The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Nuclear Factor κB Signaling in Atherogenesis
Open accessAbstract
Atherosclerosis is an inflammatory disease, characterized by the accumulation of macrophage-derived foam cells in the vessel wall and accompanied by the production of a wide range of chemokines, cytokines, and growth factors. These factors regulate the turnover and differentiation of immigrating and resident cells, eventually influencing plaque development. One of the key regulators of inflammation is the transcription factor nuclear factor κB (NF-κB), which, for a long time, has been regarded as a proatherogenic factor, mainly because of its regulation of many of the proinflammatory genes linked to atherosclerosis. NF-κB may play an important role in guarding the delicate balance of the atherosclerotic process as a direct regulator of proinflammatory and anti-inflammatory genes and as a regulator of cell survival and proliferation. Here we address recent literature on the function of NF-κB in inflammatory responses and its relation to atherosclerosis.
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Cites
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Cited by
Negre‐Salvayre, A., Coatrieux, C., Ingueneau, C., & Salvayre, R. (2008) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707395 · Cited by 641
Endothelial Cell-Specific NF-κB Inhibition Protects Mice from Atherosclerosis
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Self-citationForsythe, C. E., Phinney, S. D., Fernandez, M. L., Quann, E. E., Wood, R. J., Bibus, D. M., Kraemer, W. J., Feinman, R. D., & Volek, J. S. (2008) · Lipids · doi:10.1007/s11745-007-3132-7 · Cited by 371
Li, Y., Reddy, M. A., Miao, F., Shanmugam, N., Yee, J.-K., Hawkins, D., Ren, B., & Natarajan, R. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m802800200 · Cited by 353
Drager, L. F., Polotsky, V. Y., & Lorenzi-Filho, G. (2011) · Chest · doi:10.1378/chest.10-2223 · Cited by 322
Metadata
- Authors
- de Winther, M. P. J., Kanters, E., Kraal, G., & Hofker, M. H.
- Venue
- Arteriosclerosis, Thrombosis, and Vascular Biology
- Published
- 2005-05
- Volume
- 25
- Issue
- 5
- Pages
- 904-914
- ISSN
- 1079-5642 (ISSN-L)
- 1524-4636
- OpenAlex
- W2120058838
- Cited by
- 575
- References
- 12
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- green
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- de Winther, M. P. J., Kanters, E., Kraal, G., & Hofker, M. H. (2005). Nuclear Factor κB Signaling in Atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.0000160340.72641.87
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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