Diosgenin: Recent Highlights on Pharmacology and Analytical Methodology

Saponins as cytotoxic agents: a review

Podolak, I., Galanty, A., & Sobolewska, D. (2010) · Phytochemistry Reviews · doi:10.1007/s11101-010-9183-z · Cited by 718

Extraction and quantification of saponins: A review

Cheok, C. Y., Salman, H. A. K., & Sulaiman, R. (2014) · Food Research International · doi:10.1016/j.foodres.2014.01.057 · Cited by 450

Anticancer steroids: linking natural and semi-synthetic compounds

Salvador, J. A. R., Carvalho, J. F. S., Neves, M. A. C., Silvestre, S., Leitão, A. J., Silva, M. M., & Melo, M. L. S. E. (2012) · Natural Product Reports · doi:10.1039/c2np20082a · Cited by 283

Antioxidative and Hypolipidemic Effects of Diosgenin, a Steroidal Saponin of Yam (Dioscorea spp.), on High-Cholesterol Fed Rats

Son, I. S., Kim, J. H., Sohn, H. Y., Son, K. H., Kim, J., & Kwon, C.-S. (2007) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70472 · Cited by 243

Diosgenin, a Steroidal Saponin, Inhibits Migration and Invasion of Human Prostate Cancer PC-3 Cells by Reducing Matrix Metalloproteinases Expression

Chen, P.-S., Shih, Y., Huang, H.-C., & Cheng, H.-W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020164 · Cited by 225

Antifungal Activity of C-27 Steroidal Saponins

Yang, C.-R., Zhang, Y., Jacob, M. R., Khan, S. I., Zhang, Y.-J., & Li, X.-C. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.50.5.1710-1714.2006 · Cited by 221

High-performance thin layer chromatography: A powerful analytical technique in pharmaceutical drug discovery

Attimarad, M., Ahmed, K. M., Al‐Dhubiab, B. E., & Sreeharsha, N. (2011) · Pharmaceutical Methods · doi:10.4103/2229-4708.84436 · Cited by 211

Cancer Chemopreventive and Therapeutic Effects of Diosgenin, a Food Saponin

Raju, J., & Mehta, R. (2009) · Nutrition and Cancer · doi:10.1080/01635580802357352 · Cited by 210

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells

Li, F., Fernandez, P. P., Rajendran, P., Hui, K. M., & Sethi, G. (2010) · Cancer Letters · doi:10.1016/j.canlet.2009.12.003 · Cited by 207

Cancer cell signaling pathways targeted by spice-derived nutraceuticals

Sung, B., Prasad, S., Yadav, V. R., & Aggarwal, B. B. (2012) · Nutrition and Cancer · doi:10.1080/01635581.2012.630551 · Cited by 204

Complementary and Alternative Treatments for Cancer Prevention and Cure (Part 1)

Mohiuddin, A. K. (2019) · Journal of Experimental and Clinical Toxicology · doi:10.14302/issn.2641-7669.ject-19-3040 · Cited by 1

Bio-production enhancement of Natural diosgenin from Balanites Aegyptiacae by callus culture

Mohamed, S., Badawy, M., El-Desouky, M. A., & Saleh, S. S. (2021) · Egyptian Journal of Chemistry · doi:10.21608/ejchem.2021.73450.3630 · Cited by 2

Evaluating the Chemopreventive Properties of Aqueous Seed Extract of Trigonella foenum graecum Against p-Dimethylaminoazobenzene (p-DAB) Induced Carcinogenesis in Mice

Biswas, S. J., Gorain, S., Patra, M., Giri, S. K., Gope, D., Karmakar, S. R., & Saha, N. C. (2021) · Springer eBooks · doi:10.1007/978-981-16-1197-1_20 · Cited by 2

Exploring the Medicinally Important Scondary Metabolites Landscape Through the Lens of Transcriptome Data in Fenugreek (Trigonella Foenum Graecum L.)Preprint

