PAI-1 and the Metabolic Syndrome: Links, Causes, and Consequences

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Increased oxidative stress in obesity and its impact on metabolic syndrome

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Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice

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The Metabolic Syndrome: Time for a Critical Appraisal

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Hemostatic Factors and the Risk of Myocardial Infarction or Sudden Death in Patients with Angina Pectoris

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A transgenic model of visceral obesity and the metabolic syndrome

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Fibrinolysis and the risk of venous and arterial thrombosis

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Beneficial Effects of Sarpogrelate and Rosuvastatin in High Fat Diet/Streptozotocin-Induced Nephropathy in Mice

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Synergy between plasminogen activator inhibitor-1, α-synuclein, and neuroinflammation in Parkinson’s disease

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Plasminogen activator receptor assemblies in cell signaling, innate immunity, and inflammation

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New markers in metabolic syndrome

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Day/Night Rhythm of Hemostatic Factors in Obstructive Sleep Apnea

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Adipokine Dysregulation and Insulin Resistance with Atherosclerotic Vascular Disease: Metabolic Syndrome or Independent Sequelae?

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The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes

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Assays to quantify fibrinolysis: strengths and limitations. Communication from the International Society on Thrombosis and Haemostasis Scientific and Standardization Committee on fibrinolysis

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Impaired glucose metabolism and type 2 diabetes are associated with hypercoagulability: potential role of central adiposity and low-grade inflammation – The Hoorn Study

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The Role of PAI-1 and Adiponectin on the Inflammatory State and Energy Balance in Obese Adolescents with Metabolic Syndrome

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Small Airways Disease, Biomarkers and COPD: Where are We?

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Biomarkers of Metabolic Syndrome: Biochemical Background and Clinical Significance

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PAI-1: A Major Player in the Vascular Dysfunction in Obstructive Sleep Apnea?

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Metabolically Protective Cytokines Adiponectin and Fibroblast Growth Factor-21 Are Increased by Acute Overfeeding in Healthy Humans

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Local Production of Soluble Urokinase Plasminogen Activator Receptor and Plasminogen Activator Inhibitor‐1 in the Coronary Circulation Is Associated With Coronary Endothelial Dysfunction in Humans

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Metabolic syndrome and the plasma proteome: from association to causation

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Bioactive dietary components—Anti‐obesity effects related to energy metabolism and inflammation

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Elevated plasminogen activator inhibitor 1 in sleep apnea and its relation to the metabolic syndrome: an investigation in 2 different study samples

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Mechanisms affecting brain remodeling in depression: do all roads lead to impaired fibrinolysis?

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Resveratrol Suppresses PAI-1 Gene Expression in a HumanIn VitroModel of Inflamed Adipose Tissue

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Plasminogen activator inhibitor-1 is elevated in patients with COPD independent of metabolic and cardiovascular function

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Plasminogen Activator Inhibitor-1 Level Correlates with Lipoprotein Subfractions in Obese Nondiabetic Subjects

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Adipokines (adiponectin and plasminogen activator inhhibitor-1) in metabolic syndrome

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PAI-1 antagonists: the promise and the peril.

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Association of dietary patterns with serum adipokines among Japanese: a cross-sectional study

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Oral application of a periodontal pathogen impacts SerpinE1 expression and pancreatic islet architecture in prediabetes

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Tissue-specific PAI-1 gene expression and glycosylation pattern in insulin-resistant old rats

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The Role of Fibrinolytic System in Health and Disease

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Is the neck circumference an emergent predictor for inflammatory status in obese adults?

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Metabolic syndrome and endothelial fibrinolytic capacity in obese adults

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The association between metabolic syndrome and vascular endothelial dysfunction in adolescents

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The Metabolic Syndrome Puzzles; Possible Pathogenesis and Management

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Metabolic syndrome: A review of emerging markers and management

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Application of proteomics technology in adipocyte biology

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Whole grain wheat sourdough bread does not affect plasminogen activator inhibitor-1 in adults with normal or impaired carbohydrate metabolism

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Caloric Restriction as a Strategy to Improve Vascular Dysfunction in Metabolic Disorders

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Structural Equation Modeling of Gene-Environment Interactions in Coronary Heart Disease

