Meeting the Nutritional Needs of the Low-Birth-Weight Infant
Abstract
Delivering adequate amounts of nutrients to premature infants at all times is challenging because the infant’s immature gastrointestinal tract is initially unable to accept feedings, necessitating the use of parenteral nutrition. In the past, inadequate amounts of nutrients have commonly been given to premature infants because the administration of nutrients was thought to be hazardous. Inadequate nutrient intakes have resulted in widespread postnatal growth restriction. Now that it is known that postnatal growth restriction is associated with poor neurocognitive development, efforts are made to increase nutrient intakes. In this review, nutrient requirements of premature infants that have been determined by the factorial and empirical methods are reviewed. Current good practices regarding parenteral nutrition are discussed, as are guidelines for the introduction and advancement of enteral feedings. Because of its trophic effects on the gastrointestinal tract and its anti-infectious effects, human milk is strongly preferred as the early feeding of choice for premature infants. Human milk also protects infants against necrotizing enterocolitis. Once full feeding is achieved, the challenge is to provide nutrients in amounts that support the infant’s growth like that of the fetus. In the case of the infant fed his/her mother’s milk or banked donor milk, nutrient fortification is necessary and is generally practiced. However, adequate intakes of protein are seldom achieved with routine fortification and methods of providing additional fortification are discussed.
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Breastmilk alone may be insufficient to meet the nutritional needs of MLBW infants.
“Further, breastmilk alone may be insufficient to meet the nutritional needs of MLBW infants [42, 44–46]; most facilities did not have alternatives readily available.”
From Facility-based care for moderately low birthweight infants in India, Malawi, and Tanzania (2023) · cites this paper as [45]
Cites
Breast milk and neonatal necrotising enterocolitis
Lucas, A., & Cole, T. J. (1990) · The Lancet · doi:10.1016/0140-6736(90)93304-8 · Cited by 1,601 · see citing works
Agostoni, C. V., Buonocore, G., Carnielli, V. P., Curtis, M. D., Darmaun, D., Decsi, T., Domellöf, M., Embleton, N. D., Fusch, C., Genzel‐Boroviczény, O., et al. (2009) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181adaee0 · Cited by 1,485 · see citing works
Self-citationEhrenkranz, R. A., Dusick, A. M., Vohr, B. R., Wright, L. L., Wrage, L. A., Poole, W. K., & for the National Institutes of Child Health and Human Development Neonatal Research Network (2006) · Pediatrics · doi:10.1542/peds.2005-1368 · Cited by 1,356 · see citing works
Sullivan, S. E., Schanler, R. J., Kim, J. H., Patel, A. L., Trawöger, R., Kiechl‐Kohlendorfer, U., Chan, G. M., Blanco, C. L., Abrams, S. A., Cotten, C. M., et al. (2009) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2009.10.040 · Cited by 965 · see citing works
Longitudinal Growth of Hospitalized Very Low Birth Weight Infants
Ehrenkranz, R. A., Younes, N., Lemons, J. A., Fanaroff, A. A., Donovan, E. F., Wright, L. L., Katsikiotis, V., Tyson, J. E., Oh, W., Shankaran, S., et al. (1999) · PEDIATRICS · doi:10.1542/peds.104.2.280 · Cited by 856 · see citing works
Embleton, N. D., Pang, N., & Cooke, R. J. (2001) · PEDIATRICS · doi:10.1542/peds.107.2.270 · Cited by 765 · see citing works
Body composition of the reference fetus.
Ziegler, E. E., O'Donnell, A. M., Nelson, S. E., & Fomon, S. J. (1976) · PubMed · Cited by 713 · see citing works
Self-citationSchanler, R. J., Shulman, R. J., & Lau, C. (1999) · PEDIATRICS · doi:10.1542/peds.103.6.1150 · Cited by 696 · see citing works
Extrauterine Growth Restriction Remains a Serious Problem in Prematurely Born Neonates
Clark, R. H., Thomas, P., & Peabody, J. L. (2003) · PEDIATRICS · doi:10.1542/peds.111.5.986 · Cited by 622 · see citing works
Stephens, B. E., Walden, R. V., Gargus, R. A., Tucker, R. J., McKinley, L. T., Mance, M. J., Nye, J., & Vohr, B. R. (2009) · PEDIATRICS · doi:10.1542/peds.2008-0211 · Cited by 563 · see citing works
Breast Milk as the Gold Standard for Protective Nutrients
Walker, A. W. (2010) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2009.11.021 · Cited by 517 · see citing works
Effect of Very Low Birth Weight and Subnormal Head Size on Cognitive Abilities at School Age
Hack, M., Breslau, N., Weissman, B. M., Aram, D., Klein, N., & Borawski, E. A. (1991) · New England Journal of Medicine · doi:10.1056/nejm199107253250403 · Cited by 502 · see citing works
Sisk, P. M., Lovelady, C., Dillard, R. G., Gruber, K. J., & O’Shea, T. M. (2007) · Journal of Perinatology · doi:10.1038/sj.jp.7211758 · Cited by 495 · see citing works
