Vestibular-Induced Vomiting after Vestibulocerebellar Lesions
Abstract
Vestibular stimulation, by means of sinusoidal electrical polarization of the labyrinths of decerebrate cats, can produce vomiting and related activity resembling that seen in motion sickness. The symptoms include panting, salivation, swallowing, and retching as well as vomiting. These symptoms can be produced in cats with lesions of the posterior cerebellar vermis. In contrast to a previous proposal by Wang and Chinn in 1956, we suggest that a transcerebellar pathway from the vestibular apparatus through the nodulus and uvula to the ''vomiting center'' is not essential for vestibular-induced vomiting and, by analogy, for the occurrence of many symptoms of motion sickness.
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Weech, S., Kenny, S., & Barnett-Cowan, M. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.00158 · Cited by 913 · see citing works
Motion sickness: more than nausea and vomiting
Lackner, J. R. (2014) · Experimental Brain Research · doi:10.1007/s00221-014-4008-8 · Cited by 314 · see citing works
“Miller and colleagues have identified the neural circuits controlling the respiratory and abdominal muscles during nausea and vomiting, and which brain areas are critical (Miller and Grelot 1996; Miller et al. 1990, 1994; Miller and wilson 1983).”
BackgroundPhysiological basis and pharmacology of motion sickness: an update
Yates, B. J., Miller, A. D., & Lucot, J. B. (1998) · Brain Research Bulletin · doi:10.1016/s0361-9230(98)00092-6 · Cited by 230 · see citing works
Self-citationBrainstem processing of vestibular sensory exafference: implications for motion sickness etiology
Oman, C. M., & Cullen, K. E. (2014) · Experimental Brain Research · doi:10.1007/s00221-014-3973-2 · Cited by 103 · see citing works
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Holstege, G. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63274-6.00020-5 · Cited by 102 · see citing works
Yates, B. J., Catanzaro, M. F., Miller, D. J., & McCall, A. A. (2014) · Experimental Brain Research · doi:10.1007/s00221-014-3937-6 · Cited by 90 · see citing works
The Effects of Cannabidiol and Tetrahydrocannabinol on Motion‐Induced Emesis in<i>Suncus murinus</i>
Cluny, N. L., Naylor, R. J., Whittle, B. A., & Javid, F. A. (2008) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2008.00253.x · Cited by 39 · see citing works
Arshian, M. S., Puterbaugh, S. R., Miller, D. J., Catanzaro, M. F., Hobson, C. E., McCall, A. A., & Yates, B. J. (2013) · Experimental Brain Research · doi:10.1007/s00221-013-3568-3 · Cited by 12 · see citing works
- Authors
- Miller, A. D., & Wilson, V. J.
- Affiliations
- Rockefeller University (US)
- Venue
- Brain, Behavior and Evolution
- Publisher
- S. Karger AG
- Published
- 2008-03-18
- Volume
- 23
- Issue
- 1-2
- Pages
- 26-31
- ISSN
- 0006-8977 (ISSN-L)
- 1421-9743
- OpenAlex
- W2039969157
- Cited by
- 46
- References
- 0
- Citations by year
- 2026: 1 · 2024: 1 · 2019: 2 · 2017: 1 · 2014: 5 · 2013: 1 · 2012: 2
- FWCI
- 0.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain Behavior and Evolution (publishedVersion)
- PubMed (publishedVersion)
- NASA STI Repository (National Aeronautics and Space Administration) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Health Sciences › Medicine › Surgery › Nausea and vomiting management
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Keywords
- motion sickness, vestibular stimulation, Nodulus, uvula, vomiting center, salivary secretion, retching, cats
- MeSH terms
- Animals, Brain Mapping, Cats, Cerebellum, Disease Models, Animal, Motion Sickness, Semicircular Canals, Vestibule, Labyrinth, Vomiting
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