The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes
Open accessAbstract
Mitochondria are essential organelles for eukaryotic homeostasis. Although these organelles possess their own DNA, the vast majority (>99%) of mitochondrial proteins are encoded in the nucleus. This situation makes systems that allow the communication between mitochondria and the nucleus a requirement not only to coordinate mitochondrial protein synthesis during biogenesis but also to communicate eventual mitochondrial malfunctions, triggering compensatory responses in the nucleus. Mitochondria-to-nucleus retrograde signaling has been described in various organisms, albeit with differences in effector pathways, molecules, and outcomes, as discussed in this review.
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Citations
Cites
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“Mitochondriato-nucleus retrograde signaling has been described in various organisms, albeit with differences in effector pathways, molecules, and outcomes, as discussed in this review.”
BackgroundInterorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae
Kirchman, P. A., Kim, S., Lai, C.-Y., & Jazwinski, S. M. (1999) · Genetics · doi:10.1093/genetics/152.1.179 · Cited by 328 · cited 1×
“The mechanisms are not entirely clear but seem to involve RAS2 [99] as well as a counteraction of negative effects that rise from the age-induced increase in the generation of extrachromosomal rDNA (ribosomal DNA) circles (ERCs) [55, 98, 100, 101].”
Background
Cited by
Mitochondrial calcium exchange in physiology and disease
Garbincius, J. F., & Elrod, J. W. (2022) · Physiological Reviews · doi:10.1152/physrev.00041.2020 · Cited by 412
MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism
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Qi, Z., Smith, K. M., Bredeweg, E. L., Bosnjak, N., Freitag, M., & Nargang, F. E. (2017) · G3 Genes|Genomes|Genetics · doi:10.1534/g3.116.035402 · Cited by 12
Metadata
- Authors
- da Cunha, F. M., Torelli, N. Q., & Kowaltowski, A. J.
- Venue
- Oxidative Medicine and Cellular Longevity
- Publisher
- Wiley
- Published
- 2015
- Volume
- 2015
- Pages
- 1-10
- ISSN
- 1942-0994 (ISSN-L)
- 1942-0900
- OpenAlex
- W2166049009
- Cited by
- 167
- References
- 16
- FWCI
- 4.89
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- da Cunha, F. M., Torelli, N. Q., & Kowaltowski, A. J. (2015). Mitochondrial Retrograde Signaling: Triggers, Pathways, and Outcomes. Oxidative Medicine and Cellular Longevity. https://doi.org/10.1155/2015/482582
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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