Franz, A. R., Pohlandt, F., Bode, H., Mihatsch, W. A., Sander, S., Kron, M., & Steinmacher, J. (2008) · PEDIATRICS · doi:10.1542/peds.2008-1352 · Cited by 447 · see citing works
Postnatal growth in VLBW infants: significant association with neurodevelopmental outcome
Latal, B., von Siebenthal, K., Kovari, H., Bucher, H. U., & Largo, R. H. (2003) · The Journal of Pediatrics · doi:10.1067/s0022-3476(03)00243-9 · Cited by 392 · see citing works
Nutrient Requirements For Preterm Infant Formulas
Klein, C. J. (2002) · Journal of Nutrition · doi:10.1093/jn/132.6.1395s · Cited by 381 · see citing works
Human Milk Feedings and Infection Among Very Low Birth Weight Infants
Hylander, M. A., Strobino, D. M., & Dhanireddy, R. (1998) · PEDIATRICS · doi:10.1542/peds.102.3.e38 · Cited by 369 · see citing works
The Effect of Maternal Milk on Neonatal Morbidity of Very Low-Birth-Weight Infants
Furman, L., Taylor, G. H., Minich, N. M., & Hack, M. (2003) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.157.1.66 · Cited by 301 · see citing works
Widdowson, E. M., & McCance, R. A. (1963) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1963.0051 · Cited by 298 · see citing works
Multicomponent fortified human milk for promoting growth in preterm infants
Kuschel, C. A., & Harding, J. E. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000343.pub2 · Cited by 290 · see citing works
Aggressive Early Total Parental Nutrition in Low-Birth-Weight Infants
Ibrahim, H. M., Jeroudi, M. A., Baier, R. J., Dhanireddy, R., & Krouskop, R. W. (2004) · Journal of Perinatology · doi:10.1038/sj.jp.7211114 · Cited by 264 · see citing works
Adjustable fortification of human milk fed to preterm infants: does it make a difference?
Arslanoğlu, S., Moro, G. E., & Ziegler, E. E. (2006) · Journal of Perinatology · doi:10.1038/sj.jp.7211571 · Cited by 260 · see citing works
Self-citationRivera, A., Bell, E. F., & Bier, D. M. (1993) · Pediatric Research · doi:10.1203/00006450-199302000-00003 · Cited by 227 · see citing works
Amino Acid Administration to Premature Infants Directly After Birth
Braake, F. W. J. T., van den Akker, C. H. P., Wattimena, D. J. L., Huijmans, J. G. M., & van Goudoever, J. B. (2005) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2005.05.038 · Cited by 215 · see citing works
Human intrauterine growth and nutrient accretion.
Sparks, J. W. (1984) · PubMed · Cited by 192 · see citing works
Dinerstein, A., Nieto, R., Solana, C., Pérez, G., Otheguy, L. E., & Larguía, A. M. (2006) · Journal of Perinatology · doi:10.1038/sj.jp.7211539 · Cited by 180 · see citing works
Intersite Differences in Weight Growth Velocity of Extremely Premature Infants
Olsen, I. E., Richardson, D. K., Schmid, C. H., Ausman, L. M., & Dwyer, J. T. (2002) · PEDIATRICS · doi:10.1542/peds.110.6.1125 · Cited by 167 · see citing works
Intestinal Permeability in Preterm Infants by Feeding Type: Mother's Milk Versus Formula
Taylor, S. N., Basile, L. A., Ebeling, M., & Wagner, C. L. (2009) · Breastfeeding Medicine · doi:10.1089/bfm.2008.0114 · Cited by 164 · see citing works
Human Milk and the Small Premature Infant
Fomon, S. J. (1977) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1977.02120170089018 · Cited by 159 · see citing works
Hirai, C., Ichiba, H., Saito, M., Shintaku, H., Yamano, T., & Kusuda, S. (2002) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200205000-00010 · Cited by 156 · see citing works
Optimization of human milk fortification for preterm infants: new concepts and recommendations
Arslanoğlu, S., Moro, G. E., Ziegler, E. E., & the WAPM Working Group on Nutrition (2010) · Journal of Perinatal Medicine · doi:10.1515/jpm.2010.073 · Cited by 153 · see citing works
Self-citationKuzma-O’Reilly, B., Dueñas, M., Greecher, C. P., Kimberlin, L. V., Mujsce, D. J., Miller, D., & Walker, D. (2003) · PEDIATRICS · doi:10.1542/peds.111.se1.e461 · Cited by 153 · see citing works
Kashyap, S., Schulze, K., Forsyth, M., Zucker, C., Dell, R. B., Ramakrishnan, R., & Heird, W. C. (1988) · The Journal of Pediatrics · doi:10.1016/s0022-3476(88)80388-3 · Cited by 151 · see citing works
Driessche, M. V. D., Peeters, K., Mariën, P., Ghoos, Y. F., Devlieger, H., & Veereman‐Wauters, G. (1999) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-199907000-00013 · Cited by 148 · see citing works
Kamitsuka, M. D., Horton, M. K., & Williams, M. A. (2000) · PEDIATRICS · doi:10.1542/peds.105.2.379 · Cited by 136 · see citing works
Kashyap, S., Forsyth, M., Zucker, C., Ramakrishnan, R., Dell, R. B., & Heird, W. C. (1986) · The Journal of Pediatrics · doi:10.1016/s0022-3476(86)80940-4 · Cited by 136 · see citing works
Nutrient intakes and growth of very low birth weight infants.
