The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Specificity of Cognitive Deficits in Bipolar Disorder versus Schizophrenia
Abstract
Background: More and more epidemiological, genetic and neuroimaging studies show similarities between bipolar disorder (BD) and schizophrenia (SZ). Cognitive functions are known to be highly impaired in SZ and are increasingly studied in BD. When both populations are compared, the conclusions appear to be contradictory. The purpose of this review is to help define the profile of cognitive deficits in BD and in SZ. Methods: A systematic review of the literature of neuropsychological studies comparing BD and SZ was made, beginning in January 1990 and ending in January 2005. Thirty-eight studies met the required quality criteria and were included in this review. Results: Bipolar patients exhibit extensive cognitive abnormalities with a pattern of deficits that is not unique to this disease. However, when compared to schizophrenic patients, bipolar patients demonstrate a lesser degree of deficits, particularly concerning premorbid and current intelligence quotient and perhaps attention, verbal memory and executive functions. When looking into effect sizes, there seem to be different profiles even in studies finding no significant differences. Conclusions: The neuropsychological differences reported between both groups could be due to the presence of psychotic features, to environmental factors (stressful events, duration of the disease and number of hospitalisations) and could also be related to differences during the neurodevelopmental phase. Further studies should confirm whether these results are truly related to different neurobiological backgrounds.
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Cites
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What are the functional consequences of neurocognitive deficits in schizophrenia?
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Clinical and Neurobiological Effects of Tianeptine and Paroxetine in Major Depression
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Cited by
Logue, S. F., & Gould, T. J. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.08.007 · Cited by 477
Functioning and Disability in Bipolar Disorder: An Extensive Review
Sanchez-Moreno, J., Martinez-Aran, A., Tabarés-Seisdedos, R., Torrent, C., Vieta, E., & Ayuso-Mateos, J. L. (2009) · Psychotherapy and Psychosomatics · doi:10.1159/000228249 · Cited by 443
Self-citationEmpirical evidence for discrete neurocognitive subgroups in bipolar disorder: clinical implications
Burdick, K. E., Russo, M., Frangou, S., Mahon, K., Braga, R. J., Shanahan, M., & Malhotra, A. K. (2014) · Psychological Medicine · doi:10.1017/s0033291714000439 · Cited by 355
Simonsen, C., Sundet, K., Vaskinn, A., Birkenaes, A. B., Engh, J. A., Faerden, A., Jonsdottir, H., Ringen, P. A., Opjordsmoen, S., Melle, I., et al. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbp034 · Cited by 310
Biomarkers and clinical staging in psychiatry
McGorry, P., Keshavan, M., Goldstone, S., Amminger, P., Allott, K., Berk, M., Lavoie, S., Pantelis, C., Yung, A., Wood, S., et al. (2014) · World Psychiatry · doi:10.1002/wps.20144 · Cited by 306
Metadata
- Authors
- Daban, C., Martinez-Aran, A., Torrent, C., Tabarés-Seisdedos, R., Balanzá-Martínez, V., Salazar-Fraile, J., Selva-Vera, G., & Vieta, E.
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2006
- Volume
- 75
- Issue
- 2
- Pages
- 72-84
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- OpenAlex
- W1966878525
- Cited by
- 207
- References
- 9
- FWCI
- 8.82
- Type
- journal article
- Language
- en
- Open access
- closed
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