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Systemic inflammation after spinal cord injury: A review of biological evidence, related health risks, and potential therapies

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Prevalence, components, and correlates of metabolic syndrome (MetS) among elderly Muscovites

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Novel Risk Factors of Cardiovascular Disease and their Associations between Obesity, Physical Activity and Physical Fitness

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Dietary Blueberry and Soluble Fiber Improve Serum Antioxidant and Adipokine Biomarkers and Lipid Peroxidation in Pregnant Women with Obesity and at Risk for Gestational Diabetes

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Human visceral adipose tissue and the plasminogen activator inhibitor type 1

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PAI-1 and TNF-α profiles of adipose tissue in obese cardiovascular disease patients.

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Plasminogen Activator Inhibitor‐1 and Diagnosis of the Metabolic Syndrome in a West African Population

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Insulin resistance and inflammation markers in myocardial infarction

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Obésité, inflammation et insulinorésistance : quel rôle pour les adipokines ?

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The Metabolic Syndrome: An Overview and Proposed Mechanisms

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Bison meat has a lower atherogenic risk than beef in healthy men

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Metabolic factors in the regulation of hypothalamic innate immune responses in obesity

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The effect of mate tea (Ilex paraguariensis) on metabolic and inflammatory parameters in high-fat diet-fed Wistar rats

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Blood biomarkers and measures of pulmonary function–A study from the Swedish twin registry

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Lifestyle Changes Followed by Bariatric Surgery Lower Inflammatory Markers and the Cardiovascular Risk Factors C3 and C4

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The Plasminogen System and Transforming Growth Factor-β in Subjects With Obstructive Sleep Apnea Syndrome: Effects of CPAP Treatment

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Increased Sensitivity of the Circadian System to Temporal Changes in the Feeding Regime of Spontaneously Hypertensive Rats - A Potential Role for Bmal2 in the Liver

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Contribution of Genetic and Metabolic Syndrome to Omental Adipose Tissue PAI-1 Gene mRNA and Plasma Levels in Obesity

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Pathophysiology of Progressive Renal Disease

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Plasminogen activator inhibitor-1 mediate downregulation of adiponectin in type 2 diabetes patients with metabolic syndrome

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Elevated plasma factor XI predicts cardiovascular events in patients with type 2 diabetes: a long-term observational study

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PAI-1 Levels are Related to Insulin Resistance and Carotid Atherosclerosis in Subjects with Familial Combined Hyperlipidemia

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Effect of the small molecule plasminogen activator inhibitor‐1 (PAI‐1) inhibitor, PAI‐749, in clinical models of fibrinolysis

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The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels

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Rs5918ITGB3 Polymorphism, Smoking, and BMI as Risk Factors for Early Onset and Recurrence of DVT in Young Women

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Metabolic, inflammatory and adipokine differences on overweight/obese children with and without metabolic syndrome: A cross-sectional study

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Adipocytokines as features of the metabolic syndrome determined using confirmatory factor analysis

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Meta-Review of Protein Network Regulating Obesity Between Validated Obesity Candidate Genes in the White Adipose Tissue of High-Fat Diet-Induced Obese C57BL/6J Mice

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Adolescents with Classical Polycystic Ovary Syndrome Have Alterations in the Surrogate Markers of Cardiovascular Disease but Not in the Endothelial Function. The Possible Benefits of Metformin

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Levels of PAI-1 and outcome after electrical cardioversion for atrial fibrillation

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Extracellular vesicles from periodontal pathogens regulate hepatic steatosis via Toll‐like receptor 2 and plasminogen activator inhibitor‐1

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Cranberries ( Oxycoccus quadripetalus ) inhibit pro-inflammatory cytokine and chemokine expression in 3T3-L1 adipocytes

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Clinical research of Yiqi Sanju Formula in treating central obese men at high risk of metabolic syndrome

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The study of markers of endothelial dysfunction in metabolic syndrome

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Prospective assessment of fibrinolysis in morbid obesity: tissue plasminogen activator resistance improves after bariatric surgery

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Thrombophilia–hypofibrinolysis and atherothrombotic cardiovascular disease ≤ age 45 years

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Suppression of Fibrinolysis and Hypercoagulability, Severity of Hypoxemia, and Mortality in COVID-19 Patients: A Retrospective Cohort Study

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Circulating microparticle subpopulation in metabolic syndrome: relation to oxidative stress and coagulation markers

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Risk Factors of Metabolic Syndrome among Polish Nurses

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Adipokines and the clinical laboratory: what to measure, when and how?