Carlson, S., & Ziegler, E. (1998) · PubMed · Cited by 135 · see citing works
Self-citationIntelligence of very preterm or very low birthweight infants in young adulthood
Weisglas‐Kuperus, N., Hille, E. T. M., Duivenvoorden, H. J., Finken, M. J. J., Wit, J. M., van Buuren, S., van Goudoever, J. B., Verloove-Vanhorick, S. P., & for the Dutch POPS-19 Collaborative Study Group* (2008) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/adc.2007.135095 · Cited by 130 · see citing works
Role of human milk components in gastrointestinal development: Current knowledge and future NEEDS
Donovan, S. M. (2006) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2006.06.052 · Cited by 111 · see citing works
POLBERGER, S. K. T., Räihä, N. C. R., Juvonen, P. O., Moro, G. E., MINOLI, I., & Warm, A. (1999) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1002/j.1536-4801.1999.tb02424.x · Cited by 111 · see citing works
Septicemia in the First Week of Life in a Norwegian National Cohort of Extremely Premature Infants
Rønnestad, A. E., Abrahamsen, T. G., Medbö, S., Reigstad, H. M., Lossius, K., Kaaresen, P. I., Engelund, I. E., Irgens, L. M., & Markestad, T. (2005) · PEDIATRICS · doi:10.1542/peds.2004-1834 · Cited by 105 · see citing works
Georgieff, M., Hoffman, J. S., Pereira, G. R., BERNBAUM, J. C., & Hoffman-Williamson, M. (1985) · The Journal of Pediatrics · doi:10.1016/s0022-3476(85)80028-7 · Cited by 99 · see citing works
Human Milk Consumption and Full Enteral Feeding Among Infants Who Weigh ≤1250 Grams
Sisk, P. M., Lovelady, C. A., Gruber, K. J., Dillard, R. G., & O’Shea, T. M. (2008) · PEDIATRICS · doi:10.1542/peds.2007-2110 · Cited by 79 · see citing works
Enteral feeding for very low birth weight infants: reducing the risk of necrotising enterocolitis
Chauhan, M., Henderson, G., & McGuire, W. L. (2007) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/adc.2007.115824 · Cited by 78 · see citing works
Ballabh, P., Kumari, J., Krauss, A. N., Shin, J. J., Jain, A., Auld, P. A. M., LESSER, M. L., & Cunningham–Rundles, S. (2003) · PEDIATRICS · doi:10.1542/peds.111.3.461 · Cited by 73 · see citing works
Fetal growth and postnatal growth failure in very‐low‐birthweight infants
Marks, K. A., Reichman, B. L., Lusky, A., & Zmora, E. (2006) · Acta Paediatrica · doi:10.1111/j.1651-2227.2006.tb02213.x · Cited by 72 · see citing works
Postnatal Malnutrition of Extremely Low Birth-Weight Infants With Catch-Up Growth Postdischarge
Ernst, K., Radmacher, P. G., Rafail, S. T., & Adamkin, D. H. (2003) · Journal of Perinatology · doi:10.1038/sj.jp.7210974 · Cited by 67 · see citing works
Snyderman, S. E., Boyer, A., Kogut, M. D., & Holt, L. E. (1969) · The Journal of Pediatrics · doi:10.1016/s0022-3476(69)80221-0 · Cited by 67 · see citing works
Does the Enteral Feeding Advancement Affect Short‐term Outcomes in Very Low Birth Weight Infants?
Härtel, C., Haase, B., Carmo, K. B., Gebauer, C. M., Kattner, E., Kribs, A., Segerer, H., Teig, N., der Wense, A. V., Wieg, C., et al. (2009) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e31818c5fc3 · Cited by 62 · see citing works
Kashyap, S., & Heird, W. C. (1994) · Europe PMC (PubMed Central) · Cited by 60 · see citing works
Olhager, E., & Forsum, E. (2003) · Acta Paediatrica · doi:10.1080/08035250310005396 · Cited by 48 · see citing works
Early nutrition of very low birth weight infants
Ziegler, E. E., & Carlson, S. J. (2009) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767050802630169 · Cited by 47 · see citing works
Self-citationRees, D. C., Dick, M. C., Height, S. E., O’Driscoll, S., Pohl, K., Goss, D. E., & Deane, C. R. (2008) · PEDIATRICS · doi:10.1542/peds.2007-2771 · Cited by 40 · see citing works
Audit of feeding practices in babies <1200 g or 30 weeks gestation during the first month of life
Cormack, B. E., & Bloomfield, F. H. (2006) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2006.00897.x · Cited by 36 · see citing works
Simmer, K. N., Metcalf, R. G., & Daniels, L. (1997) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.1997.tb00992.x · Cited by 34 · see citing works
Determinants of energy expenditure in ventilated preterm infants
DeMarie, M. P., Hoffenberg, A. S., Biggerstaff, S. L., Jeffers, B. W., Hay, W. W., & Thureen, P. J. (1999) · Journal of Perinatal Medicine · doi:10.1515/jpm.1999.062 · Cited by 25 · see citing works
Protein requirements of preterm infants
Ziegler, E. E. (1986) · Cited by 23 · see citing works
Self-citationMalnutrition in the Premature Infant
Ziegler, E. E. (1991) · Acta Paediatrica · doi:10.1111/j.1651-2227.1991.tb12008.x · Cited by 17 · see citing works
Self-citationGrowth in high risk infants <1500 g birthweight during the first 5 weeks
Loui, A., Tsalikaki, E., Maier, K., Walch, E., Kamarianakis, Y., & Obladen, M. (2008) · Early Human Development · doi:10.1016/j.earlhumdev.2008.04.005 · Cited by 16 · see citing works
Nutritional adequacy of human breast milk for prematurely born infants.