Naika, M. B. N., Sathyanarayanan, N., Sajeevan, R. S., Bhattacharyya, T., Ghosh, P., Iyer, M., Mahita, J., Joshi, A. G., Harini, K., Shafi, K. M., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1441723/v1 · Cited by 2

BIOAVAILABILITY PROBLEMS OF PHYTOSTEROLS: A SYSTEMATIC REVIEW

Jamal Basha, D., KUMAR, P. R., & Ranganayakulu, D. (2022) · International Journal of Applied Pharmaceutics · doi:10.22159/ijap.2022v14i6.45734 · Cited by 1

Genetic diversity and population structure assessment of Hellenia speciosa from Indian agro-ecological regions using inter-simple sequence repeat markers

Prabhu, K. N., Rodrigues, V., Kumar, A., Kumar, M., Srivastava, S. K., Shukla, A. K., & Sundaresan, V. (2023) · Horticulture Environment and Biotechnology · doi:10.1007/s13580-022-00466-y · Cited by 1

DIOSGENIN AT THE CELLULAR LEVEL AS A CANCER REMEDIAL AGENT

Arockiam, A. J. V., Ganesan, N., & Umapathy, D. (2023) · INDIAN DRUGS · doi:10.53879/id.60.04.11812 · Cited by 1

Identification of potential therapeutic phytocompounds targeting the G-glycoprotein of Nipah Virus: an in-silico study

Islam, M. T., Ulla, S. N., Islam, S., & Ashraf, A. (2025) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2025.2458334 · Cited by 1

Diosgenin ameliorates silica‐induced tuberculosis in rats

Adu, W. A., Ativui, S., Ofori, M., Owusu, G., Danquah, C. A., & Ossei, P. P. S. (2025) · Animal Models and Experimental Medicine · doi:10.1002/ame2.70055 · Cited by 1

Pharmacotherapeutic importance of phytoconstituents in the management of Polycystic Ovary Syndrome (PCOS) and associated complications

Chaudhary, V., Haloi, P., Munjal, K., & Chitme, H. R. (2025) · Egyptian Journal of Basic and Applied Sciences · doi:10.1080/2314808x.2025.2554517 · Cited by 4

Therapeutic potential of diosgenin in hepatocellular carcinoma through molecular mechanisms and nanodelivery strategies

Jyotishi, C., Patel, M., Prajapati, S., & Gupta, R. (2026) · Discover Oncology · doi:10.1007/s12672-026-04399-1 · Cited by 1

Oleamide Mediates the Anti‐Inflammatory Potential of Smilax wightii A. DC. through Regulation of LOX and COX Gene Expression in Arachidonic Acid Pathway

Anand, A. V., & Sukumaran, S. T. (2026) · New Zealand Journal of Botany · doi:10.1002/nzb2.70037 · Cited by 1

Diosgenin prevents alcohol-induced intensification of seizures, psychiatric comorbidities, and their neuropathological consequences in kindled epileptic mice

Ben-Azu, B., Chidebe, E. O., Chijioke, B. S., Esuku, D. T., Oritsemuelebi, B., Onuelu, J. E., Iwhiwhu, P., Oyovwi, O. M., Emudainohwo, J. O. T., Uruaka, C. I., et al. (2026) · Neuroscience · doi:10.1016/j.neuroscience.2026.02.015 · Cited by 1

Immunomodulatory and locomotor regulations via Diosgenin treatment in lipopolysaccharide-induced chronic fatigue syndrome (CFS)/ depressive despair symptom: an in vivo assessment

Shirole, R. L., Khalane, M. R., Nage, V. P., Shirole, N. L., Chawre, S. V., Alsayari, A., Wahab, S., Bhunia, A., & Patil, D. K. (2026) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-026-05263-3 · Cited by 1

Alternative Treatments for Cancer Prevention and Cure [Part 1]

Mohiuddin, A. K. (2019) · Advances in Pharmacology & Clinical Trials · doi:10.23880/apct-16000168 · Cited by 1

