The DOI matches its Crossref record; 128 of the 128 references it cites were found in a registry or an index.
The Role of Oxidative Stress and Antioxidant Balance in Pregnancy
Open accessAbstract
It has been widely known that oxidative stress disrupts the balance between reactive oxygen species (ROS) and the antioxidant system in the body. During pregnancy, the physiological generation of ROS is involved in a variety of developmental processes ranging from oocyte maturation to luteolysis and embryo implantation. While abnormal overproduction of ROS disrupts these processes resulting in reproductive failure. In addition, excessive oxidative stress impairs maternal and placental functions and eventually results in fetal loss, IUGR, and gestational diabetes mellitus. Although some oxidative stress is inevitable during pregnancy, a balancing act between oxidant and antioxidant production is necessary at different stages of the pregnancy. The review aims to highlight the importance of maintaining oxidative and antioxidant balance throughout pregnancy. Furthermore, we highlight the role of oxidative stress in pregnancy‐related diseases.
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Cites
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Cited by
Collins, E. J., Bowyer, C., Tsouza, A., & Chopra, M. (2022) · Biology · doi:10.3390/biology11020239 · Cited by 293
Chatzakis, C., Sotiriadis, A., Fatouros, I. G., Jamurtas, A. Z., Deli, C. K., Papagianni, M., Dinas, K., & Mastorakos, G. (2022) · Diagnostics · doi:10.3390/diagnostics12071732 · Cited by 17
Marinello, W. P., Gillera, S. E. A., Han, Y., Richardson, J. R., St Armour, G., Horman, B. M., & Patisaul, H. B. (2023) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2023.112041 · Cited by 6
Metadata
- Authors
- Hussain, T., Murtaza, G., Metwally, E., Kalhoro, D. H., Kalhoro, M. S., Rahu, B. A., Sahito, R. G. A., Yin, Y., Yang, H., Chughtai, M. I., & Tan, B.
- Venue
- Mediators of Inflammation
- Publisher
- Wiley
- Published
- 2021-01
- Volume
- 2021
- Issue
- 1
- Pages
- 9962860-9962860
- ISSN
- 0962-9351 (ISSN-L)
- 1466-1861
- OpenAlex
- W3203104501
- Cited by
- 265
- References
- 128
- FWCI
- 29.56
- Type
- journal article
- Language
- en
- Open access
- gold
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- Hussain, T., Murtaza, G., Metwally, E., Kalhoro, D. H., Kalhoro, M. S., Rahu, B. A., Sahito, R. G. A., Yin, Y., Yang, H., Chughtai, M. I., & Tan, B. (2021). The Role of Oxidative Stress and Antioxidant Balance in Pregnancy. Mediators of Inflammation. https://doi.org/10.1155/2021/9962860
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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