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Discovery of four plasmatic biomarkers potentially predicting cardiovascular outcome in peripheral artery disease

Kremers, B. M. M., Posma, J. N., Heitmeier, S., Glunz, J., ten Cate, H., Pallares Robles, A., Daemen, J. H. C., ten Cate-Hoek, A. J., Mees, B. M. E., & Spronk, H. M. H. (2022) · Scientific Reports · doi:10.1038/s41598-022-23260-3 · Cited by 17

Elevated expression of urotensin II and its receptor in skeletal muscle of diabetic mouse

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Early genetic responses in rat vascular tissue after simulated diving

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Early Effects of Treatment Low-Dose Atorvastatin on Markers of Insulin Resistance and Inflammation in Patients with Myocardial Infarction

Gruzdeva, O. V., Учасова, Е. Г., Dyleva, Y. A., Евгеньевна, А. О., Каретникова, В. Н., & Барбараш, О. Л. (2016) · Frontiers in Pharmacology · doi:10.3389/fphar.2016.00324 · Cited by 18

Longitudinal associations between cardiovascular biomarkers and metabolic syndrome during puberty: the PUBMEP study

González‐Gil, E. M., Anguita‐Ruiz, A., Kalén, A., de Lamas, C., Rupérez, A. I., Vázquez‐Cobela, R., Flores‐Rojas, K., Gil, Á., Gil‐Campos, M., Bueno, G., et al. (2022) · European Journal of Pediatrics · doi:10.1007/s00431-022-04702-6 · Cited by 17

Detection and characterisation of microcirculatory abnormalities in the skin of diabetic patients with microvascular complications

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Activation of cardiac renin–angiotensin system and plasminogen activator inhibitor-1 gene expressions in oral contraceptive-induced cardiometabolic disorder

Olatunji, L. A., Usman, T. O., Seok, Y. M., & Kim, I. (2016) · Archives of Physiology and Biochemistry · doi:10.3109/13813455.2016.1160935 · Cited by 17

The Impact of Cigarette Smoking on 24‐Hour Blood Pressure, Inflammatory and Hemostatic Activity, and Cardiovascular Risk in Japanese Hypertensive Patients

Yano, Y., Hoshide, S., Shimada, K., & Kario, K. (2012) · Journal of Clinical Hypertension · doi:10.1111/jch.12047 · Cited by 17

Food deprivation induces adipose plasminogen activator inhibitor-1 (PAI-1) expression without accumulation of plasma PAI-1 in genetically obese and diabetic db/db mice

Oishi, K., Ohkura, N., Matsuda, J., & Ishida, N. (2007) · Thrombosis and Haemostasis · doi:10.1160/th07-04-0268 · Cited by 17

Soluble CD40 Ligand, Plasminogen Activator Inhibitor-1 and Thrombin-Activatable Fibrinolysis Inhibitor-1-Antigen in Normotensive Type 2 Diabetic Subjects without Diabetic Complications

Yener, S., Çömlekçi, A., Akıncı, B., Demir, T., Yüksel, F., Özcan, M. A., Bayraktar, F., & Yeşil, S. (2009) · Medical Principles and Practice · doi:10.1159/000215722 · Cited by 17

Long-term in vivo survival of 3D-bioprinted human lipoaspirate-derived adipose tissue: proteomic signature and cellular content

Säljö, K., Apelgren, P., Orrhult, L. S., Li, S., Amoroso, M., Gatenholm, P., & Kölby, L. (2021) · Adipocyte · doi:10.1080/21623945.2021.2014179 · Cited by 16

Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific manner

Savva, C., Helguero, L. A., Gonzalez-Granillo, M. A., Melo, T., Couto, D., Angelin, B., Domingues, M. R., Li, X., Kutter, C., & Korach-André, M. (2022) · Communications Biology · doi:10.1038/s42003-022-04022-3 · Cited by 18