Evaluation of Some Phytogenic Feed Supplements for Lean Meat Production in Commercial Broiler Chicken

Mallika, E. N., Kumari, K. N. R., Sudheer, K., Sunidhi, Ravikanth, K., & Ganguly, B. (2020) · Current Journal of Applied Science and Technology · doi:10.9734/cjast/2020/v39i3231011 · Cited by 1

Can Spices Cure Flu?: A Multiple targets based Bioinformatics analysis

Chaturvedi, P., Saxena, V. L., Raina, V., Solanki, P. S., & Chaturvedi, A. (2022) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2022.00820 · Cited by 1

Dioscorea

Haider, M. Z., Shaheen, A., Mahmood, S., Tariq, A., Rafique, H., & Gohar, U. F. (2023) · Springer eBooks · doi:10.1007/978-3-031-35403-8_46 · Cited by 1

Tribulus terrestris L. - a review

Neumann, J., Líbalová, K. Š., Konvalina, P., Smetana, P., Vráblík, P., & Šoch, M. (2024) · Journal of Central European Agriculture · doi:10.5513/jcea01/25.1.4119 · Cited by 1

The Anticancer Poperties of Diosgenin on Colorectal Cancer Cells Induced by Wnt/Β Catenin Signaling Pathway

Abdolmaleki, A., Rezazadeh, D., Zhaleh, M., Nemati, H., Ghobadi, H., & Hemmatabadi, F. K. (2024) · Journal of Clinical Research in Paramedical Sciences · doi:10.5812/jcrps-149338 · Cited by 1

Development and Validation of High-Performance Thin Layer Chromatography Method for Simultaneous Estimation of Catechin, Bergenin and Diosgenin in Varunadi Kvatha Churna

Chitte, K. M., Prajapati, D., Dodiya, T. R., & Patel, J. (2024) · Journal of Natural Remedies · doi:10.18311/jnr/2024/43889 · Cited by 1

Diosgenin Biosynthesis in the Sprouts of Fenugreek as Influenced by Chitosan

Kwon, D. Y., Kim, J. K., & Park, S. U. (2019) · OnLine Journal of Biological Sciences · doi:10.3844/ojbsci.2019.104.109 · Cited by 1

Siddha Medicine Combat Against Novel Corona Virus – An Appraisal.

Jenefa Rose Priya., T. (2020) · Journal of Emerging Technologies and Innovative Research · Cited by 1

Complementary and Alternative Treatments for Cancer Prevention and Cure [Part 1]

Mohiuddin, A. K. (2019) · Cancer Research and Cellular Therapeutics · doi:10.31579/2640-1053/058 · Cited by 1

GAS CHROMATOGRAPHIC-MASS SPECTROMETRIC ANALYSIS OF K.G. 101 (KSHEERAGULOOCHI 101): AN AYURVEDIC PATENT PRODUCT

Meenu, M., & Narayanan, S. (2023) · International Journal of Research in Ayurveda and Pharmacy · doi:10.7897/2277-4343.140238 · Cited by 1

Enrichment of hydroalcoholic extract of Trigonella foenum-graecum L. seed with major components using TLC fingerprint, image analysis, and design of experiment studies

Dahiya, J., Mangal, A. K., Bolleddu, R., Dutta, S., Kharwar, S., Hazra, K., & Prasad, P. V. V. (2022) · Journal of Drug Research in Ayurvedic Sciences · doi:10.4103/jdras.jdras_20_22 · Cited by 1

Enhanced in vitro production of diosgenin in shoot cultures of Dioscorea deltoidea by elicitation and precursor feedingPreprint

Nazir, R., Gupta, S., Kumar, V., Gupta, A. P., Dwivedi, P., Dey, A., Malik, T., & Pandey, D. K. (2020) · Research Square · doi:10.21203/rs.3.rs-41829/v2 · Cited by 1

