The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Human SGBS Cells – a Unique Tool for Studies of Human Fat Cell Biology
Open accessAbstract
The human Simpson-Golabi-Behmel syndrome (SGBS) preadipocyte cell strain provides a unique and useful tool for studies of human adipocyte biology. The cells originate from an adipose tissue specimen of a patient with SGBS. They are neither transformed nor immortalized, and provide an almost unlimited source due to their ability to proliferate for up to 50 generations with retained capacity for adipogenic differentiation. So far, the cells have been used for a number of studies on adipose differentiation, adipocyte glucose uptake, lipolysis, apoptosis, regulation of expression of adipokines, and protein translocation. The cells are efficiently differentiated in the presence of PPARgammaagonists and in the absence of serum and albumin. SGBS adipocytes respond to insulin stimulation by increasing glucose uptake several-fold (EC50 approximately 100 pmol/l), and by very effectively inhibiting (IC50 approximately 10 pmol/l) catecholamine-stimulated lipolysis.
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Cites
Adipocyte differentiation from the inside out
Rosen, E. D., & MacDougald, O. A. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2066 · Cited by 2,607
Nampt/PBEF/Visfatin Regulates Insulin Secretion in β Cells as a Systemic NAD Biosynthetic Enzyme
Revollo, J. R., Körner, A., Mills, K. F., Satoh, A., Wang, T., Garten, A., Dasgupta, B., Sasaki, Y., Wolberger, C., Townsend, R. R., et al. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.09.003 · Cited by 911
Kintscher, U., Hartge, M., Hess, K., Foryst-Ludwig, A., Clemenz, M., Wabitsch, M., Fischer-Posovszky, P., Barth, T. F. E., Dragun, D., Skurk, T., et al. (2008) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.108.165100 · Cited by 692
Self-citationTXNIP regulates peripheral glucose metabolism in humans
Parikh, H., Carlsson, E., Chutkow, W. A., Johansson, L. E., Storgaard, H., Poulsen, P., Saxena, R., Ladd, C., Schulze, P. C., Mazzini, M. J., et al. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040158 · Cited by 495
Self-citation
Cited by
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Zebisch, K., Voigt, V., Wabitsch, M., & Brandsch, M. (2012) · Analytical Biochemistry · doi:10.1016/j.ab.2012.03.005 · Cited by 584
Self-citationCrewe, C., Funcke, J.-B., Li, S., Joffin, N., Gliniak, C. M., Ghaben, A. L., An, Y. A., Sadek, H. A., Gordillo, R., Akgul, Y., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.08.002 · Cited by 458
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Metadata
- Authors
- Fischer-Posovszky, P., Newell, F. S., Wabitsch, M., & Tornqvist, H. E.
- Venue
- Obesity Facts
- Publisher
- S. Karger AG
- Published
- 2008
- Volume
- 1
- Issue
- 4
- Pages
- 184-189
- ISSN
- 1662-4025 (ISSN-L)
- 1662-4033
- OpenAlex
- W2075496997
- Cited by
- 250
- References
- 4
- FWCI
- 3.22
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
