The DOI matches its Crossref record; 160 of the 160 references it cites were found in a registry or an index.
Cell Models and Their Application for Studying Adipogenic Differentiation in Relation to Obesity: A Review
Open accessAbstract
Over the last several years, the increasing prevalence of obesity has favored an intense study of adipose tissue biology and the precise mechanisms involved in adipocyte differentiation and adipogenesis. Adipocyte commitment and differentiation are complex processes, which can be investigated thanks to the development of diverse in vitro cell models and molecular biology techniques that allow for a better understanding of adipogenesis and adipocyte dysfunction associated with obesity. The aim of the present work was to update the different animal and human cell culture models available for studying the in vitro adipogenic differentiation process related to obesity and its co-morbidities. The main characteristics, new protocols, and applications of the cell models used to study the adipogenesis in the last five years have been extensively revised. Moreover, we depict co-cultures and three-dimensional cultures, given their utility to understand the connections between adipocytes and their surrounding cells in adipose tissue.
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Cited by
Yue, X., Nguyen, T. D., Zellmer, V., Zhang, S., & Zorlutuna, P. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.04.001 · Cited by 97
Obesogens: How They Are Identified and Molecular Mechanisms Underlying Their Action
Mohajer, N., Du, C. Y., Checkcinco, C., & Blumberg, B. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.780888 · Cited by 72
Obesity in Yap transgenic mice is associated with TAZ downregulation
Kamura, K., Shin, J., Kiyonari, H., Abe, T., Shioi, G., Fukuhara, A., & Sasaki, H. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.10.037 · Cited by 16
Metadata
- Authors
- Ruiz-Ojeda, F., Rupérez, A., Gomez-Llorente, C., Gil, A., & Aguilera, C.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2016-06-30
- Volume
- 17
- Issue
- 7
- Pages
- 1040
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2473078753
- Cited by
- 375
- References
- 160
- FWCI
- 24.87
- Type
- journal article
- Language
- en
- Open access
- gold
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- Ruiz-Ojeda, F., Rupérez, A., Gomez-Llorente, C., Gil, A., & Aguilera, C. (2016). Cell Models and Their Application for Studying Adipogenic Differentiation in Relation to Obesity: A Review. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms17071040
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