Plant‐based Nutraceuticals with Anticarcinogenic Potential

Al‐Odat, O. S., Yao, G., Schmalbach, N. K., Guirguis, D. A., Aloudat, O., Newport‐Ratiu, P. A., Jonnalagadda, S. C., & Pandey, M. K. (2024) · Wiley eBooks · doi:10.1002/9781394241576.ch8 · Cited by 1

138 思いやりの精神構造とその発達過程(第19報) : 思いやりが育つ保育(7)

長山, 篤., 青木, 泰., 秋山, 光., 篠木, 理., 永田, 陽., 平井, 信., 帆足, 暁., 帆足, 英., 千羽, 喜., & 中川, 英. (2002) · 日本保育学会大会発表論文集

Biotechnological Strategies for Improvement of Aromatic and Medicinal Herbs

Jan, S., & Abbas, N. (2018) · Elsevier eBooks · doi:10.1016/b978-0-08-102227-6.00005-x

Development and Validation of Sensitive HPLC-UV-DAD Method for Determination of Diosgenin in Plants of Species of Dioscorea Genus

da Silva, L. R. G., Cheibub, A. M. D. S. S., Valverde, A. L., & Netto, A. D. P. (2019) · Revista Virtual de Química · doi:10.21577/1984-6835.20190090

El potencial de la diosgenina en el área médica

Lara, D. F. M., Sancho, G. B. V., & Martínez, Y. E. C. (2020) · RD-ICUAP · doi:10.32399/icuap.rdic.2448-5829.2020.18.244

Analysis of Genotypic Variation and Selection of Superior Genotypes of Balanites roxburghii Planch. from South IndiaPreprint

Yadav, G. G., & Murthy, H. N. (2021) · Research Square · doi:10.21203/rs.3.rs-793589/v1

Identification of Novel Protein Targets for Fenugreek to Treat Diabetes: A Molecular Docking Study

Nandyala, H., Pham, A., Wagle, A., Daggolu, H., Guha, A., Sankar, R., Chan, C., Venkatesh, D., & Renganathan, G. (2021) · Journal of Student Research · doi:10.47611/jsrhs.v10i3.1739

038 思いやりの精神構造とその発達過程(第15報) : 思いやりが育つ保育(3)

長山, 篤., 青木, 泰., 秋山, 光., 田島, 昌., 千羽, 喜., 中川, 英., 永田, 陽., 平井, 信., 帆足, 暁., & 帆足, 英. (1998) · 日本保育学会大会研究論文集

Fenugreek (Trigonella foenum-graecum L.): A Palatable Spice, An Active Herb, A Promising Functional Food, and Even More

(2022) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9781681089492122020009

A Few More and Recently Reported Herbs

Anastassakis, K. (2022) · Springer eBooks · doi:10.1007/978-3-031-08057-9_61

The in vitro and in silico Anticholinesterase Ac-tivities of Brittle Star (Ophiocoma erinaceus) crude venoms from the Persian Gulf-Bushehr

Dehghani, H., Rashedinia, M., Mohebbi, G. H., Vazirizadeh, A., Maryamabadi, A., & Barmak, A. R. (2022) · Iranian South Medical Journal · doi:10.52547/ismj.25.4.297

Steroidal Saponin Isolated from Dioscorea alata L. Extract Improve Digestive Tract Allergy in Balb/C Mice Induced by Ovalbumin

Makiyah, S. N. N., Tasminatun, S., Djati, M. S., Rifa’i, M., & Widodo, W. (2023) · INDONESIAN JOURNAL OF PHARMACY · doi:10.22146/ijp.4614

SUTIKA WELLBEING WSR TO INVOLUTION OF UTERUS- A PILOT STUDY

(2023) · International Journal of Biology Pharmacy and Allied Sciences · doi:10.31032/ijbpas/2023/12.6.1037

Can Antidiabetic Plants Used in Cameroon Play as Key for the Treatment of Childhood, Adolescent and Adult Obesity?