Forbes, G. B., & Lebenthal, E. (1989) · Cited by 5 · see citing works
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Donor Human Milk for Preterm Infants
Arslanoğlu, S., Corpeleijn, W. E., Moro, G. E., Braegger, C., Campoy, C., Colomb, V., Décsi, T., Domellöf, M., Fewtrell, M. S., Hojsak, I., et al. (2013) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3182a3af0a · Cited by 411 · see citing works
Weight Growth Velocity and Postnatal Growth Failure in Infants 501 to 1500 Grams: 2000–2013
Horbar, J. D., Ehrenkranz, R. A., Badger, G. J., Edwards, E. M., Morrow, K. A., Soll, R. F., Buzas, J. S., Bertino, E., Gagliardi, L., & Bellù, R. (2015) · PEDIATRICS · doi:10.1542/peds.2015-0129 · Cited by 318 · see citing works
Arslanoğlu, S., Boquien, C., King, C. A., Lamireau, D., Tonetto, P., Barnett, D., Bertino, E., Gayà, A., Gebauer, C. M., Grøvslien, A., et al. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00076 · Cited by 318 · see citing works
Fenton, T. R., Nasser, R., Eliasziw, M., Kim, J. H., Bilan, D., & SAUVE, R. S. (2013) · BMC Pediatrics · doi:10.1186/1471-2431-13-92 · Cited by 310 · see citing works
Invited Review: The preterm pig as a model in pediatric gastroenterology
Sangild, P. T., Thymann, T., Schmidt, M. H., Stoll, B., Burrin, D. G., & Buddington, R. K. (2013) · Journal of Animal Science · doi:10.2527/jas.2013-6359 · Cited by 262 · see citing works
Moltu, S. J., Strømmen, K., Blakstad, E. W., Almaas, A. N., Westerberg, A. C., Brække, K., Rønnestad, A. E., Nakstad, B., Berg, J. P., Veierød, M. B., et al. (2012) · Clinical Nutrition · doi:10.1016/j.clnu.2012.09.004 · Cited by 168 · see citing works
Advances in nutrition of the newborn infant
Harding, J. E., Cormack, B. E., Alexander, T., Alsweiler, J. M., & Bloomfield, F. H. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30552-4 · Cited by 166 · see citing works
Leoz, M. L. A. D., Gaerlan, S. C., Strum, J. S., Dimapasoc, L. M., Mirmiran, M., Tancredi, D. J., Smilowitz, J. T., Kalanetra, K. M., Mills, D. A., German, J. B., et al. (2012) · Journal of Proteome Research · doi:10.1021/pr3004979 · Cited by 141 · see citing works
The individual-specific and diverse nature of the preterm infant microbiota
Barrett, E., Kerr, C., Murphy, K., O'Sullivan, O., Ryan, C. A., Dempsey, E. M., Murphy, B. P., O'Toole, P. W., Cotter, P. D., Fitzgerald, G. F., et al. (2013) · Archives of Disease in Childhood - Fetal and Neonatal Edition · doi:10.1136/archdischild-2012-303035 · Cited by 120 · see citing works
BMI Curves for Preterm Infants
Olsen, I. E., Lawson, M. L., Ferguson, N., Cantrell, R., Grabich, S. C., Zemel, B. S., & Clark, R. H. (2015) · PEDIATRICS · doi:10.1542/peds.2014-2777 · Cited by 118 · see citing works
Preterm human milk composition: a systematic literature review
Boyce, C., Watson, M., Lazidis, G., Reeve, S., Dods, K., Simmer, K. N., & McLeod, G. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516003007 · Cited by 103 · see citing works
Total parenteral nutrition for the very low birth weight infant
Patel, P., & Bhatia, J. J. S. (2016) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2016.08.002 · Cited by 90 · see citing works
Fortification of human milk for preterm infants
Radmacher, P. G., & Adamkin, D. H. (2016) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2016.08.004 · Cited by 81 · see citing works
Enhanced Feeding and Diminished Postnatal Growth Failure in Very‐Low‐Birth‐Weight Infants
Moltu, S. J., Blakstad, E. W., Strømmen, K., Almaas, A. N., Nakstad, B., Rønnestad, A. E., Brække, K., Veierød, M. B., Drevon, C. A., Iversen, P. O., et al. (2013) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000000220 · Cited by 70 · see citing works
John, A., Sun, R., Maillart, L. M., Schaefer, A. J., Spence, E. H., & Perrin, M. T. (2019) · PLoS ONE · doi:10.1371/journal.pone.0210610 · Cited by 69 · see citing works
Human Milk and the Premature Infant
Bhatia, J. J. S. (2013) · Annals of Nutrition and Metabolism · doi:10.1159/000351537 · Cited by 69 · see citing works
Sangild, P. T., Ney, D. M., Sigalet, D. L., Vegge, A., & Burrin, D. G. (2014) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00088.2014 · Cited by 68 · see citing works
Brownell, E., Matson, A. P., Smith, K. C., Moore, J. E., Esposito, P. A., Lussier, M. M., Lerer, T., & Hagadorn, J. I. (2018) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000001959 · Cited by 66 · see citing works
The microbiome and disorders of the central nervous system
Felice, V. D., & O'Mahony, S. M. (2017) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2017.06.016 · Cited by 60 · see citing works
Human Milk and Human Milk Fortifiers
Ziegler, E. E. (2014) · World review of nutrition and dietetics · doi:10.1159/000358470 · Cited by 60 · see citing works
Self-citationPreterm nutrition and neurodevelopmental outcomes
Skinner, A. M., & Narchı, H. (2021) · World Journal of Methodology · doi:10.5662/wjm.v11.i6.278 · Cited by 52 · see citing works
Fortification of Breast Milk With Preterm Formula Powder vs Human Milk Fortifier in Preterm Neonates
Chinnappan, A., Sharma, A., Agarwal, R. K., Thukral, A., Deorari, A. K., & Sankar, M. J. (2021) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2021.0678 · Cited by 51 · see citing works
Raiten, D. J., Steiber, A. L., Carlson, S. E., Griffin, I. J., Anderson, D. M., Hay, W. W., Robins, S., Neu, J., Georgieff, M., Groh‐Wargo, S. L., et al. (2016) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.117309 · Cited by 51 · see citing works
Target Fortification of Breast Milk: How Often Should Milk Analysis Be Done?
