The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Oxidative Stress and Inflammation: What Polyphenols Can Do for Us?
Open accessAbstract
Oxidative stress is viewed as an imbalance between the production of reactive oxygen species (ROS) and their elimination by protective mechanisms, which can lead to chronic inflammation. Oxidative stress can activate a variety of transcription factors, which lead to the differential expression of some genes involved in inflammatory pathways. The inflammation triggered by oxidative stress is the cause of many chronic diseases. Polyphenols have been proposed to be useful as adjuvant therapy for their potential anti‐inflammatory effect, associated with antioxidant activity, and inhibition of enzymes involved in the production of eicosanoids. This review aims at exploring the properties of polyphenols in anti‐inflammation and oxidation and the mechanisms of polyphenols inhibiting molecular signaling pathways which are activated by oxidative stress, as well as the possible roles of polyphenols in inflammation‐mediated chronic disorders. Such data can be helpful for the development of future antioxidant therapeutics and new anti‐inflammatory drugs.
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Cites
Polyphenols: Food sources and bioavailability
Manach, C., Scalbert, A., Morand, C., Rémésy, C., & Jiménez, L. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.727 · Cited by 8,175
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Lindsay, J. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf074 · Cited by 1,261
Vascular effects of cocoa rich in flavan-3-ols
Heiss, C. (2003) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.290.8.1030 · Cited by 425 · cited 1×
“The mechanism of polyphenols on vascular function depends on the ability of nitric oxide synthase (eNOS) and its bioavailability to the endothelium [67, 68].”
BackgroundKim, J. M., Lee, E. K., Kim, D. H., Yu, B. P., & Chung, H. Y. (2010) · AGE · doi:10.1007/s11357-009-9124-1 · Cited by 133
Cited by
Sharifi-Rad, M., Anil Kumar, N. V., Zucca, P., Varoni, E. M., Dini, L., Panzarini, E., Rajkovic, J., Tsouh Fokou, P. V., Azzini, E., Peluso, I., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00694 · Cited by 1,971
The Role of the Plant Antioxidant System in Drought Tolerance
Laxa, M., Liebthal, M., Telman, W., Chibani, K., & Dietz, K.-J. (2019) · Antioxidants · doi:10.3390/antiox8040094 · Cited by 855
Microalgae for High-Value Products Towards Human Health and Nutrition
Barkia, I., Saari, N., & Manning, S. R. (2019) · Marine Drugs · doi:10.3390/md17050304 · Cited by 719
Mediterranean diet nutrients to turn the tide against insulin resistance and related diseases
Mirabelli, M., Chiefari, E., Arcidiacono, B., Corigliano, D. M., Brunetti, F. S., Maggisano, V., Russo, D., Foti, D. P., & Brunetti, A. (2020) · Nutrients · doi:10.3390/nu12041066 · Cited by 272
Grosso, G., Laudisio, D., Frias-Toral, E., Barrea, L., Muscogiuri, G., Savastano, S., & Colao, A. (2022) · Nutrients · doi:10.3390/nu14061137 · Cited by 255
Metadata
- Authors
- Hussain, T., Tan, B., Yin, Y., Blachier, F., Tossou, M. C. B., & Rahu, N.
- Venue
- Oxidative Medicine and Cellular Longevity
- Publisher
- Wiley
- Published
- 2016-01
- Volume
- 2016
- Issue
- 1
- Pages
- 7432797-7432797
- ISSN
- 1942-0994 (ISSN-L)
- 1942-0900
- OpenAlex
- W2521574223
- Cited by
- 2,082
- References
- 5
- FWCI
- 41.40
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