Tsabang, N. (2021) · Interventions in Obesity & Diabetes · doi:10.31031/iod.2021.05.000612

Bioactive Compounds and Biological Activities of Nepal Yam (Dioscorea deltoidea wall. Ex Griseb.)

Sati, P., Trivedi, V. L., Semwal, P., & Nautiyal, M. C. (2023) · Reference series in phytochemistry · doi:10.1007/978-3-031-29006-0_38-1

Phytochemical Profiles and Biological Studies of Selected Botanical Dietary Supplements Used in the United States

Arellano, E. D. S., Castro-Dionicio, I. Y., Jeyaraj, J. G., Ezzone, N. P. M., & de Blanco, E. J. C. (2023) · Fortschritte der Chemie Organischer Naturstoffe/Fortschritte der Chemie organischer Naturstoffe/Progress in the chemistry of organic natural products · doi:10.1007/978-3-031-26768-0_1

Kanser Tedavisinde Kullanılan Tıbbi Bitkiler

AKÇA, B., & Güven, L. (2023) · doi:10.59287/sbocc.296

Designing Dioscorea Genomes for Improved Nutritional and Pharmaceutical Properties

Bhattacharjee, R. (2023) · Springer eBooks · doi:10.1007/978-981-19-3627-2_60-1

Preliminary screening of Pioglitazone and Diosgenin novel combination for Alzheimer's disease

Mohammed, S., Nandhyala, A., Rao, G. N., Rajagopal, K., Palathoti, N., & Antony, J. (2023) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2023.134926

Synergistic Effects of Momordica Charantia, Nigella Sativa, and Anethum Graveolens on Metabolic Syndrome Targets: In Vitro Enzyme Inhibition and in Silico AnalysesPreprint

Chavan, R. S., Khatib, N. A., Hariprasad, M. G., Patil, V. S., & Redhwan, M. A. M. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4607158

Extraction and Isolation of Tyrosine Ammonia Lyase (TAL) and Diosgenin from Persea americana as Potent Inhibitors of Melanin Synthesis Involving In Vivo Study on Zebrafish Embryos

Umaima, S. U., Singh, K., & Veeraraghavan, V. P. (2023) · Journal of Natural Remedies · doi:10.18311/jnr/2023/33021

Bioactive Compounds and Biological Activities of Edible Yam (Dioscorea sp.) in Thailand

Hongsprabhas, P., Srivichai, S., Israkarn, K., & Sakuanrungsirikul, S. (2023) · Reference series in phytochemistry · doi:10.1007/978-3-031-29006-0_39-1

Oligopeptidase B of Dioscorea Opposita “Nagaimo”: Isolation, Biochemical Characterization, and Primary StructurePreprint

Miyazaki, S., Sakaue, T., Yamane, T., Suzuki, J., Higashiyama, S., & Ohkubo, I. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4658480

Designing Dioscorea Genomes for Improved Nutritional and Pharmaceutical Properties

Bhattacharjee, R. (2023) · Springer eBooks · doi:10.1007/978-981-19-4169-6_60

In-vitro and in-silico investigation of α-amylase and α-glucosidase inhibition using Chamaecostus cuspidatus leaf for diabetes mellitusPreprint

Balaji, M. P., & Rajeswari, V. D. (2024) · Research Square · doi:10.21203/rs.3.rs-3990166/v1

A sustainable approach towards extraction of Diosgenin from fenugreek seeds using Polystyrene/Divinyl Benzene Resin

Kumar, S., M, P. B., & Sudhakara, A. (2024) · Journal of Pharmacognosy and Phytochemistry · doi:10.22271/phyto.2024.v13.i2f.14925

Hydrogen Bond Regulation to Promote the Direct Production of Diosgenin from Dioscorea Zingiberensis RhizomesPreprint

Lü, F., Niu, Y., Zhang, X., Yu, W., Yin, H., Lu, R., & Liu, Z.-G. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.4821272

Isolation and structure elucidation of biological active compounds from Euphorbia deightonii and Centrapalus pauciflorus

Saidu, M. B. (2023) · doi:10.14232/phd.11777

Bioactive Compounds and Biological Activities of Nepal Yam (Dioscorea deltoidea wall. Ex Griseb.)

