal of Physiology-Cell Physiology
  195. Necrosis of capillaries in denervation atrophy of human skeletal muscle
    Stirling Carpenter, George Karpati · 1982 · Muscle & Nerve
  196. Age-related changes in contractile properties and expression of myosin isoforms in single skeletal muscle cells
    Lars Larsson, Xiaopeng Li, Fushun Yu, Hans Degens · 1997 · Muscle & Nerve
  197. Activity-Dependent Plasticity of Transmitter Release from Nerve Terminals in Rat Fast and Slow Muscles
    Brian Reid, Vladimir N. Martinov, Arild Njå · 2003 · Journal of Neuroscience
  198. Nonsteroidal Anti-Inflammatory Drugs in Experimental Parkinsonian Models and Parkinsons Disease
    Masato Asanuma, Ikuko Miyazaki · 2008 · Current Pharmaceutical Design
  199. Maintenance of Heterogeneity of Capillary Spacing is Essential for Adequate Oxygenation in the Soleus Muscle of the Growing Rat
    Hans Degens, Durmus Deveci, ANGIE BOTTO‐VAN BEMDEN, Louis J. C. Hoofd, Stuart Egginton · 2006 · Microcirculation
  200. Cytochrome c oxidase-intermediate fibres: Importance in understanding the pathogenesis and treatment of mitochondrial myopathy
    Julie L. Murphy, Thiloka Erandathi Ratnaike, Ersong Shang, Gavin Falkous, Emma L. Blakely, Charlotte L. Alston, Tanja Taivassalo, Ronald G. Haller, Robert William Taylor, Douglass M. Turnbull · 2012 · Neuromuscular Disorders