Rochow, N., Fusch, G., Zapanta, B., Ali, A., Barui, S., & Fusch, C. (2015) · Nutrients · doi:10.3390/nu7042297 · Cited by 50 · see citing works
Higher Protein Intake Improves Length, Not Weight, z Scores in Preterm Infants
Olsen, I. E., Harris, C. L., Lawson, M. L., & Berseth, C. L. (2013) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000000237 · Cited by 49 · see citing works
Preterm formula use in the preterm very low birth weight infant
Hay, W. W., & Hendrickson, K. (2016) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2016.08.005 · Cited by 46 · see citing works
Burianová, I., Bronský, J., Pavlı́ková, M., Janota, J., & Malý, J. (2019) · Early Human Development · doi:10.1016/j.earlhumdev.2019.104832 · Cited by 45 · see citing works
Early energy restriction in premature infants and bronchopulmonary dysplasia: a cohort study
Uberos, J., Jiménez-Montilla, S., Molina-Oya, M., & Garcia-Serrano, J. L. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520000240 · Cited by 44 · see citing works
Dritsakou, K., Liosis, G., Valsami, G. N., Polychronopoulos, E., & Skouroliakou, M. (2015) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2015.1038232 · Cited by 42 · see citing works
Ananthan, A., Balasubramanian, H., Rao, S. C., & Patole, S. (2020) · Advances in Nutrition · doi:10.1093/advances/nmaa039 · Cited by 42 · see citing works
Nutrition for the Extremely Preterm Infant
McNelis, K., Fu, T. T., & Poindexter, B. B. (2017) · Clinics in Perinatology · doi:10.1016/j.clp.2017.01.012 · Cited by 41 · see citing works
What Is the Impact of NICU-Dedicated Lactation Consultants? An Evidence-Based Practice Brief
Mercado, K., Vittner, D. J., & McGrath, J. M. (2019) · Advances in Neonatal Care · doi:10.1097/anc.0000000000000602 · Cited by 39 · see citing works
Human Milk Analysis Using Mid‐Infrared Spectroscopy
Groh‐Wargo, S. L., Valentic, J., Khaira, S., Super, D. M., & Collin, M. F. (2015) · Nutrition in Clinical Practice · doi:10.1177/0884533615596508 · Cited by 37 · see citing works
Butler, T. J., Szekely, L. J., & Grow, J. L. (2013) · Journal of Perinatology · doi:10.1038/jp.2013.66 · Cited by 37 · see citing works
Coscia, A., Bertino, E., Tonetto, P., Peila, C., Cresi, F., Arslanoğlu, S., Moro, G. E., Spada, E., Milani, S., Giribaldi, M., et al. (2018) · Nutrition Journal · doi:10.1186/s12937-017-0308-8 · Cited by 36 · see citing works
Ng, D. V. Y., Brennan, J., Unger, S. L., Bando, N., Gibbins, S., Nash, A. H., Kiss, A., & O’Connor, D. L. (2015) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607115594674 · Cited by 35 · see citing works
Optimising preterm nutrition: present and future
Brennan, A., Murphy, B. P., & Kiely, M. E. (2016) · Proceedings of The Nutrition Society · doi:10.1017/s0029665116000136 · Cited by 35 · see citing works
A Novel Donkey Milk–derived Human Milk Fortifier in Feeding Preterm Infants
Bertino, E., Cavallarin, L., Cresi, F., Tonetto, P., Peila, C., Ansaldi, G., Raia, M., Varalda, A., Giribaldi, M., Conti, A., et al. (2018) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000002168 · Cited by 35 · see citing works
Ahnfeldt, A. M., Hyldig, N., Li, Y., Kappel, S. S., Aunsholdt, L., Sangild, P. T., & Zachariassen, G. (2019) · Trials · doi:10.1186/s13063-019-3367-7 · Cited by 34 · see citing works
Protein supplementation of human milk for promoting growth in preterm infants
Amissah, E. A., Brown, J., & Harding, J. E. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000433.pub2 · Cited by 34 · see citing works
Gidi, N. W., Goldenberg, R. L., Nigussie, A. K., McClure, E. M., Mekasha, A., Worku, B., Siebeck, M., Genzel‐Boroviczény, O., & Muhe, L. M. (2020) · BMJ Paediatrics Open · doi:10.1136/bmjpo-2020-000765 · Cited by 34 · see citing works
Grace, E., Hilditch, C., Gomersall, J. S., Collins, C. T., Rumbold, A. R., & Keir, A. (2020) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/archdischild-2020-319406 · Cited by 33 · see citing works
Parenteral Nutrition in Premature Infants
Senterre, T., Terrin, G., Curtis, M. D., & Rigo, J. (2015) · Springer eBooks · doi:10.1007/978-3-319-17169-2_7 · Cited by 33 · see citing works
Improving growth in preterm infants during initial hospital stay: principles into practice
Cooke, R. J. (2016) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/archdischild-2015-310097 · Cited by 33 · see citing works
Østergaard, M. V., Shen, R. L., Støy, A. C. F., Skovgaard, K., Krych, Ł., Leth, S. S., Nielsen, D. S., Hartmann, B., Bering, S. B., Schmidt, M. H., et al. (2015) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114566463 · Cited by 32 · see citing works
Do recommended protein intakes improve neurodevelopment in extremely preterm babies?