Sati, P., Trivedi, V. L., Semwal, P., & Nautiyal, M. C. (2024) · Reference series in phytochemistry · doi:10.1007/978-3-031-44746-4_38

Bioactive Compounds and Biological Activities of Edible Yam (Dioscorea sp.) in Thailand

Hongsprabhas, P., Srivichai, S., Israkarn, K., & Sakuanrungsirikul, S. (2024) · Reference series in phytochemistry · doi:10.1007/978-3-031-44746-4_39

The Benefits of Uwi Plant (Dioscorea alata L.) for Health: Knowledge, Attitude, and Its Distribution in Daerah Istimewa Yogyakarta

Makiyah, S. N. N., Kamal, M., Kita, M., & Aini, L. N. (2024) · E3S Web of Conferences · doi:10.1051/e3sconf/202459504006

Exploration of Potential Therapeutic Targets of Diosgenin in Pulmonary Fibrosis through Network Pharmacology and Mendelian RandomizationPreprint

徐, 文., 黄, 文., Xin, G., & 潘, 文. (2024) · Research Square · doi:10.21203/rs.3.rs-5661693/v1

Dioscorea dumetorum (bitter yam) tuber induces the apoptosis of liver cancer cells

Victory, P. C., Waziri, P. M., Auta, R., Tyoapine, D., Tahir, M. I., & Ahmad, A. E.-F. (2025) · World Academy of Sciences Journal · doi:10.3892/wasj.2025.325

Isolation, biochemical characterization, and primary structure and active site determination of Dioscorea opposita (‘Nagaimo’) oligopeptidase B

Miyazaki-Katamura, S., Chosei, M., Tate, S., Sakaue, T., Yamane, T., Suzuki, J., Higashiyama, S., & Ohkubo, I. (2025) · Biochemistry and Biophysics Reports · doi:10.1016/j.bbrep.2025.102071

Novel Granular Formulation of Solanum nigrum and Cichorium intybus Leaf Juice Hepatoprotective Effects Against Paracetamol-induced Toxicity in Rats

Khatoon, S., Rahman, K., Sultana, A., & Fakeha-firdous, K. (2025) · Current Drug Therapy · doi:10.2174/0115748855399874250726091823

Phytochemical Constituents, Proximate Composition and Antibacterial Activity of Ethanol Extract of Costus Afer (Monkey Sugar Cane) on Escherichia Coli and Klebsiella PneumoniaePreprint

Oghenekparobor, M. C. (2025) · Research Square · doi:10.21203/rs.3.rs-7843092/v1

Phytochemical Constituents, Proximate Composition and Antibacterial Activity of Ethanol Extract of Costus Afer (Monkey Sugar Cane) on Escherichia Coli and Klebsiella PneumoniaePreprint

Oghenekparobor, M. C. (2025) · Research Square · doi:10.21203/rs.3.rs-7843092/v2

Diosgenin Enhances the Sensitivity to Methotrexate Through Oxidative DNA Damage in Saos-2 Osteosarcoma Cancer Cells

Ghobadi, H., Valizadeh, A., Dashti, M., Ghasemzadeh, A., & Yousefi, B. (2025) · Drug Research · doi:10.1055/a-2713-0136

Targeted Ultra‐High Performance Liquid Chromatography–Electrospray Ionization Triple Quadrupole Mass Spectrometry‐Based Quantification of Diosgenin in Hellenia speciosa for Its Wild Populations Screening: A Quality Control Assessment

Singh, P., Samanthula, G., Chandana, J. M., Ramchandran, R. K., Kodam, C., Suraj, Neelu, S., & Bhаdoriyа, K. (2025) · Separation Science Plus · doi:10.1002/sscp.70167