Diagnostic Power of Circulatory Metabolic Biomarkers as Metabolic Syndrome Risk Predictors in Community-Dwelling Older Adults in Northwest of England (A Feasibility Study)

Hassannejad, R., Sharrouf, H., Haghighatdoost, F., Kirk, B., & Amirabdollahian, F. (2021) · Nutrients · doi:10.3390/nu13072275 · Cited by 16

Hypertension, hypercoagulability and the metabolic syndrome: A cluster of risk factors for cardiovascular disease

Mao, X., Ait‐Aissa, K., Lagrange, J., Youcef, G., & Louis, H. (2012) · Bio-Medical Materials and Engineering · doi:10.3233/bme-2012-0688 · Cited by 15

Plasminogen activator inhibitor-1 and thrombin activatable fibrinolysis inhibitor levels in non-alcoholic steatohepatitis

Yener, S., Akarsu, M., Demir, T., Akıncı, B., Sağol, Ö., Bayraktar, F., Özcan, M. A., Tankurt, E., & Yeşil, S. (2007) · Journal of Endocrinological Investigation · doi:10.1007/bf03349221 · Cited by 16

The Pro/Pro genotype of the p53 codon 72 polymorphism modulates PAI-1 plasma levels in ageing

Testa, R., Bonfigli, A. R., Salvioli, S., Invidia, L., Pierini, M., Sirolla, C., Marra, M., Testa, I., Fazioli, F., Recchioni, R., et al. (2009) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2009.06.001 · Cited by 16

Fibrinolysis and von Willebrand factor in Alzheimer's disease and vascular dementia – a case-referent study

Hagnelius, N.-O., Boman, K., & Nilsson, T. (2009) · Thrombosis Research · doi:10.1016/j.thromres.2009.10.001 · Cited by 16

Pleiotrophin deficiency protects against high-fat diet-induced neuroinflammation: Implications for brain mitochondrial dysfunction and aberrant protein aggregation

Cañeque‐Rufo, H., Sánchez‐Alonso, M. G., Zuccaro, A., Sevillano, J., Ramos, P., & Herradón, G. (2022) · Food and Chemical Toxicology · doi:10.1016/j.fct.2022.113578 · Cited by 14

Altered Daytime Fluctuation Pattern of Plasminogen Activator Inhibitor 1 in Type 2 Diabetes Patients with Coronary Artery Disease: A Strong Association with Persistently Elevated Plasma Insulin, Increased Insulin Resistance, and Abdominal Obesity

Lalic, K. S., Jotić, A., Rajkovic, N., Singh, S., Stošić, L., Popović, L., Lukić, L., Milicic, T. J., Seferović, J. P., Macesic, M. V., et al. (2015) · International Journal of Endocrinology · doi:10.1155/2015/390185 · Cited by 15

IRAP deficiency attenuates diet-induced obesity in mice through increased energy expenditure

Niwa, M., Numaguchi, Y., Ishii, M., Kuwahata, T., Kondo, M., Shibata, R., Miyata, K., Oike, Y., & Murohara, T. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.12.071 · Cited by 14

Mechanisms Linking the Metabolic Syndrome and Cardiovascular Disease: Role of Hepatic Insulin Resistance

Meshkani, R., & Adeli, K. (2009) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 15

Impaired fibrinolysis without hypercoagulability characterises patients with non-alcoholic fatty liver disease

Eriksen, P. L., Thomsen, K. L., Sørensen, M., Vilstrup, H., & Hvas, A. (2022) · Thrombosis Research · doi:10.1016/j.thromres.2022.02.023 · Cited by 15

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Hemostatic abnormalities associated with obesity and the metabolic syndrome

Juhan-Vague, I., & Alessi, M. (2005) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2005.01281.x · Cited by 1

Metabolic syndrome, plasminogen activator inhibitor (pai-1) and atherosclerosis

Mavri, A. (2005) · DOAJ (DOAJ: Directory of Open Access Journals)

Povezava med metabolnim sindromom, inhibitorjem aktivatorja plazminogena (pai-1) in aterosklerozo

Mavri, A. (2005) · Slovenian Medical Journal

Plasminogen activator inhibitor-1 and metabolic syndrome

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