The Skin of Domestic Mammals as a Model for the Human Skin, with Special Reference to the Domestic Pig1
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The swine has been described as the most adequate model for human wound healing.
“Although the inflammatory response may be different from humans, the swine has been described as the most adequate model for human wound healing.26–29”
From Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine (2017) · cites this paper as [26]
The subcutaneous adipose tissue of the swine has a similarly high elastic and collagen fiber content and the animals show a healing mechanism comparable to humans.
“The subcutaneous adipose tissue of the swine has a similarly high elastic and collagen fiber content and the animals show a healing mechanism comparable to humans.26,27,29”
From Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine (2017) · cites this paper as [26]
Like humans, swine has a thick epidermis (70-150 μm), sparse body hair, and a similar composition of the skin lipid layer.
“Like humans it has a thick epidermis (70–150 μm), sparse body hair, and a similar composition of the skin lipid layer.26,29”
From Detailed Analysis of Insulin Absorption Variability and the Tissue Response to Continuous Subcutaneous Insulin Infusion Catheter Implantation in Swine (2017) · cites this paper as [26]
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The pig as a model for human wound healing
Sullivan, T. P., Eaglstein, W. H., Davis, S. C., & Mertz, P. (2001) · Wound Repair and Regeneration · doi:10.1046/j.1524-475x.2001.00066.x · Cited by 1,091 · see citing works
Confocal laser scanning microscopy of porcine skin: implications for human wound healing studies
VARDAXIS, N. J., BRANS, T. A., BOON, M. E., KREIS, R. W., & MARRES, L. M. (1997) · Journal of Anatomy · doi:10.1046/j.1469-7580.1997.19040601.x · Cited by 177 · see citing works
Skin whitening cosmetics: feedback and challenges in the development of natural skin lighteners
Burger, P., Landreau, A., Azoulay, S., Michel, T., & Fernandez, X. (2016) · Cosmetics · doi:10.3390/cosmetics3040036 · Cited by 152 · see citing works
Helton, K. L., Ratner, B. D., & Wisniewski, N. A. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500317 · Cited by 125 · see citing works
Keratin dressings speed epithelialization of deep partial-thickness wounds
Pechter, P. M., Gil, J., Valdes, J., Tomic‐Canic, M., Pastar, I., Stojadinovic, O., Kirsner, R. S., & Davis, S. C. (2012) · Wound Repair and Regeneration · doi:10.1111/j.1524-475x.2012.00768.x · Cited by 85 · see citing works
Bishop, J. H., Fox, J. R., Maple, R., Loretan, C., Badger, G. J., Henry, S. M., Vizzard, M. A., & Langevin, H. M. (2016) · PLOS ONE · doi:10.1371/journal.pone.0147393 · Cited by 64 · see citing works
Hauzenberger, J. R., Hipszer, B. R., Loeum, C., McCue, P. A., DeStefano, M., Torjman, M. C., Kaner, M. T., Dinesen, A. R., Chervoneva, I., Pieber, T. R., et al. (2017) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2017.0175 · Cited by 39 · see citing works
“The subcutaneous adipose tissue of the swine has a similarly high elastic and collagen fiber content and the animals show a healing mechanism comparable to humans.(26,27,29) When insulin is infused, an insulin pump produces a hydrostatic pressure differential between the inside of the CSII cannula and the adjacent sub…”
Background
- Authors
- Meyer, W., Schwarz, R., & Neurand, K.
- Affiliations
- University of Veterinary Medicine Hannover, Foundation (DE)
- Venue
- Current Problems in Dermatology
- Publisher
- S. Karger AG
- Published
- 2015-04-16
- Volume
- 7
- Pages
- 39-52
- ISSN
- 1421-5721 (ISSN-L)
- 1662-2944
- OpenAlex
- W22120313
- Cited by
- 454
- References
- 0
- Citations by year
- 2026: 9 · 2025: 13 · 2024: 16 · 2023: 9 · 2022: 14 · 2021: 14 · 2020: 13 · 2019: 23 · 2018: 12 · 2017: 16 · 2016: 21 · 2015: 18 · 2014: 18 · 2013: 15 · 2012: 20
- FWCI
- 126.30
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Current problems in dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Skin and Cellular Biology Research
- Health Sciences › Medicine › Urology › Comparative Animal Anatomy Studies
- Keywords
- skin, domestic mammals, human skin model, domestic pigs, porcine skin, comparative dermatology
- MeSH terms
- Animals, Cats, Dogs, Epidermis, Hair, Histocytochemistry, Humans, Models, Biological, Sebaceous Glands, Skin, Skin Physiological Phenomena, Species Specificity, Sweat Glands, Swine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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