Inhibitory Effects of Diosgenin on Breast Cancer Cell Progression through Regulation of Metastatic Gene Expression

Montazer, M., Jangi, E., Molavand, M., Yousefi, B., & Valizadeh, A. (2025) · International Journal of Drug Research in Clinics · doi:10.34172/ijdrc.2025.e20

Formulation and Evaluation of Diosgenin Solid Dispersion Gel for Wound Healing

Salunke, M. R., Wabale, D., Aher, S., & Mathure, D. M. (2026) · Journal of Pharmaceutical Innovation · doi:10.1007/s12247-026-10769-7

Therapeutic potential of herbal medicines in management of psoriasis: A comprehensive review

Devi, N. V., Prabhu, P. P., Nair, A., Mulukuri, N. V. L. S., & Chaudhary, S. K. (2026) · South African Journal of Botany · doi:10.1016/j.sajb.2026.06.009

Acute and Chronic Toxicity Assessment of Diosgenin Polyethylene Glycol Succinate in Wistar Rats: Safety Evaluation of a Novel Universal Solubilizer

Velmurugan, V., Shanmugham, V., & Arumugam, T. (2026) · International Journal of Toxicology · doi:10.1177/10915818261469132

Nature’s estrogen: Dioscorea and the emerging potential of β-selective estrogen receptor modulation in menopause

Halder, S., Pal, D., Biswas, A. S., Goswami, S., Hazra, S., Barık, V., Banerjee, S., Mandal, A., Sharma, S., & Naskar, S. (2026) · Food and Humanity · doi:10.1016/j.foohum.2026.101449

Preclinical advances on diosgenin-loaded nanomedicines

Matias, M., Martins, A. S., & Silvestre, S. (2026) · Nanomedicine · doi:10.1080/17435889.2026.2734068

Diosgenin Alleviates Neuropathic Pain Associated with Alterations in Spinal Mitochondrial and ER Stress-Related Factors in CCI Mice

Rahman, M. M., 윤태수, Yum, S. H., Shim, Y. W., Jo, Y. Y., & Park, C. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27198624

Development and Validation of Sensitive HPLC-UV-DAD Method for Determination of Diosgenin in Plants of Species of Dioscorea Genus

da Silva, L. R. G., Cheibub, A. M. D. S. S., Valverde, A. L., & Netto, A. D. P. (2019) · Revista Virtual de Química · doi:10.21577/1984-6835.20190090

DIOSGENIN: AN INTEGRATED REVIEW OF CHEMICAL RESEARCH, ANALYTICAL TECHNIQUES, AI APPLICATIONS, AND SAFETY: A Comprehensive Review

Meghana, D., Bhavana, A., Kasthuri, B., Nikhila, A., Yaswanth, A., Chowdary, D. Y. A., & Madhuri, M. V. B. (2026) · Zenodo (CERN European Organization for Nuclear Research) · doi:10.5281/zenodo.23011253

Estimation of Diosgenin by HPLC in a Dioscorea zingiberensis Collection from Different Local Markets in Middle and South Iraq

Al-Yassiry, Z. A. N., Jebor, M. A., & Al-Alwani, B. (2024) · International Journal of Scientific Research in Biological Sciences

Development and Validation of an HPLC Method for Diosgenin, A Bioactive Compound in the Rhizomes of Chamaecostus cuspidatus

Saliya, H., Madam, J., Patel, H. D., Lakhani, M., Patel, V., Shah, L., Vyas, V., & Shah, M. B. (2025) · Pharmacognosy Research · doi:10.5530/pres.20252199 · Cited by 1

Method Development for Quantitative Determination of Diosgenin from the Seeds of Fenugreek, Trigonella foenum-graecum L.

Sukhanov, A. E., Ставрианиди, А. Н., Кубасова, Е. Д., Panasyuk, A. S., & Buyuklinskaya, O. V. (2020) · Drug development & registration · doi:10.33380/2305-2066-2020-9-3-150-156