Cester, E. A., Bloomfield, F. H., Taylor, J., Smith, S., & Cormack, B. E. (2015) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/archdischild-2014-307521 · Cited by 32 · see citing works
History of Milk Banking: From Origin to Present Time
Moro, G. E. (2018) · Breastfeeding Medicine · doi:10.1089/bfm.2018.29077.gem · Cited by 32 · see citing works
Preterm newborn's postnatal growth patterns: how to evaluate them
Silveira, R. C., & Procianoy, R. S. (2018) · Jornal de Pediatria · doi:10.1016/j.jped.2018.10.006 · Cited by 32 · see citing works
Østergaard, M. V., Bering, S. B., Jensen, M. L., Thymann, T., Purup, S., Diness, M., Schmidt, M. H., & Sangild, P. T. (2013) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607113489313 · Cited by 30 · see citing works
Protein supplementation of human milk for promoting growth in preterm infants
Amissah, E. A., Brown, J., & Harding, J. E. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000433.pub3 · Cited by 30 · see citing works
The association of macronutrients in human milk with the growth of preterm infants
Lin, Y.-H., Hsu, Y.-C., Lin, M., Chen, C., & Wang, T. (2020) · PLoS ONE · doi:10.1371/journal.pone.0230800 · Cited by 29 · see citing works
Parat, S., Raza, P. C., Kamleh, M. K., Super, D. M., & Groh‐Wargo, S. L. (2020) · Nutrients · doi:10.3390/nu12041156 · Cited by 28 · see citing works
High Early Parenteral Lipid in Very Preterm Infants: A Randomized-Controlled Trial
Alburaki, W., Yusuf, K., Dobry, J., Sheinfeld, R., & Alshaikh, B. N. (2020) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2020.08.024 · Cited by 28 · see citing works
Sauer, C. W., Boutin, M. A., & Kim, J. H. (2016) · Journal of Human Lactation · doi:10.1177/0890334416672200 · Cited by 28 · see citing works
Feeding Patterns during the First 2 Years and Health Outcome
Haschke, F., Haiden, N., Detzel, P., Yarnoff, B., Allaire, B. T., & Haschke‐Becher, E. (2013) · Annals of Nutrition and Metabolism · doi:10.1159/000351575 · Cited by 27 · see citing works
Nutrition Practices and Predictors of Postnatal Growth in Preterm Infants During Hospitalization
McKenzie, B. L., Edmonds, L. K., Thomson, R., Haszard, J. J., & Houghton, L. A. (2017) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000001747 · Cited by 27 · see citing works
Neonatal management and safe discharge of late and moderate preterm infants
Whyte, R. K. (2012) · Seminars in Fetal and Neonatal Medicine · doi:10.1016/j.siny.2012.02.004 · Cited by 26 · see citing works
Kociszewska‐Najman, B., Borek-Dzięcioł, B., Szpotanska‐Sikorska, M., Wilkos, E., Pietrzak, B., & Wielgoś, M. (2012) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2011.648239 · Cited by 26 · see citing works
Cresi, F., Maggiora, E., Pirra, A., Tonetto, P., Rubino, C., Cavallarin, L., Giribaldi, M., Moro, G. E., Bertino, E., Peila, C., et al. (2020) · Nutrients · doi:10.3390/nu12072142 · Cited by 26 · see citing works
Nutritional support for low birth weight infants: insights from animal studies
Li, N., Wang, W., Wu, G., & Wang, J. (2017) · British Journal Of Nutrition · doi:10.1017/s000711451700126x · Cited by 25 · see citing works
Raith, W., Resch, B., Pichler, G., Zotter, H., Urlesberger, B., & Mueller, W. D. (2013) · Europe PMC (PubMed Central) · Cited by 25 · see citing works
Bloomfield, F. H., Crowther, C. A., Harding, J. E., Conlon, C. A., Jiang, Y., & Cormack, B. E. (2015) · BMC Pediatrics · doi:10.1186/s12887-015-0411-y · Cited by 25 · see citing works
Epigenetics and neonatal nutrition
Siméoni, U., Yzydorczyk, C., Siddeek, B., & Benahmed, M. (2014) · Early Human Development · doi:10.1016/s0378-3782(14)50007-2 · Cited by 25 · see citing works
Nutrition Management for the Promotion of Growth in Very Low Birth Weight Premature Infants
Prince, A., & Groh‐Wargo, S. L. (2013) · Nutrition in Clinical Practice · doi:10.1177/0884533613506752 · Cited by 23 · see citing works
Use of human milk and fortification in the NICU
Adamkin, D. H. (2022) · Journal of Perinatology · doi:10.1038/s41372-022-01532-0 · Cited by 23 · see citing works
