The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Intracortical Mechanisms of Mismatch Negativity Dysfunction in Schizophrenia
Abstract
Event-related potentials provide an objective index of neurocognitive dysfunction in schizophrenia. Schizophrenia subjects show a decreased mismatch negativity (MMN) amplitude relative to age- and sex-matched controls, along with a characteristic pattern of MMN dysfunction across conditions. Deficits in MMN generation are accompanied by (1) impaired precision of auditory sensory memory performance and (2) an interstimulus-interval-dependent deficit in auditory N 1 generation. Similar deficits are observed following systemic or local infusion of N-methyl-D-aspartate (NMDA) antagonists, supporting glutamatergic and phencyclidine/NMDA models of the disorder. Deficits in MMN generation may also be seen following focal cortical damage, especially to the dorsolateral prefrontal cortex. MMN thus provides a useful tool for investigating mechanisms underlying brain dysfunction in schizophrenia.
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Cites
Recent advances in the phencyclidine model of schizophrenia
(1991) · American Journal of Psychiatry · doi:10.1176/ajp.148.10.1301 · Cited by 2,904
Self-citationThe Glutamatergic Dysfunction Hypothesis for Schizophrenia
Coyle, J. T. (1996) · Harvard Review of Psychiatry · doi:10.3109/10673229609017192 · Cited by 568
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Self-citationERPs in schizophrenia: Effects of antipsychotic medication
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Automatic auditory discrimination is impaired in Parkinson’s disease
Pekkonen, E., Jousmäki, V., Reinikainen, K., & Partanen, J. (1995) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(94)00304-4 · Cited by 96
Kreitschmann-Andermahr, I., Rosburg, T., Meier, T., Volz, H.-P., Nowak, H., & Sauer, H. (1999) · Schizophrenia Research · doi:10.1016/s0920-9964(98)00115-7 · Cited by 87
Cited by
Processing of low-probability sounds by cortical neurons
Ulanovsky, N., Las, L., & Nelken, I. (2003) · Nature Neuroscience · doi:10.1038/nn1032 · Cited by 1,049
Mismatch negativity in schizophrenia: a meta-analysis
Umbricht, D., & Krljes, S. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2004.12.002 · Cited by 742
The mismatch negativity (MMN): towards the optimal paradigm
Näätänen, R., Pakarinen, S., Rinne, T., & Takegata, R. (2004) · Clinical Neurophysiology · doi:10.1016/j.clinph.2003.04.001 · Cited by 721
Mismatch negativity (MMN), the deviance-elicited auditory deflection, explained
May, P. J. C., & Tiitinen, H. (2010) · Psychophysiology · doi:10.1111/j.1469-8986.2009.00856.x · Cited by 549
When Doors of Perception Close: Bottom-up Models of Disrupted Cognition in Schizophrenia
Javitt, D. C. (2009) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.032408.153502 · Cited by 503
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Metadata
- Authors
- Javitt, D. C.
- Venue
- Audiology and Neurotology
- Publisher
- S. Karger AG
- Published
- 2000
- Volume
- 5
- Issue
- 3-4
- Pages
- 207-215
- ISSN
- 1420-3030 (ISSN-L)
- 1421-9700
- OpenAlex
- W1981359380
- Cited by
- 161
- References
- 6
- FWCI
- 4.23
- Type
- journal article
- Language
- en
- Open access
- closed
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