Onay, Ö. S., Korkmaz, A., Yiğit, Ş., & Yurdakök, M. (2013) · European Journal of Pediatrics · doi:10.1007/s00431-012-1922-2 · Cited by 23 · see citing works
Peripherally inserted central catheters optimize nutrient intake in moderately preterm infants
Smazal, A. L., Kavars, A. B., Carlson, S. J., Colaizy, T. T., & Dagle, J. M. (2016) · Pediatric Research · doi:10.1038/pr.2016.73 · Cited by 21 · see citing works
Dritsakou, K., Liosis, G., Valsami, G. N., Polychronopoulos, E., Souliotis, K. N., & Skouroliakou, M. (2016) · Midwifery · doi:10.1016/j.midw.2016.06.015 · Cited by 21 · see citing works
Turkish Neonatal Society guideline on the parenteral nutrition in preterm infants
Türkyılmaz, C., Bilgen, H. S., & Kültürsay, N. (2019) · Türk Pediatri Arşivi · doi:10.5152/turkpediatriars.2018.01812 · Cited by 21 · see citing works
Gao, C., Miller, J. M., Collins, C. T., & Rumbold, A. R. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007090.pub2 · Cited by 20 · see citing works
Oropharyngeal colostrum immunotherapy and nutrition in preterm newborns: meta-analysis
Ramos, M. D. S. X., Martins, C. D. C., Souza, E. S., Vieira, G. O., Gomes‐Filho, I. S., Figueiredo, A. C. M. G., Pereira, M. G., & da Cruz, S. S. (2021) · Revista de Saúde Pública · doi:10.11606/s1518-8787.2021055003051 · Cited by 20 · see citing works
McLeod, G., Farrent, S., Gilroy, M., Page, D., Oliver, C. J., Richmond, F., & Cormack, B. E. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2021.642474 · Cited by 19 · see citing works
Kappel, S. S., Sangild, P. T., Ahnfeldt, A. M., Jóhannsdóttir, V., Soernsen, L. J., Bak, L. B., Friborg, C. R., Möller, S., Zachariassen, G., & Aunsholt, L. (2022) · Nutrients · doi:10.3390/nu14224756 · Cited by 19 · see citing works
Uygur, Ö., Yalaz, M., Can, N., Köroğlu, Ö. A., & Kültürsay, N. (2019) · Breastfeeding Medicine · doi:10.1089/bfm.2018.0142 · Cited by 18 · see citing works
Basu, S., Upadhyay, J., Singh, P. K., & Kumar, M. (2020) · European Journal of Pediatrics · doi:10.1007/s00431-020-03677-6 · Cited by 18 · see citing works
Highly Concentrated Preterm Formula as an Alternative to Powdered Human Milk Fortifier
Willeitner, A., Anderson, M., & Lewis, J. (2017) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000001638 · Cited by 18 · see citing works
Extrauterine growth restriction: Universal problem among premature infants
de Freitas, B. A. C., Priore, S. E., Lima, L. M., & Franceschini, S. D. C. C. (2016) · Revista de Nutrição · doi:10.1590/1678-98652016000100006 · Cited by 17 · see citing works
Khan, Z., Marinschek, S., Pahsini, K., Scheer, P., Morris, N., Urlesberger, B., & Dunitz‐Scheer, M. (2015) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000000931 · Cited by 17 · see citing works
Sandhu, A., Fast, S., Bonnar, K., Baier, R. J., & Narvey, M. R. (2017) · Breastfeeding Medicine · doi:10.1089/bfm.2017.0017 · Cited by 17 · see citing works
Brown, L. D., Hendrickson, K., Masor, M. L., & Hay, W. W. (2014) · Clinics in Perinatology · doi:10.1016/j.clp.2014.02.002 · Cited by 17 · see citing works
Cardoso, M., Virella, D., Papoila, A. L., Alves, M., Macedo, I., Silva, D. E., & Pereira‐da‐Silva, L. (2023) · Nutrients · doi:10.3390/nu15061533 · Cited by 16 · see citing works
Nutritional Care of Preterm Infants
Koletzko, B. V., Poindexter, B. B., & Uauy, R. D. (2016) · Cited by 16 · see citing works
IV. Individualized Fortification of Human Milk
Arslanoğlu, S. (2015) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/01.mpg.0000471452.85920.4d · Cited by 16 · see citing works
Álvarez, M. J. Á., Rodríguez‐González, M. D., Rosón, M., Lapeña, S., Gómez-Salgado, J. C., & García, D. F. (2019) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2019.03.015 · Cited by 16 · see citing works
Lin, Y., Chen, Y., Huang, C., & Shieh, C.-C. K. (2020) · Nutrients · doi:10.3390/nu12082229 · Cited by 16 · see citing works
Patient and practice factors affecting growth of infants with systemic-to-pulmonary shunt
McCrary, A. W., Clabby, M. L., & Mahle, W. T. (2012) · Cardiology in the Young · doi:10.1017/s1047951112001382 · Cited by 16 · see citing works
Parenteral Nutrition in Very Low Birth Weight Preterm Infants.
Riskin, A., Hartman, C., & Shamir, R. (2015) · PubMed · Cited by 16 · see citing works
The “Fortilat” Randomized Clinical Trial Follow-Up: Neurodevelopmental Outcome at 18 Months of Age
Peila, C., Spada, E., Deantoni, S., Iuliano, E., Moro, G. E., Giribaldi, M., Cavallarin, L., Cresi, F., & Coscia, A. (2020) · Nutrients · doi:10.3390/nu12123807 · Cited by 15 · see citing works
Buffet‐Bataillon, S., Bellanger, A., Boudry, G., Gangneux, J., Yverneau, M., Beuchée, A., Blat, S., & Huërou‐Luron, I. L. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.676622 · Cited by 15 · see citing works
Vain, N. E., Fariña, D., & Vázquez, L. (2012) · Early Human Development · doi:10.1016/s0378-3782(12)70016-6 · Cited by 15 · see citing works
Evidence-Based Guidelines for Optimization of Nutrition for the Very Low Birthweight Infant
Torrazza, R. J. M., & Neu, J. (2013) · NeoReviews · doi:10.1542/neo.14-7-e340 · Cited by 15 · see citing works
Human Milk Feedings in the Neonatal Intensive Care Unit
Meier, P. P., Patel, A. L., Bigger, H. R., Chen, Y., Johnson, T. J., Rossman, B., & Engstrom, J. L. (2015) · Springer eBooks · doi:10.1007/978-1-4614-7836-2_126 · Cited by 15 · see citing works
Macedo, I., Pereira-da-Silva, L., Brito, L., & Cardoso, M. (2019) · Einstein (São Paulo) · doi:10.31744/einstein_journal/2019ao4607 · Cited by 13 · see citing works
Kumar, M., Upadhyay, J., & Basu, S. (2021) · Indian Pediatrics · doi:10.1007/s13312-021-2166-x · Cited by 13 · see citing works
Nutritional Support for Premature Infants in the Neonatal Intensive Care Unit
Ditzenberger, G. R. (2014) · Critical Care Nursing Clinics of North America · doi:10.1016/j.ccell.2014.02.003 · Cited by 13 · see citing works
Considerations in Meeting Protein Needs of the Human Milk–Fed Preterm Infant
Wagner, J., Hanson, C., & Anderson‐Berry, A. (2014) · Advances in Neonatal Care · doi:10.1097/anc.0000000000000108 · Cited by 13 · see citing works
Newkirk, M., Shakeel, F., Parimi, P. S., Rothpletz‐Puglia, P., Patusco, R., Marcus, A. F., & Brody, R. A. (2018) · Nutrition in Clinical Practice · doi:10.1002/ncp.10060 · Cited by 13 · see citing works
NUTRITIONAL PRACTICES IN VERY LOW BIRTH WEIGHT INFANTS: A NATIONAL SURVEY
Couce, M. L., de Pipaón, M. S., Closa, R., Gormáz, M., Linés, M., Narbona, E., Rodrı́guez, G., Uberos, J., & Zozaya, C. (2017) · Nutrición Hospitalaria · doi:10.20960/nh.1068 · Cited by 12 · see citing works
Lund, A., Löfqvist, C., Pivodic, A., Lundgren, P., Hård, A., Hellström, A., & Pupp, I. H. (2019) · Acta Paediatrica · doi:10.1111/apa.15102 · Cited by 12 · see citing works
Hill, N. S., Cormack, B. E., Little, B., & Bloomfield, F. H. (2020) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1750 · Cited by 12 · see citing works
- Authors
- Ziegler, E. E.
- Affiliations
- University of Iowa (US)
- Corresponding author
- Ziegler, Ekhard E.
- Venue
- Annals of Nutrition and Metabolism
- Publisher
- S. Karger AG
- Published
- 2011
- Volume
- 58
- Issue
- Suppl. 1
- Pages
- 8-18
- ISSN
- 0250-6807 (ISSN-L)
- 1421-9697
- OpenAlex
- W2075593674
- Cited by
- 217
- References
- 60
- Citations by year
- 2026: 6 · 2025: 7 · 2024: 5 · 2023: 9 · 2022: 9 · 2021: 15 · 2020: 25 · 2019: 13 · 2018: 21 · 2017: 16 · 2016: 24 · 2015: 25 · 2014: 16 · 2013: 16 · 2012: 7
- FWCI
- 1.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Nutrition and Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Development and Preterm Care
- Keywords
- low birth weight infants, preterm infants, nutrient requirements, parenteral nutrition, enteral nutrition, postnatal growth restriction, neurocognitive development, breast milk, donor human milk, necrotizing enterocolitis, nutrient fortification, protein intake, factorial method, empirical methods
- MeSH terms
- Energy Intake, Dietary Proteins, Enteral Nutrition, Food, Fortified, Humans, Infant, Infant Nutritional Physiological Phenomena, Infant, Low Birth Weight, Infant, Newborn, Infant, Premature, Milk, Human, Nutritional Requirements, Parenteral Nutrition, Guidelines as Topic, Sepsis, Enterocolitis, Necrotizing, Empirical Research, Infant Formula, Gastrointestinal Tract
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